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91. 发明授权

US08735153B2 Modulation of stem cells using zinc finger proteins 有权
标题翻译：使用锌指蛋白调节干细胞
公开(公告)号：US08735153B2
公开(公告)日：2014-05-27
申请号：US10490787
申请日：2002-09-24
申请人： Michael Moore , Timothy Farries , Trevor Collingwood , Fyodor Urnov , Elizabeth J. Wolffe
发明人： Alan P. Wolffe , Michael Moore , Timothy Farries , Trevor Collingwood , Fyodor Urnov
IPC分类号： C12N5/00 , C12N5/02 , C12N15/63 , A01N63/00 , C07H21/04
CPC分类号： C12N15/85 , A61K35/12 , C07H21/04 , C12N5/0606 , C12N15/62 , C12N15/63 , C12N2501/40 , C12N2503/02 , G01N33/5008 , G01N33/5023 , G01N33/5073
摘要： Methods and compositions for modifying stem cells using one or more ZFPs are disclosed. Such methods and compositions are useful for facilitating processes such as, for example, dedifferentiating cells, differentiating stems cells into the desired phenotype, propagating stem cells and/or facilitating cloning.
摘要翻译：公开了使用一种或多种ZFP修饰干细胞的方法和组合物。这些方法和组合物可用于促进诸如分化细胞，将茎细胞分化成所需表型，增殖干细胞和/或促进克隆的过程。

92. 发明申请

US20130085551A1 DEVICES, SYSTEMS AND METHODS FOR TREATING PAIN WITH ELECTRICAL STIMULATION 有权
公开(公告)号：US20130085551A1
公开(公告)日：2013-04-04
申请号：US13570004
申请日：2012-08-08
申请人： Thomas Jerome Bachinski , Dain Silvola , Michael Moore , Jay Dave , Joseph Winn
发明人： Thomas Jerome Bachinski , Dain Silvola , Michael Moore , Jay Dave , Joseph Winn
IPC分类号： A61N1/36
CPC分类号： A61N1/36021 , A61H23/02 , A61H39/002 , A61H39/04 , A61H39/08 , A61H2201/0153 , A61H2201/0157 , A61H2201/0184 , A61H2201/0188 , A61H2201/10 , A61H2201/1604 , A61H2201/1609 , A61H2201/1635 , A61H2201/1685 , A61H2201/5007 , A61H2201/501 , A61H2201/5012 , A61H2201/5028 , A61H2201/5035 , A61H2201/5043 , A61H2201/5048 , A61H2201/5082 , A61H2205/02 , A61H2205/022 , A61H2205/04 , A61H2205/062 , A61H2205/065 , A61H2205/081 , A61H2205/10 , A61H2205/12 , A61H2230/065 , A61H2230/605 , A61H2230/655 , A61N1/0456 , A61N1/36014 , A61N1/37264
摘要： Devices, systems and methods are provided for treating migraine headaches and other conditions by non-invasive electrical stimulation of nerves and other tissue. A hand-held device includes a housing with a controller having a signal generator, an electrode for delivering electrical signals, and a conductive surface configured as a return path for the electrical signals. In certain implementations, the electrode is repositionable with respect to the housing. The patient can self-apply the hand-held device by pressing it against areas in need of pain relief. The device may include a pressure-sensitive gating switch to control delivery of the stimulation therapy. In certain embodiments, the electrode is a rollerball electrode. The device may include a chamber for retaining and dispensing conductive gel to the therapy site. In certain approaches, the device includes an electrode support for coupling an electrical stimulation system to the head for hands-free electrical stimulation therapy.

93. 发明申请

US20120322530A1 SYSTEM AND METHOD FOR ELECTRONIC BINGO 审中-公开
标题翻译：电子BINGO系统与方法
公开(公告)号：US20120322530A1
公开(公告)日：2012-12-20
申请号：US13163210
申请日：2011-06-17
申请人： Michael Moore
发明人： Michael Moore
IPC分类号： G06F17/00
CPC分类号： G07F17/3276
摘要： A method for facilitating play of a bingo game via one or more play consoles is disclosed including receiving a user indication at a first console that a first user desires to enter a bingo game, receiving a user indication at a second console that a second user desires to enter the bingo game, and only after receiving a user indication at a second console that a second user desires to enter the bingo game, starting the bingo game. A space on a user's card is marked as being designated if and only if the user positively selects the space as designated. Moreover, a player is designated as bingo winner if and only if the player in question has selected a winning pattern of designated spaces and in addition has identified themselves as a bingo winner. The plurality of player consoles may be located in a common area or may be remote from one another. The player consoles may be personal computers, dedicated bingo consoles or other electronic devices.
摘要翻译：公开了一种便于通过一个或多个播放控制台播放宾果游戏的方法，包括在第一控制台处接收用户指示第一用户希望进入宾果游戏，在第二控制台处接收第二用户期望的用户指示进入宾果游戏，并且只有在第二控制台接收到用户指示第二用户希望进入宾果游戏之后，开始宾果游戏。当且仅当用户正确选择指定的空格时，用户卡上的空格被标记为被指定。此外，当且仅当所述玩家已经选择了指定空间的获胜模式，并且还将自己识别为宾果获胜者时，玩家被指定为宾果获胜者。多个播放器控制台可以位于公共区域中或者可以彼此远离。播放器控制台可以是个人计算机，专用宾果游戏机或其他电子设备。

94. 发明申请

US20120320159A1 Apparatus And Method To Automatically Distinguish Between Contamination And Degradation Of An Article 有权
标题翻译：自动区分污染和降解物品的装置和方法
公开(公告)号：US20120320159A1
公开(公告)日：2012-12-20
申请号：US13523992
申请日：2012-06-15
申请人： Myra A. Torres , Abhijit Bhoite , Nikhil Beke , Kevin Patrick McCormick , Timothy Duffy , Jeremy W. Sheaffer , Maksim Bobrov , Michael Moore
发明人： Myra A. Torres , Abhijit Bhoite , Nikhil Beke , Kevin Patrick McCormick , Timothy Duffy , Jeremy W. Sheaffer , Maksim Bobrov , Michael Moore
IPC分类号： G06K9/62 , H04N13/02
CPC分类号： G06T7/0006 , G06T7/571 , G06T2207/10148 , G06T2207/20064 , G06T2207/20221
摘要： An inspection apparatus includes an imaging unit producing image signals; a processing unit for receiving the image signal; the imaging unit producing a stack of images of an article at different focal lengths in response to the processing unit; the processing unit generating a depth map from the stack of images; the processing unit analyzing the depth map to derive a depth profile of an object of interest; the processing unit determining a surface mean for the article from the stack of images; and the processing unit characterizing the article as degraded or contaminated in response to the depth profile and the surface mean.
摘要翻译：检查装置包括产生图像信号的成像单元; 处理单元，用于接收图像信号; 所述成像单元响应于所述处理单元产生不同焦距的物品的一叠图像; 所述处理单元从所述图像堆生成深度图; 所述处理单元分析所述深度图以导出感兴趣对象的深度轮廓; 所述处理单元从所述图像堆确定所述物品的表面平均值; 以及处理单元，其特征在于，根据深度轮廓和表面平均值，物品被降解或污染。

95. 发明申请

US20120091692A1 RECEIVER DEVICE FOR ENGAGING A LANDING GEAR ADAPTER WITH A TUG 有权
标题翻译：用于连接带有拖把的接地齿轮适配器的接收装置
公开(公告)号：US20120091692A1
公开(公告)日：2012-04-19
申请号：US13273152
申请日：2011-10-13
申请人： Michael Moore
发明人： Michael Moore
IPC分类号： B60D1/167 , F16B17/00 , B60D1/14
CPC分类号： B60D1/01 , B60D1/167 , B64F1/224 , Y10T403/60 , Y10T403/70
摘要： A receiver device for engaging a landing gear adapter unit with a tug. In exemplary embodiments, the adapter may include a tow bar with a neck portion between a pair of spaced arm portions. The receiver device forms a travel path boundary for the neck portion and is configured to be complementary with and to engage the neck portion. A mounting portion is provided for mounting the receiver device on the tug in an operative configuration relative to a landing gear-receiving base thereon. At least one releasable locking member is positioned along the travel path to interrupt travel of the neck portion. The locking member is movable between a first unlocked position and a second locked position. Further, in the second locked position, the locking member is configured to lock the mounting portion in the operative configuration.
摘要翻译：用于将起落架适配器单元与拖轮接合的接收器装置。在示例性实施例中，适配器可以包括在一对间隔开的臂部之间具有颈部的拖杆。接收器装置形成颈部的行进路径边界，并且构造成与颈部互补并接合颈部。提供安装部分，用于相对于其上的起落架接收基座以相对于起落架接收基座的操作构造将接收器装置安装在拖船上。沿着行进路径定位至少一个可释放的锁定构件以中断颈部的行进。锁定构件可在第一解锁位置和第二锁定位置之间移动。此外，在第二锁定位置，锁定构件被构造成将安装部分锁定在操作构造中。

96. 发明授权

US07947469B2 Modulation of HIV infection 有权
标题翻译：调控艾滋病毒感染
公开(公告)号：US07947469B2
公开(公告)日：2011-05-24
申请号：US10470065
申请日：2002-01-22
申请人： Michael Moore , Mark Isalan , Lindsey Reynolds , Christopher Ullman , John Girdlestone , Christophe Demaison , Yen Choo
发明人： Michael Moore , Mark Isalan , Lindsey Reynolds , Christopher Ullman , John Girdlestone , Christophe Demaison , Yen Choo
IPC分类号： C12P21/04 , C12P21/06 , C12Q1/68 , C12N5/00 , C07H21/04
CPC分类号： C07K14/4703 , A61K38/00
摘要： Disclosed herein are methods and compositions for modulating HIV infection by regulating expression of one or more receptors.
摘要翻译：本文公开了通过调节一种或多种受体的表达来调节HIV感染的方法和组合物。

97. 发明申请

US20080115299A1 Automatic Swimming Pool Cleaners and Components Thereof 有权
标题翻译：自动游泳池清洁剂及其组件
公开(公告)号：US20080115299A1
公开(公告)日：2008-05-22
申请号：US12020610
申请日：2008-01-28
申请人： Hendrikus van der Meijden , Michael Moore , Peter Harrison , Alexis Wadman , Mark Bauckman
发明人： Hendrikus van der Meijden , Michael Moore , Peter Harrison , Alexis Wadman , Mark Bauckman
IPC分类号： E04H4/16 , F03B11/00
CPC分类号： E04H4/1663 , Y10T137/8593 , Y10T137/86389 , Y10T137/86413
摘要： Devices for cleaning vessels, especially swimming pools, are discussed. The devices may include a non-linear flow path in a gap surrounding an in-line valve. This non-linearity permits lengths of concentric pipes forming the gap to be decreased without sacrificing operational performance of the devices. Valves forming parts of the cleaning devices may be diaphragms but shaped, sized, reinforced, or configured differently than existing valves and may have collapsible segments whose interior shape resembles an ellipse in transverse cross-section. Co-molding of diaphragms and pipes may occur, and inner and outer cups may be used to fix relative positions of various components of the devices.
摘要翻译：讨论了用于清洁船只，特别是游泳池的设备。这些装置可以包括围绕在线阀的间隙中的非线性流动路径。这种非线性允许形成间隙的同心管的长度减小而不牺牲装置的操作性能。形成清洁装置的部件的阀可以是隔膜，但是成形，尺寸，加强或不同于现有阀的构造，并且可以具有内部形状在横截面中类似于椭圆的可折叠段。可能发生隔膜和管道的共模塑，并且可以使用内杯和外杯来固定装置的各种部件的相对位置。

98. 发明申请

US20080033330A1 APPARATUS, SYSTEM, AND METHOD FOR PROTECTING AND TREATING A TRAUMATIC WOUND 有权
标题翻译：装置，系统和保护和处理交通工具的方法
公开(公告)号：US20080033330A1
公开(公告)日：2008-02-07
申请号：US11834400
申请日：2007-08-06
申请人： Michael Moore
发明人： Michael Moore
IPC分类号： A61F13/00 , A61B5/00
CPC分类号： A61B5/445 , A61B5/02055 , A61B5/03 , A61B5/0816 , A61F13/0216 , A61F13/0246 , A61M1/0084 , A61M1/0088
摘要： An apparatus, system, and method are disclosed for protection, depressurization, and treatment of a traumatic wound. The disclosed apparatus comprises a flexible patch with an elevated portion configured to accommodate multiple connectors at least one of which is configured to interface with a two-way valve.
摘要翻译：公开了用于保护，减压和治疗创伤性伤口的装置，系统和方法。所公开的装置包括具有升高部分的柔性贴片，其被配置为容纳多个连接器，其中至少一个连接器构造成与二通阀相接合。

99. 发明申请

US20060054229A1 Valve assemblies principally for automatic swimming pool cleaner 审中-公开
标题翻译：阀组件主要用于自动游泳池清洁
公开(公告)号：US20060054229A1
公开(公告)日：2006-03-16
申请号：US10939579
申请日：2004-09-13
申请人： Hendrikus van der Meijden , Peter Harrison , Michael Moore , Mark Bauckman
发明人： Hendrikus van der Meijden , Peter Harrison , Michael Moore , Mark Bauckman
IPC分类号： F16K15/14
CPC分类号： E04H4/1663 , F16K15/147 , Y10T137/7885
摘要： Detailed are valves principally useful for automatic swimming pool cleaners. The valves may be made of flexible material and, typically, are generally tubular in shape. Mouths of the valves may be divided into two or more parts, with certain versions having three lobes. These configurations enable larger debris to pass through the valves.
摘要翻译：详细的阀门主要用于自动游泳池清洁剂。阀可以由柔性材料制成，并且通常通常为管状的形状。阀的口可以分为两个或更多个部分，某些形式具有三个凸角。这些配置使得较大的碎屑能够通过阀门。

100. 发明申请

US20060032539A1 Automatic swimming pool cleaners and components thereof 有权
公开(公告)号：US20060032539A1
公开(公告)日：2006-02-16
申请号：US10917587
申请日：2004-08-13
申请人： Hendrikus Johannes Meijden , Michael Moore , Peter Harrison , Alexis Adrian Wadman , Mark Bauckman
发明人： Hendrikus Johannes Meijden , Michael Moore , Peter Harrison , Alexis Adrian Wadman , Mark Bauckman
IPC分类号： F16K31/48
CPC分类号： E04H4/1663 , Y10T137/8593 , Y10T137/86389 , Y10T137/86413
摘要： Devices for cleaning vessels, especially swimming pools, are discussed. The devices may include a non-linear flow path in a gap surrounding an in-line valve. This non-linearity permits lengths of concentric pipes forming the gap to be decreased without sacrificing operational performance of the devices. Valves forming parts of the cleaning devices may be diaphragms but shaped, sized, reinforced, or configured differently than existing valves and may have collapsible segments whose interior shape resembles an ellipse in transverse cross-section. Co-molding of diaphragms and pipes may occur, and inner and outer cups may be used to fix relative positions of various components of the devices.

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