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91. 发明申请

US20130022662A1 COMPRESSED CHEWING GUM TABLET COMPRISING TASTE-MASKING AGENT 审中-公开
标题翻译：压克力胶片，包括吸油剂
公开(公告)号：US20130022662A1
公开(公告)日：2013-01-24
申请号：US13620169
申请日：2012-09-14
申请人： Carsten ANDERSEN , My Ly LAO
发明人： Carsten ANDERSEN , My Ly LAO
IPC分类号： A61K9/68 , A61P37/08 , A61K31/495
CPC分类号： A61K31/495 , A61K9/0058 , A61K9/209 , A61K31/496
摘要： The present invention relates to compressed chewing gum tablets comprising a useful antihistamine. In particular, the present invention is directed to compressed chewing gum tablet, which effectively mask the unpleasant tastes of compound according to formula I, such as cetirizine, contained therein and methods for preparing such compressed chewing gum tablet.
摘要翻译：本发明涉及包含有用的抗组胺剂的压缩口香糖片剂。特别地，本发明涉及压缩口香糖片剂，其有效地掩盖了包含在其中的根据式I的化合物（例如西替利嗪）的令人不愉快的味道以及制备这种压缩口香糖片剂的方法。

92. 发明申请

US20130017261A1 USE OF LACTOBACILLUS FOR TREATMENT OF VIRUS INFECTIONS 有权
标题翻译： Lactobacillus用于治疗病毒感染的应用
公开(公告)号：US20130017261A1
公开(公告)日：2013-01-17
申请号：US13619146
申请日：2012-09-14
申请人： Jan Alenfall , Anna Berggren , Carola Rask , Agnes Wold
发明人： Jan Alenfall , Anna Berggren , Carola Rask , Agnes Wold
IPC分类号： A61K35/74 , A61P31/22 , A61P31/20 , A61K9/48 , A61K9/68 , A61K9/50 , A61K9/28 , A61P31/14 , A61P31/16
CPC分类号： A23L1/3014 , A21D2/267 , A21D8/045 , A21D13/40 , A23C9/123 , A23L2/52 , A23L7/10 , A23L29/065 , A23L33/135 , A23V2002/00 , A23Y2220/73 , A61K35/747 , C12R1/225 , C12R1/25 , Y10S435/853 , Y10S435/857 , Y10S514/903 , A23V2200/3204 , A23V2200/08 , A23V2200/324
摘要： The present invention relates to the use of at least one strain of probiotic bacteria selected from Lactobacillus for the manufacture of a pharmaceutical composition for the treatment and/or prevention of a virus infection.
摘要翻译：本发明涉及至少一种选自乳杆菌属的益生菌菌株用于制造用于治疗和/或预防病毒感染的药物组合物的用途。

93. 发明授权

US08343464B2 Composition and method for treating eustachian tube dysfunction 有权
标题翻译：治疗咽鼓管功能障碍的组合物和方法
公开(公告)号：US08343464B2
公开(公告)日：2013-01-01
申请号：US13094079
申请日：2011-04-26
申请人： Phillip E. Burns
发明人： Phillip E. Burns
IPC分类号： A61K9/68
CPC分类号： A61K31/695 , A61K9/0043 , A61K9/06 , A61K33/08 , A61K47/02 , A61K47/46
摘要： A method of treating Eustachian tube dysfunction in a person includes placing the person's body in a position substantially lying on one of the person's left or right sides. The side on which the person is lying is the side affected by Eustachian tube dysfunction. A composition of simethicone in a concentration of about 0.05% to 0.65% wt/vol diluted in an aqueous carrier is introduced through the nasal cavity of the same side on which the person is lying. The simethicone composition is then allowed to coat the person's pharynx on the side of which the person is lying.
摘要翻译：治疗人的咽鼓管功能障碍的方法包括将人的身体放置在基本上位于人的左侧或右侧之一的位置。该人躺在身边的一侧是受咽鼓管功能障碍影响的一侧。在水性载体中稀释的约0.05％至0.65％wt /体积浓度的二甲硅油的组合物通过与该人所在的同一侧的鼻腔引入。然后允许二甲硅油组合物涂覆该人所躺在一旁的人的咽部。

94. 发明申请

US20120276187A1 TABLETTED CHEWING GUM SWEET 审中-公开
标题翻译：数字茶叶糖
公开(公告)号：US20120276187A1
公开(公告)日：2012-11-01
申请号：US13544082
申请日：2012-07-09
申请人： JOHN MICHAEL LEADBEATER , VICTOR HEALD , NICHOLAS ALAN COOPER
发明人： JOHN MICHAEL LEADBEATER , VICTOR HEALD , NICHOLAS ALAN COOPER
IPC分类号： A61K9/68 , A61K33/10
CPC分类号： A23G4/00 , A23G4/06 , A23G4/20
摘要： A medicated chewing gum tablet comprising at least two layers, a first layer prepared by compressing a gum base material and tablet base material, and a second layer prepared by compressing a tablet base material, wherein the second layer further comprises an active ingredient being a mineral salt, wherein the mineral is calcium.
摘要翻译：一种含有至少两层的药用口香糖片剂，通过压缩胶基材料和片剂基材料制备的第一层和通过压制片剂基材料制备的第二层，其中第二层还包含矿物质的活性成分盐，其中矿物质是钙。

95. 发明申请

US20120251462A1 Agent For Smoker Dehabituation 审中-公开
标题翻译：吸烟者居家代理
公开(公告)号：US20120251462A1
公开(公告)日：2012-10-04
申请号：US13437444
申请日：2012-04-02
申请人： Ann-Kathrin Trierweiler , Bernhard Mueller
发明人： Ann-Kathrin Trierweiler , Bernhard Mueller
IPC分类号： A61K31/216 , A61P25/34 , A61K9/68
CPC分类号： A61K36/53 , A23L33/105 , A61K9/0056 , A61K9/0058 , A61K31/216
摘要： The present invention relates to rosmarinic acid for use in a method for smoker dehabituation, wherein the rosmarinic acid is preferably in the form of a dried, aqueous extract of leaves of lemon balm (Melissa officinalis). In addition, the present invention relates to foods and food supplements for use in a method for smoker dehabituation, wherein these foods and food supplements contain rosmarinic acid, in particular rosmarinic acid in the form of a dried, aqueous extract of leaves of lemon balm (Melissa officinalis).
摘要翻译：本发明涉及用于吸烟者消养的方法中的迷迭香酸，其中迷迭香酸优选为柠檬香叶（Melissa officinalis）的干燥的含水提取物的形式。此外，本发明涉及用于吸烟者营养方法的食品和食品补充剂，其中这些食品和食品添加剂含有迷迭香酸，特别是柠檬香叶叶的干燥水性提取物形式的迷迭香酸（迷迭香酸） Melissa officinalis）。

96. 发明申请

US20120251461A1 [((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexanecarbonyl)-amino]-acetic acid isopropyl ester and related compounds and their use in therapy 有权
标题翻译： [（（1R，2S，5R）-2-异丙基-5-甲基 - 环己烷羰基） - 氨基] - 乙酸异丙酯和相关化合物及其在治疗中的用途
公开(公告)号：US20120251461A1
公开(公告)日：2012-10-04
申请号：US13065971
申请日：2011-04-04
申请人： Edward T. Wei
发明人： Edward T. Wei
IPC分类号： A61K9/68 , A61P11/06 , A61P27/02 , A61P11/00 , C07C229/28 , A61K31/24
CPC分类号： A61K9/0056 , A61K9/0048 , A61K9/2018 , A61K31/24
摘要： The present invention pertains generally to the field of coolants and medical therapy. More particularly, the present invention relates to certain anti-nociceptive agents, such as [((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexanecarbonyl)-amino]-acetic acid isopropyl ester, that are potent and long-acting and selectively cooling for non-keratinized epithelial tissues as compared to keratinized epithelial tissues, and are useful, for example, for the treatment of (e.g., the alleviation of symptoms of; the amelioration of) sensory discomfort of non-keratinized stratified epithelial (NKSE) tissue; and so for treatment of: sensory discomfort of an ocular surface, an eyelid, a margin of an eyelid, an anterior part of an eyeball, a conjunctiva, a lachrymal system, a pre-corneal film, or a cornea, a lining of the oral cavity, an internal portion of the lips, a pharyngeal surface, an esophageal surface, or an anogenital surface; eye discomfort, e.g., caused by extended wear of contact lenses, by eye strain and/or fatigue, by air pollutants, by excessive exposure to the sun, by conjunctivitis, by dry eye syndrome; sensory discomfort associated with oral mucositis; airway (e.g., larynx, trachea, and/or bronchi) tightness, discomfort in the airways (e.g., larynx, trachea, and/or bronchi), choking, cough, and/or dyspnea, e.g., associated with asthma and/or chronic obstructive pulmonary diseases (COPD).
摘要翻译：本发明一般涉及冷却剂和药物治疗领域。更具体地，本发明涉及某些抗伤害感受剂，例如[（（1R，2S，5R）-2-异丙基-5-甲基 - 环己烷羰基） - 氨基] - 乙酸异丙酯，其是有效的和长的与角质化的上皮组织相比，对非角质化上皮组织的作用和选择性冷却，并且可用于例如非角质化分层上皮的治疗（例如，减轻症状，改善）感觉不适（NKSE）组织; 因此用于治疗：眼表面，眼睑，眼睑边缘，眼球前部，结膜，泪液系统，角膜前角膜或角膜的感觉不适，口腔，嘴唇的内部，咽表面，食管表面或肛门表面; 由眼睛疲劳和/或疲劳，空气污染物，过度暴露于阳光，结膜炎，干眼综合征引起的眼睛不适; 与口腔粘膜炎相关的感觉不适; 呼吸道（例如喉，气管和/或支气管）紧张，气道不适（例如喉，气管和/或支气管），窒息，咳嗽和/或呼吸困难，例如与哮喘和/或慢性相关阻塞性肺疾病（COPD）。

97. 发明申请

US20120244201A1 PROCESS FOR THE PREPARATION OF AROMATIZED CHEWING FOAMS FOR COSMETIC PRODUCTS 审中-公开
标题翻译：用于化妆品的芳香化茶叶的制备方法
公开(公告)号：US20120244201A1
公开(公告)日：2012-09-27
申请号：US13489821
申请日：2012-06-06
申请人： Steffen HOFACKER , Meike Niesten , Thorsten Rische , Sebastian Dörr , Thorsten Krämer , Dirk Schwannecke , Gabriele Rohé , Jens Hepperle , Hartwig Kempkes , Claudia Letmathe
发明人： Steffen HOFACKER , Meike Niesten , Thorsten Rische , Sebastian Dörr , Thorsten Krämer , Dirk Schwannecke , Gabriele Rohé , Jens Hepperle , Hartwig Kempkes , Claudia Letmathe
IPC分类号： A61Q11/00 , A61K9/68 , A61K8/02
CPC分类号： A61Q11/00 , A61K8/046 , A61K8/87
摘要： The invention relates to a process for the preparation of novel aromatized chewing foams for the oral care sector based on polyurethane-polyureas and aromatizing compositions.
摘要翻译：本发明涉及一种基于聚氨酯 - 聚脲和芳构化组合物来制备用于口腔护理部门的新颖芳香化咀嚼泡沫的方法。

98. 发明申请

US20120237456A1 ORAL COMPOSITIONS CONTAINING EXTRACTS OF GARCINIA MANGOSTANA L. AND RELATED METHODS 审中-公开
标题翻译：含有GARCINIA MANGOSTANA L.提取物的口服组合物及相关方法
公开(公告)号：US20120237456A1
公开(公告)日：2012-09-20
申请号：US13513606
申请日：2010-12-01
申请人： Harsh M. Trivedi , Elizabeth K. Gittins
发明人： Harsh M. Trivedi , Elizabeth K. Gittins
IPC分类号： A61K36/38 , A61P1/02 , A61K36/53 , A61K36/575 , A61K36/45 , A61K36/82 , A61K36/9068 , A61K36/725 , A61K36/58 , A61K36/48 , A61K36/52 , A61K36/42 , A61K36/54 , A61K36/61 , A61K36/67 , A61K9/68
CPC分类号： A61K8/97 , A61K36/00 , A61K36/38 , A61K45/06 , A61K2800/92 , A61Q11/00 , A61K2300/00
摘要： Described herein are compositions comprising a combination of extracts, and methods of preparing and using the same.
摘要翻译：本文描述的是包含提取物组合的组合物，以及其制备和使用方法。

99. 发明申请

US20120237454A1 Means and Methods for Preventing and/or Treating Caries 审中-公开
标题翻译：预防和/或治疗龋齿的方法和方法
公开(公告)号：US20120237454A1
公开(公告)日：2012-09-20
申请号：US13462171
申请日：2012-05-02
申请人： Bruno Kaesler , Rolf Knöll , Mewes Boettner , Eckhard Budde , Christine Lang , Martin Ryser , Markus Veen
发明人： Bruno Kaesler , Rolf Knöll , Mewes Boettner , Eckhard Budde , Christine Lang , Martin Ryser , Markus Veen
IPC分类号： A61K8/99 , C12N1/20 , A61Q11/00 , A61P19/00 , A61K35/74 , A61K9/68
CPC分类号： A61K8/99 , A23G3/366 , A23G4/123 , A23K50/10 , A23K50/30 , A23K50/40 , A23K50/50 , A23K50/70 , A23K50/75 , A23K50/80 , A23L7/10 , A23L33/135 , A23V2002/00 , A23Y2220/63 , A23Y2220/73 , A23Y2240/49 , A61K8/0216 , A61K8/042 , A61K8/60 , A61K35/747 , A61Q11/00 , C12N1/20 , C12R1/225 , A23V2200/312 , A23V2200/3204
摘要： The present invention relates to a microorganism belonging to the group of lactic acid bacteria capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; (ii) resistant to protease treatment; (iii) calcium-dependent; (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. The present invention is also relates to an analog or fragment of the microorganism which is thermally inactivated or lyophilized, wherein the analog or fragment retains the capability of specifically binding to Streptococcus mutans. The invention further encompasses compositions and additives for food, feed or drinks comprising the microorganism or an analog or fragment thereof. Also provided is uses of the microorganism or an analog or fragment thereof for the preparation of an anticariogenic or pharmaceutical composition or anticariogenic food or feedstuff as well as methods for producing the compositions or food or feedstuff.
摘要翻译：本发明涉及能够特异性结合变形链球菌的乳酸菌群的微生物，其特异性结合是（i）耐热处理; （ii）耐蛋白酶处理; （iii）钙依赖性; （iv）在4.5至8.5之间的pH范围内形成; 和/或（v）在唾液存在下形成。本发明还涉及热灭活或冻干的微生物类似物或片段，其中所述类似物或片段保留特异性结合变形链球菌的能力。本发明还包括包含微生物或其类似物或片段的食品，饲料或饮料的组合物和添加剂。还提供了微生物或其类似物或片段在制备抗焦虑或药物组合物或抗癌食品或饲料中的用途以及用于生产组合物或食物或饲料的方法。

100. 发明授权

US08268292B2 Obovatol having anti-anxiety activity 有权
标题翻译： Obovatol具有抗焦虑活性
公开(公告)号：US08268292B2
公开(公告)日：2012-09-18
申请号：US11913734
申请日：2006-05-04
申请人： Byoung Mog Kwon , Seung Ho Lee , Kwang Hee Son , Jin Tae Hong , Ki Wan Oh , Jeong Ju Seo
发明人： Byoung Mog Kwon , Seung Ho Lee , Kwang Hee Son , Jin Tae Hong , Ki Wan Oh , Jeong Ju Seo
IPC分类号： A61K9/68 , A61K31/075 , A01N31/14
CPC分类号： A61K31/085
摘要： The present invention relates to obovatol compound isolated from Magnolia obovata Thunb. for the prevention and treatment of anxiety disorders involved with CNS. The obovatol compound isolated from Magnolia obovata Thunb. have potent anti-anxiety activity, verified by an increased percentage of time on the open arms, an increased number of entries into, time spent on, the distal portion of the open arms, and a decreased activity of locomotor. Therefore it can be used as the therapeutics or health care food for treating and preventing anxiety disorders.
摘要翻译：本发明涉及从玉兰木本中分离出来的浮选酚化合物。用于预防和治疗与CNS相关的焦虑症。从木兰云母Thunb分离的obovatol化合物。具有强大的抗焦虑活动，通过开放武器时间的增加，开放武器的远端部分的进入，花费的时间增加以及运动员的活动减少来证实。因此，它可以用作治疗和预防焦虑症的治疗剂或保健食品。

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