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91. 发明申请

US20100078323A1 COMPONENT SEPARATING DEVICE AND CHEMICAL ANALYSIS DEVICE USING THE SAME 有权
标题翻译：组分分离装置和使用该组分分析装置的化学分析装置
公开(公告)号：US20100078323A1
公开(公告)日：2010-04-01
申请号：US12444485
申请日：2007-11-15
申请人： Makoto Takahashi , Masaya Nakatani
发明人： Makoto Takahashi , Masaya Nakatani
IPC分类号： G01N35/08 , B01D21/28
CPC分类号： B01L3/502761 , B01D21/283 , B01D21/32 , B01D2221/10 , B01L2200/0652 , B01L2300/0816 , B01L2400/0439 , C12M47/02
摘要： A vibrator has a large strength of a standing wave even with a low driving voltage, thereby improving the accuracy of component separation. A device according to the present invention includes a substrate having a channel groove provided in an upper surface of the substrate, a seal provided above the substrate so as to cover an upper opening of the channel groove, a projection provided on an outer side wall opposite to the channel groove, and a vibrator causing the projection to warp and vibrate in a depth direction of the channel groove. The warping vibration of the projection is amplified due to effect of leverage, and generates a large stress on the outer wall of the channel groove having the projection provided thereon. Consequently, the strength of a standing wave in the channel groove increases even for a low driving voltage, thereby improving the accuracy of component separation.
摘要翻译：振动器即使具有低驱动电压也具有大的驻波强度，从而提高了元件分离的精度。根据本发明的装置包括：衬底，其具有设置在衬底的上表面中的沟槽;密封件，设置在衬底上方以覆盖通道槽的上开口;突出部，设置在相对的外侧壁上并且使振动器沿着沟槽的深度方向翘曲而振动。突起的翘曲振动由于杠杆作用而被放大，并且在其上设置有突起的通道槽的外壁上产生大的应力。因此，即使对于低驱动电压，通道槽中驻波的强度也增加，从而提高部件分离的精度。

92. 发明授权

US07608417B2 Cell electro-physiological sensor and method of manufacturing the same 有权
标题翻译：细胞电生理传感器及其制造方法
公开(公告)号：US07608417B2
公开(公告)日：2009-10-27
申请号：US11272892
申请日：2005-11-14
申请人： Masaya Nakatani , Hiroshi Ushio , Soichiro Hiraoka , Abdellah Menikh
发明人： Masaya Nakatani , Hiroshi Ushio , Soichiro Hiraoka , Abdellah Menikh
IPC分类号： C12Q1/02
CPC分类号： G01N33/48728
摘要： A cell electro-physiological sensor includes a sensor chip including a partition board having a first surface and a second surface opposite to the first surface, a member for forming a first region provided on the first surface of the partition board, and a member for forming a second region provided on the second surface of the partition board. The partition board has a through-hole provided therein, the through-hole having a first opening which opens to the first surface, a second opening which opens to the second surface, and a wall. The first region contacts the first opening of the through-hole. The first region is arranged to contain cell suspension. The atomic ratio of carbon at the first surface of the partition board is not greater than 15 atomic percent of the composition of the first surface. The cell electro-physiological sensor causes the cell to be tightly held at the first opening of the through-hole in the partition board, thereby measuring a potential of the cell efficiently.
摘要翻译：细胞电生理传感器包括传感器芯片，其包括具有第一表面和与第一表面相对的第二表面的隔板，用于形成设置在隔板的第一表面上的第一区域的构件和用于形成设置在隔板的第二表面上的第二区域。分隔板具有设置在其中的通孔，该通孔具有通向第一表面的第一开口，通向第二表面的第二开口和壁。第一区域接触通孔的第一开口。第一个区域被设置成包含细胞悬浮液。分隔板的第一表面处的碳的原子比不大于第一表面的组成的15原子％。细胞电生理传感器使细胞紧密地保持在隔板的通孔的第一开口处，从而有效地测量细胞的电位。

93. 发明授权

US07384782B2 Polymerase chain reaction container and process for producing the same 有权
标题翻译：聚合酶链反应容器及其制备方法
公开(公告)号：US07384782B2
公开(公告)日：2008-06-10
申请号：US10485342
申请日：2003-07-03
申请人： Masaya Nakatani , Tetsuo Yukimasa
发明人： Masaya Nakatani , Tetsuo Yukimasa
IPC分类号： C12M1/00
CPC分类号： C07H21/00 , B01L3/502707 , B01L7/52 , B01L2300/0816 , B01L2300/0877 , B01L2300/0887 , B01L2300/185
摘要： The present invention provides a kit employed for polymerase chain reaction. The kit has a cavity and a flow channel on a substrate. The flow channel is separated from the cavity by at least a barrier formed along the cavity. Such a structure allows the cavity to be filled with a sample solution even in minute quantities. At the same time, the structure can provide a sample solution with a rapid temperature-control. The structure can therefore contribute to accelerated polymerase chain reaction.
摘要翻译：本发明提供了用于聚合酶链反应的试剂盒。该套件在衬底上具有空腔和流动通道。流动通道至少沿着空腔形成的屏障与空腔分离。这种结构允许空腔即使以微量数量填充样品溶液。同时，该结构可以提供具有快速温度控制的样品溶液。因此，该结构可能有助于加速聚合酶链反应。

94. 发明申请

US20060160097A1 Amplification reaction vessel, and method of manufacturing the same 有权
标题翻译：扩增反应容器及其制造方法
公开(公告)号：US20060160097A1
公开(公告)日：2006-07-20
申请号：US10984500
申请日：2004-11-09
申请人： Masaya Nakatani , Tetsuo Yukimasa
发明人： Masaya Nakatani , Tetsuo Yukimasa
IPC分类号： C12Q1/68 , C12P19/34 , C12M1/34
CPC分类号： B01L3/50851 , B01L3/502707 , B01L3/502715 , B01L7/52 , B01L2300/0816 , B01L2300/0822 , B01L2400/0406 , B01L2400/086
摘要： A nucleic acid amplification reaction vessel has a substrate, a cavity formed in the substrate, a cover plate for sealing the cavity, and a sample-injection inlet formed in the cover plate. The cavity includes a columnar structure connected to the cover plate or the substrate. The nucleic acid amplification reaction vessel allows fast temperature increase or decrease of sample liquid.
摘要翻译：核酸扩增反应容器具有基板，形成在基板中的空腔，用于密封空腔的盖板和形成在盖板上的样品注入口。空腔包括连接到盖板或基板的柱状结构。核酸扩增反应容器允许样品液体快速升高或降低。

95. 发明授权

US07018545B2 Component separating device, method of manufacturing the device, and method of separating fine solid component by using the device 有权
标题翻译：元件分离装置，制造装置的方法以及使用该装置分离细固体成分的方法
公开(公告)号：US07018545B2
公开(公告)日：2006-03-28
申请号：US10491753
申请日：2003-07-09
申请人： Masaya Nakatani
发明人： Masaya Nakatani
IPC分类号： B01D35/06
CPC分类号： G01N1/4077 , B01L3/5027
摘要： A components separation device including well (2) for containing a sample, being an object of separation, which well (2) is disposed on stage (1). Well (2) is fixed at only one point of the bottom on stage (1). Base (13) formed on stage (1) is further provided with an actuator for vibrating well (2).
摘要翻译：一种组件分离装置，包括用于容纳作为分离对象的样品的井（2），井（2）设置在载物台（1）上。井（2）固定在台架（1）底部的一个点上。形成在平台（1）上的基座（13）还设置有用于振动井（2）的致动器。

96. 发明申请

US20050000912A1 Component separating device, method of manufacturing the device, and method of separating fine solid component by using the device 有权
标题翻译：元件分离装置，制造装置的方法以及使用该装置分离细固体成分的方法
公开(公告)号：US20050000912A1
公开(公告)日：2005-01-06
申请号：US10491753
申请日：2003-07-09
申请人： Masaya Nakatani
发明人： Masaya Nakatani
IPC分类号： B01L3/00 , G01N1/28 , C02F1/34
CPC分类号： G01N1/4077 , B01L3/5027
摘要： A components separation device including well (2) for containing a sample, being an object of separation, which well (2) is disposed on stage (1). Well (2) is fixed at only one point of the bottom on stage (1). Base (13) formed on stage (1) is further provided with an actuator for vibrating well (2).
摘要翻译：一种组件分离装置，包括用于容纳作为分离对象的样品的井（2），井（2）设置在载物台（1）上。井（2）固定在台架（1）底部的一个点上。形成在平台（1）上的基座（13）还设置有用于振动井（2）的致动器。

97. 发明授权

US06554408B1 Fluid ejection device and process for the production thereof 失效
标题翻译：流体喷射装置及其制造方法
公开(公告)号：US06554408B1
公开(公告)日：2003-04-29
申请号：US09506751
申请日：2000-02-18
申请人： Katsumasa Miki , Masaya Nakatani , Isaku Kanno , Ryoichi Takayama , Koji Nomura
发明人： Katsumasa Miki , Masaya Nakatani , Isaku Kanno , Ryoichi Takayama , Koji Nomura
IPC分类号： B41J2045
CPC分类号： B41J2/1623 , B41J2/14233 , B41J2/161 , B41J2/1628 , B41J2/1631 , B41J2/1632 , B41J2/1646 , B41J2002/14387
摘要： A fluid ejection device, such as for an ink jet printer or the like, having increased increasing nozzle density. A through-hole (15) is provided in a glass substrate (18) to which a second silicon substrate (19) is directly bonded to form an ink outlet (14). The first silicon substrate (17) is etched to form a pressure chamber (12), an ink channel (13) and an ink inlet (16), and bonded directly to the glass substrate (18). A piezoelectric thin film (11), having a conductive, elastic body (20), is bonded to the first substrate covering the pressure chamber (12). The elastic body (20) is sandwiched between the piezoelectric thin film (11) and a resin layer (25). The second substrate (19) has a thickness of less than about 0.8 mm in a range of thickness comprising about 1.2 to about 1.9 times (rg-rs), wherein rg is the diameter of the wide end of the through-hole (15) and rs is the diameter of the narrow end of the through-hole (15).
摘要翻译：诸如用于喷墨打印机等的流体喷射装置具有增加的喷嘴密度的增加。在玻璃基板（18）上设置有通孔（15），第二硅基板（19）直接接合在该玻璃基板（18）上形成出墨口（14）。蚀刻第一硅衬底（17）以形成压力室（12），墨水通道（13）和墨水入口（16），并直接粘合到玻璃基底（18）上。具有导电弹性体（20）的压电薄膜（11）与覆盖压力室（12）的第一基板接合。弹性体（20）夹在压电薄膜（11）和树脂层（25）之间。第二基板（19）的厚度小于约0.8mm，其厚度范围为约1.2至约1.9倍（rg-rs），其中rg是通孔（15）的宽端的直径，并且rs是通孔（15）的窄端的直径。

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