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91. 发明授权

US5913826A Wideband external pulse cardiac monitor 失效
标题翻译：宽带外部脉冲心脏监护仪
公开(公告)号：US5913826A
公开(公告)日：1999-06-22
申请号：US661910
申请日：1996-06-12
申请人： Seymour Blank
发明人： Seymour Blank
IPC分类号： A61B5/0225 , A61B7/04 , A61B5/00
CPC分类号： A61B5/02007 , A61B5/02208 , A61B5/0225 , A61B5/412 , A61B7/045 , A61B5/029 , A61B5/7239 , A61B5/726
摘要： An apparatus for assessing cardiovascular status of a mammal comprising a system for locally applying a pressure to an artery, capable of restricting blood flow through said artery, a wideband external pulse transducer, having an output, situated to measure acoustic signals proximate to said artery, and a computing device receiving said output for calculating, based on said output, a peripheral vascular impedance value. The systolic and diastolic pressure are determined by an appearance and disappearance of a high frequency signal upon changes in cuff pressure partially occluding arterial blood flow. The arterial pressure waveform is estimated by measuring the wideband acoustic emissions from a non-occluded artery. The peak and trough of the arterial pressure waveform are calibrated with the determined systolic and diastolic pressures. The systemic vascular resistance is computed by occluding blood flow with a supersystolic pressure, and calculating, based on a natural logarithm of a difference in amplitude between a first major systolic peak and first major systolic trough and an amplitude of a second major systolic peak, a first order linear equation, which may be normalized for body surface area. The data obtained may also be used to analyze cardiac output, arterial compliance and dp/dt.
摘要翻译：一种用于评估哺乳动物的心血管状态的装置，包括用于局部施加压力的系统，所述系统能够限制通过所述动脉的血液流动，具有输出的宽带外部脉冲换能器，所述输出位于用于测量靠近所述动脉的声学信号，以及接收所述输出的计算装置，用于基于所述输出计算周围血管阻抗值。收缩压和舒张压由袖带压力部分阻塞动脉血流量变化时高频信号的出现和消失确定。通过测量来自非闭塞动脉的宽带声发射来估计动脉压波形。用确定的收缩压和舒张压校准动脉压波形的峰值和谷值。通过闭塞具有超收缩压的血流来计算全身血管阻力，并且基于第一主要收缩期峰和第一主收缩期波峰与第二主要收缩期峰值之间的振幅差的自然对数来计算，一阶线性方程，其可以被归一化为体表面积。所获得的数据也可用于分析心输出量，动脉顺应性和dp / dt。

92. 发明授权

US5853371A System and method for evaluating the degree of arterial elasticity in a living subject 失效
标题翻译：用于评估活体受试者动脉弹性程度的系统和方法
公开(公告)号：US5853371A
公开(公告)日：1998-12-29
申请号：US867978
申请日：1997-06-03
申请人： Hidekatsu Inukai , Hiroshi Sakai, deceased
发明人： Hidekatsu Inukai , Hiroshi Sakai, deceased
IPC分类号： A61B5/02 , A61B5/0205 , A61B5/0225 , A61B5/0245 , A61B5/0285 , A61B5/021 , A61B5/022
CPC分类号： A61B5/0225 , A61B5/0285
摘要： A system and method for evaluating the degree of elasticity of a subject's arteries includes an inflatable cuff that is wrapped around a portion of the living subject. A cuff pressure regulating circuit changes the constriction pressure applied by the inflatable cuff to the subject. A time-difference determining circuit determines a time difference between predetermined periodic points on an electrocardiographic waveform of the living subject and predetermined periodic points on corresponding pressure pulse waves of the living subject. An arterial elasticity evaluation circuit determines the degree of elasticity of the subject's arteries based on the relationship between changes in the time difference determined by the time-difference determining circuit and changes in the constriction pressure applied by the inflatable cuff.
摘要翻译：用于评估受试者的动脉的弹性程度的系统和方法包括缠绕在活体的一部分上的可充气袖带。袖带压力调节电路将由充气袖带施加的收缩压力改变到被摄体。时差确定电路确定活体的心电图波形上的预定周期点与生物体对应的压力脉搏波上的预定周期点之间的时间差。动脉弹性评价电路基于由时差判断电路确定的时间差的变化与由充气袖带施加的收缩压的变化之间的关系来确定被检体的动脉的弹性程度。

93. 发明授权

US5772601A Apparatus for evaluating cardiac function of living subject 失效
标题翻译：用于评估活体受试者心脏功能的装置
公开(公告)号：US5772601A
公开(公告)日：1998-06-30
申请号：US703360
申请日：1996-08-26
申请人： Tohru Oka , Hideichi Tsuda
发明人： Tohru Oka , Hideichi Tsuda
IPC分类号： A61B5/021 , A61B5/022 , A61B5/0225 , A61B5/0285 , A61B5/029 , A61B5/29
CPC分类号： A61B5/02225 , A61B5/02028 , A61B5/021 , A61B5/02116 , A61B5/02125 , A61B5/02208 , A61B5/0225 , A61B5/0285 , A61B5/029
摘要： An apparatus for evaluating a blood-ejecting function of a heart of a living subject, including a pressure pulse wave sensor which is adapted to be worn on a body portion of the subject to detect a pressure pulse wave which is produced from an artery of the subject in synchronism with a heartbeat of the subject, a first determining device for determining a first value of an index corresponding to a systolic area which is defined by a waveform of a first heartbeat-synchronous pulse of the pressure pulse wave detected by the pressure pulse wave sensor before the subject undergoes a physical exercise, a second determining device for determining a second value of the index corresponding to a systolic area which is defined by a waveform of a second heartbeat-synchronous pulse of the pressure pulse wave detected by the pressure pulse wave sensor after the subject undergoes the physical exercise, and an evaluating device for evaluating the blood-ejecting function of the heart of the subject, based on the determined first and second values of the index.
摘要翻译：一种用于评估活体的心脏的血液喷射功能的装置，包括：压力脉搏波传感器，其适于佩戴在所述对象的身体部分上，以检测从所述受试者的动脉产生的压力脉搏波; 受试者与受试者的心跳同步，第一确定装置，用于确定与由压力脉冲检测的压力脉搏波的第一心跳同步脉冲的波形所定义的收缩期面积对应的第一值波形传感器，在对象进行体育锻炼之前，第二确定装置，用于确定与由压力脉冲检测到的压力脉搏波的第二心跳同步脉冲的波形所定义的收缩期面积对应的第二值被检体进行体育锻炼后的波传感器，以及评价被检体的心脏的排血功能的评价装置，基于所确定的索引的第一和第二值。

94. 发明授权

US5579776A Oscillometric blood pressure monitor with enhanced cuff pressure control 失效
标题翻译：示波器血压监测器，增强袖带压力控制
公开(公告)号：US5579776A
公开(公告)日：1996-12-03
申请号：US372137
申请日：1995-01-13
申请人： Richard Medero
发明人： Richard Medero
IPC分类号： A61B5/0225 , A61B5/00
CPC分类号： A61B5/02225 , A61B5/0225
摘要： An automated sphygmomanometer in which the so-called "air effect" (a slow rise or fall in cuff pressure caused by step inflates or deflates) is substantially eliminated by deflating (inflating) the pressure cuff to a pressure lower (higher) than the target pressure, waiting a short time interval, and then inflating (deflating) the pressure cuff to the target pressure. The driving force that causes the air effect to settle out after a step inflate or deflate is proportional to the size of the step change in pressure and is thus greatest during the wait time before the pressure cuff is inflated or deflated to the target pressure. Once at the target pressure, the remaining air effect is counteracted by the incremental air effect introduced by the latter inflate or deflate so that the air effect cancels out. The techniques of the invention provide most improved results for large inflates and deflates of 20 mm Hg or more or first deflates after a complete inflate of the pressure cuff where the air effects are most pronounced.
摘要翻译：通过将压力袖带放气（膨胀）至低于（高于目标值）的压力，基本上消除了所谓的“空气效应”（由步骤膨胀或放气引起的袖带压力的缓慢上升或下降）的自动血压计压力，等待短时间间隔，然后使压力袖带膨胀（放气）至目标压力。导致空气效应在充气或放气的步骤之后沉降的驱动力与压力阶跃变化的大小成比例，并且因此在压力气囊膨胀或放气到目标压力之前的等待时间内是最大的。一旦达到目标压力，剩余的空气效应就由后者膨胀或放气引起的增量空气效应抵消，从而消除空气效应。本发明的技术为空气效应最显着的压力袖带的完全膨胀之后提供了大的充气和20mm Hg或更多的放气的最大改进的结果或首先放气。

95. 发明授权

US5564426A Blood pressure measuring system 失效
标题翻译：血压测量系统
公开(公告)号：US5564426A
公开(公告)日：1996-10-15
申请号：US211720
申请日：1994-04-25
申请人： Nobuo Iwai
发明人： Nobuo Iwai
IPC分类号： A61B5/022 , A61B5/0225
CPC分类号： A61B5/02225 , A61B5/022 , A61B5/0225
摘要： By a pressure data separating device 24, a net cuff pressure and an arterial pulse component are separately extracted from a cuff pressure of an occluding cuff which is an electrical signal provided from an A/D converter 23. A waveform value indicative of a waveform of each arterial pulse is computed by an arterial pulse deriving section 24a. An arithmetic operation device 26 is capable of detecting a characteristic value from a time series of the waveform values and determining systolic and diastolic blood pressures of a subject in accordance with a net cuff pressure corresponding to the characteristic value. In the present invention, since particular times associated with the systolic and diastolic blood pressures are derived by an analysis of the waveform of each arterial pulse, the blood pressures can be accurately determined while preventing an error in measurement caused by individual difference of the subject.
摘要翻译： PCT No.PCT / JP93 / 01176 Sec。 371日期1994年04月25日 102（e）1994年4月25日PCT PCT 1993年8月23日PCT公布。出版物WO94 / 04074 日期1994年3月3日通过压力数据分离装置24，从作为从A / D转换器23提供的电信号的闭塞袖带的袖带压力单独提取净袖带压力和动脉脉冲成分。波形值通过动脉脉冲导出部分24a来计算指示每个动脉脉搏的波形。算术运算装置26能够根据波形值的时间序列检测特征值，并根据对应于特征值的净袖带压力确定被检体的收缩压和舒张压。在本发明中，由于通过分析每个动脉脉搏的波形来导出与收缩压和舒张压相关的特定时间，因此能够精确地确定血压，同时防止由个体差异导致的测量误差。

96. 发明授权

US5404878A Method and apparatus for automatic non-invasive monitoring of a patient's blood pressure 失效
标题翻译：自动无创监测患者血压的方法和装置
公开(公告)号：US5404878A
公开(公告)日：1995-04-11
申请号：US208444
申请日：1994-03-09
申请人： Michael Frankenreiter , Gerhard Goebl
发明人： Michael Frankenreiter , Gerhard Goebl
IPC分类号： A61B5/0225 , A61B5/00
CPC分类号： A61B5/02225 , A61B5/0225 , A61B5/7207
摘要： In a method for automatic non-invasive monitoring of a patient's blood pressure, a cuff is applied around an arm of the patient and inflated to a predetermined pressure. Thereafter the pressure applied to said cuff is stepwise reduced. On the basis of the amplitudes or peak-to-peak values of the oscillations of the pressure signal measured at the individual pressure steps, a blood pressure value is derived. In order to be able to take arrhythmias into consideration in such a measurement method, oscillations that have been recognized to be artifact-free are sorted in accordance with various criteria, whereupon the frequency is determined with which the oscillations fulfill these criteria. Depending on the frequency with which the criteria are fulfilled, specific oscillations are selected whose mean value is utilized for determining the blood pressure.
摘要翻译：在用于自动无创监测患者血压的方法中，将袖带施加在患者的手臂周围并充气至预定压力。此后施加到所述袖带的压力逐步减小。基于在各个压力步骤测量的压力信号的振荡的振幅或峰 - 峰值，导出血压值。为了能够在这种测量方法中考虑心律失常，根据各种标准对已经被认为是无伪影的振荡进行排序，由此确定振荡满足这些标准的频率。根据满足标准的频率，选择特定的振荡，其平均值用于确定血压。

97. 发明授权

US5316006A Electronic blood pressure meter 失效
标题翻译：电子血压计
公开(公告)号：US5316006A
公开(公告)日：1994-05-31
申请号：US27537
申请日：1993-03-08
申请人： Katuyuki Inage , Yumi Saito , Zhang Zhimming , Toru Fujii , Osamu Shirasaki
发明人： Katuyuki Inage , Yumi Saito , Zhang Zhimming , Toru Fujii , Osamu Shirasaki
IPC分类号： A61B5/022 , A61B5/0225 , A61B7/04
CPC分类号： A61B7/045 , A61B5/0225
摘要： An electronic blood pressure meter including a cuff, a pressurizing means for inflating the cuff, a pressure sensing device for sensing a fluid pressure within the cuff, a pulse wave detecting device for detecting a pulse wave component included in the cuff, a systolic pressure estimating device for estimating a systolic pressure value based on the pulse wave and the cuff pressure detected in a pressurizing process, a pressurization volume computing device for computing a pressurization volume based on the estimated the systolic pressure value, a pressure decreasing device for decreasing the cuff pressure after reaching the pressurization volume, a blood vessel information detecting device for detecting blood vessel information such as pulse wave components in the pressure decreasing process, a blood pressure value determining device for determining systolic and diastolic pressure values based on the blood vessel information and the cuff pressure, a pulse wave component dispersion degree detecting device for detecting a dispersion degree of the pulse wave components obtained in the pressure decreasing process, and a pressurization volume controlling device for controlling the pressurization volume by the pressurizing device.
摘要翻译：一种电子血压计，包括袖带，用于使袖带充气的加压装置，用于感测袖带内的流体压力的压力检测装置，用于检测包括在袖带中的脉搏波分量的脉搏波检测装置，收缩压估计用于基于在加压过程中检测到的脉搏波和袖带压来估计收缩压值的装置，用于基于估计的收缩压值计算加压体积的加压容量计算装置，用于降低袖带压力的压力降低装置在达到加压容积之后，用于检测血压信息的血管信息检测装置，例如压力降低过程中的脉波成分，血压值确定装置，用于根据血管信息和袖带确定收缩压和舒张压值压力，脉波分量分散度 ee检测装置，用于检测在减压过程中获得的脉波成分的分散度;以及加压量控制装置，用于通过加压装置控制加压量。

98. 发明授权

US5280790A Automatic blood pressure monitor having reduced data loss sensitivity to cuff pressure changes 失效
标题翻译：自动血压计具有降低对袖带压力变化的数据丢失敏感性
公开(公告)号：US5280790A
公开(公告)日：1994-01-25
申请号：US8731
申请日：1993-01-25
申请人： James R. Brooks
发明人： James R. Brooks
IPC分类号： A61B5/0225 , A61B5/00
CPC分类号： A61B5/02225 , A61B5/0225
摘要： An automatic blood pressure monitor having a blood pressure cuff, an air pump applying pressurized air to the cuff, an air valve selectively venting the cuff, and a pressure transducer generating an output signal having a D.C. component indicative of the steady-state pressure in the cuff, and an A.C. component indicative of oscillometric pulses. The pressure transducer output is amplified and applied to an analog-to-digital converter which generates a digital word indicative of the steady-state cuff pressure. The amplified pressure transducer output is also applied to one input of a differential amplifier having an output that is applied to an analog-to-digital converter having a limited operating range. The other input of the amplifier receives an offset signal from a voltage source to offset the amplified pressure transducer output so that the output of the differential amplifier will not exceed the operating range of the analog-to-digital converter.
摘要翻译：一种具有血压袖带的自动血压监测器，向袖带施加加压空气的空气泵，选择性排气袖带的空气阀，以及产生具有指示稳态压力的DC分量的输出信号的压力传感器袖带和表示示波器脉冲的AC分量。压力传感器输出被放大并施加到模数转换器，其产生指示稳态袖带压力的数字字。放大的压力传感器输出也被施加到具有施加到具有有限工作范围的模数转换器的输出的差分放大器的一个输入。放大器的另一个输入接收来自电压源的偏移信号以偏移放大的压力传感器输出，使得差分放大器的输出不会超过模数转换器的工作范围。

99. 发明授权

US5277187A Apparatus and method for improving the performance of an automatic blood pressure cuff 失效
标题翻译：提高自动血压袖带性能的装置和方法
公开(公告)号：US5277187A
公开(公告)日：1994-01-11
申请号：US774990
申请日：1991-10-15
申请人： Terrance L. Pillsbury
发明人： Terrance L. Pillsbury
IPC分类号： A61B5/022 , A61B5/0225 , A61B5/02
CPC分类号： A61B5/02141 , A61B5/02233 , A61B5/0225
摘要： An improved blood pressure measuring device includes a filter intermediate the pressure cuff and the bleed valve to prevent dust, dirt, and other debris from clogging the bleed valve and causing significant damage to the blood pressure measuring device. Further, a data processor assembly is operated in accordance with a method designed to compensate the blood pressure measurement for any resistance added to the pneumatic system as a result of the air filter. The data processor assembly further determines when the filter is clogged thereby indicating that the measurement can no longer be accepted as accurate and the device may be dangerous to the patient.
摘要翻译：改进的血压测量装置包括在压力袖带和放气阀之间的过滤器，以防止灰尘，污垢和其它碎屑堵塞放气阀并对血压测量装置造成显着的损害。此外，数据处理器组件根据设计用于补偿由于空气过滤器而对气动系统添加的任何电阻的血压测量的方法进行操作。数据处理器组件进一步确定过滤器何时堵塞，从而指示测量值不能再被接受为准确的，并且该装置对患者可能是危险的。

100. 发明授权

US5255686A Continuous noninvasive blood pressure measuring apparatus and method 失效
标题翻译：连续无创血压测量仪及方法
公开(公告)号：US5255686A
公开(公告)日：1993-10-26
申请号：US907795
申请日：1992-07-02
申请人： Sunao Takeda , Hideo Ozawa , Mitsushi Hyogo , Yoshinobu Nakae
发明人： Sunao Takeda , Hideo Ozawa , Mitsushi Hyogo , Yoshinobu Nakae
IPC分类号： A61B5/022 , A61B5/0225 , A61B5/00
CPC分类号： A61B5/0225
摘要： In a continuous noninvasive blood pressure measuring apparatus, a systolic pressure, diastolic pressure, and mean arterial pressure for calibration are measured according to the output of a pressure sensor, a cuff pressure is set lower than the diastolic pressure by a cuff pressure control section, and a reference pulse wave is obtained from the arithmetic means of a plurality of cuff pulse waves. A CPU calculates the peak value and the bottom value of the reference pulse wave, and a cuff pressure mean value corresponding to the D.C. component of the reference pulse wave, and further calculates coefficients which are used to allow the peak value, bottom value and cuff pressure mean value thus obtained to correspond to correspond to the systolic pressure, diastolic pressure, and mean arterial pressure, respectively. The CPU calculates according to the output of a temperature sensor a cuff pressure temperature compensation value for compensating for an amount of variation of the cuff pressure which varies with the temperature of the cuff. In addition, the CPU, while compensating the cuff pressure, which is read continuously, with the cuff pressure temperature compensation value, continuously calculates a blood pressure by utilizing the cuff pressure thus compensated, and the coefficients provided by the coefficient calculating section, and the cuff pulse waves read continuously.
摘要翻译：在连续无创血压测定装置中，根据压力传感器的输出来测量收缩压，舒张压和用于校准的平均动脉压，通过袖带压力控制部将袖带压设定为低于舒张压，并且从多个袖带脉冲波的运算装置获得参考脉搏波。 CPU计算参考脉搏波的峰值和底值，以及与参考脉搏波的直流分量对应的袖带压力平均值，并进一步计算用于允许峰值，底值和袖带由此获得的压力平均值分别对应于收缩压，舒张压和平均动脉压。 CPU根据温度传感器的输出计算袖带压力温度补偿值，用于补偿袖带压力的变化量随袖带的温度而变化。此外，CPU在通过袖带压力温度补偿值连续读取补偿袖带压力的同时，通过利用这样补偿的袖带压力连续计算血压，并且由系数计算部提供的系数和袖带脉搏波连续读取。

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