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101. 发明申请

US20130292592A1 DEVICE FOR CONNECTING OR FILLING AND METHOD 有权
公开(公告)号：US20130292592A1
公开(公告)日：2013-11-07
申请号：US13874839
申请日：2013-05-01
申请人： Daniel Py
发明人： Daniel Py
IPC分类号： F16L29/02
CPC分类号： F16L29/02 , A61M39/18 , A61M39/26 , A61M2039/268 , B65B3/003 , B65B39/001
摘要： A valve comprises a shell, a flexible valve member sealingly mounted within the shell, and a valve body mounted atop the flexible valve member within the shell. The flexible member is moveable between closed and open positions to allow the flow of fluid therethrough. The valve is engageable with a filling device having flow ports and a surrounding closure. The closure and/or the shaft is movable between (i) a first position wherein the closure closes the port(s), and (ii) a second position opening the port(s). Alternatively, the valve may comprise a portion of a female connector and the filling device may comprise a portion of a male connector to form an aseptic fluid connector for the aseptic transfer of fluid therethrough.

102. 发明申请

US20130190704A1 Device with Co-Molded Closure, One-Way Valve, Variable-Volume Storage Chamber and Anti-Spritz Feature and Related Method 有权
标题翻译：具有共模闭合装置，单向阀，可变容积储存室和抗Spritz特征及相关方法
公开(公告)号：US20130190704A1
公开(公告)日：2013-07-25
申请号：US13745721
申请日：2013-01-18
申请人： Daniel Py
发明人： Daniel Py
IPC分类号： A61F9/00 , B23P15/00
CPC分类号： A61F9/0008 , B05B11/0056 , B05B11/0062 , B05B11/0067 , B05B11/007 , B05B11/0097 , B23P15/001 , B65D83/0022 , Y10T29/49412
摘要： A device has a first part with a valve seat and storage chamber, and a second part with a flexible valve cover and actuator. The storage chamber may be formed from a pre-form blow-molded into a flexible pouch defining a variable-volume storage chamber. The flexible valve cover and valve seat form a normally closed valve seam therebetween. The valve cover is movable in response to fluid at an inlet to the seam exceeding a valve opening pressure of the one-way valve between (i) a normally closed position with valve cover and valve seat in contact with each other and defining the normally closed seam, and (ii) a second position with at least a portion of the valve cover spaced away from the valve seat to allow the fluid to pass through the seam. The one-way valve may have anti-spritz features for using the device to dispense a substance, such as to the eye. The device may contain prostaglandins without the device material absorbing the prostaglandins material and/or without the material being adsorbed into the drug.
摘要翻译：装置具有带阀座和储存室的第一部分，以及具有柔性阀盖和致动器的第二部分。存储室可以由吹塑成型的预成型形成为限定可变容积的储存室的柔性袋。柔性阀盖和阀座在其间形成常闭阀门。所述阀盖可响应于在所述接缝的入口处的流体在所述单向阀的打开压力之间（i）与阀盖的常闭位置和彼此接触的阀座之间，限定常闭接缝，和（ii）第二位置，其中阀盖的至少一部分与阀座间隔开，以允许流体穿过接缝。单向阀可以具有抗喷雾特征，用于使用该装置来分配物质，例如眼睛。该装置可以含有前列腺素，而没有装置材料吸收前列腺素材料和/或没有材料被吸收到药物中。

103. 发明授权

US08408256B2 Apparatus and method for needle filling and laser resealing 有权
标题翻译：针刺和激光重新密封的装置和方法
公开(公告)号：US08408256B2
公开(公告)日：2013-04-02
申请号：US11901467
申请日：2007-09-17
申请人： Daniel Py
发明人： Daniel Py
IPC分类号： B65B1/04
CPC分类号： B65B7/161 , B65B3/003 , B65B7/00 , B65B37/06 , B65B43/54 , B65B51/22 , B65B55/04 , B65B55/08 , B65B57/00 , B65B65/02
摘要： Apparatus for filling containers having stoppers that are penetrable for filling the containers with a substance, and thermally resealable for thermally sealing the resulting hole. A container support supports at least one such container in a substantially fixed position during filling and resealing. A manifold drivingly mounted over the container support comprises (1) a cartridge including a filling needle for penetrating the resealable stopper and introducing a substance therethrough into the container, a mount for mounting the cartridge on the manifold, and a removable cover releasably coupled to the mount for covering the filling needle during transportation, installation and/or removal of the cartridge from the manifold. The manifold includes a thermal source for heating a penetrated region of the stopper and, sealing the hole.
摘要翻译：用于填充容器的装置，所述容器具有用于用物质填充所述容器可穿透的塞子，并且可重新密封以热封所形成的孔。在填充和再密封期间，容器支撑件支撑至少一个这样的容器处于基本上固定的位置。驱动地安装在容器支架上的歧管包括（1）一个筒，其包括用于穿透可再密封塞子并将物质引入其中的填充针进入容器，用于将墨盒安装在歧管上的安装座以及可释放地联接到用于在从歧管运输，安装和/或移除墨盒的过程中覆盖填充针。歧管包括用于加热塞子的穿透区域并密封孔的热源。

104. 发明授权

US08397950B2 Device with co-extruded body and flexible inner bladder and related apparatus and method 有权
标题翻译：具有共挤出体和柔性内胆的装置及相关装置及方法
公开(公告)号：US08397950B2
公开(公告)日：2013-03-19
申请号：US12577126
申请日：2009-10-09
申请人： Daniel Py
发明人： Daniel Py
IPC分类号： B65D35/56
CPC分类号： B65D47/24 , B05B11/3028 , B29C47/0021 , B29C47/0023 , B29C47/0026 , B29C47/065 , B29C47/068 , B29C49/04 , B29L2009/00 , B29L2031/7158 , B65D23/02 , B65D47/205 , B65D47/32
摘要： A device comprises a first portion including a first polymer, and a second portion that is relatively flexible in comparison to the first portion and includes a second polymer that is substantially not bondable to the first polymer. A chamber of the device is hermetically sealable with respect to ambient atmosphere and is defined by (i) an interior of the second portion, and/or (ii) a space formed between the first and second portions. A third portion of the device includes a third polymer that is bondable to the first and second polymers and fixedly secures the first and second portions to each other.
摘要翻译：一种装置包括包含第一聚合物的第一部分和与第一部分相比具有相对柔性的第二部分，并且包括基本上不能与第一聚合物结合的第二聚合物。该装置的腔室相对于环境气氛可气密地密封，并且由（i）第二部分的内部和/或（ii）形成在第一和第二部分之间的空间限定。该装置的第三部分包括可与第一和第二聚合物结合的第三聚合物，并将第一和第二部分彼此固定地固定。

105. 发明申请

US20130015210A1 One-Way Valve and Apparatus and Method of Using the Valve 有权
标题翻译：单向阀及使用阀的设备及方法
公开(公告)号：US20130015210A1
公开(公告)日：2013-01-17
申请号：US13362532
申请日：2012-01-31
申请人： Daniel Py , Julian V. Chan , Benoit Adamo , Nathaniel Houle
发明人： Daniel Py , Julian V. Chan , Benoit Adamo , Nathaniel Houle
IPC分类号： B65D37/00
CPC分类号： B67D1/108 , B05B11/00444 , B65B39/004 , B65D51/002 , B65D51/1616 , B67D1/0004 , B67D1/0007 , B67D1/0009 , B67D1/0082 , B67D1/0801 , B67D1/10 , B67D1/1279 , B67D3/0067 , B67D3/04 , B67D2001/0827 , F04B53/1037
摘要： A flexible pouch and valve assembly is provided for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The flexible pouch and valve assembly are receivable within a relatively rigid housing, and are adapted to cooperate with a pump for pumping discrete portions of substance from the pouch and through the one-way valve to dispense the substance therefrom. The assembly comprises a flexible pouch defining therein a variable-volume storage chamber sealed with respect to the ambient atmosphere for aseptically storing therein multiple portions of the substance. A one-way valve of the assembly includes a valve body defining an axially-extending valve seat and at least one flow aperture extending through the valve body and/or the valve seat.
摘要翻译：提供了一种柔性袋和阀组件，用于无菌存储物质，从其中分配多部分储存物质，并将残留在袋中的物质保持在相对于环境大气密封的无菌状态。柔性袋和阀组件可接收在相对刚性的壳体内，并且适于与泵协作，用于泵送物质的离散部分并且通过单向阀从其分配物质。组件包括柔性袋，其中限定有相对于环境大气密封的可变容积存储室，用于将物质的多个部分无菌存储。组件的单向阀包括限定轴向延伸的阀座的阀体和延伸穿过阀体和/或阀座的至少一个流动孔。

106. 外观设计

USD668963S1 Valve and tube assembly 有权
标题翻译：阀和管总成
公开(公告)号：USD668963S1
公开(公告)日：2012-10-16
申请号：US29408266
申请日：2011-12-09
申请人： Daniel Py , Nathaniel Houle , Eric E. Hartman , Miles J. Flamenbaum
设计人： Daniel Py , Nathaniel Houle , Eric E. Hartman , Miles J. Flamenbaum

107. 外观设计

USD667947S1 Dispenser 有权
公开(公告)号：USD667947S1
公开(公告)日：2012-09-25
申请号：US29407973
申请日：2011-12-06
申请人： Daniel Py , Norbert M. Assion , Stephanie Ferreira
设计人： Daniel Py , Norbert M. Assion , Stephanie Ferreira

108. 发明申请

US20120085463A1 Device with Penetrable and Resealable Portion and Related Method 有权
标题翻译：具有可穿透和可重复部分的装置及相关方法
公开(公告)号：US20120085463A1
公开(公告)日：2012-04-12
申请号：US13326177
申请日：2011-12-14
申请人： Daniel Py
发明人： Daniel Py
IPC分类号： B65B3/00
CPC分类号： A61J1/2096 , A61J1/1406 , A61J1/1468 , A61J1/18 , A61L2/08 , B29C65/16 , B29C65/1616 , B29C65/1619 , B29C65/1654 , B29C65/1677 , B29C65/18 , B29C66/001 , B29C66/1222 , B29C66/1224 , B29C66/12461 , B29C66/1312 , B29C66/342 , B29C66/534 , B29C66/5344 , B29C66/542 , B29C66/612 , B29C66/71 , B29C66/73755 , B29C66/7392 , B29C66/73921 , B29C66/7394 , B29C66/8322 , B29C67/004 , B29L2031/7158 , B29L2031/753 , B65B3/003 , B65B7/161 , B65D51/002 , B29C65/00 , B29K2025/08 , B29K2023/00
摘要： Device and method for needle penetrating and filling a chamber with a predetermined substance, and hermetically resealing a resulting needle hole in the device by applying radiation thereto. The needle penetrable and resealable portion defines a predetermined wall thickness in an axial direction thereof, and may include a thermoplastic that substantially prevents the formation of particles released into the chamber from the needle penetrable and resealable portion during penetration by and withdrawal of the needle. Such thermoplastic may include a predetermined amount of pigment that allows the thermoplastic to substantially absorb laser radiation at a predetermined wavelength, substantially prevent the passage of radiation through the predetermined wall thickness thereof, and hermetically seal a needle aperture formed in the needle penetration region thereof in a predetermined time period.
摘要翻译：用于穿刺和填充具有预定物质的腔室的装置和方法，并且通过向其施加辐射气密地重新密封装置中的所得针孔。针穿透和可重新密封的部分在其轴向方向上限定预定的壁厚，并且可以包括热塑性材料，其基本上防止在穿透和抽出针时从针穿透和可再密封部分释放到腔中的颗粒的形成。这种热塑性材料可以包括预定量的颜料，其允许热塑性塑料基本上吸收预定波长的激光辐射，基本上防止辐射通过其预定壁厚，并将形成在其针穿入区域中的针孔气密地密封在预定时间段。

109. 外观设计

USD655621S1 Dispenser 有权
公开(公告)号：USD655621S1
公开(公告)日：2012-03-13
申请号：US29376356
申请日：2010-10-06
申请人： Daniel Py , Julian V. Chan , Luz Gladys Valencia
设计人： Daniel Py , Julian V. Chan , Luz Gladys Valencia

110. 发明授权

US08132695B2 Multiple dose delivery device with manually depressible actuator and one-way valve for storing and dispensing substances, and related method 有权
标题翻译：具有手动按压致动器和用于存储和分配物质的单向阀的多剂量输送装置及相关方法
公开(公告)号：US08132695B2
公开(公告)日：2012-03-13
申请号：US11938144
申请日：2007-11-09
申请人： Daniel Py , Beniot Adamo
发明人： Daniel Py , Beniot Adamo
IPC分类号： B65D37/00
CPC分类号： B65D83/0033 , A61F9/0008 , B05B11/0027 , B05B11/007 , B05B11/0097 , B05B11/3032 , B05B15/50 , B65D47/18
摘要： A dispenser has a body with a variable-volume storage chamber for storing substance, and a dispensing portion defining a dosage chamber in fluid communication with the storage chamber. A first valve includes a valve seat and a flexible valve cover seated thereon defining a normally-closed fluid-tight seam therebetween. The valve cover relative to moves from the valve seat to allow substance through the seam and out of the dispenser. A second valve allows substance from the storage chamber into the dosage chamber and substantially prevents flow from the dosage chamber into the storage chamber. An actuator is manually movable between (i) a first non-actuated position, and (ii) a second actuated position extending into the dosage chamber for compressing a dose of substance therein, dispensing substance through the first valve. The elasticity of the actuator causes it to return to the first non-actuated position upon manually releasing the actuator.
摘要翻译：分配器具有主体，其具有用于存储物质的可变容积的储存室，以及限定与储存室流体连通的剂量室的分配部分。第一阀包括阀座和位于其上的柔性阀盖，限定了它们之间的常闭流体密封接缝。阀盖相对于从阀座移动以允许物质通过接缝并从分配器中排出。第二阀允许物质从储存室进入剂量室，并且基本上防止从剂量室流入储存室。致动器可以在（i）第一非致动位置和（ii）延伸到剂量室中的第二致动位置之间手动地移动，用于在其中压缩一定剂量的物质，通过第一阀分配物质。当手动释放致动器时，致动器的弹性使其返回到第一非致动位置。

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