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91. 发明授权

US4362736A Guanidinothiazole compounds, and medical compositions containing them 失效
标题翻译：胍基噻唑化合物和含有它们的医药组合物
公开(公告)号：US4362736A
公开(公告)日：1982-12-07
申请号：US127902
申请日：1980-03-06
申请人： Yasufumi Hirata , Isao Yanagisawa , Yoshio Ishii , Masaaki Takeda
发明人： Yasufumi Hirata , Isao Yanagisawa , Yoshio Ishii , Masaaki Takeda
IPC分类号： C07D277/38 , C07D277/46 , C07D277/48 , C07D277/20 , A61K31/425
CPC分类号： C07D277/48 , C07D277/46
摘要： Novel guanidinothiazole compounds of the general formula ##STR1## wherein R represents a hydrogen atom or a lower alkyl group, Y represents a sulfur atom or a methylene group, m and n each represents an integer of 1-3, A represents the group shown by ##STR2## (wherein R.sub.1 represents a hydrogen atom, a cyano group, a carbamoyl group, a ureido group, a hydroxyl group, a lower alkoxy group, a lower acyl group, an acylamino group, an arylsulfamoyl group, an aralkyl group or a carboxymethyl group, an arylsulfamoyl group, an aralkyl group or a carboxymethyl group, R.sub.2 represents a hydrogen atom, a lower alkyl group, a lower alkenyl group, a lower alkynyl group, a cyano group or a lower acyl group, and R.sub.3 represents a hydrogen atom, a lower alkyl group, a hydroxyl group or a sulfamoyl group), and the pharmacologically acceptable acid addition salts thereof; these compounds are useful as gastric acid secretion inhibitors.
摘要翻译：新颖的通式为“IMAGE”的胍基噻唑化合物，其中R表示氢原子或低级烷基，Y表示硫原子或亚甲基，m和n各自表示1-3的整数，A表示由（其中R 1表示氢原子，氰基，氨基甲酰基，脲基，羟基，低级烷氧基，低级酰基，酰氨基，芳基氨磺酰基，芳烷基或羧甲基，芳基氨磺酰基，芳烷基或羧甲基，R2表示氢原子，低级烷基，低级烯基，低级炔基，氰基或低级酰基，R3表示氢原子，低级烷基，羟基或氨磺酰基）及其药理学上可接受的酸加成盐; 这些化合物可用作胃酸分泌抑制剂。

92. 发明授权

US4249927A Method and apparatus for manufacturing glass products by controlling free flow of low viscosity molten glass 失效
标题翻译：通过控制低粘度熔融玻璃的自由流动来制造玻璃制品的方法和装置
公开(公告)号：US4249927A
公开(公告)日：1981-02-10
申请号：US62879
申请日：1979-08-01
申请人： Fukushichi Fukuzaki , Yoshio Ishii , Masaki Fukuzawa
发明人： Fukushichi Fukuzaki , Yoshio Ishii , Masaki Fukuzawa
IPC分类号： C03B7/08 , C03B7/12
CPC分类号： C03B7/08 , C03B7/12
摘要： According to the first method according to the present invention, there is provided a method for manufacturing glass products by casting low viscosity glass into a mould while controlling free flow of the glass by storing and holding the glass continuously fed out of a feeder outlet in a region under the lower surface of a control member provided below the feeder outlet after a cutting step, whereby the operation for setting a next mould to receive the glass in position is facilitated, the shape of the flowing glass after cutting is made stable and homogeneous gob can be produced. According to the second method of the invention, glass products are manufactured by casting the glass into a mould while controlling the free flow of the glass continuously fed out of the feeder outlet by storing and holding the glass not only in a region under the lower surface of the control member but also in a region above the upper surface of the control member by raising and lowering the control member whereby the glass flow is controlled over a wider range of glass flowing speed.The above described two methods of the present invention are applicable not only to production of a gob for an optical glass but effectively to processes for forming boards, bars etc. respectively having certain dimensions and configurations after cutting off low viscosity glass fed continuously out of a feeder.
摘要翻译：根据本发明的第一种方法，提供了一种通过将低粘度玻璃浇铸到模具中来制造玻璃制品的方法，同时通过将连续地从供料器出口送出的玻璃储存和保持在在切割步骤之后设置在供料器出口下方的控制构件的下表面下方的区域，由此便于将下一个模具设置以接收玻璃就位的操作，切割后的流动玻璃的形状被制成稳定且均匀的料滴可以生产。根据本发明的第二种方法，玻璃制品是通过将玻璃浇注到模具中而制造的，同时通过不仅在下表面下方的区域中储存和保持玻璃，而连续地从供料器出口输送的玻璃的自由流动的控制构件，而且在控制构件的上表面上方的区域中，通过升高和降低控制构件，从而在更宽的玻璃流动范围内控制玻璃流。上述本发明的两种方法不仅可用于生产光学玻璃料滴，而且可有效地用于在切断连续从进料器

93. 发明授权

US4026927A Novel prostaglandin derivatives 失效
标题翻译：新型前列腺素衍生物
公开(公告)号：US4026927A
公开(公告)日：1977-05-31
申请号：US508252
申请日：1974-09-23
申请人： Masuo Murakami , Noriyoshi Inukai , Hidenori Iwamoto , Toshinari Tamura , Isao Yanagisawa , Osamu Hasegawa , Yoshio Ishii , Hideya Matsuda , Tetsuya Shiozaki , Kenichi Tomioka
发明人： Masuo Murakami , Noriyoshi Inukai , Hidenori Iwamoto , Toshinari Tamura , Isao Yanagisawa , Osamu Hasegawa , Yoshio Ishii , Hideya Matsuda , Tetsuya Shiozaki , Kenichi Tomioka
IPC分类号： C07C405/00 , C07C177/00
CPC分类号： C07C405/00
摘要： Novel prostaglandin derivatives are provided having the formula: ##STR1## wherein A represents ##STR2## one of R.sub.3 and R.sub.4 represents a hydrogen atom and the other of them represents a lower alkyl group; one of R.sub.5 and R.sub.6 represents a hydrogen atom and the other of them represents a hydroxyl group; and one of R.sub.7 and R.sub.8 represents a hydrogen atom and the other of them represents a lower alkyl group.The compounds of this invention have excellent effects as prostaglandin E.sub.2 and prostaglandin F.sub.2.sub..alpha..
摘要翻译：提供了具有下式的新型前列腺素衍生物：其中A表示R 3中的一个，R 4表示氢原子，另一个表示低级烷基; R5和R6之一表示氢原子，另一个表示羟基; R 7和R 8中的一个表示氢原子，另一个表示低级烷基。

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