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101. 发明授权

US06635653B2 Spiropyrazole compounds 有权
标题翻译：螺吡唑化合物
公开(公告)号：US06635653B2
公开(公告)日：2003-10-21
申请号：US10126506
申请日：2002-04-18
申请人： R. Richard Goehring , Gary Lee , Parviz Gharagozloo , Sam Victory , Donald Kyle
发明人： R. Richard Goehring , Gary Lee , Parviz Gharagozloo , Sam Victory , Donald Kyle
IPC分类号： A61K31438
CPC分类号： C07D471/10
摘要： A compound of the formula (I): wherein Z, W, A, B, C, R1, R2, Q and n are as disclosed herein.
摘要翻译：式（I）的化合物：其中Z，W，A，B，C，R 1，R 2，Q和n如本文所公开。

102. 发明授权

US06470996B1 Wireline acoustic probe and associated methods 有权
标题翻译：有线声学探头及相关方法
公开(公告)号：US06470996B1
公开(公告)日：2002-10-29
申请号：US09540000
申请日：2000-03-30
申请人： Donald Kyle , Vimal Shah
发明人： Donald Kyle , Vimal Shah
IPC分类号： G01V140
CPC分类号： G01V1/46
摘要： A wireline acoustic probe and associated methods provide enhanced calibration and communication capabilities in a downhole acoustic communication system. In a described embodiment, an acoustic probe is conveyed on a wireline to a position proximate a downhole acoustic transmitter. A command is transmitted acoustically from the probe to the transmitter, causing the transmitter to generate acoustic frequency sweeps. The sweeps are received by the probe proximate a downhole acoustic receiver, permitting an optimum acoustic transmission frequency to be selected.
摘要翻译：有线声学探测器和相关方法在井下声学通信系统中提供增强的校准和通信能力。在所描述的实施例中，声探针在有线线路上传送到靠近井下声发射器的位置。命令从探头声发射到发射器，使发射器产生声频扫描。扫描由靠近井下声学接收器的探头接收，允许选择最佳的声学传播频率。

103. 发明授权

US08748695B2 Molecular markers linked to PPO inhibitor tolerance in soybeans 有权
标题翻译：与大豆中PPO抑制剂耐受性相关的分子标记
公开(公告)号：US08748695B2
公开(公告)日：2014-06-10
申请号：US12694255
申请日：2010-01-26
申请人： Julian Chaky , Kevin A. Fengler , Jennifer A. Klaiber , Donald Kyle , Bailin Li , Mark D. Vogt
发明人： Julian Chaky , Kevin A. Fengler , Jennifer A. Klaiber , Donald Kyle , Bailin Li , Mark D. Vogt
IPC分类号： A01H1/02 , A01H1/04 , A01H5/10
CPC分类号： C12Q1/6895 , A01H1/02 , A01H1/04 , A01H5/10 , A01N47/38 , C12N15/8274 , C12Q2600/13 , C12Q2600/156 , C12Q2600/172
摘要： This invention relates generally to the detection of genetic differences among soybeans. More particularly, the invention relates to soybean quantitative trait loci (QTL) for tolerance to protoporphyrinogen oxidase inhibitors, to soybean plants possessing these QTLs, which map to a novel chromosomal region, and to genetic markers that are indicative of phenotypes associated with protoporphyrinogen oxidase inhibitor tolerance. Methods and compositions for use of these markers in genotyping of soybean and selection are also disclosed.
摘要翻译：本发明一般涉及大豆遗传差异的检测。更具体地，本发明涉及对原卟啉原氧化酶抑制剂的耐受性的大豆数量性状基因座（QTL），具有这些QTL的大豆植物，其映射到新的染色体区域，以及指示与原卟啉原氧化酶抑制剂相关的表型的遗传标记公差。还公开了在大豆基因分型中选择使用这些标记的方法和组合物。

104. 发明授权

US08697941B2 Molecular markers linked to PPO inhibitor tolerance in soybeans 有权
公开(公告)号：US08697941B2
公开(公告)日：2014-04-15
申请号：US12506498
申请日：2009-07-21
申请人： Donald Kyle , Mark D. Vogt
发明人： Donald Kyle , Mark D. Vogt
IPC分类号： A01H1/04
CPC分类号： A01N43/653 , A01H1/04 , A01H5/10 , C12Q1/6895 , C12Q2600/13 , C12Q2600/156 , C12Q2600/172
摘要： This invention relates generally to the detection of genetic differences among soybeans. More particularly, the invention relates to soybean quantitative trait loci (QTL) for tolerance to protoporphyrinogen oxidase inhibitors, to soybean plants possessing these QTLs, which map to a novel chromosomal region, and to genetic markers that are indicative of phenotypes associated with protoporphyrinogen oxidase inhibitor tolerance. Methods and compositions for use of these markers in genotyping of soybean and selection are also disclosed.

105. 发明授权

US08686241B2 Soybean variety XB21F12 失效
标题翻译：大豆品种XB21F12
公开(公告)号：US08686241B2
公开(公告)日：2014-04-01
申请号：US13409264
申请日：2012-03-01
申请人： Donald Kyle , Martin A. Fabrizius , Michael T. Roach
发明人： Donald Kyle , Martin A. Fabrizius , Michael T. Roach
IPC分类号： C12N15/82 , A01H1/00 , A01H4/00 , A01H5/00 , A01H5/10
CPC分类号： A01H5/10
摘要： A novel soybean variety, designated XB21F12 is provided. Also provided are the seeds of soybean variety XB21F12, cells from soybean variety XB21F12, plants of soybean XB21F12, and plant parts of soybean variety XB21F12. Methods provided include producing a soybean plant by crossing soybean variety XB21F12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB21F12, methods for producing other soybean varieties or plant parts derived from soybean variety XB21F12, and methods of characterizing soybean variety XB21F12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB21F12 are further provided.
摘要翻译：提供了一种名为XB21F12的新品种。还提供了大豆品种XB21F12的种子，大豆品种XB21F12的细胞，大豆XB21F12的植物和大豆品种XB21F12的植物部分。提供的方法包括通过将大豆品种XB21F12与另一种大豆植物杂交来生产大豆植物，将转基因性状，突变特征和/或天然性状插入大豆品种XB21F12的方法，生产其他大豆品种的方法或衍生自大豆品种XB21F12，以及大豆品种XB21F12的表征方法。还提供了通过这些方法生产和/或从大豆品种XB21F12得到的大豆种子，细胞，植物，种质，育种系，品种和植物部分。

106. 发明授权

US08636062B2 System and method for downhole communication 失效
标题翻译：井下通信系统和方法
公开(公告)号：US08636062B2
公开(公告)日：2014-01-28
申请号：US12969379
申请日：2010-12-15
申请人： Michael L. Fripp , Donald Kyle , Pete Dagenais
发明人： Michael L. Fripp , Donald Kyle , Pete Dagenais
IPC分类号： E21B47/00 , E21B47/12
CPC分类号： E21B47/12 , E21B47/091
摘要： A method of servicing a wellbore extending from a surface and penetrating a subterranean formation is provided. The method comprises placing a assembly in the wellbore, wherein the assembly comprises at least a first downhole tool, a signal receiver subassembly, and a conveyance between the first downhole tool and the surface. The method further comprises the signal receiver subassembly receiving a first signal generated by contact between the wellbore and the assembly and initiating a first function of the first downhole tool based on the first signal.
摘要翻译：提供了一种维护从表面延伸并穿透地层的井眼的方法。该方法包括将组件放置在井眼中，其中组件至少包括第一井下工具，信号接收器子组件以及第一井下工具与表面之间的输送。该方法还包括信号接收器子组件，其接收由井筒和组件之间的接触产生的第一信号，并且基于第一信号启动第一井下工具的第一功能。

107. 发明申请

US20120324598A1 GENETIC LOCI ASSOCIATED WITH FUSARIUM SOLANI TOLERANCE IN SOYBEAN 有权
标题翻译：遗传位置与大豆中的大豆耐盐性相关
公开(公告)号：US20120324598A1
公开(公告)日：2012-12-20
申请号：US13594309
申请日：2012-08-24
申请人： Hong Lu , Feng Han , Scott Sebastian , Donald Kyle , Paul Stephens , Thomas C. Corbin , Jeffrey Thompson
发明人： Hong Lu , Feng Han , Scott Sebastian , Donald Kyle , Paul Stephens , Thomas C. Corbin , Jeffrey Thompson
IPC分类号： C12Q1/68 , A01H1/02
CPC分类号： C12Q1/6895 , A01H1/04 , A01H5/10 , C12N15/8282 , C12Q2600/13 , C12Q2600/156
摘要： The invention relates to methods and compositions for identifying soybean plants that are tolerant, have improved tolerance or are susceptible to Fusarium solani infection (the causative agent of sudden death syndrome or SDS). The methods use molecular genetic markers to identify, select and/or construct disease-tolerant plants or identify and counterselect disease-susceptible plants. Soybean plants that display tolerance or improved tolerance to Fusarium solani infection that are generated by the methods of the invention are also a feature of the invention.
摘要翻译：本发明涉及用于鉴定耐受性好，具有改善的耐受性或易受镰孢镰刀菌感染（猝死综合征或SDS的致病因子）的大豆植物的方法和组合物。该方法使用分子遗传标记来鉴定，选择和/或构建耐病植物或识别并对抗疾病敏感植物。通过本发明的方法产生的显示对茄病菌感染的耐受性或改善的耐受性的大豆植物也是本发明的一个特征。

108. 发明申请

US20120095049A1 NOCICEPTIN ANALOGS 有权
公开(公告)号：US20120095049A1
公开(公告)日：2012-04-19
申请号：US13051629
申请日：2011-03-18
申请人： Qun SUN , R. Richard Goehring , Donald Kyle , Zhengming Chen , Sam Victory , John Whitehead
发明人： Qun SUN , R. Richard Goehring , Donald Kyle , Zhengming Chen , Sam Victory , John Whitehead
IPC分类号： A61K31/454 , A61P25/04 , C07D401/04
CPC分类号： C07D401/04 , C07D235/26 , C07D263/58 , C07D405/14 , C07D413/04 , C07D413/14 , C07D471/04
摘要： A compound of the formula (I), (II), (III) or (IV) wherein Z, A, B, C, R, R1, R2, Q, and n are as described herein.
摘要翻译：其中Z，A，B，C，R，R 1，R 2，Q和n如本文所述的式（I），（II），（III）或（IV）

109. 发明授权

US07678809B2 Benzimidazole compounds having nociceptin receptor affinity 失效
标题翻译：具有伤害感受器受体亲和力的苯并咪唑化合物
公开(公告)号：US07678809B2
公开(公告)日：2010-03-16
申请号：US11494826
申请日：2006-07-28
申请人： Donald Kyle , Richard R. Goehring , Bin Shao
发明人： Donald Kyle , Richard R. Goehring , Bin Shao
IPC分类号： A61K31/44
CPC分类号： C07D401/04
摘要： Disclosed are compounds of the formula (I) wherein A, R1, R2, R3, R4 and X1 are as disclosed herein. The compounds have affinity for the ORL1 receptor and are useful in the treatment of chronic and acute pain.
摘要翻译：公开了式（I）的化合物，其中A，R 1，R 2，R 3，R 4和X 1如本文所公开。该化合物对ORL1受体具有亲和力，可用于治疗慢性和急性疼痛。

110. 发明申请

US20090227615A1 Oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone 审中-公开
标题翻译：具有小于25ppm的14-羟可待因酮的羟考酮盐酸盐
公开(公告)号：US20090227615A1
公开(公告)日：2009-09-10
申请号：US12380800
申请日：2009-03-04
申请人： Robert Chapman , Lonn S. Rider , Qi Hong , Donald Kyle , Robert Kupper
发明人： Robert Chapman , Lonn S. Rider , Qi Hong , Donald Kyle , Robert Kupper
IPC分类号： A61K31/485 , A61P25/04
CPC分类号： C07D489/08 , A61K9/14 , A61K9/20 , A61K9/2095 , A61K9/48 , A61K9/4833 , A61K31/485 , C07D489/02 , C07D489/04
摘要： In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.
摘要翻译：在某些实施方案中，本发明涉及制备具有小于25ppm的14-羟可待因酮的盐酸羟考酮组合物的方法。

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