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91. 发明申请

US20230025881A1 SYSTEM FOR ULTRAFILTRATION OF BLOOD 有权
公开(公告)号：US20230025881A1
公开(公告)日：2023-01-26
申请号：US17784723
申请日：2020-10-10
申请人： GAMBRO LUNDIA AB
发明人： Christian VARTIA
IPC分类号： A61M1/34 , A61M1/36 , A61M60/279 , A61M60/113 , A61M60/441 , A61M60/37
摘要： A blood ultrafiltration system comprises a blood filter with first and second compartments separated by a semipermeable membrane. Blood input and blood output lines are connected in fluid communication with the first compartment. An effluent line is connected in fluid communication with the second compartment. A peristaltic pump is arranged for repeated engagement with first and second line segments. In a first arrangement, the first line segment is part of the blood input line or the blood output line and the second line segment is part of the effluent line. In a second arrangement, the first line segment is part of the blood input line and the second line segment is part of the blood output line. The system is operable, by the peristaltic pump, to pump blood through the blood filter and control the extraction of ultrafiltrate in the blood filter.

92. 发明申请

US20230022901A1 COMBINED BLOOD PUMP AND OXYGENATOR SYSTEM AND RELATED METHODS 有权
公开(公告)号：US20230022901A1
公开(公告)日：2023-01-26
申请号：US17895341
申请日：2022-08-25
申请人： OX MED INC.
发明人： Nidal Abi Rafeh
IPC分类号： A61M60/113 , A61M60/414 , A61M60/232 , A61M60/237 , A61M60/38 , A61M60/833 , A61M60/508
摘要： A blood pump-oxygenator system comprises at least one blood pump, an oxygenator, inflow and outflow cannulas, connected to form a closed series circuit operable as a cardiopulmonary bypass system for extracorporeal processing of the patient's blood. The blood pump conveys blood through the circuit from the patient into the inflow cannula, through the oxygenator and out of the outflow cannula back into the patient. A manifold is connected between the inflow and outflow cannulas so blood passes through the manifold, wherein the manifold accommodates the blood pump and the oxygenator to form a recirculation loop configured to recirculate at least part of the blood in the circuit so the blood passes over the oxygenator multiple times. An extra blood pump is positioned at the outflow cannula to deliver a set volume to the patient, controllable independently from the blood pump that circulates the blood in the manifold including the oxygenator.

93. 发明申请

US20230014488A1 EXTRACORPOREAL BLOOD TREATMENT METHOD 有权
公开(公告)号：US20230014488A1
公开(公告)日：2023-01-19
申请号：US17948833
申请日：2022-09-20
申请人： GAMBRO LUNDIA AB
发明人： Paolo Rovatti , Katty Ferrari
IPC分类号： A61M1/16 , A61M1/30 , A61M1/34 , A61M1/36 , A61M60/113
摘要： An extracorporeal blood treatment apparatus comprises: a blood treatment device (2) comprising a blood chamber (3) and a fluid chamber (4) separated from one another by a semipermeable membrane (5); an extracorporeal blood circuit (17) comprising a blood withdrawal line (6) connected to an inlet port (3a) of the blood chamber (3) and a blood return line (7) connected to an outlet port (3b) of the blood chamber (3); a blood pump (21) configured to be coupled to the blood withdrawal line (6); a hydraulic circuit (100) connectable to the fluid chamber (4), wherein the hydraulic circuit (100) comprises a fluid preparation device (9) connected to a water network (14) and configured to dilute concentrates in water to prepare a treatment fluid; a control unit (12) connected to the preparation device (9) and to the blood pump (21). The control unit (12) is configured to execute the following procedure: setting the hydraulic circuit (100) so that the fluid preparation device (9) bypasses the fluid chamber (4); controlling the fluid preparation device (9) to prepare the treatment fluid while bypassing the fluid chamber (4); and simultaneously controlling the blood pump (21) to perform pure ultrafiltration of a patient (P) connected to the extracorporeal blood circuit (17).

94. 发明申请

US20230001068A1 FLUID DIVERTING DEVICE FOR AN APPARATUS FOR EXTRACORPOREAL TREATMENT OF BLOOD AND BLOOD SET PROVIDED WITH SAID FLUID DIVERTING DEVICE 有权
公开(公告)号：US20230001068A1
公开(公告)日：2023-01-05
申请号：US17757266
申请日：2020-09-18
申请人： GAMBRO LUNDIA AB
发明人： Guillaume VERNIN
IPC分类号： A61M1/36 , A61M60/279 , A61M60/113 , A61M60/37 , A61M60/851
摘要： A fluid diverting device for an apparatus for extracorporeal treatment of blood is configured to be placed in-line between a main portion (22) of the apparatus (1) and a vascular access of a patient (P) and comprises: a substantially H-shaped conduits assembly comprising a withdrawal conduit (23), a return conduit (24) and at least one bridging conduit (25, 125) connecting the withdrawal conduit (23) to the return conduit (24). The withdrawal conduit (23) is connectable upstream and downstream to a withdrawal line (6) of the apparatus (1), the return conduit (24) is connectable upstream and downstream to a return line (7) of the apparatus (1). A plurality of valves (26, 27, 28, 29, 30, 32) or distributors (201, 202) operate on the withdrawal conduit (23), on the return conduit (24) and on the at least one bridging conduit (25) and are configured to divert a flow of liquid and/or blood without disconnecting the patient (P).

95. 发明授权

US11519413B2 Optimizing pumping of variable viscosities via microtextured miniaturized tesla pump 有权
公开(公告)号：US11519413B2
公开(公告)日：2022-12-06
申请号：US17285164
申请日：2019-10-14
申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN
发明人： Joe Fu-Jiou Lo
IPC分类号： F04D7/04 , F04D1/00 , F04D13/02 , F04D29/22 , F04D29/42 , A61M60/216 , A61M60/419 , A61M60/37 , A61M60/113
摘要： An integrated flow source is a limiting factor in numerous microfluidic applications. In addition to precise gradients and controlling molecular transports, a built-in source of stable and accurate flow can enable novel shear stress modulations for long-term cell culturing studies. The Tesla turbine, when used as a pump on the microfluidic regime, produces stable and accurate fluid gradients by utilizing laminar flow between its rotating discs Utilizing a stereolithography based 3D printer, a tesla pump (Ø10 cm) and associated housing capable of driving a microfluidic gradient is provided having a printed rotor surface topology of the pump in order to enhance pumping of biological fluids like blood at elevated viscosities. The surface topology is tuned via 3D pixilation, and this modulation completely recovered the pressure loss between pumping water at 1 cP versus glycerol solution at 3 cP. As a result, increased fluid viscosities, and even Non-Newtonian viscosities, can be used.

96. 发明申请

US20220347362A1 DUAL CHAMBER GAS EXCHANGER AND METHOD OF USE FOR RESPIRATORY SUPPORT 有权
公开(公告)号：US20220347362A1
公开(公告)日：2022-11-03
申请号：US17859144
申请日：2022-07-07
申请人： UNIVERSITY OF MARYLAND, BALTIMORE , BREETHE, INC.
发明人： Zhongjun WU , Bartley P. GRIFFITH , Jiafeng ZHANG , Steven J. ORWIG
IPC分类号： A61M1/16 , A61M1/36 , A61M60/113
摘要： The device of the present invention includes a dual chamber gas exchanger that is configured for increased flexibility and scalability for many clinical applications. The dual chamber oxygenator can be configured and used in various applications, such as in a heart-lung machine for cardiopulmonary support during cardiothoracic surgery, in an extracorporeal membrane oxygenation (ECMO) circuitry, as a respiratory assist device for patients with lung failure, and the like. The dual chamber gas exchanger features two sweep gas flow paths and two gas exchange membrane bundles enclosed in a housing structure with various blood flow distribution and gas distribution mechanisms. The gas exchanger includes an outer housing, an intermediate housing, two gas exchange fiber bundles, a blood inlet, a blood outlet, two gas inlets, two gas outlets, two gas distribution chambers and an optional heat exchanger.

97. 发明授权

US11464893B2 Blood reservoir with blood-handling assembly 有权
公开(公告)号：US11464893B2
公开(公告)日：2022-10-11
申请号：US16080665
申请日：2016-02-29
申请人： Sorin Group Italia S.r.l.
发明人： Clara Pandolfini , Francesco Benatti , Claudio Silvestri
IPC分类号： A61M1/36 , A61M60/113
摘要： An apparatus includes a blood-flow-management assembly shaped to define a cylindrical aperture. The blood-flow-management assembly includes a blood collector having drainage holes configured to direct blood to a guide surface positioned below the blood collector. The guide surface may further include ribs that manage blood flow along the guide surface.

98. 发明申请

US20220296799A1 PERCUTANEOUS CATHETER 有权
公开(公告)号：US20220296799A1
公开(公告)日：2022-09-22
申请号：US17834239
申请日：2022-06-07
申请人： TERUMO KABUSHIKI KAISHA
发明人： Kenji Yokoyama
IPC分类号： A61M1/36 , A61M60/113 , A61M60/232 , A61M60/38
摘要： A percutaneous catheter includes an expansion portion, a shaft portion, and an intermediate portion. The expansion portion includes a first reinforcing body including wires braided so as to intersect with each other. The shaft portion includes a second reinforcing body including the wires braided so as to intersect with each other. The intermediate portion includes a third reinforcing body including the wires braided so as to intersect with each other. The third reinforcing body is configured to have a braiding angle as an inner angle in an axial direction among angles formed by the intersecting wires which is smaller than those of the first reinforcing body and the second reinforcing body.

99. 发明申请

US20220133975A1 EXTRACORPOREAL BLOOD LINE SET AND BLOOD TREATMENT MACHINE 有权
公开(公告)号：US20220133975A1
公开(公告)日：2022-05-05
申请号：US17434045
申请日：2020-03-04
申请人： B. Braun Avitum AG
发明人： Waldemar Janik
IPC分类号： A61M1/36 , A61M60/113 , A61M60/279 , A61M60/37
摘要： An extracorporeal blood line set for a blood treatment machine or as part of a blood treatment machine, especially a dialysis machine. The extracorporeal blood line set includes an arterial blood line having a distal patient access and a proximal device port, preferably a dialyzer port, a venous blood line having a distal patient access and a proximal device port, preferably a dialyzer port, and at least one fluid supply line which is connected to the arterial and/or venous blood line(s) in at least one port section of the arterial and/or venous blood line(s) and at one end includes a container port or a fluid container. The at least one port section is in the form of a Venturi nozzle.

100. 发明授权

US11191882B2 Apparatus for extracorporeal blood treatment with automatic monitoring of respiratory rate 有权
公开(公告)号：US11191882B2
公开(公告)日：2021-12-07
申请号：US15886380
申请日：2018-02-01
申请人： B. BRAUN AVITUM AG
发明人： Günter Niemetz , Ralf Niebeling
IPC分类号： A61M1/36 , A61M60/50 , A61M60/113 , A61M60/279
摘要： An apparatus and method for extracorporeal blood treatment, especially a dialysis apparatus, are disclosed, the apparatus includes a radar sensor for monitoring a patient located at a place of treatment.

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