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101. 发明申请

US20060111281A1 Cyclic peptide compositions for treatment of sexual dysfunction 有权
标题翻译：用于治疗性功能障碍的循环肽组合物
公开(公告)号：US20060111281A1
公开(公告)日：2006-05-25
申请号：US11269271
申请日：2005-11-09
申请人： Shubh Sharma , Wei Yang
发明人： Shubh Sharma , Wei Yang
IPC分类号： A61K38/12 , C07K7/64
CPC分类号： A61K38/12 , A61K31/519 , A61K31/565 , C07K7/56 , C07K14/665 , C07K14/685 , Y10S436/811 , A61K2300/00
摘要： A cyclic peptide of the structural formula: or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, m and p are as defined. Further provided are compositions for treatment of sexual dysfunction in mammals, including male sexual dysfunction, such as erectile dysfunction, and female sexual dysfunction, by administration of a cyclic peptide including a C-terminus —OH group. Routes of administration include injection, oral, urethral, vaginal, nasal and mucosal administration.
摘要翻译：结构式的环状肽或其药学上可接受的盐，其中R 1，R 2，R 3，R 3， R 5，R 5，R 6，m和p如上所定义。还提供了通过施用包括C末端-OH基团的环肽来治疗哺乳动物的性功能障碍的组合物，包括男性性功能障碍，例如勃起功能障碍和女性性功能障碍。给药途径包括注射，口服，尿道，阴道，鼻和粘膜给药。

102. 发明申请

US20060083685A1 Opioid metallopeptide compositions and methods 审中-公开
标题翻译：阿片类金属肽组合物和方法
公开(公告)号：US20060083685A1
公开(公告)日：2006-04-20
申请号：US11291389
申请日：2005-12-01
申请人： Shubh Sharma , Wei Yang , Hui-Zhi Cai
发明人： Shubh Sharma , Wei Yang , Hui-Zhi Cai
IPC分类号： A61K51/00 , C40B40/10 , C07K7/06
CPC分类号： C07K5/1027 , A61K51/0478 , C07K1/047 , C07K5/1008 , C07K5/1016
摘要： Metallopeptides and metallopeptide combinatorial libraries specific for opioid receptors are provided, for use in biological, pharmaceutical and related applications. The metallopeptides and combinatorial libraries are made of peptides, peptidomimetics and peptide-like constructs, in which the peptide, peptidomimetic or construct is conformationally fixed in a biologically active configuration specific for one or more opioid receptors on complexation of a metal ion-binding portion thereof with a metal ion.
摘要翻译：提供了特异于阿片受体的金属肽和金属肽组合文库，用于生物，药物和相关应用。金属肽和组合文库由肽，肽模拟物和肽样构建体制成，其中肽，拟肽或构建体在一种或多种阿片受体特异性的生物活性构型中被构象地固定在金属离子结合部分的络合物上与金属离子。

103. 发明申请

US20060063991A1 Method and apparatus for non-invasive measurement of blood analytes with dynamic spectral calibration 审中-公开
标题翻译：用动态光谱校准对血液分析物进行非侵入性测量的方法和装置
公开(公告)号：US20060063991A1
公开(公告)日：2006-03-23
申请号：US10914761
申请日：2004-08-09
申请人： Dejin Yu , Wei Yang
发明人： Dejin Yu , Wei Yang
IPC分类号： A61B5/00
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/6826 , A61B5/6838 , A61B5/702 , G01N21/65
摘要： The present invention discloses a method and apparatus and method for achieving non-invasive measurement of analytes from human and animal blood through the skin using Raman lightwave technology. The apparatus includes a confocal signal collection system that effectively reduces the interferences from out-of-focus signals. The apparatus further includes a tissue permeation unit, which controls the amount of blood in the laser tissue interaction region. The change of aggregate spectra with time is used to construct a new series of differenced spectra, from which the spectral effects from surrounding static substances are calibrated out dynamically using the data processing method described.
摘要翻译：本发明公开了一种使用拉曼光波技术从人体和动物血液通过皮肤非侵入性地测量分析物的方法和装置和方法。该装置包括共焦信号收集系统，其有效地减少了离焦信号的干扰。该装置还包括组织渗透单元，其控制激光组织相互作用区域中的血液量。聚合谱随时间的变化被用来构建一系列新的差分光谱，使用所描述的数据处理方法动态校正周围静态物质的光谱效应。

104. 发明申请

US20050164914A1 Metallopeptide compositions for treatment of sexual dysfunction 失效
标题翻译：用于治疗性功能障碍的金属肽组合物
公开(公告)号：US20050164914A1
公开(公告)日：2005-07-28
申请号：US11036273
申请日：2005-01-14
申请人： Shubh Sharma , Annette Shadiack , Wei Yang , Ramesh Rajpurohit
发明人： Shubh Sharma , Annette Shadiack , Wei Yang , Ramesh Rajpurohit
IPC分类号： A61K38/00 , A61K51/04 , A61K51/08 , C07K5/117 , C07K7/06 , C07K14/575 , C07K14/68 , A61K38/40 , A61K38/16
CPC分类号： C07K7/06 , A61K38/00 , A61K51/0497 , A61K2121/00 , A61K2123/00 , C07K5/1024 , C07K14/575 , C07K14/68
摘要： Metallopeptide compositions are provided for treatment of sexual dysfunction in mammals, including male sexual dysfunction, such as erectile dysfunction, and female sexual dysfunction. The metallopeptides include at least one, and preferably two, aromatic amino acid side chain moieties, and are further characterized in that the metallopeptides preferably do not bind or significantly bind to a melanocortin receptor.
摘要翻译：提供金属肽组合物用于治疗哺乳动物的性功能障碍，包括男性性功能障碍，如勃起功能障碍和女性性功能障碍。金属肽包括至少一个，优选两个芳族氨基酸侧链部分，其特征还在于金属肽优选不结合或显着结合黑皮质素受体。

105. 发明授权

US06248416B1 Highly oriented magnetic thin films, recording media, transducers, devices made therefrom and methods of making 失效
标题翻译：高取向磁性薄膜，记录介质，换能器，由其制成的装置和制造方法
公开(公告)号：US06248416B1
公开(公告)日：2001-06-19
申请号：US08967669
申请日：1997-11-10
申请人： David N. Lambeth , David E. Laughlin , Wei Yang , Heng Gong , Jie Ziou
发明人： David N. Lambeth , David E. Laughlin , Wei Yang , Heng Gong , Jie Ziou
IPC分类号： G11B566
CPC分类号： G11B5/667 , G11B5/7325 , Y10T428/12611 , Y10T428/265
摘要： The present invention provides for magnetic and magneto-optic recording media, transducers and data storage devices constructed therefrom that have highly oriented films having long range order in the crystal structure of the film. The recording medium includes a magnetic recording layer comprised of Co-based material, such as Co or one or more Co alloys having a (10{overscore (1)}0) crystal texture, a substrate, a first underlayer having a fcc structure and a (110) crystal texture disposed between the substrate and the magnetic recording layer. A second underlayer having a bcc structure and a (112) crystal texture is also disposed between the magnetic recording layer and the first underlayer. In particular, if a (110) Si single crystal substrate is non-oxidized certain metals having fcc structures, such as Ag, Cu, Al, and Au and fcc derivative structures, such L10 and L12 structures, can be epitaxially grown on the Si surface. While the one unit cell to one unit cell lattice match between fcc Ag and A4 (diamond) Si is quite poor, multiples of the Ag unit cell distance fit very well on the Si surface. The long range order of the Si surface induces the epitaxial growth of the Ag fcc structure. Upon this fcc structure, a bcc structure, such as Cr, or a bcc derivative, such as B2, DO3 and/or L21 can be epitaxially grown.
摘要翻译：本发明提供了由其构成的磁和磁光记录介质，换能器和数据存储装置，其具有在膜的晶体结构中具有长距离顺序的高取向膜。记录介质包括由Co基材料组成的磁记录层，例如Co或具有（10 {overscore（1）} O）晶体结构的一种或多种Co合金，衬底，具有fcc结构的第一底层和设置在基板和磁记录层之间的（110）晶体结构。具有bcc结构和（112）晶体结构的第二底层也设置在磁记录层和第一底层之间。特别地，如果（110）Si单晶衬底不被氧化，则可以在Si上外延生长具有fcc结构的某些金属，例如Ag，Cu，Al和Au以及fcc衍生结构，如L10和L12结构表面。虽然fcc Ag和A4（金刚石）Si之间的一个单元电池与一个单元电池晶格匹配相当差，但是Ag单元电池距离的倍数在Si表面上很好地匹配。 Si表面的长距离顺序引起Ag fcc结构的外延生长。在该fcc结构中，可以外延生长诸如Cr的bcc结构或bcc衍生物，例如B2，DO3和/或L21。

106. 发明授权

US06190037B1 Non-intrusive, on-the-fly (OTF) temperature measurement and monitoring system 有权
标题翻译：非侵入式（OTF）温度测量和监测系统
公开(公告)号：US06190037B1
公开(公告)日：2001-02-20
申请号：US09253220
申请日：1999-02-19
申请人： Ashok Das , Nety Krishna , Marc Schweitzer , Nalin Patadia , Wei Yang , Umesh Kelkar , Vijay Parkhe , Scot Petitt , Nitin Khurana
发明人： Ashok Das , Nety Krishna , Marc Schweitzer , Nalin Patadia , Wei Yang , Umesh Kelkar , Vijay Parkhe , Scot Petitt , Nitin Khurana
IPC分类号： G01J500
CPC分类号： G01J5/041 , G01J5/0022
摘要： The present invention provides an apparatus and method for measuring the temperature of a moving radiant object. A probe, such as a pyrometer, is disposed in an opening of a vacuum chamber adjacent a radiation transparent window. The probe defines an optical path which intercepts the radiant object entering or exiting a processing chamber. The radiant object is moved through the optical path and emits electromagnetic waves. The electromagnetic waves are collected by the probe and transmitted to a signal processing unit where the waves are detected and converted to a temperature reading. If desired, the accumulated data may then be used to generate a cooling curve representing the thermal effects experienced by the radiant object. Extrapolation or correlation methods may be used to extend the cooling curve to points in time prior to or after the data collected by the probe.
摘要翻译：本发明提供了一种用于测量运动辐射物体的温度的装置和方法。诸如高温计的探针设置在与辐射透明窗相邻的真空室的开口中。探针限定了拦截进入或离开处理室的辐射物体的光路。辐射物体通过光路移动并发射电磁波。电磁波由探头收集并传输到信号处理单元，在该信号处理单元检测波并将其转换为温度读数。如果需要，则可以使用累积的数据来产生表示辐射物体经历的热效应的冷却曲线。可以使用外推法或相关方法将冷却曲线延伸到由探针收集的数据之前或之后的时间点。

107. 发明授权

US09492698B2 Trampolines 有权
标题翻译：蹦床
公开(公告)号：US09492698B2
公开(公告)日：2016-11-15
申请号：US14124491
申请日：2012-06-07
申请人： Joe Andon , Wei Yang
发明人： Joe Andon , Wei Yang
IPC分类号： A63B21/00 , A63B5/11 , A63B71/02 , A63B21/02
CPC分类号： A63B5/11 , A63B21/026 , A63B71/02 , A63B71/022 , A63B2210/50
摘要： A trampoline including: a frame adapted to rest on the ground or be mounted on a plurality of spaced apart legs; a plurality of spaced apart flexible and resilient plates extending upwards from said frame and connected thereto against relative movement therebetween; and a jumping mat operatively connected to said plates above said frame for movement with said plates upon a person jumping thereon.
摘要翻译：一种蹦床，包括：适于搁置在地面上或安装在多个间隔开的腿上的框架; 多个间隔开的柔性和弹性板，其从所述框架向上延伸并与之相连，以抵抗它们之间的相对移动; 以及跳跃垫，其可操作地连接到所述框架上方的所述板，用于在人跳过其上时与所述板一起移动。

108. 发明授权

US09399152B2 Trampoline 有权
公开(公告)号：US09399152B2
公开(公告)日：2016-07-26
申请号：US14701889
申请日：2015-05-01
申请人： Wei Yang
发明人： Wei Yang
IPC分类号： A63B5/11 , A63B71/02 , F16B7/00
CPC分类号： A63B5/11 , A63B71/022 , F16B7/00 , F16B7/042
摘要： The present invention is a trampoline with a unique frame structure to improve strength, stability and safety. The safety poles of the trampoline are organized in a lattice type of formation with multiple joints. It provides more coverage around the trampoline as a safety mechanism. The lattice type formation also strengthens the safety poles via strategic connections, disperses force asserted onto the safety poles. As a result, the trampoline of the present invention guarantees a safe and stable amount of space for bouncing, suitable for children as well as for adults.

109. 发明授权

US09277679B2 Heat sink fin including angular dimples 有权
标题翻译：散热片包括角凹坑
公开(公告)号：US09277679B2
公开(公告)日：2016-03-01
申请号：US13207062
申请日：2011-08-10
申请人： Yuandong Gu , Wei Yang
发明人： Yuandong Gu , Wei Yang
IPC分类号： F28F7/00 , H05K7/20 , H01L21/48 , H01L23/367 , H01L23/467
CPC分类号： H05K7/20563 , H01L21/4878 , H01L21/4882 , H01L23/3672 , H01L23/467 , H01L2924/0002 , Y10T29/4935 , H01L2924/00
摘要： A heat sink fin that has a first substrate. The first substrate includes a first angular dimple and a first micro air channel in fluid communication with the first angular dimple. The first angular dimple includes a first surface that forms an angle relative to a first plane of the first substrate. The first angular dimple includes a first micro diameter hole in fluid communication with the first angular dimple. The heat sink fin also has a second substrate folded against the first substrate. The second substrate includes a second angular dimple and a second micro air channel in fluid communication with the second angular dimple. The second angular dimple includes a second surface that forms an angle relative to a second plane of the second substrate. The second angular dimple includes a second micro diameter hole in fluid communication with the second angular dimple.
摘要翻译：具有第一基板的散热片。第一衬底包括第一角凹坑和与第一角凹坑流体连通的第一微空气通道。第一角凹坑包括相对于第一基板的第一平面形成一角度的第一表面。第一角凹坑包括与第一角凹坑流体连通的第一微孔。散热鳍片还具有折叠在第一衬底上的第二衬底。第二基板包括与第二角凹坑流体连通的第二角凹坑和第二微空气通道。第二角凹坑包括相对于第二基板的第二平面形成一角度的第二表面。第二角凹坑包括与第二角凹坑流体连通的第二微孔。

110. 发明申请

US20160030794A1 Trampoline 审中-公开
标题翻译：蹦床
公开(公告)号：US20160030794A1
公开(公告)日：2016-02-04
申请号：US14701889
申请日：2015-05-01
申请人： Wei Yang
发明人： Wei Yang
IPC分类号： A63B5/11
CPC分类号： A63B5/11 , A63B71/022 , F16B7/00 , F16B7/042
摘要： The present invention is a trampoline with a unique frame structure to improve strength, stability and safety. The safety poles of the trampoline are organized in a lattice type of formation with multiple joints. It provides more coverage around the trampoline as a safety mechanism. The lattice type formation also strengthens the safety poles via strategic connections, disperses force asserted onto the safety poles. As a result, the trampoline of the present invention guarantees a safe and stable amount of space for bouncing, suitable for children as well as for adults.
摘要翻译：本发明是具有独特框架结构的蹦床，以提高强度，稳定性和安全性。蹦床的安全杆组织成具有多个接头的格子式地层。它作为安全机制提供了围绕蹦床的更多覆盖。格子形式还通过战略连接加强安全极，将力分散到安全极上。结果，本发明的蹦床保证适合儿童和成人的安全和稳定的弹跳空间。

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