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101. 发明申请

US20060061081A1 Compressed gas tank carrier assembly 审中-公开
标题翻译：压缩气罐车架总成
公开(公告)号：US20060061081A1
公开(公告)日：2006-03-23
申请号：US11223772
申请日：2005-09-09
申请人： Alfred Kresse , Konstantinos Triantos , David Young , Mark Brady-Rajdl
发明人： Alfred Kresse , Konstantinos Triantos , David Young , Mark Brady-Rajdl
IPC分类号： B60P3/22
CPC分类号： B60K15/07 , B60K1/04 , B60K15/063 , F17C13/083 , F17C2201/0109 , F17C2201/035 , F17C2201/056 , F17C2205/0126 , F17C2205/013 , F17C2205/0192 , F17C2205/0196 , F17C2221/012 , F17C2223/0123 , F17C2223/036 , F17C2270/0168 , F17C2270/0184 , H01M8/04208 , H01M2250/20 , Y02E60/321 , Y02T90/32
摘要： A carrier assembly for a compressed gas storage tank includes a first yoke defining a first concavity, and a second yoke defining a second concavity. The first and second concavities are sufficiently aligned such that a tank is at least partially containable within both the first and second concavities. In an exemplary embodiment, the first yoke also defines a third concavity and the second yoke defines a fourth concavity; the third and fourth concavities are sufficiently aligned such that another tank is at least partially containable therein. Preferably, at least one flexible strap retains the tanks with respect to the yokes.
摘要翻译：用于压缩气体储罐的载体组件包括限定第一凹部的第一轭和限定第二凹部的第二轭。第一和第二凹部足够对准，使得罐在第一和第二凹部内至少部分地可容纳。在示例性实施例中，第一轭还限定第三凹部，并且第二轭限定第四凹部; 第三和第四凹部足够对准，使得另一个罐至少部分地容纳在其中。优选地，至少一个柔性带将罐相对于轭架保持。

102. 发明申请

US20060021739A1 Method and system for evaluating fluid flow through a heat exchanger 有权
标题翻译：用于评估通过热交换器的流体流动的方法和系统
公开(公告)号：US20060021739A1
公开(公告)日：2006-02-02
申请号：US10909781
申请日：2004-08-02
申请人： David Young , John Coates , James Snow
发明人： David Young , John Coates , James Snow
IPC分类号： F28D15/00
CPC分类号： G01K17/06 , F28D1/035 , F28F2200/00 , F28F2265/16 , G01K17/12 , G01K2201/00
摘要： A heat exchanger evaluation system (84) includes a refrigeration subsystem (126) and a platform (94) in communication with the subsystem (126) for attachment of a heat exchanger (32). The system, (84) further includes a thermal imaging camera (168) and a monitor (100). A method (180) entails routing a fluid (38) through the heat exchanger (32) via the refrigeration subsystem (126). The camera (168) detects the temperature variation across the heat exchanger (32) as the fluid (38) flows through the heat exchanger, and provides successive thermal images representing the temperature variation responsive to the flow of the fluid (38). The thermal images are utilized to determine an efficacy of the flow through the heat exchanger (32). In particular, a determination can be made as to whether the flow deviates from a pre-determined flow path (79) of the fluid (38) through the heat exchanger.
摘要翻译：热交换器评估系统（84）包括与用于附接热交换器（32）的子系统（126）连通的制冷子系统（126）和平台（94）。该系统（84）还包括热成像相机（168）和监视器（100）。方法（180）需要经由制冷子系统（126）将流体（38）路由穿过热交换器（32）。当流体（38）流过热交换器时，照相机（168）检测穿过热交换器（32）的温度变化，并响应于流体（38）的流动提供代表温度变化的连续热图像。热图像用于确定通过热交换器（32）的流动的功效。特别地，可以确定流体是否偏离流体（38）的预定流动路径（79）通过热交换器。

103. 发明申请

US20060009603A1 Fibrillation-resistant polypropylene tape 审中-公开
标题翻译：抗纤维聚丙烯胶带
公开(公告)号：US20060009603A1
公开(公告)日：2006-01-12
申请号：US10888152
申请日：2004-07-09
申请人： David Young , Mohan Gownder , Rob Rowland
发明人： David Young , Mohan Gownder , Rob Rowland
IPC分类号： C08F110/00
CPC分类号： B29C55/06 , B29K2023/12 , D01D5/426 , D01F6/06
摘要： The present invention relates to fibrillation resistant polypropylene tape formed from the polymerization of propylene utilizing isospecific metallocene catalysts. The resulting polymerized isotactic polypropylene is heated, extruded and withdrawn as a film or sheet. The sheet is then slit longitudinally into tape segments and drawn in the longitudinal direction to a draw ratio of at least about 4.5:1 to produce an oriented tape. It has been found that these polypropylene tapes have improved resistance to fibrillation than those polypropylene tapes produced using Ziegler-Natta catalyst drawn at the same draw ratios.
摘要翻译：本发明涉及由使用异相茂金属催化剂的丙烯聚合形成的抗起纤抗菌聚丙烯带。将所得聚合的全同立构聚丙烯作为膜或片材加热，挤出和取出。然后将片材纵向狭缝切割成带段并沿纵向方向拉伸至至少约4.5:1的拉伸比，以产生取向的带。已经发现，与使用以相同拉伸比拉伸的齐格勒 - 纳塔催化剂制备的那些聚丙烯带相比，这些聚丙烯带具有改善的抗纤维化性能。

104. 发明申请

US20050255041A1 Cancerous disease modifying antibodies 审中-公开
公开(公告)号：US20050255041A1
公开(公告)日：2005-11-17
申请号：US10846266
申请日：2004-05-13
申请人： David Young , Susan Hahn , Helen Findlay
发明人： David Young , Susan Hahn , Helen Findlay
IPC分类号： A61K39/395 , A61K47/48 , A61K51/00 , A61K51/10 , A61P35/00 , C07K16/00 , C07K16/30 , C12N5/12 , G01N33/574
CPC分类号： A61K51/1051 , A61K47/6855 , C07K16/00
摘要： The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.

105. 发明申请

US20050244899A1 Laminin Receptor 1 Precursor Protein (37LRP) epitope delineated by an Hepatocellular carcinoma specific antibody 有权
标题翻译：层粘连蛋白受体1前体蛋白（37LRP）表位由肝细胞癌特异性抗体描绘
公开(公告)号：US20050244899A1
公开(公告)日：2005-11-03
申请号：US11079969
申请日：2005-03-14
申请人： David Young , Susan Hahn , Fortunata McConkey , Michelle Kelleher , Andrea Warner
发明人： David Young , Susan Hahn , Fortunata McConkey , Michelle Kelleher , Andrea Warner
IPC分类号： A61K39/395 , A61K47/48 , A61K51/10 , A61P35/00 , C07K16/30 , C12N5/12 , G01N33/53 , G01N33/566 , G01N33/567 , G01N33/574 , G01N33/68
CPC分类号： C07K16/303 , A61K47/6851 , C07K16/30 , C07K16/3069 , G01N33/57415 , G01N33/57419 , G01N33/57438 , G01N33/57449 , G01N33/57476 , G01N33/6893
摘要： This invention relates to the diagnosis and treatment of cancerous diseases, particularly to such diagnosis and treatment which revolves around the ability of the 5LAC-23 monoclonal antibody (or antigenic binding fragments derived therefrom) to bind with the Laminin Receptor 1 Precursor Protein 37LRP; and most particularly to diagnosis and treatment of Hepatocellular Carcinoma by various means which rely upon direct binding of 5LAC-23 with the particular antigenic moiety specifically recognized thereby and generally overexpressed in Hepatocellular carcinoma cells. The invention additionally relates to the treatment of such cells with conjugated moieties effective to aid in differentiation, treatment and diagnostic imaging thereof.
摘要翻译：本发明涉及癌细胞疾病的诊断和治疗，特别涉及以5LAC-23单克隆抗体（或其衍生自其衍生的抗原结合片段）与层粘连蛋白受体1前体蛋白37LRP结合的能力的诊断和治疗; 最特别的是通过各种手段诊断和治疗肝细胞癌，这些方法依赖于5LAC-23与由此特异性识别的特定抗原部分的直接结合，并且通常在肝细胞癌细胞中过表达。本发明还涉及这种具有有助于分化，治疗和诊断成像的共轭部分的细胞的治疗。

106. 发明申请

US20050154053A1 Methods and compositions for immunomodulation 失效
标题翻译：用于免疫调节的方法和组合物
公开(公告)号：US20050154053A1
公开(公告)日：2005-07-14
申请号：US10966874
申请日：2004-10-15
申请人： Ildiko Rhijn , David Young , D. Moody
发明人： Ildiko Rhijn , David Young , D. Moody
IPC分类号： A61K20060101 , A61K31/343 , C07D307/87
CPC分类号： A61K31/343
摘要： Novel antigens are provided herein. The antigens are associated with recognition of CD1 molecules by T cells. These antigens can be used as antigens, adjuvants or as immunomodulatory agents in a variety of therapeutic and prophylactic applications.
摘要翻译：本文提供新型抗原。抗原与T细胞对CD1分子的识别有关。这些抗原可以用作各种治疗和预防应用中的抗原，佐剂或免疫调节剂。

107. 发明申请

US20050152340A1 Network session management 有权
标题翻译：网络会话管理
公开(公告)号：US20050152340A1
公开(公告)日：2005-07-14
申请号：US10979317
申请日：2004-11-02
申请人： Eric Voit , Edward Balkovich , William Goodman , Jayant Gadre , Patrick White , David Young
发明人： Eric Voit , Edward Balkovich , William Goodman , Jayant Gadre , Patrick White , David Young
IPC分类号： H04L12/14 , H04L12/28 , H04L12/56 , H04L12/66 , H04L29/06 , H04M7/00
CPC分类号： H04L65/1069 , H04L12/14 , H04L12/1403 , H04L12/141 , H04L12/1414 , H04L12/1421 , H04L12/1439 , H04L12/1446 , H04L12/1453 , H04L12/1457 , H04L12/1464 , H04L12/1482 , H04L12/1485 , H04L29/06 , H04L29/06027 , H04L29/12245 , H04L61/203 , H04L63/08 , H04L63/10 , H04L65/103 , H04L65/104 , H04L65/1043 , H04L2463/102 , H04M7/1285 , H04M15/41 , H04M15/56 , H04M2215/014 , H04M2215/0164 , H04M2215/0176 , H04M2215/018 , H04M2215/2046 , H04M2215/22 , H04W4/16 , Y10S379/90
摘要： A communication system providing telephony communication across combined circuit switched and packet switched networks, such as a telephone network and the Internet, which are connectable to terminals, such as telephones and computers, for selective communication therebetween. The communication system includes an authorization and account control object in the packet switched network, multiple gateways between the circuit switched and packet switched networks providing controlled connectivity between those networks, and an information retrieval object in the packet switched network, wherein the authorization and account control object maintains a substantially real time record of user accounts and usage, and the information and retrieval object provides substantially real time retrieval of selected information from the authorization and account control object. The retrieval object provides on demand to terminals which provide authentication for access to an identified account information regarding that account. The information regarding the account is substantially real time information including information with respect to communications in progress, which are chargeable to the account which has been authenticated. The authorization and account control object is preferably a unitary logical object having distributed instances thereof handling multitudinous accounts of widely separated terminals. The retrieval object provides isolation of the authorization and account control object permitting simultaneous multitasking by the authorization and account control object and the retrieval object respectively.
摘要翻译：一种通过组合电路交换和分组交换网络（例如电话网络和因特网）提供电话通信的通信系统，其可连接到诸如电话和计算机之类的终端，用于其间的选择性通信。通信系统包括分组交换网络中的授权和帐户控制对象，电路交换和分组交换网络之间的多个网关，提供这些网络之间的受控连接，以及分组交换网络中的信息检索对象，其中授权和帐户控制对象维护用户帐户和使用的基本实时记录，并且信息和检索对象从授权和帐户控制对象提供基本上实时检索所选择的信息。检索对象根据需要提供终端，该终端提供用于访问关于该帐户的所识别的帐户信息的认证。关于账户的信息基本上是实时信息，包括关于正在进行的通信的信息，这些信息可以对已被认证的帐户收费。授权和帐户控制对象优选地是具有分布式实例的单一逻辑对象处理广泛分离的终端的众多帐户。检索对象提供授权和帐户控制对象的隔离，允许分别由授权和帐户控制对象和检索对象同时进行多任务。

108. 发明申请

US20050095663A1 Process for screening fungitoxic compounds 审中-公开
标题翻译：筛选真菌化合物的方法
公开(公告)号：US20050095663A1
公开(公告)日：2005-05-05
申请号：US10486524
申请日：2003-06-17
申请人： David Young , Richard Slawecki , Ronald Ross Jr
发明人： David Young , Richard Slawecki , Ronald Ross Jr
IPC分类号： A01N25/02 , A01N25/08 , A01N37/02 , A01N43/58 , A61K31/50 , A61K45/00 , A61P31/10 , A61P43/00 , C12Q1/02 , C12Q1/18 , C12Q1/26 , A01N37/00
CPC分类号： C12Q1/18 , C12Q1/26 , G01N2333/37 , G01N2333/90245 , G01N2500/02
摘要： Methods for identifying fungitoxic compounds are disclosed based on inhibition of the enzyme Δ-9 fatty acid de-saturase.
摘要翻译：基于对Δ-9脂肪酸脱饱和酶的抑制来公开鉴定真菌化合物的方法。

109. 发明申请

US20050074737A1 Cultural ambassador exchange method and system 审中-公开
标题翻译：文化大使交流方式和制度
公开(公告)号：US20050074737A1
公开(公告)日：2005-04-07
申请号：US10679735
申请日：2003-10-06
申请人： Alan Young , David Young , Mary Breen , Debra Martin , Gregory Hopper
发明人： Alan Young , David Young , Mary Breen , Debra Martin , Gregory Hopper
IPC分类号： G09B19/00 , G09B25/00
CPC分类号： G09B19/00 , G06Q30/0226
摘要： A system and method for management of participants within an education-based cultural exchange program, wherein the system and method provide for a multiplicity of participants to share cultural-related information and other information not specifically related to the cultural distinctions of a respective participant within a phased program, the phases including at least acclimation, teaching, and sharing phases, and the program further providing for self-administration of administrative matters, tracking participants and information within the program framework and timeframe, and auditing the program.
摘要翻译：一种用于管理基于教育的文化交流计划中的参与者的系统和方法，其中该系统和方法为多个参与者提供了分享文化相关信息和其他信息，而这些信息与其内的相关参与者的文化差异无关阶段包括至少适应，教学和共享阶段，方案进一步规定行政事项的自我管理，在方案框架和时间框架内跟踪与会者和信息，并对方案进行审计。

110. 发明申请

US20050063967A1 Cytotoxicity mediation of cells evidencing surface expression of MCSP 失效
标题翻译：证实MCSP表面表达的细胞的细胞毒性调解
公开(公告)号：US20050063967A1
公开(公告)日：2005-03-24
申请号：US10949846
申请日：2004-09-24
申请人： David Young , Susan Hahn , Helen Findlay , Alison Ferry
发明人： David Young , Susan Hahn , Helen Findlay , Alison Ferry
IPC分类号： A61K51/10 , C07K16/00 , C07K16/30 , G01N33/574 , A61K39/395
CPC分类号： G01N33/57492 , A61K47/6851 , A61K51/1045 , A61K51/1051 , A61K51/1096 , A61K2039/505 , C07K14/4748 , C07K16/00 , C07K16/30 , C07K16/3015 , C07K16/3023 , C07K16/3046 , C07K16/3053 , C07K16/3069 , C07K2317/34 , C12N9/1051 , G01N33/56966 , G01N33/5743 , G01N33/57484
摘要： This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response. The invention further relates to binding assays which utilize the CDMABs of the instant invention.
摘要翻译：本发明涉及癌症的诊断和治疗，特别涉及肿瘤细胞的细胞毒性的介导; 并且最特别地涉及使用任选与一种或多种化学治疗剂组合的癌性疾病修饰抗体（CDMAB）作为起始细胞毒性应答的手段。本发明还涉及利用本发明的CDMABs的结合测定法。

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