专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

91. 发明申请

US20170303980A1 Natural Polymer-Based Porous Orthopedic Fixation Screw for Bone Repair and Regeneration 审中-公开
公开(公告)号：US20170303980A1
公开(公告)日：2017-10-26
申请号：US15649044
申请日：2017-07-13
申请人： University of Connecticut
发明人： Sangamesh G. Kumbar , Cato T. Laurencin
IPC分类号： A61B17/86 , A61L31/04 , A61L31/12 , B29C39/02 , B29C39/38 , B29C67/04 , B29C67/24 , B29L31/00 , A61B17/00 , B29K1/00 , B29K105/00
CPC分类号： A61B17/866 , A61B2017/00004 , A61B2017/00526 , A61L31/042 , A61L31/125 , B29C39/02 , B29C39/38 , B29C67/04 , B29C67/24 , B29K2001/08 , B29K2001/12 , B29K2005/00 , B29K2105/251 , B29L2031/7546
摘要： A bone fixation device made of polysaccharide particles or microspheres fused into a solid structure is provided herein. The bone fixation device may be in the form of an orthopedic screw, orthopedic pin, or orthopedic plate. Methods of making the bone fixation devices described herein are provided as are methods of treating patients in need of bone repair or replacement by implanting a bone fixation device described herein in the patient at a site of bone damage, ligament damage, or bone deformity.

92. 发明申请

US20170232158A1 ROD SHAPED BODY AND MEDICAL DEVICE 审中-公开
公开(公告)号：US20170232158A1
公开(公告)日：2017-08-17
申请号：US15586155
申请日：2017-05-03
申请人： MARVIS INTERVENTIONAL GMBH
发明人： Klaus Düring , Joachim Georg Pfeffer
IPC分类号： A61L31/12 , A61L31/14 , A61L29/12 , A61L29/02 , A61B10/02 , A61L31/04 , A61L29/04 , A61M25/09 , A61M5/32 , A61L31/02 , A61L29/14
CPC分类号： A61L31/128 , A61B10/0233 , A61L29/02 , A61L29/049 , A61L29/126 , A61L29/14 , A61L29/18 , A61L31/022 , A61L31/041 , A61L31/125 , A61L31/14 , A61L31/18 , A61M5/32 , A61M25/09 , A61M2025/09166 , A61M2025/09191 , Y10T428/2933 , Y10T428/2964 , Y10T428/2969
摘要： The present invention relates to a medical device. In particular, the present invention concerns a medical device which can be detected by means of magnetic resonance imaging (MRI).

93. 发明授权

US09656004B2 Rod shaped body and medical device 有权
公开(公告)号：US09656004B2
公开(公告)日：2017-05-23
申请号：US13880032
申请日：2011-10-18
申请人： Klaus Duering , Joachim Georg Pfeffer
发明人： Klaus Duering , Joachim Georg Pfeffer
IPC分类号： A61M25/09 , A61L31/18 , A61L29/12 , A61L29/18 , A61L31/12
CPC分类号： A61L31/128 , A61B10/0233 , A61L29/02 , A61L29/049 , A61L29/126 , A61L29/14 , A61L29/18 , A61L31/022 , A61L31/041 , A61L31/125 , A61L31/14 , A61L31/18 , A61M5/32 , A61M25/09 , A61M2025/09166 , A61M2025/09191 , Y10T428/2933 , Y10T428/2964 , Y10T428/2969
摘要： The present invention relates to a medical device. In particular, the present invention concerns a medical device which can be detected by means of magnetic resonance imaging (MRI).

94. 发明申请

US20160339143A1 Modified Starch Material of Biocompatible Hemostasis 审中-公开
公开(公告)号：US20160339143A1
公开(公告)日：2016-11-24
申请号：US15229080
申请日：2016-08-04
申请人： Xin Ji
发明人： Xin Ji
IPC分类号： A61L24/08 , A61K9/14 , A61K31/718
CPC分类号： A61L31/042 , A61K9/0014 , A61K9/14 , A61K9/19 , A61K31/718 , A61K31/738 , A61K45/06 , A61L24/0015 , A61L24/0036 , A61L24/0073 , A61L24/08 , A61L24/104 , A61L26/0023 , A61L26/0085 , A61L31/045 , A61L31/125 , A61L2300/406 , A61L2400/04 , A61L2430/34 , C08B30/00 , C08B30/20 , C08B31/00 , C08B31/003 , C08B31/02 , C08B31/04 , C08B31/08 , C08B31/10 , C08B31/12 , C08B31/16 , C08B31/18 , C08B33/02 , C08B33/04 , C08B33/06 , C08B35/02 , C08B35/04 , C08B35/06 , C08L3/04 , C08L3/18 , C08L89/06 , Y10T428/2982
摘要： A modified starch material is arranged for biocompatible hemostasis, biocompatible adhesion prevention, tissue healing promotion, absorbable surgical wound sealing and tissue bonding, when applied as a biocompatible modified starch to the tissue of animals. The modified starch material produces hemostasis, reduces bleeding of the wound, extravasation of blood and tissue exudation, preserves the wound surface or the wound in relative wetness or dryness, inhibits the growth of bacteria and inflammatory response, minimizes tissue inflammation, and relieves patient pain. Any excess modified starch not involved in hemostatic activity is readily dissolved and rinsed away through saline irrigation during operation. After treatment of surgical wounds, combat wounds, trauma and emergency wounds, the modified starch hemostatic material is rapidly absorbed by the body without the complications associated with gauze and bandage removal.

95. 发明授权

US09439790B2 Stent with anti-migration feature 有权
标题翻译：支架具有抗迁移功能
公开(公告)号：US09439790B2
公开(公告)日：2016-09-13
申请号：US12354392
申请日：2009-01-15
申请人： Claude Clerc , Sri Tupil
发明人： Claude Clerc , Sri Tupil
IPC分类号： A61F2/848 , A61F2/07 , A61F2/90 , A61L31/10 , A61L31/12 , A61L31/14 , A61F2/30
CPC分类号： A61F2/848 , A61F2/07 , A61F2/90 , A61F2002/072 , A61F2002/075 , A61F2002/30322 , A61F2002/8486 , A61F2220/0016 , A61F2230/005 , A61F2230/0078 , A61F2250/0026 , A61F2250/0037 , A61F2250/0039 , A61L31/10 , A61L31/125 , A61L31/14
摘要： An intraluminal prosthesis includes an outer three-dimensional (3D) anti-migration structure that is attached to the outer wall of a fully covered or partially covered stent to prevent migration and still allow stent removal at a later period of time. A method of manufacturing the intraluminal prosthesis includes attaching the anti-migration structure by usage of a polymer such as polyurethane.
摘要翻译：腔内假体包括外部三维（3D）抗迁移结构，其连接到完全覆盖或部分覆盖的支架的外壁以防止迁移并且仍允许在稍后时期的支架移除。制造腔内假体的方法包括通过使用诸如聚氨酯的聚合物来附接抗迁移结构。

96. 发明申请

US20160008046A1 Natural Polymer-Based Porous Orthopedic Fixation Screw for Bone Repair and Regeneration 审中-公开
标题翻译：用于骨修复和再生的天然聚合物多孔整形固定螺钉
公开(公告)号：US20160008046A1
公开(公告)日：2016-01-14
申请号：US14859908
申请日：2015-09-21
申请人： University of Connecticut through its Center for Science & Technology Commercialization
发明人： Sangamesh G. Kumbar , Cato T. Laurencin
IPC分类号： A61B17/86 , B29C39/02 , B29C39/38 , A61L31/04
CPC分类号： A61B17/866 , A61B2017/00004 , A61B2017/00526 , A61L31/042 , A61L31/125 , B29C39/02 , B29C39/38 , B29C67/04 , B29C67/24 , B29K2001/08 , B29K2001/12 , B29K2005/00 , B29K2105/251 , B29L2031/7546
摘要： A bone fixation device made of polysaccharide particles or microspheres fused into a solid structure is provided herein. The bone fixation device may be in the form of an orthopedic screw, orthopedic pin, or orthopedic plate. Methods of making the bone fixation devices described herein are provided as are methods of treating patients in need of bone repair or replacement by implanting a bone fixation device described herein in the patient at a site of bone damage, ligament damage, or bone deformity.
摘要翻译：本发明提供一种由固体结构融合的多糖粒子或微球体构成的骨固定装置。骨固定装置可以是矫形螺钉，矫形针或矫形板的形式。提供制造本文所述的骨固定装置的方法是通过在骨损伤，韧带损伤或骨畸形的部位植入本文所述的骨固定装置来治疗需要骨修复或置换的患者的方法。

97. 发明申请

US20150352263A1 MEDICAL DEVICE WITH COATING THAT PROMOTES ENDOTHELIAL CELL ADHERENCE 审中-公开
标题翻译：具有促进内皮细胞粘附的涂层的医疗装置
公开(公告)号：US20150352263A1
公开(公告)日：2015-12-10
申请号：US14831956
申请日：2015-08-21
申请人： ORBUSNEICH MEDICAL INC.
发明人： Michael John Bradley Kutryk , Robert John Cottone, JR. , Stephen Maxwell Rowland
IPC分类号： A61L31/10 , A61L31/14 , A61F2/24 , A61L31/16
CPC分类号： A61L31/10 , A61F2/07 , A61F2/2412 , A61F2/82 , A61K38/363 , A61K38/39 , A61K39/39558 , A61L27/08 , A61L27/227 , A61L27/303 , A61L27/44 , A61L27/54 , A61L29/103 , A61L29/126 , A61L29/16 , A61L31/022 , A61L31/047 , A61L31/084 , A61L31/125 , A61L31/148 , A61L31/16 , A61L2300/256 , A61L2300/416 , A61L2300/422 , A61L2300/432 , A61L2300/606 , A61L2420/04 , B82Y30/00 , C07K16/2896 , C07K2317/55 , C12N5/0692 , C12N2510/00 , A61K2300/00
摘要： The invention relates to a method for healing blood vessels by stimulating the formation of a confluent endothelial autologous cell layer in vivo on an implantable metallic stent having a lumen and a luminal surface, and an exterior surface. More specifically, the method includes implanting the stent with a coating in a patient in need of thereof; wherein the coating includes one or more layers of a matrix covalently adherent on said luminal and exterior surface of said stent containing one or more pharmaceutical substances on said exterior surface and a therapeutically effective amount of a single type of antibody, antibody fragments or combinations thereof being compatible to binding selectively to a specific cell surface antigen of circulating autologous endothelial progenitor cells in peripheral blood. In addition, genetically engineered endothelial progenitor cells can be captured on said luminal surface of stent in vivo, to proliferate to form rapidly a confluent endothelium in situ.
摘要翻译：本发明涉及一种通过在具有内腔和内腔表面以及外表面的可植入金属支架上体内融合内皮自体细胞层的形成来治愈血管的方法。更具体地，该方法包括在需要其的患者体内植入具有涂层的支架; 其中所述涂层包括一层或多层共价粘附在所述支架的所述管腔和外表面上的基质，其在所述外表面上含有一种或多种药物物质，治疗有效量的单一类型抗体，抗体片段或其组合为与外周血中循环的自体内皮祖细胞的特异性细胞表面抗原有选择性结合。此外，遗传工程化的内皮祖细胞可以在体内在支架的所述腔表面上捕获，以增殖以迅速形成原位融合的内皮。

98. 发明申请

US20150245783A1 ROD-SHAPED BODY 审中-公开
标题翻译： ROD形状的身体
公开(公告)号：US20150245783A1
公开(公告)日：2015-09-03
申请号：US14710734
申请日：2015-05-13
申请人： MARVIS MEDICAL GMBH
发明人： JOACHIM-GEORG PFEFFER , ROLF W. GÜNTHER , THOMAS SCHMITZ RODE
IPC分类号： A61B5/055 , A61L31/02 , A61L31/04 , A61M25/09
CPC分类号： A61B5/055 , A61L29/126 , A61L29/18 , A61L31/026 , A61L31/048 , A61L31/125 , A61L31/18 , A61M25/09 , A61M2025/09133
摘要： The invention relates to a rod-shaped body (1) comprised of one or more filaments (2) and of a non-ferromagnetic matrix material (3). The matrix material (3) surrounds the filament(s) (1) and/or adheres them to one another. The rod-shaped body is also comprised of a dopant consisting of particles that generate magnetic resonance tomographic artifacts that is introduced into the matrix material (3). Rod-shaped bodies of this type can be used to construct guide wires, catheters and other instruments to be used in minimally invasive surgical interventions.
摘要翻译：本发明涉及由一根或多根细丝（2）和非铁磁性基质材料（3）组成的棒状体（1）。基质材料（3）围绕细丝（1）和/或将它们粘合在一起。棒状体还包括由引入到基质材料（3）中的产生磁共振断层摄影伪像的颗粒组成的掺杂剂。这种类型的杆状体可用于构造用于微创外科手术的导丝，导管和其他仪器。

99. 发明授权

US09066853B2 Clonidine compounds in a biodegradable fiber 有权
标题翻译：可降解纤维中的可乐定化合物
公开(公告)号：US09066853B2
公开(公告)日：2015-06-30
申请号：US13741475
申请日：2013-01-15
申请人： Warsaw Orthopedic, Inc.
发明人： Danielle L. Clay
IPC分类号： A61B17/06 , A61B17/068 , A61B17/00 , A61K9/00 , A61B17/04 , A61K47/34 , A61K9/70 , A61K31/4168 , A61B17/11
CPC分类号： A61L31/16 , A61B17/04 , A61B17/06166 , A61B17/1128 , A61B2017/00893 , A61K9/0024 , A61K9/70 , A61K31/4168 , A61K47/34 , A61L17/005 , A61L17/12 , A61L27/18 , A61L27/54 , A61L27/58 , A61L31/08 , A61L31/125 , A61L31/148 , A61L2300/204 , A61L2300/402 , A61L2300/602 , A61L2300/604 , A61L2300/606 , A61L2400/16
摘要： Effective treatments of pain for extended periods of time are provided. Through the administration of an effective amount of clonidine in a fiber at or near a target site, one can relieve pain caused by diverse sources, including but not limited to spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discogenic back pain and joint pain, as well as pain that is incidental to surgery. When appropriate fiber formulations are provided within biodegradable polymers, this pain relief can be continued for at least three days.
摘要翻译：提供长时间有效的疼痛治疗。通过在目标部位或其附近的纤维中施用有效量的可乐定，可以减轻由多种来源引起的疼痛，包括但不限于脊椎椎间盘突出症（即坐骨神经痛），脊椎脱位，狭窄，椎间盘背痛和关节疼痛，以及手术附带的疼痛。当在可生物降解的聚合物内提供合适的纤维制剂时，该疼痛缓解可持续至少三天。

100. 发明申请

US20140369954A1 D, L-CYCLIC PEPTIDE NANOTUBE REINFORCING AGENTS 有权
标题翻译： D，L循环肽纳米粒子增强剂
公开(公告)号：US20140369954A1
公开(公告)日：2014-12-18
申请号：US14360851
申请日：2012-11-26
申请人： Neel Satish Joshi , Daniel James Rubin
发明人： Neel Satish Joshi , Daniel James Rubin
IPC分类号： A61L27/22 , A61L27/26 , D01D5/00 , A61L27/44
CPC分类号： A61L27/227 , A61K9/0092 , A61K47/42 , A61L27/18 , A61L27/26 , A61L27/44 , A61L31/125 , A61L31/129 , A61L2400/12 , A61L2430/02 , A61L2430/10 , A61L2430/34 , A61L2430/38 , B82Y30/00 , B82Y40/00 , C08K7/22 , C08K2201/011 , C08L1/02 , C08L5/04 , C08L5/08 , C08L89/00 , D01D5/0053 , D10B2331/041 , Y10T428/249921 , C08L67/04 , C08L101/16
摘要： The disclosed subject matter can provide a nanotube-reinforced polymer composite material comprising a plurality of nanotubes, each nanotube being formed of a plurality of cyclic peptide molecules, disposed within a polymer matrix, such as a biodegradable polymer matrix. A cyclic polymer, such as a cyclic 8-mer, composed of amino acid residues of alternating absolute configurations (D/L, R/S), can self-assemble into nanotubes useful for preparation of the composite polymer material of the invention. For example, the cyclic peptide (QL)4, wherein the glutamine and leucine residues are of opposite absolute configuration, self-assembles into nanotubes, which when formed into a reinforced polymer composite including poly(caprolactone), provides a biocompatible material of greater tensile strength and Young's modulus compared to the poly(caprolactone) material alone. The nanotubes can be prepared by a vapor equilibration technique or by a solvent-nonsolvent precipitation technique. The materials of the invention can be used for implants, stents and the like as well as for synthetic ligaments, tendons, cartilage, and bone for use in the living tissue of a patient in need thereof. For example, a spinal fusion cage comprising a PDLLA polymer matrix with a plurality of nanotubes of the invention can exhibit enhanced stiffness.
摘要翻译：所公开的主题可以提供包含多个纳米管的纳米管增强聚合物复合材料，每个纳米管由多个环状肽分子形成，设置在聚合物基质例如可生物降解的聚合物基质内。由交替绝对构型（D / L，R / S）的氨基酸残基组成的环状聚合物如环状8-聚体可以自组装成可用于制备本发明的复合聚合物材料的纳米管。例如，其中谷氨酰胺和亮氨酸残基具有相反绝对构型的环肽（QL）4自组装成纳米管，当其形成包含聚（己内酯）的增强聚合物复合物时，其提供了更大拉伸的生物相容性材料强度和杨氏模量与单独的聚（己内酯）材料相比。纳米管可以通过蒸汽平衡技术或溶剂 - 非溶剂沉淀技术制备。本发明的材料可用于植入物，支架等，以及用于需要其的患者的生物体组织中的合成韧带，腱，软骨和骨骼。例如，包含具有本发明的多个纳米管的PDLLA聚合物基质的脊柱融合器可以表现出增强的刚度。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式