会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 92. 发明授权
    • Process for the production of water-adsorbing but water-insoluble
cellulose ethers
    • 用于生产水吸附但水不溶性纤维素醚的方法
    • US3965091A
    • 1976-06-22
    • US524822
    • 1974-11-18
    • Arno HolstHelmut Lask
    • Arno HolstHelmut Lask
    • C08B11/187A61L15/28C08B11/14C08B11/193C08B15/10C08B11/00C08B11/20
    • C08B15/10A61L15/28C08B11/14C08B11/193
    • This invention relates to an improvement in the process for the production of water-adsorbing, but largely water-insoluble, cellulose ethers, in which cellulose is alkalized in the presence of alkali and isopropanol as a reaction medium and is so reacted with an etherification agent that by etherification only a water-soluble cellulose ether is produced, and in which process a modification agent which is able to react with the still free hydroxyl groups of the cellulose anhydro glucose groups in an alkaline reaction medium is reacted before, during, or after the etherification, the improvement comprising effecting the etherification of cellulose to carboxymethyl cellulose, carboxymethyl hydroxyethyl cellulose, hydroxyethyl cellulose, or methylhydroxyethyl cellulose, reacting with the modification agent in the presence of 0.8 to 7.5 parts by weight of isopropanol, based upon the cellulose weight, and employing a modification agent being one of the formulae ##EQU1## R.sub.1 in formula I being hydroxyl, or an acylamino or etherified carbamino group, and R.sub.2 in formula I being hydrogen or a carboxyl group.
    • 本发明涉及在碱和异丙醇作为反应介质存在下使纤维素碱化的水吸附,但主要是水不溶性纤维素醚的方法的改进,并且与醚化剂 通过醚化仅产生水溶性纤维素醚,并且在该方法中,能够在碱性反应介质中与纤维素脱氢葡萄糖基团的游离羟基反应的改性剂在之前,之中或之后反应 醚化,改进包括将纤维素醚化为羧甲基纤维素,羧甲基羟乙基纤维素,羟乙基纤维素或甲基羟乙基纤维素,在0.8至7.5重量份异丙醇存在下,基于纤维素重量与改性剂反应, 并且使用改性剂为下式之一:HOHH H | PARALLEL || |(I) H 2 C = C-C-N-C-R 1和(II)H 2 C = C-SO 2 -NH 2,式I中的R 2 R为羟基,或酰基氨基或醚化的氨基氨基,式I中的R 2为氢或羧基。
    • 93. 发明授权
    • Composition containing gel
    • 含有凝胶的组合物
    • US3640741A
    • 1972-02-08
    • US3640741D
    • 1970-02-24
    • HOLLISTER INC
    • ETES DONALD E
    • A61K8/34A61K8/73A61K47/36A61K47/38A61L15/28A61L15/64A61L24/08A61Q19/00C08B11/20C08B15/10C08B37/12C08B19/10C08B21/30C08B21/32
    • A61K8/042A61K8/345A61K8/73A61K8/731A61K8/733A61K9/0014A61K47/36A61K47/38A61K2800/5424A61L15/28A61L15/64A61L24/08A61L2400/14A61Q19/00C08B11/20C08B15/10C08B31/003C08B37/0084Y10S514/944
    • A new plastic composition which is slow dissolving in aqueous media and can be used to slowly release medication or other additive ingredients in an aqueous environment, which plastic composition is prepared by cross-linking a hydrophilic colloid such as carboxymethyl cellulose gum or alginate gum with a crosslinking agent, usually a polyol such as propylene glycol, in a relatively nonreactive water soluble carrier such as glycerol. The total composition, including the carrier, sets up into a plastic gel, the consistency of which can be varied by varying proportions of ingredients. The reaction can be speeded or driven to a more completely cross-linked state by using a catalysts such as aluminum or calcium salts. Complexing agents can be included for complexing the catalysts and releasing it slowly throughout the reaction to slow the reaction down where desired. Generally, the reaction proceeds faster in a close to neutral or basic medium at pH''s ranging up to 10 or 11 and slower in an acid medium at pH of 5 and below so the rate of reaction can be controlled by adjusting the pH. Usually the composition will contain medication or cosmetic additives or ingredients and it can be molded by extrusion or the like into any predetermined form, e.g., in the form of a ring. In a preferred form, the composition has excellent pressure sensitive adhesive properties and these properties are very pronounced where the hydrophilic colloid used is carboxymethyl cellulose.
    • 一种新的塑料组合物,其在水性介质中缓慢溶解,可用于在水性环境中缓慢释放药物或其他添加剂成分,该塑料组合物通过将亲水胶体如羧甲基纤维素胶或藻酸盐胶与 交联剂,通常为多元醇如丙二醇,在相对非反应性的水溶性载体如甘油中。 包括载体在内的总组合物设置成塑料凝胶,其一致性可以通过不同比例的成分而变化。 反应可以通过使用诸如铝或钙盐的催化剂加速或驱动至更完全交联的状态。 可以包括络合剂以络合催化剂并在整个反应中缓慢释放催化剂,以在需要时将反应减慢。 通常,反应在接近中性或碱性介质的pH范围达到10或11,并且在pH5或更低的酸性介质中进行得更快,反应速度可以通过调节pH来控制。 通常,组合物将含有药物或化妆品添加剂或成分,并且其可以通过挤出等模制成任何预定形式,例如以环的形式。 在优选的形式中,组合物具有优异的压敏粘合剂性能,并且这些性质在使用的亲水胶体是羧甲基纤维素时非常显着。