专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

91. 发明授权

US08563534B2 Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis 有权
公开(公告)号：US08563534B2
公开(公告)日：2013-10-22
申请号：US13431262
申请日：2012-03-27
申请人： Dror Harats , Jacob George , Gideon Halperin , Niva Yacov , Eti Kovalevski-Ishai
发明人： Dror Harats , Jacob George , Gideon Halperin , Niva Yacov , Eti Kovalevski-Ishai
IPC分类号： A61K31/66
CPC分类号： C07F9/106 , A61K31/075 , A61K31/08 , A61K31/11 , A61K31/19 , A61K31/20 , A61K31/215 , A61K31/225 , A61K31/24 , A61K31/685 , C07C43/13 , C07C43/1785 , C07C43/1787 , C07F9/10 , Y02A50/411 , Y02A50/414
摘要： Novel synthetic forms of etherified oxidized phospholipids and methods of utilizing same for preventing and treating atherosclerosis and other related disorders, as well as inflammatory disorders, immune mediated diseases, autoimmune diseases and proliferative disorders, are provided. In addition, methods of synthesizing etherified and esterified oxidized phospholipids and of using same for preventing and treating atherosclerosis and other related disorders are also provided.

92. 发明授权

US08557265B2 Use of a synergistic composition as a therapeutic agent of disinfectant 有权
标题翻译：使用协同组合物作为消毒剂的治疗剂
公开(公告)号：US08557265B2
公开(公告)日：2013-10-15
申请号：US12452295
申请日：2008-06-27
申请人： Barbara Krug , Sven Eggerstedt , Christiane Ostermeyer , Thomas Lisowsky , Karlheinz Esser , Frank Büger , Richard Bloss
发明人： Barbara Krug , Sven Eggerstedt , Christiane Ostermeyer , Thomas Lisowsky , Karlheinz Esser , Frank Büger , Richard Bloss
IPC分类号： A01N25/00 , A01N25/02 , A01N59/00 , A61K9/12
CPC分类号： A61K31/352 , A01N59/00 , A61K9/0014 , A61K31/24 , A61K33/00 , A61K45/06 , A01N25/30 , A01N2300/00 , A61K2300/00
摘要： The invention relates to the use of a composition comprising a vitamin, a metal ion, and a surfactant, as a therapeutic agent or disinfectant. The composition has been known as a decontaminant because the same efficiently decomposes DNA. It has now been possible to demonstrate that the agent has surprisingly good compatibility while having a wide-ranging disinfecting effect and is therefore also suitable for other purposes, e.g., for disinfecting or dressing wounds.
摘要翻译：本发明涉及包含维生素，金属离子和表面活性剂的组合物作为治疗剂或消毒剂的用途。该组合物已知为净化剂，因为同样有效地分解DNA。现在可以证明该试剂具有惊人的良好的相容性，同时具有广泛的消毒作用，因此也适用于其它目的，例如消毒或敷料伤口。

93. 发明申请

US20130225531A1 METHOD AND COMPOSITION FOR TREATING ALZHEIMER'S DISEASE AND DEMENTIAS OF VASCULAR ORIGIN 审中-公开
标题翻译：治疗阿尔茨海默病和血管原发病的方法和组合
公开(公告)号：US20130225531A1
公开(公告)日：2013-08-29
申请号：US13720303
申请日：2012-12-19
申请人： The Board Of Trustees Of The University of Illinois
发明人： Anil Gulati
IPC分类号： A61K31/422 , A61K31/505 , A61K31/42 , A61K31/36 , A61K31/365 , A61K31/5415 , A61K31/4025 , A61K31/4155 , A61K31/497 , A61K31/4965 , A61K31/4178 , A61K31/4709 , A61K31/404 , A61K31/381 , A61K31/435 , A61K31/473 , A61K31/662 , A61K31/27 , A61K31/55 , A61K31/40 , A61K31/498 , A61K31/683
CPC分类号： A61K31/422 , A61K31/00 , A61K31/198 , A61K31/24 , A61K31/27 , A61K31/36 , A61K31/365 , A61K31/381 , A61K31/40 , A61K31/4025 , A61K31/404 , A61K31/405 , A61K31/415 , A61K31/4155 , A61K31/4178 , A61K31/42 , A61K31/426 , A61K31/433 , A61K31/435 , A61K31/4355 , A61K31/4422 , A61K31/4439 , A61K31/4465 , A61K31/454 , A61K31/4709 , A61K31/4725 , A61K31/473 , A61K31/496 , A61K31/4965 , A61K31/497 , A61K31/498 , A61K31/50 , A61K31/501 , A61K31/505 , A61K31/506 , A61K31/519 , A61K31/5415 , A61K31/55 , A61K31/662 , A61K31/664 , A61K31/683 , A61K45/06 , A61K2300/00
摘要： A composition and method of treating Alzheimer's disease or a dementia of vascular origin are disclosed. The composition and method utilize an endothelin antagonist as the active agent to treat Alzheimer's disease or a dementia of vascular origin in mammals, including humans.
摘要翻译：公开了治疗阿尔茨海默病或血管起源性痴呆的组合物和方法。组合物和方法利用内皮素拮抗剂作为活性剂来治疗哺乳动物（包括人）中的阿尔茨海默病或血管起源性痴呆。

94. 发明申请

US20130217741A1 TOPICAL PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF SKIN DAMAGE 审中-公开
标题翻译：用于治疗皮肤损伤的局部药物组合物
公开(公告)号：US20130217741A1
公开(公告)日：2013-08-22
申请号：US13834281
申请日：2013-03-15
申请人： S.L.A. PHARMA AG
发明人： DAVID NIGEL ARMSTRONG , JUSTIN SLAGEL
IPC分类号： A61K47/06 , A61K47/44
CPC分类号： A61K31/4164 , A61K9/0014 , A61K9/0031 , A61K9/06 , A61K31/192 , A61K31/24 , A61K31/245 , A61K31/355 , A61K31/407 , A61K31/4166 , A61K31/545 , A61K31/573 , A61K31/60 , A61K31/65 , A61K33/30 , A61K45/06 , A61K47/06 , A61K47/44 , A61K2300/00
摘要： A topical composition comprising about 5 wt % to about 12.5 wt % of metronidazole or a pharmacologically acceptable salt thereof in a non-aqueous vehicle. The composition may be used in the treatment of skin damage due to inflammatory skin conditions; thermal, chemical or electrical burns; infections or radiation treatment. One advantage of the composition is that topical administration of metronidazole results in a primarily local effect, and thus, side effects observed from systemic administration are avoided.
摘要翻译：包含约5wt％至约12.5wt％的甲硝唑或其药理学上可接受的盐在非水性载体中的局部组合物。该组合物可用于治疗由于炎性皮肤病症引起的皮肤损伤; 热，化学或电烧伤; 感染或放射治疗。组合物的一个优点是局部施用甲硝唑导致主要的局部作用，因此避免了从全身给药观察到的副作用。

95. 发明申请

US20130156816A1 METHODS AND COMPOSITIONS FOR USE IN AQUACULTURE 审中-公开
标题翻译：用于水产养殖的方法和组合物
公开(公告)号：US20130156816A1
公开(公告)日：2013-06-20
申请号：US13579813
申请日：2011-02-18
申请人： Larry Arthur Stobbs , James Gary Nickerson , Clayton Paul Dick
发明人： Larry Arthur Stobbs , James Gary Nickerson , Clayton Paul Dick
IPC分类号： A61K31/045 , A61K31/24 , A61K31/65 , A61K31/165 , A61K31/7008 , A61K31/546 , A61K31/496 , A61K31/341 , A61K31/505 , A61K31/17 , A61K31/4184 , A61K31/115 , A61K31/429 , A61K31/4168 , A61K31/4985 , A61K31/662 , A61K31/085
CPC分类号： A61K31/015 , A23K20/10 , A23K20/179 , A23K50/80 , A61K9/0056 , A61K9/007 , A61K9/1075 , A61K9/14 , A61K9/50 , A61K9/5015 , A61K9/5036 , A61K9/5057 , A61K31/00 , A61K31/045 , A61K31/05 , A61K31/085 , A61K31/115 , A61K31/12 , A61K31/165 , A61K31/17 , A61K31/24 , A61K31/245 , A61K31/341 , A61K31/345 , A61K31/4164 , A61K31/4168 , A61K31/4184 , A61K31/429 , A61K31/496 , A61K31/4985 , A61K31/505 , A61K31/546 , A61K31/65 , A61K31/662 , A61K31/7008 , A61K31/7036 , A61K45/06 , A61K2300/00
摘要： The invention features compositions, methods, and kits for the administration of an oxidatively transformed carotenoid, or a fractionated component thereof, for use in aquaculture.
摘要翻译：本发明的特征在于用于施用用于水产养殖的氧化转化的类胡萝卜素或其分馏组分的组合物，方法和试剂盒。

96. 发明申请

US20130150442A1 OLIGO-BENZAMIDE COMPOUNDS AND THEIR USE IN TREATING CANCERS 有权
标题翻译： OLIGO-BENZAMIDE化合物及其在治疗癌症中的应用
公开(公告)号：US20130150442A1
公开(公告)日：2013-06-13
申请号：US13683932
申请日：2012-11-21
申请人： The Board of Regents of the University of Texas S
发明人： Jung-Mo AHN , Ganesh RAJ
IPC分类号： A61K31/167 , A61N5/10 , A61K31/24 , A61K45/06 , C07C235/56 , C07C237/04
CPC分类号： C07C237/44 , A61B2017/00274 , A61F7/10 , A61K31/167 , A61K31/24 , A61K31/365 , A61K45/06 , A61N5/10 , C07C235/56 , C07C237/04 , A61K2300/00
摘要： The present invention includes bis- and tris-benzamide compounds that block AR signaling and have activity against prostate cancer. Uses for these compounds, and pharmaceutical compositions containing the same, also are provided.
摘要翻译：本发明包括阻断AR信号并具有抗前列腺癌活性的双 - 和三 - 苯甲酰胺化合物。也提供了这些化合物的用途和含有它们的药物组合物。

97. 发明申请

US20130150410A1 Controlled Release Ion Channel Modulator Compositions and Methods for the Treatment of Otic Disorders 审中-公开
标题翻译：控制释放离子通道调节剂组合物和治疗眼病的方法
公开(公告)号：US20130150410A1
公开(公告)日：2013-06-13
申请号：US13762241
申请日：2013-02-07
申请人： OTONOMY, INC. , THE REGENTS OF THE UNIVERSITY OF CALIF
发明人： Jay Lichter , Andrew M. Trammel , Fabrice Piu , Qiang Ye , Michael Christopher Scaife , Benedikt Vollrath , Sergio G. Durón , Luis A. Dellamary , Carl Lebel , Jeffrey P. Harris
IPC分类号： A61K9/00 , A61K31/24 , A61K31/444 , A61K31/27 , A61K31/44
CPC分类号： A61K9/0046 , A61K9/0019 , A61K9/06 , A61K9/122 , A61K9/127 , A61K9/1647 , A61K9/5153 , A61K9/7007 , A61K31/24 , A61K31/27 , A61K31/44 , A61K31/444 , A61K47/34 , A61K47/36 , A61K47/38 , A61K47/40
摘要： Disclosed herein are compositions and methods for the treatment of otic disorders with ion channel modulators. In these methods, the ion channel modulator compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of the ion channel modulator compositions and formulations onto the auris interna target areas, or via perfusion into the auris interna structures.
摘要翻译：本文公开了用离子通道调节剂治疗耳部疾病的组合物和方法。在这些方法中，离子通道调节剂组合物和制剂通过将离子通道调节剂组合物和制剂直接施用到内耳目标区域上，或通过灌注到内耳结构中而局部施用于患有耳科疾病的个体。

98. 发明申请

US20130136797A1 Modified Release Formulations Containing Drug-Ion Exchange Resin Complexes 有权
标题翻译：含有药物 - 离子交换树脂配合物的改性释放制剂
公开(公告)号：US20130136797A1
公开(公告)日：2013-05-30
申请号：US13746654
申请日：2013-01-22
申请人： TRIS PHARMA, INC.
发明人： Ketan Mehta , Yu-Hsing Tu
IPC分类号： A61K9/50
CPC分类号： A61K47/585 , A61K9/0053 , A61K9/0056 , A61K9/0095 , A61K9/10 , A61K9/14 , A61K9/1635 , A61K9/1664 , A61K9/167 , A61K9/2013 , A61K9/2027 , A61K9/2031 , A61K9/2077 , A61K9/2081 , A61K9/4866 , A61K9/5021 , A61K9/5026 , A61K31/135 , A61K31/137 , A61K31/155 , A61K31/192 , A61K31/216 , A61K31/24 , A61K31/4402 , A61K31/4458 , A61K31/485 , A61K45/06 , A61K47/14 , A61K47/32 , A61K47/6921 , A61K47/6927 , A61K47/6933
摘要： An aqueous liquid suspension containing a coated drug-ion exchange resin complex comprising a core composed of an amphetamine complexed with a pharmaceutically acceptable ion-exchange resin and an uncoated amphetamine-ion exchange resin complex is provided. The coated amphetamine-ion exchange resin complex is in admixture with a polymer to form a matrix. The coating is a polyvinyl acetate polymer and a plasticizer. Methods of making the coated complex and the liquid suspension are described.
摘要翻译：提供了一种含有包被药物 - 离子交换树脂复合物的水性液体悬浮液，其包含由与药学上可接受的离子交换树脂络合的苯丙胺和未涂覆的苯丙胺 - 离子交换树脂复合物组成的核心。涂布的苯丙胺 - 离子交换树脂复合物与聚合物混合以形成基质。涂料是聚乙酸乙烯酯聚合物和增塑剂。描述制备涂覆的复合物和液体悬浮液的方法。

99. 发明申请

US20130102641A1 PRODRUGS OF GABA ANALOGS, COMPOSITIONS AND USES THEREOF 审中-公开
公开(公告)号：US20130102641A1
公开(公告)日：2013-04-25
申请号：US13714224
申请日：2012-12-13
申请人： XENOPORT, INC.
发明人： Mark A. Gallop , Kenneth C. Cundy , Cindy X. Zhou , Fenmei Yao , Jia-Ning Xiang , Ian R. Ollman , Fayang G. Qiu
IPC分类号： C07C271/22
CPC分类号： C07C229/28 , A61K31/22 , A61K31/24 , C07C271/22 , C07C309/29 , C07C2601/04 , C07C2601/14 , C07C2601/18
摘要： The present invention provides prodrugs of GABA analogs, pharmaceutical compositions of prodrugs of GABA analogs and methods for making prodrugs of GABA analogs. The present invention also provides methods for using prodrugs of GABA analogs and methods for using pharmaceutical compositions of prodrugs of GABA analogs for treating or preventing common diseases and/or disorders.

100. 发明授权

US08426463B2 [((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexanecarbonyl)-amino]-acetic acid isopropyl ester and related compounds and their use in therapy 有权
标题翻译： [（（1R，2S，5R）-2-异丙基-5-甲基 - 环己烷羰基） - 氨基] - 乙酸异丙酯和相关化合物及其在治疗中的用途
公开(公告)号：US08426463B2
公开(公告)日：2013-04-23
申请号：US13065971
申请日：2011-04-04
申请人： Edward T. Wei
发明人： Edward T. Wei
IPC分类号： A61K31/223 , A61K31/196 , A61K9/20 , A61K9/68 , A61P11/02 , A61P11/04
CPC分类号： A61K9/0056 , A61K9/0048 , A61K9/2018 , A61K31/24
摘要： The present invention pertains generally to the field of coolants and medical therapy. More particularly, the present invention relates to certain anti-nociceptive agents, such as [((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexanecarbonyl)-amino]-acetic acid isopropyl ester, that are potent and long-acting and selectively cooling for non-keratinized epithelial tissues as compared to keratinized epithelial tissues, and are useful, for example, for the treatment of (e.g., the alleviation of symptoms of; the amelioration of) sensory discomfort of non-keratinized stratified epithelial (NKSE) tissue; and so for treatment of: sensory discomfort of an ocular surface, an eyelid, a margin of an eyelid, an anterior part of an eyeball, a conjunctiva, a lachrymal system, a pre-corneal film, or a cornea, a lining of the oral cavity, an internal portion of the lips, a pharyngeal surface, an esophageal surface, or an anogenital surface; eye discomfort, e.g., caused by extended wear of contact lenses, by eye strain and/or fatigue, by air pollutants, by excessive exposure to the sun, by conjunctivitis, by dry eye syndrome; sensory discomfort associated with oral mucositis; airway (e.g., larynx, trachea, and/or bronchi) tightness, discomfort in the airways (e.g., larynx, trachea, and/or bronchi), choking, cough, and/or dyspnea, e.g., associated with asthma and/or chronic obstructive pulmonary diseases (COPD).
摘要翻译：本发明一般涉及冷却剂和药物治疗领域。更具体地，本发明涉及某些抗伤害感受剂，例如[（（1R，2S，5R）-2-异丙基-5-甲基 - 环己烷羰基） - 氨基] - 乙酸异丙酯，其是有效的和长的与角质化的上皮组织相比，对非角质化上皮组织的作用和选择性冷却，并且可用于例如非角质化分层上皮的治疗（例如，减轻症状，改善）感觉不适（NKSE）组织; 因此用于治疗：眼表面，眼睑，眼睑边缘，眼球前部，结膜，泪液系统，角膜前角膜或角膜的感觉不适，口腔，嘴唇的内部，咽表面，食管表面或肛门表面; 由眼睛疲劳和/或疲劳，空气污染物，过度暴露于阳光，结膜炎，干眼综合征引起的眼睛不适; 与口腔粘膜炎相关的感觉不适; 呼吸道（例如喉，气管和/或支气管）紧张，气道不适（例如喉，气管和/或支气管），窒息，咳嗽和/或呼吸困难，例如与哮喘和/或慢性相关阻塞性肺疾病（COPD）。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式