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131. 发明授权

US6113579A Catheter tip designs and methods for improved stent crossing 失效
标题翻译：导管尖端设计和改进支架穿越的方法
公开(公告)号：US6113579A
公开(公告)日：2000-09-05
申请号：US34421
申请日：1998-03-04
申请人： Tracee E. J. Eidenschink , Timothy J. Mickley , Christopher R. Larson , Steven P. Mertens , Charles L. Euteneuer
发明人： Tracee E. J. Eidenschink , Timothy J. Mickley , Christopher R. Larson , Steven P. Mertens , Charles L. Euteneuer
IPC分类号： A61F2/958 , A61M25/00 , A61M25/04 , A61M5/00 , A61M29/00
CPC分类号： A61M25/0068 , A61M25/0074 , A61M25/008 , A61M2025/0081 , A61M2025/1093 , A61M25/04 , A61M25/10
摘要： A catheter is disclosed which includes an over-the-wire type balloon catheter with a guide wire wherein the catheter includes a polyethylene inner tube and an outer tube having a relatively stiff proximal outer section, a midshaft section of lesser stiffness, and a tapering distal outer section of the least stiffness. An inflatable balloon is connected to the distal ends of the inner tube and the outer tube. The guide wire may be removed from and inserted into the guide wire lumen at either end of the catheter.
摘要翻译：公开了一种导管，其包括具有导丝的超线型气囊导管，其中导管包括聚乙烯内管和具有相对刚性的近端外部部分的外管，具有较小刚度的中轴部分和锥形远端外截面刚度最小。可膨胀气囊连接到内管和外管的远端。导丝可以从导管的任一端移除并插入导丝管内。

132. 发明授权

US6052612A Catheter for media injection 失效
标题翻译：导管用于媒体注射
公开(公告)号：US6052612A
公开(公告)日：2000-04-18
申请号：US49841
申请日：1998-03-27
申请人： Jawahar M. Desai
发明人： Jawahar M. Desai
IPC分类号： A61M25/00 , A61M25/04 , A61B6/00
CPC分类号： A61M25/007 , A61M25/0043 , A61M25/0074 , A61M25/0075 , A61M25/04 , A61M2025/0057 , A61M2025/0073 , A61M2025/0079 , A61M25/0068 , A61M25/008
摘要： An improved endocardial catheter includes a plurality of longitudinally extending openings adjacent intermediate portions at its distal end. The catheter is actuable from a retracted or collapsed mode, wherein the sealed openings are arranged around the tubular catheter surface, to an expanded mode. The plurality of longitudinal openings in the catheter wall enable radial expansion of the tubular surface at the distal end so that intermediate portions of the tubular catheter surface are moved to an operative position radially outward from their position in the retracted mode. In the expanded position, the intermediate portions form wings around the distal end, revealing a cavity within the tubular catheter for the release of contrast material or other fluid into endocardial sites through the longitudinal openings.
摘要翻译：改进的心内膜导管包括在其远端处邻近中间部分的多个纵向延伸的开口。导管可从收缩或收缩模式致动，其中密封开口围绕管状导管表面布置成扩展模式。导管壁中的多个纵向开口使远端的管状表面能够径向膨胀，使得管状导管表面的中间部分在缩回模式下从其位置向径向外侧移动到工作位置。在扩展位置，中间部分围绕远端形成翼，露出管状导管内的空腔，用于通过纵向开口将对比材料或其它流体释放到心内膜部位。

133. 发明授权

US6002955A Stabilized electrophysiology catheter and method for use 失效
标题翻译：稳定电生理导管及其使用方法
公开(公告)号：US6002955A
公开(公告)日：1999-12-14
申请号：US949408
申请日：1997-10-14
申请人： Stephan Willems , Christian Weiss , Frank Nguyen , John W. Gaiser , Scott A. McIntosh
发明人： Stephan Willems , Christian Weiss , Frank Nguyen , John W. Gaiser , Scott A. McIntosh
IPC分类号： A61M25/00 , A61M25/01 , A61N1/05 , A61B5/04
CPC分类号： A61M25/0147 , A61M25/0041 , A61M25/0068 , A61M25/0144 , A61M25/0152 , A61M2025/0161 , A61M25/008 , A61M25/0082
摘要： A stabilized electrophysiology catheter (4) includes a main body portion (16) and a flexible tip portion (18). A plurality of electrodes (24, 26) are positioned along the tip portion. The tip portion includes a main section (20) and a pre-curved, offset, reverse-angle anchor section (22) at its distal end. The anchor section is shaped to engage with and anchor to a coronary opening, typically the coronary sinus opening (48) in the right atrium or a pulmonary vein opening (82) in the left atrium, for stabilized mapping and ablation of the right atrium or the left atrium. A manipulator wire (36) is used to radially deflect the tip portion in a first direction (40). When introduced through the superior vena cava (46), the tip portion forms a generally J-shape. When introduced through the inferior vena cava (54), the tip portion is deflected more than 360.degree..
摘要翻译：稳定的电生理学导管（4）包括主体部分（16）和柔性尖端部分（18）。多个电极（24,26）沿着尖端部分定位。尖端部分在其远端包括主部分（20）和预弯曲偏移的反向角锚固部分（22）。锚定部分成形为与冠状开口（通常是右心房中的冠状窦开口（48）或左心房中的肺静脉开口（82））接合并锚固，用于稳定地映射和消融右心房或左心房。使用操纵器导线（36）沿第一方向（40）径向偏转尖端部分。当通过上腔静脉（46）引入时，尖端部分形成大致J形。当通过下腔静脉（54）引入时，尖端部分偏转超过360度。

134. 发明授权

US5899891A Catheter 失效
标题翻译：导管
公开(公告)号：US5899891A
公开(公告)日：1999-05-04
申请号：US706608
申请日：1996-09-05
申请人： N. Sandor Racz
发明人： N. Sandor Racz
IPC分类号： A61B17/34 , A61M25/00 , A61M25/09 , A61M5/00
CPC分类号： A61M25/008 , A61M25/0017 , A61M25/0043 , A61B17/3401 , A61M25/0054 , A61M25/007 , A61M25/0097
摘要： Catheters which utilize a flexible tube that has been modified at one end or both ends. Such modifications involve modifying a tube end to increase rigidity and strength (while maintaining some flexibility), or involve special placement of an intraluminal cord within the tube. One such catheter has a tube (20) with a cord (26) running therethrough wherein a portion of the tube's proximal end has been reinforced (30), preferably, in such a manner that the reinforced portion of the tube remains flexible. Similarly, another catheter includes a tube having an associated intraluminal cord, wherein the cord is affixed to the interior of the tube's proximal end. Another catheter has a tube and intraluminal cord with an enlarged end (e.g. a ball (28)) extending from the tube's distal end, and is modified by incorporating, within the tube's distal end, a spring (30). The thus placed spring (30) acts to increase the rigidity of the tip of the device, and interacts with the ball if need be to collect a portion of the tube which may break off from the remainder of the tube after placement.
摘要翻译：使用在一端或两端已被修改的柔性管的导管。这种修改包括修改管端以增加刚度和强度（同时保持一定的灵活性），或者涉及将管腔内特别放置在管内。一个这样的导管具有管（20），管（26）穿过其中，其中管的近端的一部分已经被加强（30），优选地使得管的加强部分保持柔性。类似地，另一个导管包括具有相关联的腔内软管的管，其中，绳固定在管的近端的内部。另一个导管具有管和腔内线，其具有从管的远端延伸的扩大端（例如球（28）），并且通过在管的远端内并入弹簧（30）而被修改。如此放置的弹簧（30）用于增加装置的尖端的刚度，并且如果需要收集在放置之后可能与管的其余部分分离的管的一部分，则与球相互作用。

135. 发明授权

US5882332A Drug infusion catheter and method 失效
标题翻译：药物输液导管及方法
公开(公告)号：US5882332A
公开(公告)日：1999-03-16
申请号：US870562
申请日：1997-06-06
申请人： Bandula Wijay
发明人： Bandula Wijay
IPC分类号： A61M25/00 , A61M29/02 , A61M31/00
CPC分类号： A61M25/0068 , A61M25/00 , A61M29/02 , A61M2025/0057 , A61M2025/0073 , A61M2025/09183 , A61M2025/1047 , A61M25/0043 , A61M25/0074 , A61M25/008
摘要： A method and apparatus of delivery of a drug (or substance) is disclosed which involves (1) injecting a drug into the tissue of the blood vessel; (2) maintaining the delivery system as symmetrical as possible in tortuous blood vessels, and (3) providing a preferably constant flow of blood during the drug treatment.
摘要翻译：公开了一种递送药物（或物质）的方法和装置，其包括（1）将药物注射到血管的组织中; （2）在曲折的血管中保持输送系统尽可能对称，以及（3）在药物治疗期间提供优选恒定的血液流。

136. 发明授权

US5800378A Medical probe device and method 失效
公开(公告)号：US5800378A
公开(公告)日：1998-09-01
申请号：US618583
申请日：1996-03-20
申请人： Stuart D. Edwards , Ronald G. Lax , Ingemar H. Lundquist , Hugh R. Sharkey
发明人： Stuart D. Edwards , Ronald G. Lax , Ingemar H. Lundquist , Hugh R. Sharkey
IPC分类号： A61B5/01 , A61B10/00 , A61B10/02 , A61B10/06 , A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28 , A61B17/34 , A61B18/00 , A61B18/08 , A61B18/14 , A61B18/18 , A61B18/22 , A61B18/24 , A61B19/00 , A61F7/00 , A61M1/00 , A61M3/02 , A61M25/00 , A61M25/092 , A61M25/14 , A61N1/06 , A61N1/40 , A61N5/02 , A61N5/04 , A61N5/06 , A61B17/20
CPC分类号： A61N5/02 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/18 , A61B18/1815 , A61N1/06 , A61N1/40 , A61N1/403 , A61N5/045 , A61B10/02 , A61B10/0241 , A61B18/082 , A61B18/1206 , A61B18/14 , A61B18/1442 , A61B18/148 , A61B18/24 , A61B2017/00084 , A61B2017/00092 , A61B2017/00106 , A61B2017/00274 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2017/22072 , A61B2017/22077 , A61B2017/22082 , A61B2017/248 , A61B2017/2939 , A61B2017/3488 , A61B2018/00005 , A61B2018/00011 , A61B2018/00083 , A61B2018/00095 , A61B2018/00196 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00678 , A61B2018/00702 , A61B2018/00726 , A61B2018/00744 , A61B2018/0075 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00869 , A61B2018/00886 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/00982 , A61B2018/1253 , A61B2018/126 , A61B2018/1273 , A61B2018/128 , A61B2018/1412 , A61B2018/1425 , A61B2018/1861 , A61B2018/2238 , A61B2090/0814 , A61B2090/3614 , A61B2090/3782 , A61B2090/3925 , A61F2007/0054 , A61M2025/0086 , A61M2025/0087 , A61M2025/0089 , A61M2025/009 , A61M2025/0096 , A61M2025/018 , A61M25/0068 , A61M25/0069 , A61M25/008 , A61M25/0082 , A61M3/0279 , A61N5/04
摘要： A medical probe device comprises a catheter having a stylet guide housing with one or more stylet ports in a side wall thereof and a stylet guide for directing a flexible stylet outward through the stylet port and through intervening tissue at a preselected, adjustable angle to a target tissue. The total catheter assembly includes a stylet guide lumen communicating with the stylet port and a stylet positioned in said stylet guide lumen for longitudinal movement from the port through intervening tissue to a target tissue. The stylet can be an electrical conductor enclosed within a non-conductive layer, the electrical conductor being a radiofrequency electrode. Preferably, the non-conductive layer is a sleeve which is axially moveable on the electrical conductor to expose a selected portion of the electrical conductor surface in the target tissue. The stylet can also be a microwave antenna. The stylet can also be a hollow tube for delivering treatment fluid to the target tissue. It can also include a fiber optic cable for laser treatment. The catheter can include one or more inflatable balloons located adjacent to the stylet port for anchoring the catheter or dilation. Ultrasound transponders and temperature sensors can be attached to the probe end and/or stylet. The stylet guide can define a stylet path from an axial orientation in the catheter through a curved portion to a lateral orientation at the stylet port.

137. 发明授权

US5788680A Dual-lumen suction catheter with multiple apertures in the vent lumen 失效
标题翻译：双腔吸入导管，在排气腔内有多个孔
公开(公告)号：US5788680A
公开(公告)日：1998-08-04
申请号：US677390
申请日：1996-07-09
申请人： Gerald Seymour Linder
发明人： Gerald Seymour Linder
IPC分类号： A61M1/00 , A61M25/00
CPC分类号： A61M25/0068 , A61M25/008 , A61M1/008 , A61M2025/0037 , A61M2025/0081 , A61M25/007 , A61M25/0071
摘要： A dual-lumen suction catheter is disclosed consisting of a longitudinally extending pliable tube having separate and independent suction and vent lumens. The proximal end of the catheter has a first open end for the suction lumen and a second, separate open end, for the vent lumen. The catheter is provided with an opening at its distal end through which fluids to be withdrawn from the organ of a patient enter the suction lumen. A plurality of spaced-apart apertures situated in the distal portion of the catheter extend from within the vent lumen through the wall of the pliable tube to the outside surface of the catheter, the apertures being longitudinally displaced from each other and from the distal tip of the catheter. The plurality of apertures are independent of and separate from the suction lumen.
摘要翻译：公开了一种双腔吸入导管，其包括具有独立且独立的吸入和排气腔的纵向延伸的柔韧管。导管的近端具有用于吸入腔的第一开口端和用于排气腔的第二独立开口端。导管在其远端设置有一个开口，通过该开口从患者器官抽出的流体进入吸入腔。位于导管的远端部分中的多个间隔开的孔从通气腔内通过柔韧管的壁延伸到导管的外表面，这些孔彼此纵向移位并且从远端导管。多个孔与吸入腔独立并与分离。

138. 发明授权

US5779699A Slip resistant field focusing ablation catheter electrode 失效
标题翻译：防滑场聚焦消融导管电极
公开(公告)号：US5779699A
公开(公告)日：1998-07-14
申请号：US626750
申请日：1996-03-29
申请人： David Lipson
发明人： David Lipson
IPC分类号： A61B18/00 , A61B18/14 , A61M25/00 , A61N1/00
CPC分类号： A61B18/1492 , A61B2017/003 , A61B2018/00011 , A61B2018/0091 , A61M25/0068 , A61M25/008 , A61M25/0082
摘要： An RF ablation catheter of the type comprising a flexible elongate catheter body having at least one lumen therethrough and having a proximal handle end and a distal end section adapted to be introduced into a heart chamber, at least one electrical conductor extending from the handle to the distal tip section within the at least one lumen for conduction RF energy, and a distal tip electrode coupled to the distal end section of the catheter body and electrically coupled with the at least one electrical conductor. The distal tip electrode is formed with a slip resistant, field focusing exterior contour for maintaining a position of the distal tip electrode bearing against the endocardium of the patient's heart, without penetrating the myocardium thereof, achieved through manipulation of the catheter distal tip section, and focusing ablation energy into the endocardium. The distal tip electrode is formed of a generally cylindrical, electrically conductive, electrode body having a hemispheric end and a tubular side wall at the distal end of the catheter body, and the exterior contour providing means further comprises a plurality of depressions formed by bores or annular or spiral or longitudinally elongated grooves formed in the hemispheric end and/or side wall. The exterior contour additionally assists in cooling the distal tip electrode.
摘要翻译：一种RF消融导管，其包括柔性细长导管主体，其具有穿过其中的至少一个腔，并且具有近端手柄端和适于引入心室的远端部分，至少一个从手柄延伸到用于传导RF能量的至少一个内腔内的远端尖端部分，以及耦合到导管主体的远端部分并与至少一个电导体电耦合的远侧末端电极。远侧末端电极形成有防滑的场聚焦外部轮廓，用于通过操纵导管远端末端部分而保持远侧末端电极轴承抵靠患者心脏的心内膜的位置而不穿透其心肌，以及将消融能量聚焦到心内膜。远侧末端电极由大致圆柱形导电的电极体形成，该电极主体具有在导管主体的远端处的半球端和管状侧壁，并且外部轮廓提供装置还包括多个由孔或形成在半球端和/或侧壁中的环形或螺旋形或纵向细长的槽。外部外形还有助于冷却远端尖端电极。

139. 发明授权

US5769828A Two-stage venous cannula with expandable reinforcing member 失效
标题翻译：具有可扩张加强构件的两级静脉插管
公开(公告)号：US5769828A
公开(公告)日：1998-06-23
申请号：US663563
申请日：1996-06-13
申请人： Kenneth R. Jonkman
发明人： Kenneth R. Jonkman
IPC分类号： A61M1/36 , A61M25/00
CPC分类号： A61M25/0012 , A61M1/3659 , A61M25/0052 , A61M25/0068 , A61M25/007 , A61M2025/0031 , A61M25/0015 , A61M25/008
摘要： A two-staged venous cannula is disclosed. The cannula includes an expandable reinforcing member around the atrial basket that prevents the cannula from kinking or collapsing in the area where the reinforcing member is applied. The reinforcing member preferably consists of an even number of rigid discrete beams of the same length equally spaced about the circumference of a cylinder. In an alternate embodiment, the beams may be equally spaced on the surface of a cone. Alternate spaces between the beams are formed. The alternate spaces between the beams are equally spaced around the circumference of the cannula. The alternate spaces between the beams remain equally spaced around the circumference of the cannula as the reinforcing member is expanded over a larger diameter. This design for the reinforcing member provides space between the beams where holes of the preferred shape, size and orientation can be placed through the cannula without requiring cutting through the material of the reinforcing member.
摘要翻译：公开了一种两级静脉插管。套管包括围绕心房篮的可扩张加强构件，其防止套管在加强构件被施加的区域中扭结或塌陷。加强构件优选地由偶数数量的圆柱体周长等间隔地具有相同长度的刚性离散梁组成。在替代实施例中，梁可以等距分布在锥体的表面上。形成梁之间的交替空间。梁之间的交替空间围绕套管的圆周等间隔。当加强构件在较大直径上膨胀时，梁之间的备用空间围绕插管的圆周保持等间隔。用于加强构件的该设计提供了梁之间的空间，其中优选形状，尺寸和取向的孔可通过套管放置，而不需要切割加强构件的材料。

140. 发明授权

US5676653A Kink-resistant steerable catheter assembly 失效
标题翻译：抗扭转导管组件
公开(公告)号：US5676653A
公开(公告)日：1997-10-14
申请号：US619912
申请日：1996-03-20
申请人： Kevin Taylor , Philip F. Latzgo , Timothy J. Lenihan
发明人： Kevin Taylor , Philip F. Latzgo , Timothy J. Lenihan
IPC分类号： A61M25/00 , A61M25/01 , A61M25/092 , A61M37/00
CPC分类号： A61M25/0144 , A61M25/0147 , A61M2025/0036 , A61M2025/0037 , A61M2025/004 , A61M2025/015 , A61M25/0032 , A61M25/0074 , A61M25/008 , A61M25/0082
摘要： A kink-resistant steerable catheter assembly suitable for microwave ablation includes a handle, a catheter and a steering control. The catheter has (a) a flexible, torque-transmitting and axially incompressible proximal or body portion terminating in a proximal end attached to the handle, and (b) a flexible and axially compressible distal or tip portion terminating in a distal end. A coaxial cable is disposed in and extends through a large aperture in the catheter proximal portion, and a coaxial cable extension is generally centrally disposed in, substantially fills, and snugly extends through a large lumen in the catheter distal portion to reduce kinking. The control is disposed in and actuatable from the handle, for placing tension on one of a pair of steering wires while relaxing tension on the other of the pair of steering wires, thereby to bend the distal end of the coaxial cable extension toward the tensed one of the steering wires.
摘要翻译：适用于微波消融的抗扭转导管组件包括手柄，导管和转向控制装置。导管具有（a）柔性的，扭矩传递的和轴向不可压缩的近端或主体部分，其终止于附接到手柄的近端，以及（b）终止于远端的柔性且可轴向压缩的远端或尖端部分。同轴电缆设置在导管近端部分中并穿过导管近端部分中的大孔，并且同轴电缆延伸部通常居中设置在基本上填充并且紧密地延伸穿过导管远端部分中的大腔，以减少扭结。控制装置设置在手柄中并可从手柄驱动，用于在一对操纵线之一上张紧张力，同时放松一对转向线中的另一个上的张力，从而使同轴电缆延伸部的远端朝向张紧的一个的转向线。

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