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91. 发明申请

US20050025189A1 Remote testing of high speed data and voice communication networks 有权
标题翻译：远程测试高速数据和语音通信网络
公开(公告)号：US20050025189A1
公开(公告)日：2005-02-03
申请号：US10479431
申请日：2002-05-31
申请人： Roger Smith
发明人： Roger Smith
IPC分类号： H04L12/24 , H04L12/26 , H04M3/30 , H04M3/32
CPC分类号： H04M3/323 , H04L41/0659 , H04L41/0806 , H04L41/0856 , H04L43/50 , H04M3/2209 , H04M3/306
摘要： Faults or degradation of performance of a voice/data communication network (2) are identified without the need to dispatch service personnel by selectively testing isolated sections of the communication network. For some of these tests, the communication network address of a customer's modem under test (106, 114, 60, 66) is retrieved from a database (88) for use in directing these tests to the customer's modem (106, 114, 60, 66) and for emulating the customer's modem (106, 114, 60, 66) during one or more of the tests.
摘要翻译：识别语音/数据通信网络（2）的故障或性能下降，而不需要通过选择性地测试通信网络的隔离部分来派遣服务人员。对于这些测试中的一些，从数据库（88）检索被测客户调制解调器（106,114,60,66）的通信网络地址，以用于将这些测试引导到客户的调制解调器（106,114,60,66） 66）和用于在一个或多个测试期间模拟客户的调制解调器（106,114,60,66）。

92. 发明授权

US06713059B2 Antibodies raised against immunogenic conjugates of gram-negative bacterial autoinducer molecules 失效
标题翻译：针对革兰氏阴性细菌自身诱导剂分子的免疫原性缀合物产生抗体
公开(公告)号：US06713059B2
公开(公告)日：2004-03-30
申请号：US10121207
申请日：2002-04-11
申请人： Andrew S. Kende , Barbara H. Iglewski , Roger Smith , Richard P. Phipps , James P. Pearson
发明人： Andrew S. Kende , Barbara H. Iglewski , Roger Smith , Richard P. Phipps , James P. Pearson
IPC分类号： A61K3940
CPC分类号： C07D207/273 , A61K39/385 , A61K2039/505 , A61K2039/6081 , C07D263/26 , C07D307/33 , C07D333/36 , C07K16/1203 , C07K16/1214 , G01N33/56911 , Y10S435/975 , Y10S436/80 , Y10S436/804 , Y10S530/806 , Y10S530/808
摘要： The present invention relates to an immunogenic conjugate comprising a carrier molecule coupled to an autoinducer of a Gram negative bacteria. The immunogenic conjugate, when combined with a pharmaceutically acceptable carrier, forms a suitable vaccine for mammals to prevent infection by the Gram negative bacteria. The immunogenic conjugate is also used to raise and subsequently isolate antibodies or binding portions thereof which are capable of recognizing and binding to the autoinducer. The antibodies or binding portions thereof are utilized in a method of treating infections, a method of inhibiting autoinducer activity, and in diagnostic assays which detect the presence of autoinducers or autoinducer antagonists in fluid or tissue samples.
摘要翻译：本发明涉及包含与革兰氏阴性细菌的自动诱导剂偶联的载体分子的免疫原性缀合物。当与药学上可接受的载体组合时，免疫原性缀合物形成用于哺乳动物的合适的疫苗，以防止革兰氏阴性菌感染。免疫原性缀合物也用于引发和随后分离能够识别和结合自动诱导剂的抗体或其结合部分。抗体或其结合部分用于治疗感染的方法，抑制自身诱导剂活性的方法，以及用于检测流体或组织样品中自身诱导剂或自身诱导剂拮抗剂的存在的诊断测定。

93. 发明授权

US06058405A SIMD computation of rank based filters for M.times.N grids 失效
标题翻译： MxN网格的基于秩的滤波器的SIMD计算
公开(公告)号：US06058405A
公开(公告)日：2000-05-02
申请号：US965686
申请日：1997-11-06
申请人： Priyadarshan Kolte , Roger Smith
发明人： Priyadarshan Kolte , Roger Smith
IPC分类号： G06T5/20 , G06F17/10
CPC分类号： G06T5/20 , Y10S707/99937
摘要： One way of filtering graphics images to remove pixel dropout and shot noise while preserving overall image quality is to use non-linear filters based on rank order of an M.times.N grid of pixel values surrounding a pixel to be filtered. This rank order filter method for M.times.N grids first sorts columns, then sorts rows, and finally sorts diagonals to obtain either just a median filter value, a rank-based filter value, or a complete sorted order of the M.times.N grid. All of the sort operations are control-flow-free allowing implementation on SIMD processors processing multiple overlapping M.times.N grids in parallel. Advantage is taken of columns and rows that are shared among the horizontally and vertically overlapping M.times.N grids in the digital image to reduce the total number of sort operations for the image.
摘要翻译：过滤图形图像以消除像素丢失和拍摄噪声同时保持整体图像质量的一种方法是使用基于要滤波的像素周围的像素值的M×N网格的秩顺序的非线性滤波器。 MxN网格的这种排序过滤器方法首先对列进行排序，然后对行进行排序，最后对对角线进行排序，以获得MxN网格的中值过滤器值，基于排序的过滤器值或完整排序顺序。所有的排序操作都是无流控制的，允许在SIMD处理器上实现并行处理多个重叠的MxN网格。优点在数字图像中的水平和垂直重叠的MxN网格之间共享的列和行，以减少图像的排序操作的总数。

94. 发明授权

US5799143A Multiple context software analysis 失效
公开(公告)号：US5799143A
公开(公告)日：1998-08-25
申请号：US703261
申请日：1996-08-26
申请人： Farooq Butt , Roger Smith , Katherine E. Stewart
发明人： Farooq Butt , Roger Smith , Katherine E. Stewart
IPC分类号： G06F11/36 , G06F11/00
CPC分类号： G06F11/3612 , G06F11/3636 , G06F11/3644
摘要： A method for multiple context analysis of software applications in a multiprocessing (22, 23), multithreaded computer environment utilizes instrumentation code inserted (54, 55) into the applications. For each execution (67) of the application (60), a context set is selected (62). Execution of the instrumented code (67) provides information for analysis in an instrumentation buffer (82) addressed by a reserved register (80) or buffer pointer. The operating system is responsible for providing in the reserved register (80) the address of the instrumentation buffer (82) appropriate for each instrumented context executed. When the application (60) is done with an instrumentation buffer (82), the buffer may be processed by filter software (68). The combination of using a reserved register (80) and allowing the operating system to keep track of relevant context switches allows applications to be instrumented (54, 55) for various context sets without the necessity of modifying (53) or recompiling (52) the application software (60).

95. 外观设计

USD297153S Physical exerciser 失效
公开(公告)号：USD297153S
公开(公告)日：1988-08-09
申请号：US806213
申请日：1985-11-25
申请人： Roger Smith
设计人： Roger Smith

96. 发明授权

US12031421B2 Modular solution mining system and methods 有权
公开(公告)号：US12031421B2
公开(公告)日：2024-07-09
申请号：US17687089
申请日：2022-03-04
申请人： Max Maxwell , Major Patterson , Roger Smith
发明人： Max Maxwell , Major Patterson , Roger Smith
IPC分类号： E21B43/28 , E21B43/14 , E21B43/30
CPC分类号： E21B43/281 , E21B43/14 , E21B43/305
摘要： A modular solution mining method may include the steps of: providing an injection wellbore, the injection wellbore including a horizontal injection portion, in which the horizontal injection portion includes a toe end and heel end; providing a production wellbore, in which the production wellbore includes a horizontal production portion that is proximate to the toe end; injecting a solvent into the horizontal injection portion; generating a turbulent solvent flow proximate to the toe end to generate a mineral solution and an initial cavern proximate to the horizontal production portion; and motivating the mineral solution from the initial cavern, into the horizontal production portion, and to a surface location. Optionally, the method may include the step of repositioning the turbulent solvent flow to be closer to heel ends to generate mineral solution and subsequent caverns further from horizontal production wellbore.

97. 发明授权

US10466288B2 Fiber optic pulsed polarimetry 有权
公开(公告)号：US10466288B2
公开(公告)日：2019-11-05
申请号：US15428892
申请日：2017-02-09
申请人： Roger Smith
发明人： Roger Smith
IPC分类号： G01R29/08 , G01R33/032
摘要： This disclosure is directed to fiber optic pulsed polarimeters based on either streak camera or photodiode detection using a backscatter tailored optical fiber and the polarization optical time domain reflectometry technique for conducting remote diagnostic measurements of inducing fields along the fiber. The backscatter tailored optical fiber comprises a single mode fiber with an array of fiber Bragg gratings written to produce a predetermined distribution of backscatter signal in intensity and spectral content in response to a pulse propagating along the array. The fiber optic pulsed polarimeter includes a directional coupler that diverts the backscatter from the backscatter-tailored optical fiber to a polarization detection system for determining the polarization state of the backscatter as the polarized light pulse transits the backscatter-tailored optical fiber.

98. 发明授权

US09268538B2 Metadata driven user interface system and method 有权
标题翻译：元数据驱动的用户界面系统和方法
公开(公告)号：US09268538B2
公开(公告)日：2016-02-23
申请号：US12062511
申请日：2008-04-04
申请人： Jacob Taylor , Majed Itani , Roger Smith
发明人： Jacob Taylor , Majed Itani , Roger Smith
IPC分类号： G06F9/44 , G06F13/00
CPC分类号： G06F8/38 , G06F8/30
摘要： A metadata driven user interface system and method are provided. In an exemplary embodiment, a software-based customer relationship management system and method may include the metadata driven user interface system.
摘要翻译：提供了元数据驱动的用户界面系统和方法。在示例性实施例中，基于软件的客户关系管理系统和方法可以包括元数据驱动的用户界面系统。

99. 发明授权

US08207172B2 Pyrimidinothienoindazoles useful for the treatment of hyperproliferative disorders 失效
标题翻译：嘧啶噻吩并吲唑可用于治疗过度增殖性疾病
公开(公告)号：US08207172B2
公开(公告)日：2012-06-26
申请号：US11662416
申请日：2005-08-19
申请人： Chengzhi Zhang , Jacques Dumas , Qingming Zhu , Roger Smith , Qingjie Liu , Sharad Verma , Jason Duquette , Qian Zhao , Dongping Fan , Georgiy Bondar , Philip Coish
发明人： Chengzhi Zhang , Jacques Dumas , Qingming Zhu , Roger Smith , Qingjie Liu , Sharad Verma , Jason Duquette , Qian Zhao , Dongping Fan , Georgiy Bondar , Philip Coish
IPC分类号： C07D471/04
CPC分类号： C07D495/04 , C07D495/14
摘要： The invention relates to novel heterocycles of formula (I) processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders.
摘要翻译：本发明涉及式（I）的新型杂环，其制备方法及其用于制备用于治疗或预防病症，特别是过度增殖性疾病的药物的用途。

100. 发明申请

US20090215780A1 Preparation and Use of Aryl Alkyl Acid Derivatives for the Treatment of Obesity 审中-公开
标题翻译：芳基烷基酸衍生物用于治疗肥胖症的制备和应用
公开(公告)号：US20090215780A1
公开(公告)日：2009-08-27
申请号：US11918836
申请日：2006-04-18
申请人： Roger Smith , Derek Lowe , Philip Coish , Ann-Marie Campbell , Gan Wang , Manoj Patel , Gerogiy Bondar
发明人： Roger Smith , Derek Lowe , Philip Coish , Ann-Marie Campbell , Gan Wang , Manoj Patel , Gerogiy Bondar
IPC分类号： A61K31/5375 , C07C229/40 , A61K31/192 , A61K31/4418 , C07D213/75 , C07D295/195 , A61P3/04
CPC分类号： C07D209/24 , C07C233/54 , C07C233/55 , C07C233/63 , C07C233/81 , C07C235/40 , C07C235/56 , C07C275/42 , C07C311/08 , C07C311/13 , C07C311/21 , C07C311/29 , C07C311/51 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2602/08 , C07D207/06 , C07D209/08 , C07D209/42 , C07D209/44 , C07D211/16 , C07D213/56 , C07D213/75 , C07D215/08 , C07D235/06 , C07D239/16 , C07D261/10 , C07D265/30 , C07D295/205 , C07D307/14 , C07D307/30 , C07D307/52 , C07D307/85 , C07D309/04 , C07D309/08 , C07D333/24 , C07D333/62 , C07D333/68 , C07D335/02 , C07D401/04 , C07D405/12
摘要： This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
摘要翻译：本发明涉及某些芳基烷基酸化合物，组合物和治疗或预防肥胖症和相关疾病的方法。

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