专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

101. 发明申请

US20090298086A1 PLANT FARNESYLTRANSFERASES 失效
标题翻译：植物种子植物
公开(公告)号：US20090298086A1
公开(公告)日：2009-12-03
申请号：US12536203
申请日：2009-08-05
申请人： REBECCA E. CAHOON , Timothy George Helentjaris , Guo-Hua Miao
发明人： REBECCA E. CAHOON , Timothy George Helentjaris , Guo-Hua Miao
IPC分类号： C12Q1/68 , C12N15/11 , C12N1/19 , C12N1/21 , C12N5/04 , C12N7/00 , C12N15/87 , C12N9/10 , C12P19/34 , C40B30/04
CPC分类号： C12Q1/6811 , C12N9/1085 , C12N15/8243 , C12N15/8261 , C12N15/8273 , C12Y205/01021 , Y02A40/146
摘要： This invention relates to an isolated nucleic acid fragment encoding a farnesyltransferase subunit. The invention also relates to the construction of a chimeric gene encoding all or a portion of the farnesyltransferase subunit, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the farnesyltransferase subunit in a transformed host cell.
摘要翻译：本发明涉及编码法呢基转移酶亚单位的分离的核酸片段。本发明还涉及在正义或反义方向上构建编码全部或部分法呢基转移酶亚单位的嵌合基因，其中嵌合基因的表达导致转化的宿主细胞中法呢基转移酶亚单位的改变水平的产生。

102. 发明申请

US20090227013A1 Early Endosperm Promoter eep2 失效
标题翻译：早期胚乳启动子eep2
公开(公告)号：US20090227013A1
公开(公告)日：2009-09-10
申请号：US12463450
申请日：2009-05-11
申请人： Timothy G. Helentjaris , Xiaomu Niu
发明人： Timothy G. Helentjaris , Xiaomu Niu
IPC分类号： C12N15/82 , C07H21/04
CPC分类号： C12N15/8234 , C12N9/0032 , C12N9/1085 , C12N15/8243 , C12N15/8261 , C12N15/8271 , C12N15/8295 , Y02A40/146
摘要： This invention relates generally to the field of plant molecular biology. More specifically, this invention relates to methods and reagents for the temporally- and/or spatially-regulated expression of genes, particularly in plant seeds and related female reproductive tissue. Compositions comprise novel nucleotide sequences for a seed-preferred promoter known as eep2. A method for expressing a heterologous nucleotide sequence in a plant using the promoter sequences disclosed herein is provided. The method comprises transforming a plant cell to comprise a heterologous nucleotide sequence operably linked to one of the promoters of the present invention and regenerating a stably transformed plant from the transformed plant cell.
摘要翻译：本发明一般涉及植物分子生物学领域。更具体地，本发明涉及用于时间和/或空间调节基因表达的方法和试剂，特别是在植物种子和相关的雌性生殖组织中。组合物包含称为eep2的种子优选启动子的新型核苷酸序列。提供了使用本文公开的启动子序列在植物中表达异源核苷酸序列的方法。该方法包括转化植物细胞以包含与本发明的启动子之一可操作地连接的异源核苷酸序列，并从转化的植物细胞再生稳定转化的植物。

103. 发明申请

US20090007301A1 Plant Promoters, Terminators, Genes, Vectors and Related Transformed Plants 审中-公开
标题翻译：植物启动子，终止子，基因，载体和相关转化植物
公开(公告)号：US20090007301A1
公开(公告)日：2009-01-01
申请号：US11918032
申请日：2006-04-17
申请人： Hsu-Ching Chen Wintz , Ebrahim Firoozabady
发明人： Hsu-Ching Chen Wintz , Ebrahim Firoozabady
IPC分类号： C12N15/11 , A01H5/00 , C12N15/82
CPC分类号： C12N9/90 , C12N9/0004 , C12N9/1085 , C12N9/88 , C12N15/8216
摘要： The invention provides novel regulatory polynucleotide sequences useful in plant genetic engineering applications, e.g., polynucleotides having transcriptional promoter or terminator activity, are provided. The invention also provides novel gene and polypeptide sequences, for example, genes corresponding to pineapple carotenoid biosynthesis proteins, e.g., carotenoid isomerase (ISO), phytoene synthase (PSY) and lycopene β-cyclase (LYC), which find use in producing plants with improved traits, e.g., improved nutritional value. In addition, related nucleic acids, e.g., vectors, and transformed plants that include one or more of these polynucleotides or polypeptides are also provided, as are related methods for producing such compositions.
摘要翻译：本发明提供了可用于植物遗传工程应用的新型调控多核苷酸序列，例如具有转录启动子或终止子活性的多核苷酸。本发明还提供新的基因和多肽序列，例如对应于菠萝类胡萝卜素生物合成蛋白质的基因，例如类胡萝卜素异构酶（ISO），番茄红素合成酶（PSY）和番茄红素β-环化酶（LYC），其用于产生具有改善的特征，例如改善营养价值。此外，还提供了包括这些多核苷酸或多肽中的一种或多种的相关核酸，例如载体和转化植物，以及用于制备这种组合物的相关方法。

104. 发明申请

US20080274478A1 NOVEL AROMATIC PRENYLTRANSFERASES, NUCLEIC ACIDS ENCODING SAME AND USES THEREFOR 有权
标题翻译：新型芳香丙烯酸酯，编码其的核酸及其用途
公开(公告)号：US20080274478A1
公开(公告)日：2008-11-06
申请号：US12106181
申请日：2008-04-18
申请人： Tomohisa Kuzuyama , Joseph P. Noel , Stephane P. Richard
发明人： Tomohisa Kuzuyama , Joseph P. Noel , Stephane P. Richard
IPC分类号： G01N33/573 , C12N9/10 , C12P1/00
CPC分类号： C12N9/1085
摘要： In accordance with the present invention, a novel aromatic prenyltransferase, Orf2 from Streptomyces sp. strain CL190, involved in naphterpin biosynthesis has been identified and the structure thereof elucidated. This prenyltransferase catalyzes the formation of a C—C bond between a prenyl group and a compound containing an aromatic nucleus, and also displays C—O bond formation activity. Numerous crystallographic structures of the prenyltransferase have been solved and refined, e.g., (1) prenyltransferase complexed with a buffer molecule (TAPS), (2) prenyltransferase as a binary complex with geranyl diphosphate (GPP) and Mg2+, and prenyltransferase as ternary complexes with a non-hydrolyzable substrate analogue, geranyl S-thiolodiphosphate (GSPP) and either (3) 1,6-dihydroxynaphthalene (1,6-DHN), or (4) flaviolin (i.e., 2,5,7-trihydroxy-1,4-naphthoquinone, which is the oxidized product of 1,3,6,8-tetrahydroxynaphthalene (THN)). These structures have been solved and refined to 1.5 Å, 2.25 Å, 1.95 Å and 2.02 Å, respectively. This first structure of an aromatic prenyltransferase displays an unexpected and non-canonical (β/α)-barrel architecture. The complexes with both aromatic substrates and prenyl containing substrates and analogs delineate the active site and are consistent with a proposed electrophilic mechanism of prenyl group transfer. These structures also provide a mechanistic basis for understanding prenyl chain length determination and aromatic co-substrate recognition in this structurally unique family of aromatic prenyltransferases. This structural information is useful for predicting the aromatic prenyltransferase activity of proteins.
摘要翻译：根据本发明，一种新型芳族异戊烯基转移酶，来自链霉菌属的Orf2。已经鉴定了参与萘普生生物合成的菌株CL190，其结构被阐明。该异戊烯基转移酶催化异戊烯基和含有芳香核的化合物之间的C-C键的形成，并且还显示C-O键的形成活性。已经解决和改进了异戊烯基转移酶的许多晶体结构，例如（1）与缓冲分子（TAPS）复合的异戊烯基转移酶，（2）作为二进位配合物的异戊烯基转移酶与香叶基二磷酸酯（GPP）和Mg 2+ （3）1,6-二羟基萘（1,6-DHN）或（4）黄堇素（即2号）的三钠配合物，，5,7-三羟基-1,4-萘醌，其为1,3,6,8-四羟基萘（THN）的氧化产物）。这些结构分别被解析和精炼成1.5A，2.25，1.95和2.02。芳族异戊烯基转移酶的这种第一结构显示出意想不到的和非规范（β/α） - 杆状结构。具有芳香底物和含异戊烯基的底物和类似物的络合物描绘了活性位点，并与提出的异戊烯基转移的亲电子机制一致。这些结构还提供了在这个结构独特的芳族异戊烯基转移酶家族中了解异戊烯基链长度测定和芳香族共底物识别的机理基础。该结构信息对于预测蛋白质的芳族异戊烯基转移酶活性是有用的。

105. 发明授权

US07446242B2 Plants with improved morphogenesis and method of constructing the same 失效
标题翻译：具有改良形态发生的植物及其构建方法
公开(公告)号：US07446242B2
公开(公告)日：2008-11-04
申请号：US10926450
申请日：2004-08-26
申请人： Yoshihisa Kasukabe , Izumi Ihara , Shoji Tachibana , Keisuke Matsui , Masako Mizutani
发明人： Yoshihisa Kasukabe , Izumi Ihara , Shoji Tachibana , Keisuke Matsui , Masako Mizutani
IPC分类号： C12N15/82
CPC分类号： C12N9/1085 , C07K14/415 , C12N9/88 , C12N15/8243
摘要： The invention relates to plants and their progeny with improved morphogenesis in a variety of organs; to a method for producing the plants; and to a method for producing calli.
摘要翻译：本发明涉及在各种器官中具有改善的形态发生的植物及其后代; 涉及一种生产植物的方法; 以及一种生产愈伤组织的方法。

106. 发明申请

US20080233627A1 Nicotianamine synthase and gene encoding the same 失效
标题翻译：烟碱合成酶和基因编码相同
公开(公告)号：US20080233627A1
公开(公告)日：2008-09-25
申请号：US11702690
申请日：2007-02-05
申请人： Satoshi Mori , Kyoko Higuchi , Kazuya Suzuki , Naoko Nishizawa , Hiromi Nakanishi
发明人： Satoshi Mori , Kyoko Higuchi , Kazuya Suzuki , Naoko Nishizawa , Hiromi Nakanishi
IPC分类号： C12N9/88
CPC分类号： C12N9/1085 , C12N15/8243 , C12N15/8271
摘要： A nicotianamine synthase is isolated and purified. Then the gene of this enzyme is cloned and the base sequence and amino acid sequence thereof are determined. This gene is employed in constructing plants, in particular, grass plants highly tolerant to iron-deficiency. A nicotianamine synthase involved in the mugineic acid biosynthesis pathway; the amino acid sequence thereof; a gene encoding the same; a vector containing this gene; cells transformed by the vector; a process for producing nicotianamine by using the same; plants transformed by the gene encoding the nicotianamine synthase; and an antibody against the nicotianamine syntase.
摘要翻译：分离和纯化烟碱胺合酶。然后克隆该酶的基因，确定其碱基序列和氨基酸序列。该基因用于构建植物，特别是高度耐铁缺乏的草本植物。涉及木瓜酸生物合成途径的烟碱胺合酶; 其氨基酸序列; 编码该基因的基因; 含有该基因的载体; 由载体转化的细胞; 通过使用它来生产烟碱胺的方法; 由编码烟碱胺合成酶的基因转化的植物; 和针对烟碱胺合成酶的抗体。

107. 发明授权

US07422878B1 Process for microbial production of ubiquinone-10 using Rhodobacter 失效
标题翻译：使用红细菌的微生物生产泛醌-10的方法
公开(公告)号：US07422878B1
公开(公告)日：2008-09-09
申请号：US10110393
申请日：2000-10-13
申请人： Koichiro Miyake , Shin-ichi Hashimoto , Akio Ozaki
发明人： Koichiro Miyake , Shin-ichi Hashimoto , Akio Ozaki
IPC分类号： C12P7/66
CPC分类号： C12N9/1085 , A61K38/00 , C12N15/52 , C12P7/66
摘要： The present invention provides a process for producing ubiquinone-10 using a microorganism having the ability to form ubiquinone-10 and having one or more properties selected from the group consisting of the property wherein geranylgeranyltransferase activity is reduced or defective, the property wherein decaprenyldiphosphate synthetase activity is strengthened, and the property wherein p-hydroxybenzoic acid-decaprenyltransferase activity is strengthened, DNA and a polypeptide useful for the production process, microorganisms useful for the production, a method for expressing a gene in the microorganisms, and a method for breeding the microorganisms.
摘要翻译：本发明提供使用具有形成泛醌-10的能力的微生物生产泛醌-10的方法，并具有一种或多种选自以下的性质：其中er牛儿基ger酰基转移酶活性降低或缺陷，其中十聚十二烷基二磷酸合成酶活性并且其中对羟基苯甲酸 - 十 - 癸酰基转移酶活性增强的性质，可用于生产过程的DNA和多肽，可用于生产的微生物，在微生物中表达基因的方法以及用于培养微生物的方法。

108. 发明申请

US20080201796A1 Transformed plants accumulating mono-and/or sesquiterpenes 审中-公开
标题翻译：积累单和/或倍半萜的转化植物
公开(公告)号：US20080201796A1
公开(公告)日：2008-08-21
申请号：US11916272
申请日：2006-06-26
申请人： Joe Chappell , Shuiqin Wu , Michel Schalk , Athony Clark
发明人： Joe Chappell , Shuiqin Wu , Michel Schalk , Athony Clark
IPC分类号： A01H1/00 , A01H5/00 , C12N15/82 , C12N15/00
CPC分类号： C12N15/8243 , C12N9/0006 , C12N9/1085
摘要： The present invention relates to plant expressing transgenes and to plants transformed to comprise additional copies of genes, said genes encoding at least a HMGR-CoA reductase and a terpene synthase. The invention further claims methods for preparing the plants, and a method for producing terpenes. The present thus provides a reliable and cost effective platform for generating any terpene, in particular any mono- and/or sesquiterpene of interest. For example, the skilled person may use any gene encoding a sesquiterpene synthase for accumulating the respective sesquiterpene in the plant of the present invention.
摘要翻译：本发明涉及表达转基因的植物和转化成包含编码另外的基因拷贝的植物，所述基因编码至少HMGR-CoA还原酶和萜烯合酶。本发明进一步要求制备植物的方法以及萜烯的制备方法。因此，本发明提供了用于产生任何萜烯，特别是感兴趣的任何单 - 和/或倍半萜的可靠和具有成本效益的平台。例如，技术人员可以使用编码倍半萜合酶的任何基因来在本发明的植物中积累相应的倍半萜烯。

109. 发明申请

US20080199920A1 S-Adenosylmethionine-6-N-Lysine-Methyltransferase From Neurospora Crassa, A Gene Encoding The Same, A Vector And Host Cell Containing The Same, And Method For Producing Trimethyllysine Using The Host Cell 有权
标题翻译：来自粗糙脉孢菌的S-腺苷甲硫氨酸-6-N-赖氨酸 - 甲基转移酶，编码它的基因，含有它的载体和宿主细胞以及使用宿主细胞产生三甲基赖氨酸的方法
公开(公告)号：US20080199920A1
公开(公告)日：2008-08-21
申请号：US11994938
申请日：2006-07-07
申请人： Whan-Koo Kang , Bheong-Uk Lee , Young-Hoon Park , Eun-Sung Koh , Jae-Yeong Ju , Jin-Ho Lee , Hye-Won Kim , Hye-Jin Choi
发明人： Whan-Koo Kang , Bheong-Uk Lee , Young-Hoon Park , Eun-Sung Koh , Jae-Yeong Ju , Jin-Ho Lee , Hye-Won Kim , Hye-Jin Choi
IPC分类号： C12P13/08 , C12N9/10 , C07H21/04 , C12N15/00 , C12N1/20
CPC分类号： C12P13/08 , C12N9/1085
摘要： Provided is S-adenosylmethionine-6-N-lysine-methyl-transferase obtained from Neνrospora crassa, a polynucleotide encoding the same, a vector and host cell containing the polynucleotide, and a method of producing trimethyllysine by culturing the host cell.
摘要翻译：本发明提供从粗核粗核菌（Nenurospora crassa）获得的S-腺苷甲硫氨酸-6-N-赖氨酸甲基转移酶，其编码该多核苷酸的多核苷酸，含有多核苷酸的载体和宿主细胞，以及通过培养宿主细胞产生三甲基赖氨酸的方法。

110. 发明申请

US20080171378A1 Genetically Modified Host Cells And Use Of Same For Producing Isoprenoid Compounds 有权
标题翻译：遗传修饰宿主细胞及其生产异戊二烯类化合物的用途
公开(公告)号：US20080171378A1
公开(公告)日：2008-07-17
申请号：US11571315
申请日：2005-07-21
申请人： Jay D. Keasling , James Kirby , Eric M. Paradise
发明人： Jay D. Keasling , James Kirby , Eric M. Paradise
IPC分类号： C12N1/00
CPC分类号： C12P5/007 , C12N9/0006 , C12N9/1085 , C12N9/88 , C12N15/81 , C12P23/00 , C12Y101/01034 , C12Y205/01092 , C12Y402/03024
摘要： The present invention provides genetically modified eukaryotic host cells that produce isoprenoid precursors or isoprenoid compounds. A subject genetically modified host cell comprises increased activity levels of one or more of mevalonate pathway enzymes, increased levels of prenyltransferase activity, and decreased levels of squalene synthase activity. Methods are provided for the production of an isoprenoid compound or an isoprenoid precursor in a subject genetically modified eukaryotic host cell. The methods generally involve culturing a subject genetically modified host cell under conditions that promote production of high levels of an isoprenoid or isoprenoid precursor compound.
摘要翻译：本发明提供了产生类异戊二烯前体或类异戊二烯化合物的遗传修饰的真核宿主细胞。受试者遗传修饰的宿主细胞包括增加一种或多种甲羟戊酸途径酶的活性水平，异丙烯基转移酶活性水平升高和角鲨烯合酶活性水平降低。提供了用于在受试者遗传修饰的真核宿主细胞中产生类异戊二烯化合物或类异戊二烯前体的方法。所述方法通常涉及在促进产生高水平的类异戊二烯或类异戊二烯前体化合物的条件下培养受试者遗传修饰的宿主细胞。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式