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    • 11. 发明授权
    • Off-line teaching apparatus
    • 离线教学仪器
    • US06631308B1
    • 2003-10-07
    • US09659588
    • 2000-09-11
    • Masakatsu KanekoShinji Aoki
    • Masakatsu KanekoShinji Aoki
    • G05B1904
    • G05B19/425G05B2219/35499G05B2219/36017G05B2219/36183G05B2219/39396G05B2219/40394
    • An off-line teaching apparatus comprises an operation command-receiving means for receiving an operation command inputted via an input/output port from a key input device or a coordinate input device and successively storing the operation command in a buffer; an operation command-reading means for successively reading the operation command stored in the buffer; an operation command-counting means for counting a number of operation commands stored in the buffer; and a confirmation sound-generating means for generating confirmation sound upon receipt of the operation, command by the operation command-receiving means when a counted value obtained by the operation command-counting means is not less than a predetermined number. Accordingly, the operator can be informed, in real time, of the fact that the system responds to the input of the operation command from the operator. Thus, it is possible to improve the operability of the off-line teaching.
    • 离线示教装置包括操作命令接收装置,用于从键输入装置或坐标输入装置接收经由​​输入/输出端口输入的操作命令,并将操作命令连续地存储在缓冲器中; 操作命令读取装置,用于连续读取存储在缓冲器中的操作命令; 操作命令计数装置,用于对存储在缓冲器中的操作命令的数量进行计数; 以及确认声音产生装置,用于当由操作命令计数装置获得的计数值不小于预定数量时,在接收到操作时产生确认声音,并由操作命令接收装置发出命令。 因此,可以实时地通知操作者系统响应于来自操作者的操作命令的输入。 因此,可以提高离线教学的可操作性。
    • 13. 发明授权
    • Method for setting tool-based working condition in off-line teaching
    • 在离线教学中设置工具工作条件的方法
    • US06256552B1
    • 2001-07-03
    • US09146071
    • 1998-09-02
    • Shinji AokiMasakatsu Kaneko
    • Shinji AokiMasakatsu Kaneko
    • G06F1900
    • G05B19/40937B23K11/252Y02P90/265
    • A method for setting a tool-based working condition in off-line teaching makes it possible to automatically set an optimum tool-based working condition while referring to specifications of a tool and workpiece-based working conditions so that reduced operation time required for the off-line teaching is efficiently realize. The method comprises steps of designating a welding point on CAD data of a workpiece; a step of retrieving one or more part codes concerning the welding point; a step of obtaining a combination of attribute codes necessary for the welding concerning the retrieved one or more part codes; a step of deciding a workpiece-based working condition on the basis of the obtained combination of attribute codes; a step of judging whether or not the decided workpiece-based working condition is included in specified specifications of a tool; and a step of retrieving a tool-based working condition suitable for the workpiece-based working condition from the specifications of the tool if the workpiece-based working condition is included in the specifications of the tool, so that teaching data is reflected thereby.
    • 一种用于在离线教学中设定基于工具的工作条件的方法使得可以在参考工具的规格和基于工件的工作条件的同时自动设置最佳的基于工具的工作状态,从而减少关闭所需的操作时间 线上教学有效实现。 该方法包括以下步骤:指定工件的CAD数据上的焊接点; 检索关于焊接点的一个或多个部件代码的步骤; 获得关于所检索的一个或多个部件代码的焊接所需的属性代码的组合的步骤; 基于所获得的属性代码的组合来确定基于工件的工作条件的步骤; 判断所确定的基于工件的工作状态是否包括在工具的规定规格中的步骤; 以及如果基于工件的工作条件包括在工具的规格中,则从工具的规格检索适合于基于工件的工作条件的基于工具的工作条件的步骤,从而反映教学数据。
    • 14. 发明授权
    • Off-line teaching apparatus
    • 离线教学仪器
    • US06226567B1
    • 2001-05-01
    • US09144472
    • 1998-08-31
    • Masakatsu KanekoShinji Aoki
    • Masakatsu KanekoShinji Aoki
    • G05B1500
    • G05B19/425G05B2219/35499G05B2219/36017G05B2219/36183G05B2219/39396G05B2219/40394
    • An off-line teaching apparatus comprises an operation command-receiving means for receiving an operation command inputted via an input/output port from a key input device or a coordinate input device and successively storing the operation command in a buffer; an operation command-reading means for successively reading the operation command stored in the buffer; an operation command-counting means for counting a number of operation commands stored in the buffer; and a confirmation sound-generating means for generating confirmation sound upon receipt of the operation command by the operation command-receiving means when a counted value obtained by the operation command-counting means is not less than a predetermined number. Accordingly, the operator can be informed, in real time, of the fact that the system responds to the input of the operation command from the operator. Thus, it is possible to improve the operability of the off-line teaching.
    • 离线示教装置包括操作命令接收装置,用于从键输入装置或坐标输入装置接收经由​​输入/输出端口输入的操作命令,并将操作命令连续地存储在缓冲器中; 操作命令读取装置,用于连续读取存储在缓冲器中的操作命令; 操作命令计数装置,用于对存储在缓冲器中的操作命令的数量进行计数; 以及确认声音发生装置,用于当由操作命令计数装置获得的计数值不小于预定数量时,通过操作命令接收装置接收到操作命令时产生确认声音。 因此,可以实时地通知操作者系统响应于来自操作者的操作命令的输入。 因此,可以提高离线教学的可操作性。
    • 16. 发明授权
    • Antibacterial compound
    • 抗菌化合物
    • US07157442B2
    • 2007-01-02
    • US10080191
    • 2002-02-19
    • Hitoshi HotodaMasakatsu KanekoMasatoshi InukaiYasunori MuramatsuYukio UtsuiSatoshi Ohya
    • Hitoshi HotodaMasakatsu KanekoMasatoshi InukaiYasunori MuramatsuYukio UtsuiSatoshi Ohya
    • A61K31/70A61K31/553A61K31/504C07D239/02C07D401/00
    • C07H19/06
    • The present invention relates to a compound of formula (I) (wherein R1 and R2 represent an aryl group, a heterocyclic group, an alkyl group, an alkenyl group and the like which are optionally substituted, R3 represents a hydrogen atom or a hydroxyl group, and X1 and X2 represent an oxygen atom or a sulfur atom, or a nitrogen atom which may be substituted), a pharmaceutically acceptable derivative thereof or a salt thereof.The present invention also relates to a pharmaceutical composition comprising a compound described above as an active ingredient for the prevention or treatment of bacterial infections.The present invention includes the use of a compound described above in order to prepare a medicament effective in the prevention or treatment of bacterial infections.The present invention is concerned with a method for the prevention or treatment of bacterial infections in warm-blooded animals comprising administering a pharmacologically effective amount of a compound described above to them
    • 本发明涉及式(I)化合物(其中R 1和R 2表示芳基,杂环基,烷基,烯基和 任选被取代的R 3表示氢原子或羟基,X 1和X 2表示氧原子或 硫原子或可被取代的氮原子),其药学上可接受的衍生物或其盐。 本发明还涉及包含上述化合物作为预防或治疗细菌感染的活性成分的药物组合物。 本发明包括使用上述化合物以制备有效预防或治疗细菌感染的药物。 本发明涉及一种预防或治疗温血动物细菌感染的方法,其包括将药理学有效量的上述化合物给予它们
    • 17. 发明授权
    • Method of and system for generating teaching data for robots
    • 用于生成机器人教学数据的方法和系统
    • US5341458A
    • 1994-08-23
    • US942983
    • 1992-09-10
    • Masakatsu KanekoHidetaka NosseKatsumi Takeishi
    • Masakatsu KanekoHidetaka NosseKatsumi Takeishi
    • B25J9/18G05B19/425G06F15/46G05B17/00
    • G05B19/425
    • In a method and system for generating teaching data for robots, a plurality of virtual target points are disposed in the vicinity of each of target points allowable on design, where a tool center point of a robot is to be positioned. The virtual target points and the original target point are combined into "target points taken in a broad sense". Each of the target points taken in the broad sense is given as a point which has been confirmed as a tool-attainable point on an off-line teaching apparatus. When a necessary correction is made on-line to teaching data generated by the off-line teaching apparatus, including as data the target points taken in the broad sense, an operator can select a suitable point from the target points taken in the broad sense and carry out a process of correcting the teaching data, regarding the suitable point as being a starting point.
    • 在用于生成机器人的教学数据的方法和系统中,将多个虚拟目标点设置在设计中允许的每个目标点附近,其中机器人的工具中心点将被定位。 虚拟目标点和原始目标点被组合成“广义意义上的目标点”。 给出了广义意义上的每个目标点作为在离线教学装置上被确认为可达到工具点的点。 当在线地进行对由离线教学装置生成的数据进行必要的校正时,包括作为数据的广义意义上的目标点,操作者可以从广义的目标点中选择合适的点, 执行校正教学数据的过程,将适合的点作为起点。
    • 19. 发明授权
    • Nucleoside and oligonucleotide analogues
    • 核苷和寡核苷酸类似物
    • US07335765B2
    • 2008-02-26
    • US09925673
    • 2001-08-09
    • Masakatsu KanekoKoji MoritaTakeshi Imanishi
    • Masakatsu KanekoKoji MoritaTakeshi Imanishi
    • C07H19/00C07H21/00C07H19/06C70H19/16
    • C07H19/10C07H19/06C07H19/16C07H19/20Y02P20/55Y10T436/143333
    • A compound of the formula (1): wherein R1 and R2 are the same or different and represent a hydrogen atom, a hydroxyl protecting group, a phosphate group, or —P(R3)R4, wherein R3 and R4 are the same or different and represent a hydroxyl group, an amino group, an alkoxy group having from 1 to 4 carbon atoms, a cyanoalkoxy group having from 1 to 5 carbon atoms or an amino group substituted by an alkyl group having from 1 to 4 carbon atoms; A represents an alkylene group having from 1 to 4 carbon atoms and B represents a purin-9-yl group, a 2-oxo-pyrimidin-1-yl group, a substituted purin-9-yl group or a substituted 2-oxo-pyrimidin-1-yl group having a substituent α selected from the group consisting of a hydroxyl group which may be protected, an alkoxy group having from 1 to 4 carbon atoms, a mercapto group which may be protected, an alkylthio group having from 1 to 4 carbon atoms, an alkoxy group having from 1 to 4 carbon atoms, an amino group which may be protected, a mono- or di-alkylamino group which may be substituted by an alkyl group having from 1 to 4 carbon atoms, an alkyl group having from 1 to 4 carbon atoms and a halogen atom; or a salt thereof.
    • 式(1)的化合物:其中R 1和R 2相同或不同,表示氢原子,羟基保护基,磷酸基或 -P(R 3)R 4,其中R 3和R 4相同或不同,表示 羟基,氨基,具有1至4个碳原子的烷氧基,具有1至5个碳原子的氰基烷氧基或被具有1至4个碳原子的烷基取代的氨基; A表示具有1至4个碳原子的亚烷基,B表示嘌呤-9-基,2-氧代 - 嘧啶-1-基,取代的嘌呤-9-基或取代的2-氧代 - 具有选自可被保护的羟基,具有1至4个碳原子的烷氧基,可被保护的巯基的取代基的嘧啶-1-基,具有1至4个碳原子的烷硫基, 4个碳原子,具有1至4个碳原子的烷氧基,可被保护的氨基,可以被具有1至4个碳原子的烷基取代的一烷基或二烷基氨基,烷基 具有1至4个碳原子和卤素原子; 或其盐。