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121. 发明授权

US07577479B2 Methods and devices for implementing time of day pacing adjustments 有权
标题翻译：实施时间调节的方法和设备
公开(公告)号：US07577479B2
公开(公告)日：2009-08-18
申请号：US11083136
申请日：2005-03-17
申请人： Jesse W. Hartley , Kent Lee , Quan Ni , Michael A. Querimit , Kenneth L. Baker , Ankur Garg , Kenneth I. Tobacman , Corey J. Miklos
发明人： Jesse W. Hartley , Kent Lee , Quan Ni , Michael A. Querimit , Kenneth L. Baker , Ankur Garg , Kenneth I. Tobacman , Corey J. Miklos
IPC分类号： A61N1/365
CPC分类号： A61B5/4812 , A61B5/4815 , A61N1/368 , A61N1/3688 , G06F19/00
摘要： Methods and systems are directed to delivering cardiac pacing therapy to a patient. A pacing therapy associated with one or more pacing parameters is delivered. Alternate cardiac pacing therapies associated with one or more alternate pacing parameters are transitioned to, based on a sleep/wake cycle of the patient. Interactions between the pacing parameters of the pacing therapy and the alternate pacing parameters are resolved. Resolving pacing parameters may be based on analysis of lower rate limits and/or lower rate hysteresis.
摘要翻译：方法和系统旨在向患者输送心脏起搏治疗。提供与一个或多个起搏参数相关的起搏疗法。与一个或多个替代起搏参数相关联的替代心脏起搏疗法基于患者的睡眠/唤醒周期而被转换。起搏治疗起搏参数与替代起搏参数之间的相互作用得到解决。分析起搏参数可以基于较低速率限制和/或较低速率滞后的分析。

122. 发明申请

US20090177702A1 Medical Event Logbook System and Method 有权
标题翻译：医疗事故日志系统与方法
公开(公告)号：US20090177702A1
公开(公告)日：2009-07-09
申请号：US12403880
申请日：2009-03-13
申请人： Jeffrey E. Stahmann , John D. Hatlestad , Jesse W. Hartley , Quan Ni , Kent Lee
发明人： Jeffrey E. Stahmann , John D. Hatlestad , Jesse W. Hartley , Quan Ni , Kent Lee
IPC分类号： G06F17/30 , G06F3/048
CPC分类号： A61B5/0803 , A61B5/02405 , A61N1/3601
摘要： An event-based approach to collecting and organizing information associated with events affecting respiration is presented. The detection or prediction of an event affecting the respiration of a patient initiates acquisition of information associated with the event. The respiratory logbook system acquires information associated with the event during the event and during intervals proximate in time to the event. The information is organized as a respiratory log entry. The user can access the information by operating a user interface. The information may be presented in textual or graphical form.
摘要翻译：提出了一种基于事件的方法来收集和组织与影响呼吸的事件相关的信息。影响患者呼吸的事件的检测或预测启动与事件相关联的信息的获取。呼吸记录系统在事件期间以及在时间上接近事件的间隔期间获取与事件相关联的信息。信息被组织为呼吸日志条目。用户可以通过操作用户界面访问信息。信息可以以文本或图形形式呈现。

123. 发明授权

US07510531B2 System and method for discrimination of central and obstructive disordered breathing events 有权
标题翻译：用于区分中枢性和阻塞性无序呼吸事件的系统和方法
公开(公告)号：US07510531B2
公开(公告)日：2009-03-31
申请号：US10824776
申请日：2004-04-15
申请人： Kent Lee , John D. Hatlestad , Qingsheng Zhu , Jeffrey E. Stahmann , Jesse W. Hartley , Quan Ni
发明人： Kent Lee , John D. Hatlestad , Qingsheng Zhu , Jeffrey E. Stahmann , Jesse W. Hartley , Quan Ni
IPC分类号： A61B5/08
CPC分类号： A61B5/7264 , A61B5/0031 , A61B5/0205 , A61B5/0476 , A61B5/0478 , A61B5/0488 , A61B5/0496 , A61B5/08 , A61B5/0809 , A61B5/11 , A61B5/113 , A61B5/1135 , A61B5/4818
摘要： Disordered breathing events may be classified as central, obstructive or a combination of central an obstructive in origin based on patient motion associated with respiratory effort. Central disordered breathing is associated with disrupted respiration with reduced respiratory effort. Obstructive disordered breathing is associated with disrupted respiration accompanied by respiratory effort. A disordered breathing classification system includes a disordered breathing detector and a respiratory effort motion sensor. Components of the disordered breathing classification system may be fully or partially implantable.
摘要翻译：基于与呼吸努力相关的患者运动，无序呼吸事件可被分类为中枢性，阻塞性或中枢性阻塞性组合。呼吸中枢紊乱与呼吸力下降相关联。阻塞性无序呼吸与伴随呼吸功能的呼吸中断有关。无序呼吸分类系统包括无序呼吸检测器和呼吸力运动传感器。无序呼吸分类系统的组成部分可以完全或部分植入。

124. 发明授权

US07477932B2 Cardiac waveform template creation, maintenance and use 有权
标题翻译：心脏波形模板创建，维护和使用
公开(公告)号：US07477932B2
公开(公告)日：2009-01-13
申请号：US10448260
申请日：2003-05-28
申请人： Kent Lee , Rob Sweeney
发明人： Kent Lee , Rob Sweeney
IPC分类号： A61B5/0452
CPC分类号： A61B5/04525 , A61B5/7264
摘要： The present disclosure describes methods and systems for creating, adjusting, and using cardiac waveform morphology templates. The morphology templates include target regions associated with features of cardiac waveforms. The target regions may be adjusted based on relationships between the target regions and features of detected cardiac waveforms associated with the target regions. The templates may be used to analyze cardiac waveforms to classify or monitor various waveform morphologies. Templates may be created or eliminated based on a frequency of use. According to one approach, template creation involves providing target regions defined by one or more characteristics. The target regions are adjusted based on detected cardiac waveform features having similar characteristics. A template may be created using the target regions adjusted by this process.
摘要翻译：本公开描述了用于创建，调整和使用心脏波形形态学模板的方法和系统。形态学模板包括与心脏波形特征相关的目标区域。可以基于目标区域与与目标区域相关联的检测到的心脏波形的特征之间的关系来调整目标区域。模板可用于分析心脏波形以分类或监测各种波形形态。可以根据使用频率创建或删除模板。根据一种方法，模板创建涉及提供由一个或多个特征定义的目标区域。基于检测到的具有相似特征的心脏波形特征来调整目标区域。可以使用由此过程调整的目标区域来创建模板。

125. 发明申请

US20080312548A1 Methods and systems for implantably monitoring external breathing therapy 有权
公开(公告)号：US20080312548A1
公开(公告)日：2008-12-18
申请号：US12218409
申请日：2008-07-15
申请人： Jesse W. Hartley , Quan Ni , Jeffrey E. Stahmann , Kent Lee
发明人： Jesse W. Hartley , Quan Ni , Jeffrey E. Stahmann , Kent Lee
IPC分类号： A61B5/08
CPC分类号： A61B5/0538 , A61B5/0031 , A61B5/0809 , A61B5/4812 , A61B5/4815 , A61B5/4818 , A61M16/0051 , A61M16/026 , A61M2205/3523 , A61M2205/52 , A61M2230/00 , A61M2230/04 , A61M2230/18 , A61M2230/30 , A61M2230/40 , A61M2230/50 , A61M2230/60 , A61M2230/63 , A61M2230/65 , A61N1/368 , A61N1/3684
摘要： An implantable device is used to monitor one or more conditions associated with an external breathing therapy delivered to the patient. The device may monitor therapy parameters including therapy effectiveness, impact of the therapy on the patient, therapy usage, compliance with a prescribed usage, therapy interactions, and/or other parameters.

126. 发明申请

US20080294060A1 DEVICES AND METHODS FOR DISEASE DETECTION, MONITORING AND/OR MANAGEMENT 审中-公开
标题翻译：疾病检测，监测和/或管理的设备和方法
公开(公告)号：US20080294060A1
公开(公告)日：2008-11-27
申请号：US11751111
申请日：2007-05-21
申请人： Carlos F. Haro , Kent Lee , Kenneth C. Beck , Yi Zhang , Jeffrey E. Stahmann
发明人： Carlos F. Haro , Kent Lee , Kenneth C. Beck , Yi Zhang , Jeffrey E. Stahmann
IPC分类号： A61B5/087
CPC分类号： A61B5/087 , A61B5/03 , A61B5/0535 , A61B5/0809 , A61B5/6846
摘要： Embodiments of the invention are related to methods and devices for respiratory or cardiac disease detection, monitoring, and/or management. In an embodiment, the invention includes a method of calculating a pulmonary function parameter of a subject. The method can include obtaining a first signal indicative of lung volume change during breathing from a first sensor, obtaining a second signal indicative of distending pressure from a second sensor, and calculating the pulmonary function parameter based on the first signal and the second signal. In an embodiment, the invention includes a method of monitoring pulmonary or cardiac disease status. In an embodiment, the invention includes an implantable medical device. The implantable medical device can include a first sensor configured to produce a first signal indicative of lung volume change during breathing, a second sensor configured to produce a second signal indicative of intrapleural pressure, and a processor configured to calculate lung compliance or pulmonary resistance based on the first signal and the second signal. Other aspects and embodiments are provided herein.
摘要翻译：本发明的实施例涉及用于呼吸或心脏疾病检测，监测和/或管理的方法和装置。在一个实施例中，本发明包括计算受试者的肺功能参数的方法。该方法可以包括获得指示来自第一传感器的呼吸期间的肺体积变化的第一信号，获得表示来自第二传感器的膨胀压力的第二信号，以及基于第一信号和第二信号计算肺功能参数。在一个实施方案中，本发明包括监测肺或心脏疾病状态的方法。在一个实施例中，本发明包括可植入医疗装置。可植入医疗装置可以包括第一传感器，其被配置为产生指示呼吸期间肺体积变化的第一信号，配置成产生指示胸膜内压力的第二信号的第二传感器，以及被配置为基于以下步骤计算肺顺应性或肺阻力的处理器：第一信号和第二信号。本文提供了其它方面和实施例。

127. 发明申请

US20080139948A1 Use of external respiratory therapy device to detect cardiac electrical activity 有权
公开(公告)号：US20080139948A1
公开(公告)日：2008-06-12
申请号：US12069989
申请日：2008-02-14
申请人： Jeffrey E. Stahmann , Jesse W. Hartley , Kent Lee , Quan Ni
发明人： Jeffrey E. Stahmann , Jesse W. Hartley , Kent Lee , Quan Ni
IPC分类号： A61B5/0205
CPC分类号： A61B5/02405 , A61B5/0031 , A61B5/02055 , A61B5/0215 , A61B5/0421 , A61B5/0422 , A61B5/0464 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/053 , A61B5/0809 , A61B5/0836 , A61B5/087 , A61B5/103 , A61B5/1116 , A61B5/113 , A61B5/4818 , A61B5/6803 , A61B5/6823 , A61B5/686 , A61B2562/0219 , A61M16/0051 , A61M16/024 , A61M16/10 , A61M2016/0021 , A61M2016/0039 , A61M2016/0042 , A61M2205/3561 , A61M2205/3592 , A61M2230/04 , A61M2230/10 , A61M2230/432 , A61M2230/435 , A61M2230/60 , A61M2230/63 , A61M2230/65 , A61N1/362 , A61N1/3627 , A61N1/36514 , A61N1/36592 , A61N1/37
摘要： Methods and systems provide an integrated approach to respiratory and cardiac monitoring, diagnosis and/or therapy. A medical system includes one or more cardiac electrodes coupled to an external respiratory therapy device. The cardiac electrodes sense cardiac electrical activity that is used to generate an electrocardiogram (ECG) signal. Cardiac events, such as arrhythmia, myocardial infarction and/or ischemia, may be detected based on the sensed cardiac electrical activity.

128. 发明申请

US20080114219A1 MONITORING OF CHRONOBIOLOGICAL RHYTHMS FOR DISEASE AND DRUG MANAGEMENT USING ONE OR MORE IMPLANTABLE DEVICE 有权
标题翻译：使用一个或多个可植入装置监测疾病和药物管理的血液生殖系统
公开(公告)号：US20080114219A1
公开(公告)日：2008-05-15
申请号：US11554986
申请日：2006-10-31
申请人： Yi Zhang , John D. Hatlestad , Gerrard M. Carlson , Yousufali Dalal , Marina V. Brockway , Kent Lee , Richard O. Kuenzler , Carlos Haro , Krzysztof Z. Siejko , Abhilash Patangay
发明人： Yi Zhang , John D. Hatlestad , Gerrard M. Carlson , Yousufali Dalal , Marina V. Brockway , Kent Lee , Richard O. Kuenzler , Carlos Haro , Krzysztof Z. Siejko , Abhilash Patangay
IPC分类号： A61B5/00
CPC分类号： A61M5/1723 , A61B5/02055 , A61B5/0215 , A61B5/024 , A61B5/02405 , A61B5/053 , A61B5/0816 , A61B5/1116 , A61B5/686 , A61B5/7275 , A61N1/36114 , A61N1/36135 , A61N1/3621 , A61N1/365 , A61N1/36585 , G06F19/00
摘要： The health state of a subject is automatically evaluated or predicted using at least one implantable device. In varying examples, the health state is determined by sensing or receiving information about at least one physiological process having a circadian rhythm whose presence, absence, or baseline change is associated with impending disease, and comparing such rhythm to baseline circadian rhythm prediction criteria. Other chronobiological rhythms beside circadian may also be used. The baseline prediction criteria may be derived using one or more past physiological process observation of the subject or population of subjects in a non-disease health state. The prediction processing may be performed by the at least one implantable device or by an external device in communication with the implantable device. Systems and methods for invoking a therapy in response to the health state, such as to prevent or minimize the consequences of predicted impending heart failure, are also discussed.
摘要翻译：使用至少一个可植入装置自动评价或预测受试者的健康状况。在不同的实施例中，通过感测或接收关于至少一个具有昼夜节律的生理过程的信息来确定健康状况，所述生理过程的存在，不存在或基线变化与即将发生的疾病相关联，并将该节律与基线昼夜节律预测标准进行比较。也可以使用昼夜节律以外的其他时间生理节律。可以使用在非疾病健康状态下的受试者或受试者群体的一个或多个过去的生理过程观察来导出基线预测标准。预测处理可以由至少一个可植入装置或与可植入装置通信的外部装置执行。还讨论了响应于健康状态调用疗法的系统和方法，例如预防或最小化预期的即将到来的心力衰竭的后果。

129. 发明申请

US20080072003A1 METHOD AND APPARATUS FOR MASTER VOLUME ACCESS DURING COLUME COPY 有权
标题翻译：在大学复制期间主体积访问的方法和装置
公开(公告)号：US20080072003A1
公开(公告)日：2008-03-20
申请号：US11945940
申请日：2007-11-27
申请人： Ngoclan Vu , James Wayda , Kent Lee , Raghavendra Kulkarni
发明人： Ngoclan Vu , James Wayda , Kent Lee , Raghavendra Kulkarni
IPC分类号： G06F12/16
CPC分类号： G06F3/0617 , G06F3/065 , G06F3/067 , G06F11/1446 , G06F2201/84
摘要： A method and device for performing a volume copy is provided. The volume copy method allows access to both the Volume Copy Source and Volume Copy Target while the volume copy process is occurring. This allows a system administrator to initiate a volume copy without worrying that host access to the Volume Copy Source and Volume Copy Target will be interrupted.
摘要翻译：提供了用于执行卷拷贝的方法和设备。卷复制方法允许在卷复制过程发生时访问卷复制源和卷复制目标。这允许系统管理员启动卷拷贝，而不必担心主机对Volume Copy Source和Volume Copy Target的访问将被中断。

130. 发明申请

US20070185973A1 PULL DATA REPLICATION MODEL 有权
标题翻译：数据复制模型
公开(公告)号：US20070185973A1
公开(公告)日：2007-08-09
申请号：US11561680
申请日：2006-11-20
申请人： James George Wayda , Kent Lee , Elizabeth G. Rodriguez
发明人： James George Wayda , Kent Lee , Elizabeth G. Rodriguez
IPC分类号： G06F15/16
CPC分类号： H04L67/1095 , G06F3/0607 , G06F3/065 , G06F3/0659 , G06F3/067 , G06F11/1662 , H04L69/24
摘要： A data storage system, device, and method are provided for replicating data between different data storage systems or appliances. More specifically, the present invention allows an initiating data storage device to pull data from a target data storage device. Thus, the storage device that is supplying the data can act as a target and does not require the additional software inherent in being an initiator.
摘要翻译：提供了一种用于在不同数据存储系统或设备之间复制数据的数据存储系统，设备和方法。更具体地，本发明允许启动数据存储设备从目标数据存储设备拉取数据。因此，提供数据的存储设备可以充当目标，并且不需要作为发起者固有的附加软件。

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