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101. 发明申请

US20070059214A1 Closing blade for deformable valve in a microfluidic device and method 有权
标题翻译：微流体装置和方法中的可变形阀的关闭叶片
公开(公告)号：US20070059214A1
公开(公告)日：2007-03-15
申请号：US11598480
申请日：2006-11-13
申请人： David Cox , Zbigniew Bryning
发明人： David Cox , Zbigniew Bryning
IPC分类号： B01L3/00
CPC分类号： F16K99/0026 , B01L3/502715 , B01L3/502738 , B01L2200/0689 , B01L2300/0816 , B01L2400/0655 , F16K99/0001 , F16K99/003 , F16K99/0034 , F16K2099/008 , Y10T436/2575
摘要： A microfluidic manipulation system is provided that includes a blade for manipulating deformable material and at least one movable support that is capable of moving the blade into contact with a microfluidic device including a deformable feature. When the microfluidic device is operatively held by a holder, a movable support can position the distal end of the blade relative to the microfluidic device and move the contact tip surface of the blade such that it deforms the deformable feature.
摘要翻译：提供了一种微流体操纵系统，其包括用于操纵可变形材料的刀片和能够使刀片与包括可变形特征的微流体装置接触的至少一个可移动支撑件。当微流体装置由保持器可操作地保持时，可移动支撑件可以相对于微流体装置定位叶片的远端并移动叶片的接触尖端表面，使得其使可变形特征变形。

102. 发明申请

US20070037198A1 Methods for genetic analysis 审中-公开
标题翻译：遗传分析方法
公开(公告)号：US20070037198A1
公开(公告)日：2007-02-15
申请号：US11510261
申请日：2006-08-25
申请人： David Cox , Mark McCamish
发明人： David Cox , Mark McCamish
IPC分类号： C12Q1/68 , G06F19/00
CPC分类号： G06Q50/24 , G16B20/00 , G16B40/00
摘要： Methods are described for assessing an individual's likelihood of developing or exhibiting a multifactorial trait, and for predicting the effectiveness of a drug treatment regimen in an individual. The methods include determining a plurality of genotypes for the individual at a plurality of biallelic polymorphic loci, using the genotypes to compute a score for the individual, and comparing the score to at least one threshold value. Genetic tests are also described for assessing an individual's likelihood of developing or exhibiting a multifactorial trait.
摘要翻译：描述了评估个体发展或展现多因素性状的可能性以及用于预测个体药物治疗方案的有效性的方法。所述方法包括使用基因型来计算个体的分数，并将评分与至少一个阈值进行比较来确定个体在多个双重多态性基因座上的多种基因型。还描述了遗传测试来评估个体发展或表现多因素性状的可能性。

103. 发明申请

US20070025955A1 TISSUE ADHESIVE SEALANT 审中-公开
标题翻译：组织胶粘剂
公开(公告)号：US20070025955A1
公开(公告)日：2007-02-01
申请号：US11535111
申请日：2006-09-26
申请人： Johan Lowinger , Bruno Lowinger , Frank DeLustro , David Cox , David Browdie
发明人： Johan Lowinger , Bruno Lowinger , Frank DeLustro , David Cox , David Browdie
IPC分类号： A61K39/395 , A61K31/785
CPC分类号： A61L24/102 , A61L24/108
摘要： A tissue adhesive sealant includes a cross-linkable protein in a solution that when combined with a cross-linking agent solution including an aldehyde and amino acid containing species reactive with the aldehyde cross-links to form a seal. The sealant is well suited for bonding tissue alone or in combination with a patch. The ratio between the aldehyde and the amino acid containing species is between 20:1 and 1:1 on an aldehyde moiety:amino acid or peptide subunit molar basis. Particularly strong seals are formed when the protein and cross-linking agent are present in a molar ratio of between 15:1 and 1:1.
摘要翻译：组织粘合剂密封剂包括在与包含醛和氨基酸的交联剂溶液组合的溶液中的可交联蛋白质，所述交联剂溶液含有与醛交联反应的物质以形成密封。密封剂非常适合单独粘合组织或与贴片组合。醛和含氨基酸的物质之间的比例在醛部分上为20:1和1:1之间：氨基酸或肽亚基摩尔数。当蛋白质和交联剂以15:1至1:1的摩尔比存在时，形成特别强的密封。

104. 发明申请

US20060110486A1 Potting method 有权
标题翻译：灌封法
公开(公告)号：US20060110486A1
公开(公告)日：2006-05-25
申请号：US11197969
申请日：2005-08-05
申请人： David Cox , Georg Schnieder , Fufang Zha , Joachim Muller , Cinzia Lea
发明人： David Cox , Georg Schnieder , Fufang Zha , Joachim Muller , Cinzia Lea
IPC分类号： B29C31/00
CPC分类号： B01D63/022
摘要： A method of forming a pot for an array of hollow fibre membranes (7) is provided, including the steps of placing the ends (6) of the fibre membranes (7) in a mould (5); forming a first layer (20) of curable resin material in a non-cured state around the fibre membrane ends (6), applying a second layer (21) of a polyurethane resin material to the first layer (20) prior to full curing of the first layer, the polyurethane resin material layer being chemically reactive with the first layer material to form an adhesive bond therebetween; at least partially curing both layers and removing the pot formed from the mould (5), wherein the second layer material is of higher flexibility than the first layer material when each layer is fully cured. Apparatus for performing the method is also disclosed.
摘要翻译：提供一种形成中空纤维膜阵列（7）的罐的方法，包括将纤维膜（7）的端部（6）放置在模具（5）中的步骤; 在所述纤维膜端部（6）的周围形成处于非固化状态的可固化树脂材料的第一层（20），在完全固化所述第一层（20）之前，向所述第一层（20）施加聚氨酯树脂材料的第二层（21）所述第一层，所述聚氨酯树脂材料层与所述第一层材料发生化学反应，以在其间形成粘结剂; 至少部分地固化两层并移除由模具（5）形成的罐，其中当每层完全固化时，第二层材料比第一层材料具有更高的柔韧性。还公开了用于执行该方法的装置。

105. 发明申请

US20060106821A1 Ownership management of containers in an application server environment 审中-公开
标题翻译：应用服务器环境中容器的所有权管理
公开(公告)号：US20060106821A1
公开(公告)日：2006-05-18
申请号：US10988470
申请日：2004-11-12
申请人： David Cox , Craig Lawton , Jonathan Lewis , Christopher Peters , Lorin Ullmann
发明人： David Cox , Craig Lawton , Jonathan Lewis , Christopher Peters , Lorin Ullmann
IPC分类号： G06F7/00
CPC分类号： G06F21/604 , G06F21/105 , G06F21/121 , G06F2221/2101 , G06F2221/2117 , G06F2221/2141
摘要： A method, computer program product and system for determining ownership of containers. An installer program may edit stored information, such as ownership, about software component(s) it installed in a container. Upon a subsequent installer program planning to install a software component in that container, software, referred to as a “collector,” may identify the owners of the software components stored in that container. The collector may then search the rules in a rules database to determine the ownership of the container based on the ownership of the software components in the container. By mapping the software components stored in a container with their respective owners, the ownership of a container may be determined.
摘要翻译：一种用于确定集装箱所有权的方法，计算机程序产品和系统。安装程序可以编辑存储的信息，例如所有权，关于它安装在容器中的软件组件。在随后的安装程序计划在该容器中安装软件组件时，被称为“收集器”的软件可以标识存储在该容器中的软件组件的所有者。然后，收集器可以搜索规则数据库中的规则，以基于容器中的软件组件的所有权来确定容器的所有权。通过将存储在容器中的软件组件与其各自所有者进行映射，可以确定容器的所有权。

106. 发明申请

US20060106801A1 Securing location of an installed middleware application and securing location of containers contained within installed middleware application 审中-公开
标题翻译：确保安装的中间件应用程序的位置，并确保安装的中间件应用程序中包含的容器的位置
公开(公告)号：US20060106801A1
公开(公告)日：2006-05-18
申请号：US10988473
申请日：2004-11-12
申请人： David Cox , Craig Lawton , Jonathan Lewis , Christopher Peters , Lorin Ullmann , Douglas Wood
发明人： David Cox , Craig Lawton , Jonathan Lewis , Christopher Peters , Lorin Ullmann , Douglas Wood
IPC分类号： G06F17/30 , G06F7/00
CPC分类号： G06F21/10 , G06F21/6209 , H04L9/0894 , H04L2209/60
摘要： A method, computer program product and system for protecting the location of an installed middleware application. An installer program may generate a private/public key pair at build time of a middleware application. Upon the installer program installing the middleware application, the installation location of the middleware application may be encrypted using the generated private key and then discarding the private key. The encrypted installation location of the middleware application may be decrypted by a subsequent installer program upon receiving a public key from the developer of the middleware application. Since the public key was not shipped with the middleware application, an illegitimate program, such as a Trojan horse, may not be able to decrypt the installation location of the middleware application. Since the public key may only be obtained from the developer of the middleware application, only legitimate programs may be able to decrypt the location of the installed middleware application.
摘要翻译：一种用于保护安装的中间件应用程序的位置的方法，计算机程序产品和系统。安装程序可以在中间件应用程序的构建时生成私钥/公钥对。在安装程序安装中间件应用程序时，中间件应用程序的安装位置可以使用生成的私钥进行加密，然后丢弃私钥。中间件应用程序的加密安装位置可以在从中间件应用程序的开发人员接收到公钥时由后续安装程序解密。由于公钥未随中间件应用程序一起提供，因此非法程序（如特洛伊木马）可能无法解密中间件应用程序的安装位置。由于公钥只能从中间件应用程序的开发人员获得，所以只有合法的程序才能解密所安装的中间件应用程序的位置。

107. 发明授权

US07024174B2 Method and system for data management in electronic payments transactions 有权
公开(公告)号：US07024174B2
公开(公告)日：2006-04-04
申请号：US10200275
申请日：2002-07-22
申请人： Dan Nagy , Paul Goott , John Landry , David Cox , Michael C. Pang , Joe Favole , Michael Thompson
发明人： Dan Nagy , Paul Goott , John Landry , David Cox , Michael C. Pang , Joe Favole , Michael Thompson
IPC分类号： H04M11/00
CPC分类号： G07F7/1008 , G06Q20/04 , G06Q20/24 , G06Q20/26 , G06Q20/32 , G06Q20/322 , G06Q20/325 , G06Q20/341 , G06Q20/385 , G06Q20/4014 , G06Q30/04 , G07F17/0014 , H04M15/68 , H04M15/765 , H04M15/7652 , H04M17/00 , H04M17/103 , H04M17/106 , H04M17/20 , H04M17/204 , H04M2017/12 , H04M2017/14 , H04M2017/24 , H04M2215/0196 , H04M2215/2026 , H04M2215/32 , H04M2215/724 , H04M2215/7245 , H04W4/24
摘要： A method and system for prepaying wireless telecommunications charges utilizes computer hardware and software including, for example, a user's mobile phone, a mobile operator's interactive voice response unit, a mobile payments interactive voice response unit, SMS, test messaging, email, ATM, kiosk, the Internet, and/or WAP or the like, a mobile payments engine, a mobile operator's prepaid billing system, a subscriber database, a payment gateway, and a transaction processing platform. The mobile payments engine receives information identifying a user's wireless telecommunication device via the mobile payments interactive voice response unit, passes the information to the mobile operator's billing system with a request for validation of a mobile account for the user, and if validation is received, the mobile payments engine receives financial source account and user identity verification information from the user, assigns a mobile personal identification number for the user, and arranges a credit from the source account to the user's mobile account.

108. 发明申请

US20060046304A1 Thermal device, system, and method, for fluid processing device 有权
公开(公告)号：US20060046304A1
公开(公告)日：2006-03-02
申请号：US10926915
申请日：2004-08-26
申请人： John Shigeura , Janice Shigeura , Sean Desmond , David Cox
发明人： John Shigeura , Janice Shigeura , Sean Desmond , David Cox
IPC分类号： G01N33/00
CPC分类号： G05D23/24 , G05D23/192 , G05D23/20 , G05D23/22 , Y02P20/129 , Y10S435/809
摘要： A device, system, and method are provided for thermally treating a fluid processing device. According to various embodiments, a system is provided that can include a thermal device and a fluid processing device holder. The thermal device can include a first block having a thermal conductivity greater than 0.5 Watt per centimeter Kelvin (W/cm·K), a second block having a thermal conductivity greater than 0.5 W/cm·K, and a heat-pump device disposed between the first block and the second block. The heat-pump device can transfer thermal energy from at least one of the first block and the second block to the other of the first block and the second block. The fluid processing device holder can hold a fluid processing device in a heat-transfer position with respect to the first block and the second block. The fluid processing device can be a microfluidic device.

109. 发明申请

US20050196770A1 Methods for genetic analysis 有权
标题翻译：遗传分析方法
公开(公告)号：US20050196770A1
公开(公告)日：2005-09-08
申请号：US10956224
申请日：2004-09-30
申请人： David Cox , Mark McCamish
发明人： David Cox , Mark McCamish
IPC分类号： C12Q1/68 , G01N33/48 , G01N33/50 , G06F19/00
CPC分类号： G06F19/18 , G06F19/24 , G06Q50/24
摘要： Several methods are described for assessing an individual's likelihood of developing or exhibiting a multifactorial trait. The methods include determining a plurality of genotypes for the individual at a plurality of biallelic polymorphic loci, using the genotypes to compute a score for the individual, and comparing the score to at least one threshold value.
摘要翻译：描述了用于评估个体发展或表现多因素性状的可能性的几种方法。所述方法包括使用基因型来计算个体的分数，并将评分与至少一个阈值进行比较来确定个体在多个双重多态性基因座上的多种基因型。

110. 发明申请

US20050133438A1 Hollow fibre restraining system 有权
标题翻译：中空纤维束缚系统
公开(公告)号：US20050133438A1
公开(公告)日：2005-06-23
申请号：US11056532
申请日：2005-02-11
申请人： Fufang Zha , David Cox
发明人： Fufang Zha , David Cox
IPC分类号： B01D63/00 , B01D63/02 , B01D65/00
CPC分类号： B01D65/00 , B01D63/02 , B01D2313/06 , B65D2101/00
摘要： A restraining system for hollow fibres is provided. The restraining system includes a plurality of longitudinally extending elements spaced from one another and supported by a number of discrete spacer elements, each spacer element extending generally transverse of said longitudinal elements, such that in combination with said longitudinal elements they define a cage-like structure.
摘要翻译：提供了一种中空纤维的限制系统。约束系统包括彼此间隔开并由许多分立的间隔元件支撑的多个纵向延伸的元件，每个隔离元件大致横向于所述纵向元件延伸，使得与所述纵向元件组合，它们限定了笼状结构。

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