专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

91. 发明授权

US07442696B2 Mineralocorticoid receptor modulator compounds, processes for their preparation, and their uses 失效
标题翻译：盐皮质激素受体调节剂化合物，其制备方法及其用途
公开(公告)号：US07442696B2
公开(公告)日：2008-10-28
申请号：US11622983
申请日：2007-01-12
申请人： Robert I. Higuchi , Lin Zhi , Mark E. Adams , Yan Liu , Donald S. Karanewsky
发明人： Robert I. Higuchi , Lin Zhi , Mark E. Adams , Yan Liu , Donald S. Karanewsky
IPC分类号： C07D265/12 , A61K31/535
CPC分类号： C07D265/18 , C07D413/04
摘要： This invention relates to compounds that bind to mineralocorticoid receptors and/or modulate activity of mineralocorticoid receptors, and to methods for making and using such compounds. Some embodiments relate to compounds of Formula I: or a pharmaceutically acceptable salt, ester, amide, or prodrug thereof, wherein R1 —R10 are as defined herein.
摘要翻译：本发明涉及结合盐皮质激素受体的化合物和/或调节盐皮质激素受体的活性，以及制备和使用这些化合物的方法。一些实施方案涉及式I化合物或其药学上可接受的盐，酯，酰胺或前药，其中R 1至R 10如本文所定义。

92. 发明申请

US20080223121A1 APTAMER PROBE FOR LOCATING MOLECULES AND METHOD OF USE 审中-公开
标题翻译：用于定位分子的APTAMER探针和使用方法
公开(公告)号：US20080223121A1
公开(公告)日：2008-09-18
申请号：US11948960
申请日：2007-11-30
申请人： Liyun Lin , Hao Yan , Yan Liu , Stuart Lindsay
发明人： Liyun Lin , Hao Yan , Yan Liu , Stuart Lindsay
IPC分类号： G01B5/28
CPC分类号： G01Q60/42
摘要： An atomic force microscope and a method for detecting interactions between a probe and at least one sensed agent on a scanned surface is provided. The microscope has a scanning probe with a tip that is sensitive to a property of said scanned surface; a nucleic acid aptamer tethered to the tip of the probe; and a device for simultaneously recording the displacement of said probe tip as a function of time, topographic images, and the spatial location of interactions between said probe and the at least one sensed agent on said surface.
摘要翻译：提供了一种原子力显微镜和用于检测探针与被扫描表面上的至少一个检测到的试剂之间的相互作用的方法。显微镜具有扫描探针，其具有对所述扫描表面的特性敏感的尖端; 连接到探针末端的核酸适配子; 以及用于根据时间，地形图像以及所述探针和所述表面上的所述至少一个感测到的感测剂之间的相互作用的空间位置同时记录所述探针尖端的位移的装置。

93. 发明授权

US07391126B2 Systems and methods for an integrated electrical sub-system powered by wind energy 有权
标题翻译：由风能供电的综合电气子系统的系统和方法
公开(公告)号：US07391126B2
公开(公告)日：2008-06-24
申请号：US11427883
申请日：2006-06-30
申请人： Yan Liu , Luis Jose Garces
发明人： Yan Liu , Luis Jose Garces
IPC分类号： H02P9/00
CPC分类号： F03D9/257 , F03D7/00 , F03D9/11 , F03D9/19 , F03D9/255 , F03D9/28 , F05B2220/62 , F05B2260/80 , H02J3/386 , Y02A20/141 , Y02E10/723 , Y02E10/763
摘要： Various embodiments relate to systems and methods related to an integrated electrically-powered sub-system and wind power system including a wind power source, an electrically-powered sub-system coupled to and at least partially powered by the wind power source, the electrically-powered sub-system being coupled to the wind power source through power converters, and a supervisory controller coupled to the wind power source and the electrically-powered sub-system to monitor and manage the integrated electrically-powered sub-system and wind power system.
摘要翻译：各种实施例涉及与集成电动子系统和风力发电系统有关的系统和方法，所述系统和方法包括风力发电源，耦合到并且至少部分地由风力发电源供电的电动子系统，电力子系统通过电力转换器耦合到风力发电源，以及耦合到风力发电源和电动子系统的监控控制器，以监测和管理集成的电动子系统和风力发电系统。

94. 发明申请

US20080041706A1 Operating button device 失效
标题翻译：操作按钮装置
公开(公告)号：US20080041706A1
公开(公告)日：2008-02-21
申请号：US11803987
申请日：2007-05-16
申请人： Yan Liu
发明人： Yan Liu
IPC分类号： H01H3/04
CPC分类号： H01H13/705 , H01H23/30 , H01H2221/016 , H01H2221/036 , H01H2231/046
摘要： An operating button device of the present invention is adapted for use with an electronic apparatus, and includes first and second operating button sets and an elastic component. The first operating button set includes a mounting seat and a pair of press buttons disposed on the mounting seat. The second operating button set includes a toggle button rotatable relative to the mounting seat, and a pair of contact pieces disposed on a bottom part of the toggle button. The elastic component has a securing end disposed on the mounting seat, and a restoring end opposite to the securing end and in sleeving engagement with the toggle button.
摘要翻译：本发明的操作按钮装置适用于电子设备，并且包括第一和第二操作按钮组和弹性部件。第一操作按钮组包括安装座和设置在安装座上的一对按钮。第二操作按钮组包括可相对于安装座旋转的切换按钮，以及设置在切换按钮的底部的一对接触片。弹性部件具有设置在安装座上的固定端以及与固定端相对的恢复端，并且与拨动按钮套接合。

95. 发明申请

US20070115545A1 Method for automatically aligning telescope 有权
标题翻译：望远镜自动对准的方法
公开(公告)号：US20070115545A1
公开(公告)日：2007-05-24
申请号：US11285030
申请日：2005-11-23
申请人： Chin-Chuan Chen , Yan Liu
发明人： Chin-Chuan Chen , Yan Liu
IPC分类号： G02B23/00
CPC分类号： G02B23/16 , Y10S359/90
摘要： A manual controller commands a telescope mount to automatically track a specific bright star after the image of the star is located to center of an electronic eyepiece and a timer is started. The average moving speed of the bright star is calculated after a predetermined elapsed time to acquire the right ascension (RA) and the declination (DEC) coordinates of this bright star. Subsequently, the RA and DEC coordinates are compared with pre-stored data contained within a database used to identify the bright star. The celestial sphere coordinates of the telescope can be determined after a minimum of one bright star is identified. In the auto-tracking procedure, the manual controller controls movement of telescope by feedbacks of the drifting speed and direction of the specific bright star in an electronic eyepiece for the purpose of keeping the specific bright star in the center of the electronic eyepiece.
摘要翻译：手动控制器命令望远镜安装座，在星形图像位于电子目镜的中心并启动定时器之后自动跟踪特定的明亮星。在预定的经过时间之后计算亮星的平均移动速度，以获得该亮星的右上升（RA）和偏角（DEC）坐标。随后，将RA和DEC坐标与包含在用于识别亮星的数据库中的预存数据进行比较。望远镜的天球坐标可以在识别出最少的一颗明亮星之后确定。在自动跟踪过程中，手动控制器通过电子目镜中特定亮星的漂移速度和方向的反馈来控制望远镜的移动，目的是保持电子目镜中心的特定亮星。

96. 发明申请

US20060223829A1 Hydroxysteroid dehydrogenase inhibitors 失效
标题翻译：羟基类固醇脱氢酶抑制剂
公开(公告)号：US20060223829A1
公开(公告)日：2006-10-05
申请号：US11392297
申请日：2006-03-28
申请人： Kathleen Aertgeerts , Nancy Brennan , Sheldon Cao , Edcon Chang , Andre Kiryanov , Yan Liu
发明人： Kathleen Aertgeerts , Nancy Brennan , Sheldon Cao , Edcon Chang , Andre Kiryanov , Yan Liu
IPC分类号： A61K31/496 , A61K31/445 , C07D241/04
CPC分类号： C07D241/38 , C07D207/48 , C07D209/08 , C07D211/18 , C07D211/22 , C07D211/34 , C07D211/38 , C07D211/54 , C07D211/58 , C07D211/62 , C07D211/76 , C07D211/96 , C07D213/70 , C07D213/74 , C07D215/04 , C07D215/42 , C07D215/58 , C07D217/02 , C07D217/06 , C07D217/08 , C07D217/22 , C07D217/24 , C07D231/18 , C07D231/56 , C07D233/42 , C07D235/26 , C07D239/14 , C07D241/08 , C07D241/50 , C07D261/10 , C07D265/36 , C07D271/12 , C07D277/56 , C07D277/58 , C07D277/62 , C07D279/16 , C07D285/14 , C07D285/16 , C07D295/26 , C07D307/68 , C07D307/79 , C07D333/62 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D409/12 , C07D413/04 , C07D471/08 , C07D487/04 , C07D487/08 , C07D491/10 , C07D513/04
摘要： Compounds, pharmaceutical compositions, kits and methods are provided for use with hydroxysteroid dehydrogenases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
摘要翻译：提供化合物，药物组合物，试剂盒和方法用于含有选自以下的化合物的羟基类固醇脱氢酶：其中变量如本文所定义。

97. 发明申请

US20060186046A1 Ion chromatography system using catalytic gas elimination 有权
标题翻译：离子色谱系统采用催化气体消除
公开(公告)号：US20060186046A1
公开(公告)日：2006-08-24
申请号：US11065335
申请日：2005-02-23
申请人： Yan Liu , Christopher Pohl , Nebojsa Avdalovic , John Riviello , Archava Siriraks
发明人： Yan Liu , Christopher Pohl , Nebojsa Avdalovic , John Riviello , Archava Siriraks
IPC分类号： B01D15/08
CPC分类号： G01N30/96 , G01N30/62 , G01N2030/965
摘要： A liquid chromatographic system is provided including catalytically combining hydrogen and oxygen gases in the chromatography eluent stream in a catalytic gas elimination chamber, to form water and thereby reduce the gas content in the eluent stream. Also, a liquid ion chromatographic system in which the effluent from the detector is recycled to a membrane suppressor and then is mixed with a source of eluent for recycle to the chromatographic column.
摘要翻译：提供液相色谱系统，其包括在催化气体消除室中的色谱洗脱液流中催化结合氢气和氧气，形成水，从而降低洗脱液流中的气体含量。此外，液体离子色谱系统将来自检测器的流出物再循环至膜抑制剂，然后与洗脱液混合以再循环至色谱柱。

98. 发明申请

US20060134177A1 Amphiphilic block copolymers and their use 有权
标题翻译：两亲嵌段共聚物及其用途
公开(公告)号：US20060134177A1
公开(公告)日：2006-06-22
申请号：US11314930
申请日：2005-12-20
申请人： Yan Liu , Jons Hilborn , Hendrik Haitjema , Sverker Norrby , Thom Terwee
发明人： Yan Liu , Jons Hilborn , Hendrik Haitjema , Sverker Norrby , Thom Terwee
IPC分类号： A61F2/16 , A61K31/695
CPC分类号： A61K31/695 , A61L24/046 , A61L27/34 , Y10S623/926 , C08L83/04
摘要： The present invention relates to amphiphilic block copolymers comprising at least one block of hydrophilic units and at least one block of hydrophobic units, wherein at least one hydrophobic block contains siloxane units. The present invention may be particularly useful as a tissue adhesive or as a coating for an intraocular lens (IOL). As an IOL coating, copolymers according to the invention may be used, for example, to promote tissue adhesion for the prevention of posterior capsule opacification.
摘要翻译：本发明涉及包含至少一个亲水单元嵌段和至少一个疏水单元嵌段的两亲嵌段共聚物，其中至少一个疏水嵌段含有硅氧烷单元。本发明可以特别用作组织粘合剂或用作眼内透镜（IOL）的涂层。作为IOL涂层，根据本发明的共聚物可用于例如促进组织粘连以防止后囊混浊。

99. 发明申请

US20060134173A1 Polysiloxanes, method of synthesis and ophthalmic compositions 审中-公开
标题翻译：聚硅氧烷，合成方法和眼用组合物
公开(公告)号：US20060134173A1
公开(公告)日：2006-06-22
申请号：US11303889
申请日：2005-12-16
申请人： Yan Liu , Jons Hilborn , Hendrik Haitjema
发明人： Yan Liu , Jons Hilborn , Hendrik Haitjema
IPC分类号： A61F2/16 , A61K31/695 , C07F7/02
CPC分类号： A61K31/695 , C08G77/08 , C08G77/24
摘要： A linear polysiloxane copolymer has at least one terminal hydroxyalkyl group. The copolymer is preparable by a process comprising a combination of a base-catalysed polymerisation with an acid-catalysed redistribution, and is suitable for preparing ophthalmic compositions for forming an intraocular lens in situ.
摘要翻译：线性聚硅氧烷共聚物具有至少一个末端羟烷基。共聚物可通过包括碱催化的聚合与酸催化的再分布的组合的方法制备，并且适用于制备用于原位形成眼内透镜的眼用组合物。

100. 发明申请

US20060057733A1 Capillary ion chromatography 有权
公开(公告)号：US20060057733A1
公开(公告)日：2006-03-16
申请号：US10944442
申请日：2004-09-16
申请人： Yan Liu , Victor Manuel Berber Barreto , Christopher Pohl , Nebojsa Avdalovic
发明人： Yan Liu , Victor Manuel Berber Barreto , Christopher Pohl , Nebojsa Avdalovic
IPC分类号： G01N30/02
CPC分类号： B01D15/363 , B01D15/361 , B01D15/367 , G01N30/96 , G01N2030/965
摘要： An apparatus for capillary ion chromatography comprising a suppressor comprising flow-through ion exchange packing in a housing and capillary tubing formed of a permselective ion exchange membrane, and at least partially disposed in said ion exchange packing. Also, a recycle conduit for aqueous liquid from the detector to the packing. Further, the capillary tubing may have weakly acidic or weakly basic functional groups. Also, a method for using the apparatus.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式