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101. 发明申请

US20090157132A1 DEFIBRILLATION SHOCK OUTPUT CIRCUIT 有权
标题翻译：去颤动输出电路
公开(公告)号：US20090157132A1
公开(公告)日：2009-06-18
申请号：US12332497
申请日：2008-12-11
申请人： William J. Linder , Hari Sree
发明人： William J. Linder , Hari Sree
IPC分类号： A61N1/39
CPC分类号： A61N1/3918 , A61N1/36185 , A61N1/3686 , A61N1/3688
摘要： This document discusses, among other things, techniques for generating and delivering a high voltage defibrillation shock using an implantable cardiac rhythm management device. An output energy delivery bridge can be programmed to provide desired shock vectors or polarities. A bootstrapped fully solid-state switch control voltage generation circuit is described. Automatic polarity or vector reconfiguration embodiments are described, such as in response to an unsuccessful attempt to convert the heart to a normal rhythm.
摘要翻译：本文件尤其涉及使用可植入式心律管理装置产生和递送高压除颤电击的技术。输出能量输送桥可以被编程以提供期望的震动矢量或极性。描述了自举完全固态开关控制电压产生电路。描述了自动极性或向量重新配置实施例，例如响应于将心脏转换成正常节奏的不成功的尝试。

102. 发明申请

US20090156957A1 PAINLESS NON-STIMULATING LEAD IMPEDANCE MEASUREMENT 有权
标题翻译：无刺激性铅阻抗测量
公开(公告)号：US20090156957A1
公开(公告)日：2009-06-18
申请号：US12333062
申请日：2008-12-11
申请人： William J. Linder , Angela M. Muttonen
发明人： William J. Linder , Angela M. Muttonen
IPC分类号： A61B5/05
CPC分类号： A61N1/3925 , A61N1/3937 , A61N2001/083
摘要： This document discusses, among other things, an apparatus comprising, a plurality of electrodes configured to deliver defibrillation countershock energy to a subject, an impedance measurement circuit communicatively coupled to the electrodes and configured to measure the impedance between any two of the electrodes using a non-stimulating excitation signal, and a controller communicatively coupled to the impedance measurement circuit and configured to calculate the impedance of a shock vector, wherein the shock vector includes a first electrode and a second electrode electrically connected together, and a third electrode, and wherein the controller calculates the impedance using measured impedances between the three electrodes when none of them are electrically connected.
摘要翻译：本文件尤其讨论了一种装置，其包括多个电极，其被配置为向受试者传递去颤颤的反相能量;阻抗测量电路，其通信地耦合到所述电极，并被配置为使用非电极来测量任何两个电极之间的阻抗; - 激励激励信号，以及控制器，其通信地耦合到所述阻抗测量电路并且被配置为计算冲击矢量的阻抗，其中所述冲击矢量包括电连接在一起的第一电极和第二电极以及第三电极，并且其中控制器使用三个电极之间的测量阻抗计算阻抗，当它们都没有电连接时。

103. 发明授权

US07515955B2 Method and apparatus for adjusting cardiac event detection threshold based on dynamic noise estimation 有权
标题翻译：基于动态噪声估计调整心脏事件检测阈值的方法和装置
公开(公告)号：US07515955B2
公开(公告)日：2009-04-07
申请号：US11557318
申请日：2006-11-07
申请人： William J. Linder , Jeremy Maniak , Ron A. Balczewski
发明人： William J. Linder , Jeremy Maniak , Ron A. Balczewski
IPC分类号： A61B5/0402
CPC分类号： A61B5/04017 , A61N1/3704 , A61N1/3925 , A61N1/3962 , Y10S128/901
摘要： An implantable cardiac rhythm management (CRM) device includes a sensing and detection circuit that senses at least one cardiac signal and detects cardiac electrical events from the sensed cardiac signal using a detection threshold that is adjusted based on a dynamic noise estimation. The sensed cardiac signal is filtered to produce a filtered cardiac signal having a signal frequency band and a noise signal having a noise frequency band. The noise frequency band is substantially different from the signal frequency band. A dynamic noise floor is produced based on the noise signal and used as the minimum value for the detection threshold. A cardiac electrical is detected when the amplitude of the filtered cardiac signal exceeds the detection threshold.
摘要翻译：可植入心律管理（CRM）装置包括感测和检测电路，其感测至少一个心脏信号并且使用基于动态噪声估计调整的检测阈值从所感测的心脏信号检测心脏电气事件。所感测的心脏信号被滤波以产生具有信号频带的滤波心脏信号和具有噪声频带的噪声信号。噪声频带与信号频带基本不同。基于噪声信号产生动态底噪，并将其用作检测阈值的最小值。当过滤的心脏信号的幅度超过检测阈值时，检测心电。

104. 发明授权

US07110824B2 Adaptive telemetry system and method for an implantable medical device 有权
标题翻译：用于可植入医疗装置的自适应遥测系统和方法
公开(公告)号：US07110824B2
公开(公告)日：2006-09-19
申请号：US10638945
申请日：2003-08-11
申请人： Mark D. Amundson , William J. Linder , Karen M. Lent , Scott T. Mazar
发明人： Mark D. Amundson , William J. Linder , Karen M. Lent , Scott T. Mazar
IPC分类号： A61B5/07 , A61N1/08
CPC分类号： A61N1/37252 , Y10S128/903
摘要： A system and method for transmitting telemetry data from an implantable medical device to an external device. A connection-oriented protocol is used to transmit data at a higher data rate while a burst mode protocol is used to transmit data a lower data rate. The lower data rate may be used for remote communications where the received signal is of lower power.
摘要翻译：一种用于将遥测数据从可植入医疗装置传送到外部装置的系统和方法。以连接为导向的协议用于以更高的数据速率传输数据，而突发模式协议用于传输较低数据速率的数据。较低的数据速率可用于接收信号功率较低的远程通信。

105. 发明授权

US07060030B2 Two-hop telemetry interface for medical device 有权
公开(公告)号：US07060030B2
公开(公告)日：2006-06-13
申请号：US10041725
申请日：2002-01-08
申请人： Jeffrey A. Von Arx , Michael J. Lyden , William J. Linder , Scott T. Mazar , Allan T. Koshiol , Mark Gryzwa , Dorothy Nauman , Scott Hostine
发明人： Jeffrey A. Von Arx , Michael J. Lyden , William J. Linder , Scott T. Mazar , Allan T. Koshiol , Mark Gryzwa , Dorothy Nauman , Scott Hostine
IPC分类号： A61B5/00
CPC分类号： A61N1/08 , G08C2201/40
摘要： This document discusses a system that includes an intermediary telemetry interface device for communicating between a cardiac rhythm management system or other implantable medical device and a programmer or other remote device. One example provides an inductive near-field communication link between the telemetry interface and the implantable medical device, and a radio-frequency (RF) far-field communication link between the telemetry interface device and the remote device. The telemetry interface device provides data buffering. In another example, the telemetry interface device includes a data processing module for compressing and/or decompressing data, or for extracting information from data. Such information extraction may include obtaining heart rate, interval, and/or depolarization morphology information from an electrogram signal received from the implantable medical device.

106. 发明授权

US06662048B2 Implantable medical device with temperature measuring and storing capability 有权
公开(公告)号：US06662048B2
公开(公告)日：2003-12-09
申请号：US09823260
申请日：2001-03-30
申请人： Ron A. Balczewski , Jeffrey A. Von Arx , William J. Linder , Mark D. Amundson
发明人： Ron A. Balczewski , Jeffrey A. Von Arx , William J. Linder , Mark D. Amundson
IPC分类号： A61N1365
CPC分类号： G01K13/002 , A61B5/0008 , A61B5/0031 , A61B5/7285 , A61N1/3655
摘要： An implantable medical device such as a cardiac pacemaker or implantable cardioverter/defibrillator with the capability of storing body temperature measurements taken periodically and/or when triggered by particular events.

107. 发明授权

US06614406B2 Circumferential antenna for an implantable medical device 有权
公开(公告)号：US06614406B2
公开(公告)日：2003-09-02
申请号：US10252494
申请日：2002-09-23
申请人： Mark D. Amundson , Jeffrey A. Von Arx , William J. Linder , Prashant Rawat , William R. Mass
发明人： Mark D. Amundson , Jeffrey A. Von Arx , William J. Linder , Prashant Rawat , William R. Mass
IPC分类号： H01Q140
CPC分类号： H01Q1/22 , A61N1/37229 , Y10S128/903
摘要： An apparatus and method for enabling far-field radio-frequency communications with an implantable medical device in which an antenna is embedded within a dielectric around the periphery of the device. Such a circumferential antenna saves space while still permitting far-field telemetry over a desired range of frequencies.

108. 发明授权

US06381491B1 Digitally trimmable resistor for bandgap voltage reference 有权
标题翻译：数字可调电阻，用于带隙电压参考
公开(公告)号：US06381491B1
公开(公告)日：2002-04-30
申请号：US09642287
申请日：2000-08-18
申请人： Keith R. Maile , Terrence L. Marshall , William J. Linder
发明人： Keith R. Maile , Terrence L. Marshall , William J. Linder
IPC分类号： A61N100
CPC分类号： A61N1/08 , G05F3/30
摘要： A bandgap voltage reference circuit implemented on an integrated circuit chip in which a proportional-to-temperature current is controlled by a current controlling resistor and converted to a voltage by a voltage controlling resistor, with either or both of the resistors being an integrated on-chip digitally trimmable resistor. The reference circuit is particularly suitable for application to circuitry used in implantable medical devices where off-chip resistors provide a channel by which noise can interfere with the operation of the circuit. The on-chip digitally trimmable resistor is implemented in accordance with the invention by a programmable switch matrix connected to a resistor network.
摘要翻译：一种在集成电路芯片上实现的带隙电压参考电路，其中比例温度电流由电流控制电阻器控制并通过电压控制电阻器转换成电压，其中一个或两个电阻器是集成在线的，芯片数字可调电阻。参考电路特别适用于可植入医疗设备中使用的电路，其中片外电阻器提供噪声可能干扰电路的操作的通道。片上可数字可调电阻器根据本发明通过连接到电阻器网络的可编程开关矩阵来实现。

109. 发明授权

US09357944B2 Impedance measurement and demodulation using implantable device 有权
标题翻译：使用可植入装置的阻抗测量和解调
公开(公告)号：US09357944B2
公开(公告)日：2016-06-07
申请号：US12350728
申请日：2009-01-08
申请人： Michael J. Lyden , William J. Linder , Angela M. Muttonen , George D. Ritzinger
发明人： Michael J. Lyden , William J. Linder , Angela M. Muttonen , George D. Ritzinger
IPC分类号： A61B5/05 , A61B5/053 , A61B5/029 , A61N1/365 , A61N1/37 , A61B5/04 , A61N1/372 , A61N1/39 , A61B5/046 , A61N1/362 , A61B5/0452 , A61B5/00 , A61N1/08
CPC分类号： A61B5/053 , A61B5/0031 , A61B5/029 , A61B5/04017 , A61B5/0452 , A61B5/046 , A61B5/0535 , A61B5/0538 , A61B5/6846 , A61B5/7203 , A61N1/3622 , A61N1/36521 , A61N1/3704 , A61N1/37241 , A61N1/3956 , A61N2001/083
摘要： An implantable medical device performs impedance measurement and demodulation, such as for obtaining lead impedance measurements, or thoracic impedance measurements, such as for extracting respiration, cardiac stroke, or fluid status information. A 4-point FIR filter demodulator can be used to demodulate a two-phase current excitation waveform. The demodulator can also be used to measure noise for triggering a noise response. Among other things, an increased excitation current level can be used when noise is deemed to be present.
摘要翻译：可植入医疗装置执行阻抗测量和解调，例如用于获得引线阻抗测量或胸部阻抗测量，例如用于提取呼吸，心脏搏动或流体状态信息。 4点FIR滤波解调器可用于解调两相电流激励波形。解调器也可用于测量用于触发噪声响应的噪声。除此之外，当认为存在噪声时，可以使用增加的励磁电流电平。

110. 发明授权

US08798742B2 Method and apparatus for adjusting cardiac event detection threshold based on dynamic noise estimation 有权
标题翻译：基于动态噪声估计调整心脏事件检测阈值的方法和装置
公开(公告)号：US08798742B2
公开(公告)日：2014-08-05
申请号：US12415619
申请日：2009-03-31
申请人： William J. Linder , Jeremy Maniak , Ron A. Balczewski
发明人： William J. Linder , Jeremy Maniak , Ron A. Balczewski
IPC分类号： A61N1/39 , A61B5/0428
CPC分类号： A61B5/04017 , A61N1/3704 , A61N1/3925 , A61N1/3962 , Y10S128/901
摘要： An implantable cardiac rhythm management (CRM) device includes a sensing and detection circuit that senses at least one cardiac signal and detects cardiac electrical events from the sensed cardiac signal using a detection threshold that is adjusted based on a dynamic noise estimation. The sensed cardiac signal is filtered to produce a filtered cardiac signal having a signal frequency band and a noise signal having a noise frequency band. The noise frequency band is substantially different from the signal frequency band. A dynamic noise floor is produced based on the noise signal and used as the minimum value for the detection threshold. A cardiac electrical is detected when the amplitude of the filtered cardiac signal exceeds the detection threshold.
摘要翻译：可植入心律管理（CRM）装置包括感测和检测电路，其感测至少一个心脏信号并且使用基于动态噪声估计调整的检测阈值从所感测的心脏信号检测心脏电气事件。所感测的心脏信号被滤波以产生具有信号频带的滤波心脏信号和具有噪声频带的噪声信号。噪声频带与信号频带基本不同。基于噪声信号产生动态底噪，并将其用作检测阈值的最小值。当过滤的心脏信号的幅度超过检测阈值时，检测心电。

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