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91. 发明申请

US20070276227A1 Method for locating a medical instrument during an intervention performed on the human body 有权
标题翻译：在对人体进行的干预中定位医疗器械的方法
公开(公告)号：US20070276227A1
公开(公告)日：2007-11-29
申请号：US11805215
申请日：2007-05-22
申请人： Jan Boese , Marcus Pfister
发明人： Jan Boese , Marcus Pfister
IPC分类号： A61B5/05
CPC分类号： A61B5/063 , A61B5/06 , A61B5/062 , A61B6/12 , A61B34/20 , A61B90/36 , A61B2034/2051 , A61B2090/376 , G06F19/00
摘要： The invention relates to a method for locating a medical instrument during an intervention performed on the human body using an X-ray image recording system and an electromagnetic locating system whose systems of coordinates have been or will be mutually registered, with a first item of positional information about the instrument being obtained continuously by means of the locating system and in each case two two-dimensional X-ray images positioned at an angle to each other being intermittently recorded by means of the X-ray image recording system, from which images a second item of positional information about the instrument is determined and compared with the first item of positional information, after which the first item of positional information will be corrected depending on the comparison result taking account of the second item of positional information obtained from the X-ray images.
摘要翻译：本发明涉及一种用于在使用X射线图像记录系统对人体进行的干预期间定位医疗器械的方法以及其坐标系统已经或将要相互注册的电磁定位系统，其中第一项位置关于通过定位系统连续获得的仪器的信息，并且在每种情况下，通过X射线图像记录系统间歇地记录彼此成角度定位的两个二维X射线图像，图像a 确定与仪器相关的位置信息的第二项，并将其与位置信息的第一项进行比较，之后根据从X轴获得的位置信息的第二项目考虑的比较结果来修正位置信息的第一项，射线图像。

92. 发明申请

US20070183569A1 Method for graphically following a movement of a medical instrument introduced into an object under examination 审中-公开
标题翻译：用于图形地跟随引入到检查对象中的医疗器械的移动的方法
公开(公告)号：US20070183569A1
公开(公告)日：2007-08-09
申请号：US11704410
申请日：2007-02-08
申请人： Jan Boese , Marcus Pfister
发明人： Jan Boese , Marcus Pfister
IPC分类号： G01N23/04 , H05G1/02
CPC分类号： A61B6/06 , A61B6/12 , A61B6/4441 , A61B6/466 , A61B6/5235 , A61B6/542
摘要： The invention relates to an apparatus and a method for graphically following movements of a medical instrument introduced into an object under examination, with a plurality of projection data sets being obtained from an x-ray beam passing through an examination area and delimited by a beam delimiting surface, in which a part of the medical instrument is guided, and with a three-dimensional image data set of the examination area being determined and represented graphically from the projection data sets. By determining three-dimensional image data sets successively with an image determination rate that is selected so that the movement of the medical instrument is able to be followed, the method and the apparatus can follow a moving medical instrument introduced into the examination area over the duration of a medical intervention and guarantee good accessibility to the object.
摘要翻译：本发明涉及一种用于图形化跟踪被引入到被检查物体中的医疗器械的运动的装置和方法，其中多个投影数据组从通过检查区域的X射线束获得，并由光束限定表面，其中医疗器械的一部分被引导，并且利用投影数据集图形地确定和表示检查区域的三维图像数据集。通过以选择的图像确定速率连续地确定三维图像数据集，使得能够遵循医疗器械的移动，该方法和装置可以在持续时间内引入到检查区域中的移动医疗器械进行医疗干预，保证对物体的可及性。

93. 发明申请

US20080031401A1 Method and apparatus for displaying a region to be examined of an examination object 审中-公开
标题翻译：用于显示检查对象的被检查区域的方法和装置
公开(公告)号：US20080031401A1
公开(公告)日：2008-02-07
申请号：US11704425
申请日：2007-02-08
申请人： Jan Boese , Marcus Pfister
发明人： Jan Boese , Marcus Pfister
IPC分类号： A61B6/03
CPC分类号： A61B6/504 , A61B6/022 , A61B6/06 , A61B6/4441 , A61B6/466 , A61B6/481
摘要： The invention relates to a method and an apparatus for spatially displaying a region to be examined of an examination object, which has an x-ray emitter which can be rotated about the examination object in order to generate an x-ray beams and an x-ray detector which can be rotated about the examination object in order to record a part of the x-ray beam penetrating the examination object, with a facility having an opening for fading-in a split beam being arranged at a distance from the x-ray emitter. By being able to adjust the opening and/or the distance of the fade-in facility, a method and an apparatus can be provided, with which the radiation exposure for an examination object is reduced.
摘要翻译：本发明涉及一种用于空间显示检查对象的区域的方法和装置，该检查对象具有可以围绕检查对象旋转的x射线发射器，以便产生x射线束和x射线束，射线检测器，其可围绕检查对象旋转，以便记录穿透检查对象的x射线束的一部分，具有用于衰减的分离光束的开口的设施设置在与x射线相距一定距离处发射器。通过能够调节淡入设备的开口和/或距离，可以提供一种减少检查对象的放射线暴露的方法和装置。

94. 发明授权

US07794446B2 Method of recording two-dimensional images of a perfused blood vessel 有权
标题翻译：记录灌注血管的二维图像的方法
公开(公告)号：US07794446B2
公开(公告)日：2010-09-14
申请号：US11062302
申请日：2005-02-18
申请人： Jan Boese , Martin Kleen
发明人： Jan Boese , Martin Kleen
IPC分类号： A61M31/00 , A61B6/00 , A61B1/12
CPC分类号： A61B5/6852 , A61B5/0066 , A61B5/0084
摘要： The invention relates to a method for recording two-dimensional images on the interior of a perfused blood vessel by means of optical coherence tomography using a catheter with an integrated imaging device, via which light is radiated and light reflected from the vascular wall is recorded, whereby a fluid containing a medium having a higher refractive index than blood plasma and/or cytoplasm is injected, via the catheter, into the vascular area to be recorded, to enable imaging to be carried out, whereby said fluid is a mixture of autologous blood and the medium.
摘要翻译：本发明涉及一种通过光学相干断层扫描在灌注血管内部记录二维图像的方法，该方法使用具有集成成像装置的导管，通过该导管照射光并从血管壁反射的光被记录，由此将含有比血浆和/或细胞质更高的折射率的介质的流体经由导管注入待记录的血管区域中，以使得能够进行成像，由此所述流体是自体血液的混合物和介质。

95. 发明申请

US20060058638A1 Method and device for the diagnosis and treatment of aortic aneurysms 审中-公开
标题翻译：用于主动脉瘤诊断和治疗的方法和装置
公开(公告)号：US20060058638A1
公开(公告)日：2006-03-16
申请号：US11222394
申请日：2005-09-08
申请人： Jan Boese , Martin Kleen , Klaus Klingenbeck-Regn , Michael Maschke
发明人： Jan Boese , Martin Kleen , Klaus Klingenbeck-Regn , Michael Maschke
IPC分类号： A61B5/05
CPC分类号： A61B6/504 , A61B5/055 , A61B6/032 , A61B6/507 , A61B6/541 , A61F2/07 , A61F2/90 , A61F2240/002
摘要： Method for the diagnosis and treatment of aortic aneurysms through representation of the affected area of the aorta by means of an imaging method and measurement of the image in order to produce a made-to-measure stent graft which is introduced into the aorta in the folded state and then expanded, a digital model of the aortic aneurysm being created from the images present as 3D volume data, from which digital model of the aortic aneurysm there is produced by means of iterative customizing software a digital model of the stent graft on the basis of which the stent graft is manufactured.
摘要翻译：用于通过成像方法表示主动脉瘤的受影响区域并且对图像进行测量来诊断和治疗主动脉瘤的方法，以便产生将被测量的支架移植物引入到折叠的主动脉中状态然后扩大，主动脉瘤的数字模型是从作为3D体积数据存在的图像创建的，其中主动脉瘤的数字模型通过迭代定制软件基于支架移植物的数字模型产生其中制造了支架植入物。

96. 发明申请

US20070055533A1 Method for protection and licensing of designs 审中-公开
标题翻译：设计保护和许可的方法
公开(公告)号：US20070055533A1
公开(公告)日：2007-03-08
申请号：US11208194
申请日：2005-08-19
申请人： Martin Kleen , Jan Boese
发明人： Martin Kleen , Jan Boese
IPC分类号： G06Q99/00
CPC分类号： G06Q30/06
摘要： A method for protecting a custom design of a product provides that a manufacturer of the custom designed product agrees not to make the product according to the design for others in return for a payment from the designer. The protection, which is between the manufacturer and the designer, may be for identical designs or for designs having a scope of similarity. The payment for the protection may be a one time payment or may be periodic. The manufacturer may in some instances license the design to others and pay the designer a fee for doing so.
摘要翻译：保护产品的定制设计的方法规定，定制设计产品的制造商同意不按照他人的设计来制造产品以换取设计者的付款。制造商和设计师之间的保护可以用于相同的设计或具有相似范围的设计。保护付款可能是一次性付款或可能是定期付款。制造商在某些情况下可能将设计许可给他人，并向设计师支付费用。

97. 发明授权

US10719986B2 Method and system for virtual percutaneous valve implantation 有权
公开(公告)号：US10719986B2
公开(公告)日：2020-07-21
申请号：US12975714
申请日：2010-12-22
申请人： Dominik Zaeuner , Razvan Ioan Ionasec , Bogdan Georgescu , Yefeng Zheng , Dorin Comaniciu , Ingmar Voigt , Jan Boese
发明人： Dominik Zaeuner , Razvan Ioan Ionasec , Bogdan Georgescu , Yefeng Zheng , Dorin Comaniciu , Ingmar Voigt , Jan Boese
IPC分类号： G06T17/00 , G06T19/00 , G16H50/50 , G06F19/00
摘要： A method and system for virtual percutaneous valve implantation is disclosed. A patient-specific anatomical model of a heart valve is estimated based on 3D cardiac medical image data and an implant model representing a valve implant is virtually deployed into the patient-specific anatomical model of the heart valve. A library of implant models, each modeling geometrical properties of a corresponding valve implant, is maintained. The implant models maintained in the library are virtually deployed into the patient specific anatomical model of the heart valve to select an implant type and size and deployment location and orientation for percutaneous valve implantation.

98. 发明授权

US09014423B2 Method and system for catheter tracking in fluoroscopic images using adaptive discriminant learning and measurement fusion 有权
标题翻译：使用自适应判别学习和测量融合的荧光镜图像中导管跟踪的方法和系统
公开(公告)号：US09014423B2
公开(公告)日：2015-04-21
申请号：US13412882
申请日：2012-03-06
申请人： Peng Wang , Yefeng Zheng , Matthias John , Jan Boese , Gareth Funka-Lea , Dorin Comaniciu
发明人： Peng Wang , Yefeng Zheng , Matthias John , Jan Boese , Gareth Funka-Lea , Dorin Comaniciu
IPC分类号： G06K9/00 , A61B6/00 , A61B6/12 , G06T7/20
CPC分类号： A61B6/487 , A61B6/12 , A61B6/503 , G06T7/246 , G06T2207/10016 , G06T2207/10064 , G06T2207/20076 , G06T2207/20081 , G06T2207/30021 , G06T2207/30048
摘要： A method and system for adaptive discriminant learning and measurement fusion for image based catheter tracking is disclosed. An adaptive discriminant model is trained online based on a tracked object, such as a pigtail catheter tip, in at least one previous frame of a fluoroscopic image sequence. The object is tracked in the current frame of the fluoroscopic image sequence based at least on the adaptive discriminant model trained online. The object may be tracked in the current frame based on a fusion of three types of measurement models including the adaptive discriminant model trained online, an object detection model trained offline, and an online appearance model.
摘要翻译：公开了一种用于基于图像的导管跟踪的自适应判别学习和测量融合的方法和系统。在荧光镜像图像序列的至少一个先前帧中，基于跟踪对象（例如尾纤导管尖端）在线训练自适应判别模型。至少基于在线训练的自适应判别模型，在透视图像序列的当前帧中跟踪对象。基于三种类型的测量模型的融合，可以在当前帧中跟踪对象，包括在线训练的自适应判别模型，离线训练的对象检测模型和在线外观模型。

99. 发明授权

US08428319B2 Automatic measurement of morphometric and motion parameters of the coronary tree from a rotational X-ray sequence 有权
标题翻译：从旋转X射线序列自动测量冠状动脉树的形态和运动参数
公开(公告)号：US08428319B2
公开(公告)日：2013-04-23
申请号：US12764225
申请日：2010-04-21
申请人： Yanghai Tsin , Klaus J. Kirchberg , Günter Lauritsch , Chenyang Xu , Jan Boese , Rui Liao
发明人： Yanghai Tsin , Klaus J. Kirchberg , Günter Lauritsch , Chenyang Xu , Jan Boese , Rui Liao
IPC分类号： G06K9/00
CPC分类号： G06T7/251 , G06T7/60 , G06T7/62 , G06T2207/10116 , G06T2207/30101 , G06T2207/30172
摘要： Automatic measurement of morphometric and motion parameters of a coronary target includes extracting reference frames from input data of a coronary target at different phases of a cardiac cycle, extracting a three-dimensional centerline model for each phase of the cardiac cycle based on the references frames and projection matrices of the coronary target, tracking a motion of the coronary target through the phases based on the three-dimensional centerline models, and determining a measurement of morphologic and motion parameters of the coronary target based on the motion.
摘要翻译：自动测量冠状动脉靶标的形态测量和运动参数包括：在心脏周期的不同阶段从冠状动脉靶的输入数据提取参考帧，基于参考帧提取心动周期的每个相位的三维中心线模型，以及冠状动脉靶的投影矩阵，基于三维中心线模型跟踪通过相位的冠状动脉靶的运动，以及基于运动确定冠状动脉靶标的形态和运动参数的测量。

100. 发明授权

US08428221B2 Medical x-ray acquisition system 有权
标题翻译：医疗x射线采集系统
公开(公告)号：US08428221B2
公开(公告)日：2013-04-23
申请号：US12893189
申请日：2010-09-29
申请人： Jan Boese , Michael Maschke
发明人： Jan Boese , Michael Maschke
IPC分类号： H01J35/06 , H05G1/02
CPC分类号： H01J35/065 , A61B6/4007 , A61B6/4028 , A61B6/4441 , A61B6/4458 , A61B6/4464 , A61B6/548 , H01J2235/068
摘要： A medical x-ray acquisition system has an x-ray source and an x-ray detector, the x-ray source having at least one field emission radiator with at least one field emission cathode. The field emission cathode can be formed by a nanostructured material with carbon nanotubes.
摘要翻译：医用x射线摄取系统具有x射线源和x射线检测器，该x射线源具有至少一个具有至少一个场发射阴极的场发射辐射器。场发射阴极可以由具有碳纳米管的纳米结构材料形成。

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