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91. 发明授权

US07489970B2 Management of neurostimulation therapy using parameter sets 有权
标题翻译：使用参数集管理神经刺激治疗
公开(公告)号：US07489970B2
公开(公告)日：2009-02-10
申请号：US10406040
申请日：2003-04-02
申请人： Michael T. Lee , Daniel K. Vinup , Steven M. Goetz
发明人： Michael T. Lee , Daniel K. Vinup , Steven M. Goetz
IPC分类号： A61N1/36
CPC分类号： A61N1/36071 , A61N1/37247 , G06F19/00
摘要： An implantable medical device delivers neurostimulation therapy to a patient according to a parameter set. A parameter set may consist of a number of programs that are delivered substantially simultaneously. When programming the implantable medical device for the patient, a clinician programmer may maintain a session log for the patient that includes a listing of programs delivered to the patient and rating information provided by a clinician and the patient for programs of the list. The listing may be ordered according to the rating information in order to facilitate the selection of programs for a parameter set. A program library that may include particularly effective programs organized according to a directory structure may be stored in a memory. One or both of the implantable medical device and a patient programmer may store usage information that provides an objective and accurate record of therapy use by the patient, and allows a clinician to later improve the therapy based on the usage information.
摘要翻译：植入式医疗装置根据参数组向患者传递神经刺激疗法。参数集可以包括大量同时传送的多个节目。当编程用于患者的可植入医疗装置时，临床医生程序员可以维护患者的会话日志，其包括递送给患者的程序的列表以及由临床医生和患者提供的用于该列表的程序的评估信息。可以根据评级信息对列表进行排序，以便于选择参数集的程序。可以包括根据目录结构组织的特别有效的程序的程序库可以存储在存储器中。可植入医疗装置和患者编程器中的一个或两个可以存储提供患者的治疗使用的客观和准确记录的使用信息，并且允许临床医生随后基于使用信息改进治疗。

92. 发明申请

US20080103552A1 Controller for obtaining prescriptive analysis of functionality of implantable medical device leads, system and method therefore 审中-公开
标题翻译：用于获得可植入医疗器械引线功能的规范性分析的控制器，因此系统和方法
公开(公告)号：US20080103552A1
公开(公告)日：2008-05-01
申请号：US11590741
申请日：2006-10-31
申请人： Steven M. Goetz , Todd V. Smith , Nathan A. Torgerson , Warren W. Ball
发明人： Steven M. Goetz , Todd V. Smith , Nathan A. Torgerson , Warren W. Ball
IPC分类号： A61N1/36
CPC分类号： A61N1/37247 , A61N1/0551 , A61N1/36185
摘要： Method, controller and system for an implantable medical device having a plurality of electrodes, the implantable medical device capable of delivering therapeutic stimulation to a patient, comprising a control module, a user interface operatively coupled to the control module, the user interface providing control of the control module by a medical professional or other user, and an electrode interface operatively coupled between the plurality of electrodes and the control module. The control module uses the electrode interface to obtain a plurality of measurements of impedance values for a plurality of selected pairs of individual ones of the plurality of electrodes. The control module determines a prescriptive analysis using the plurality of measurements of impedance values of the selected pairs of individual ones of the plurality of electrodes comparative to a range, and the user interface displays the prescriptive analysis.
摘要翻译：用于具有多个电极的可植入医疗装置的方法，控制器和系统，所述可植入医疗装置能够向患者递送治疗刺激，所述可植入医疗装置包括控制模块，可操作地耦合到所述控制模块的用户界面，所述用户界面提供医疗专业人员或其他用户的控制模块，以及可操作地耦合在多个电极和控制模块之间的电极接口。所述控制模块使用所述电极接口来获得所述多个电极中的多个所选择的对中的多个所选对的多个测量值。所述控制模块使用与所述多个电极中所选择的所述多个电极对中的所选择的一对电极的阻抗值的多个测量值相对于一个范围来确定规定性分析，并且所述用户界面显示所述规定性分析。

93. 发明申请

US20070203539A1 User interface with 2D views for configuring stimulation therapy 有权
标题翻译：用户界面具有2D视图，用于配置刺激疗法
公开(公告)号：US20070203539A1
公开(公告)日：2007-08-30
申请号：US11591178
申请日：2006-10-31
申请人： Richard T. Stone , Warren W. Ball , Carl D. Wahlstrand , Steven M. Goetz , Lynn M. Otten
发明人： Richard T. Stone , Warren W. Ball , Carl D. Wahlstrand , Steven M. Goetz , Lynn M. Otten
IPC分类号： A61N1/00
CPC分类号： A61N1/0529 , A61N1/0531 , A61N1/0534 , A61N1/0553 , A61N1/3605 , A61N1/36082 , A61N1/37247
摘要： The disclosure describes a method and system that allows a user to configure electrical stimulation therapy by defining a stimulation field. After a stimulation lead is implanted in a patient, a clinician manipulates a stimulation field on the display to encompass desired anatomical regions of the patient. In this manner, the clinician determines which anatomical regions to stimulate, and the system generates the necessary stimulation parameters. In some cases, a lead icon representing the implanted lead is displayed to show the clinician where the lead is relative to anatomical regions of the patient.
摘要翻译：本公开描述了允许用户通过定义刺激场来配置电刺激治疗的方法和系统。在刺激引线植入患者体内之后，临床医生操纵显示器上的刺激场以包围病人的所需解剖区域。以这种方式，临床医生确定要刺激的解剖区域，并且系统产生必要的刺激参数。在一些情况下，显示代表植入引线的引线图标，以显示临床医师，其中引线相对于患者的解剖区域。

94. 发明授权

US07252090B2 Selection of neurostimulator parameter configurations using neural network 有权
标题翻译：使用神经网络选择神经刺激器参数配置
公开(公告)号：US07252090B2
公开(公告)日：2007-08-07
申请号：US10767922
申请日：2004-01-29
申请人： Steven M. Goetz
发明人： Steven M. Goetz
IPC分类号： A61N1/36
CPC分类号： A61N1/37252 , A61N1/3605 , A61N1/36071 , Y10S128/925
摘要： In general, the invention is directed to a technique for selection of parameter configurations for a neurostimulator using neural networks. The technique may be employed by a programming device to allow a clinician to select parameter configurations, and then program an implantable neurostimulator to deliver therapy using the selected parameter configurations. The parameter configurations may include one or more of a variety of parameters, such as electrode configurations defining electrode combinations and polarities for an electrode set implanted in a patient. The electrode set may be carried by one or more implanted leads that are electrically coupled to the neurostimulator. In operation, the programming device executes a parameter configuration search algorithm to guide the clinician in the selection of parameter configurations. The search algorithm relies on a neural network that identifies potential optimum parameter configurations.
摘要翻译：通常，本发明涉及一种用于使用神经网络选择神经刺激器的参数配置的技术。该技术可以由编程设备使用以允许临床医生选择参数配置，然后编程可植入神经刺激器以使用所选择的参数配置递送治疗。参数配置可以包括各种参数中的一个或多个，例如限定电极组合的电极配置和用于植入患者体内的电极组的极性。电极组可以由与神经刺激器电耦合的一个或多个注入引线承载。在操作中，编程设备执行参数配置搜索算法以引导临床医生选择参数配置。搜索算法依赖于识别潜在最佳参数配置的神经网络。

95. 发明授权

US07169144B2 Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue 有权
公开(公告)号：US07169144B2
公开(公告)日：2007-01-30
申请号：US10699548
申请日：2003-10-31
申请人： Michael F. Hoey , Mark A. Christopherson , Steven M. Goetz
发明人： Michael F. Hoey , Mark A. Christopherson , Steven M. Goetz
IPC分类号： A61B18/18
CPC分类号： A61B18/18 , A61B18/1206 , A61B18/1233 , A61B18/14 , A61B18/1402 , A61B18/1815 , A61B2018/00029 , A61B2018/00196 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00779 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00875 , A61B2018/1213 , A61B2018/1253 , A61B2018/1417 , A61B2018/1472 , A61B2018/1475 , A61B2218/002 , A61B2218/007
摘要： The present invention provides an apparatus and a method for producing a virtual electrode within or upon a tissue to be treated with radio frequency alternating electric current, such tissues including but not limited to liver, lung, cardiac, prostate, breast, and vascular tissues and neoplasms. An apparatus in accord with the present invention includes a supply of a conductive or electrolytic fluid to be provided to the patient, an alternating current generator, and a processor for creating, maintaining, and controlling the ablation process by the interstitial or surficial delivery of the fluid to a tissue and the delivery of electric power to the tissue via the virtual electrode. A method in accord with the present invention includes delivering a conductive fluid to a predetermined tissue ablation site for a predetermined time period, applying a predetermined power level of radio frequency current to the tissue, monitoring at least one of several parameters, and adjusting either the applied power and/or the fluid flow in response to the measured parameters.

96. 发明授权

US06985088B2 Telemetry module with configurable data layer for use with an implantable medical device 有权
公开(公告)号：US06985088B2
公开(公告)日：2006-01-10
申请号：US10099786
申请日：2002-03-15
申请人： Steven M. Goetz , Gregory Pat Spar
发明人： Steven M. Goetz , Gregory Pat Spar
IPC分类号： H04Q9/00
CPC分类号： A61N1/37264 , A61N1/3605 , A61N1/37211 , A61N1/37252 , H04Q9/04
摘要： Disclosed is a method and apparatus for configuring an external device so that may communicate with and an implantable medical device in accordance with a desired telemetry protocols. The external device utilizes a telemetry module can be loaded with a protocol driver necessary for communicating with the implantable medical device. Once the desired protocol driver has been installed, the telemetry module and its associated external device, e.g., a physician programmer, are enabled to communicate with the implantable medical device.

97. 发明授权

US06736810B2 Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue 有权
标题翻译：用于创建，维持和控制用于消融组织的虚拟电极的装置和方法
公开(公告)号：US06736810B2
公开(公告)日：2004-05-18
申请号：US09903296
申请日：2001-07-11
申请人： Michael F. Hoey , Mark A. Christopherson , Steven M. Goetz
发明人： Michael F. Hoey , Mark A. Christopherson , Steven M. Goetz
IPC分类号： A61B1818
CPC分类号： A61B18/18 , A61B18/1206 , A61B18/1233 , A61B18/14 , A61B18/1402 , A61B18/1815 , A61B2018/00029 , A61B2018/00196 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00779 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00875 , A61B2018/1213 , A61B2018/1253 , A61B2018/1417 , A61B2018/1472 , A61B2018/1475 , A61B2218/002 , A61B2218/007
摘要： The present invention provides an apparatus and a method for producing a virtual electrode within or upon a tissue to be treated with radio frequency alternating electric current, such tissues including but not limited to liver, lung, cardiac, prostate, breast, and vascular tissues and neoplasms. An apparatus in accord with the present invention includes a supply of a conductive or electrolytic fluid to be provided to the patient, an alternating current generator, and a processor for creating, maintaining, and controlling the ablation process by the interstitial or surficial delivery of the fluid to a tissue and the delivery of electric power to the tissue via the virtual electrode. A method in accord with the present invention includes delivering a conductive fluid to a predetermined tissue ablation site for a predetermined time period, applying a predetermined power level of radio frequency current to the tissue, monitoring at least one of several parameters, and adjusting either the applied power and/or the fluid flow in response to the measured parameters.
摘要翻译：本发明提供了一种用于在射频交流电流处理的组织内或之上产生虚拟电极的装置和方法，所述组织包括但不限于肝脏，肺，心脏，前列腺，乳腺和血管组织，以及肿瘤。根据本发明的装置包括供给要提供给患者的导电或电解液，交流发生器和用于通过间隔或表面递送来产生，维持和控制消融过程的处理器流体到组织并经由虚拟电极向组织递送电力。根据本发明的方法包括将导电流体递送到预定的组织消融部位预定的时间段，向组织施加预定功率水平的射频电流，监测几个参数中的至少一个，并且调整响应于测量的参数施加的功率和/或流体流量。

98. 发明授权

US10204706B2 User interface for optimizing energy management in a neurostimulation system 有权
公开(公告)号：US10204706B2
公开(公告)日：2019-02-12
申请号：US12771475
申请日：2010-04-30
申请人： Jon P. Davis , Steven M. Goetz , Nathan A. Torgerson , Ashish Singal , Lynn A. Davenport , Rajeev M. Sahasrabudhe , Shyam Gokaldas , Joel A. Anderson , Leroy L. Perz , Scott E. Straka
发明人： Jon P. Davis , Steven M. Goetz , Nathan A. Torgerson , Ashish Singal , Lynn A. Davenport , Rajeev M. Sahasrabudhe , Shyam Gokaldas , Joel A. Anderson , Leroy L. Perz , Scott E. Straka
IPC分类号： A61N1/08 , G16H40/63 , G06F19/00
摘要： In one aspect, a programmer for an implantable medical device comprises a user interface that receives user input corresponding to one or more selected stimulation therapy parameters for delivering stimulation therapy to a patient with the implantable medical device and presents an energy consumption estimate of a power source based on the selected stimulation therapy parameters; and a processor that determines one or more programming options that, if selected, would alter the selected stimulation therapy parameters and reduce the energy consumption estimate. The user interface presents at least one of the programming options to reduce the energy consumption estimate to the user with an indication that user selection of one or more of the presented programming options would alter the selected stimulation therapy parameters to reduce energy consumption of the implantable medical device.

99. 发明授权

US09814885B2 Stimulation electrode selection 有权
公开(公告)号：US09814885B2
公开(公告)日：2017-11-14
申请号：US12768403
申请日：2010-04-27
申请人： Gabriela C. Molnar , Steven M. Goetz , Andrew N. Csavoy
发明人： Gabriela C. Molnar , Steven M. Goetz , Andrew N. Csavoy
IPC分类号： A61N1/36 , A61N1/05 , A61N1/08 , A61N1/372
CPC分类号： A61N1/36185 , A61N1/0529 , A61N1/08 , A61N1/37247
摘要： One or more stimulation electrodes may be selected based on a bioelectrical signal sensed in a brain of a patient with a sense electrode combination that comprises at least one electrode and a physiological model that indicates one or more anatomical structures of the brain of the patient that are proximate the implanted at least one electrode. In some examples, the bioelectrical brain signal indicates which electrodes are located closest to a target tissue site. The physiological model can be generated based on a location of implanted at least one electrode within a patient and patient anatomy data, which can, for example, indicate one or more characteristics of patient tissue proximate to the implanted at least one electrode. In some example, the physiological model includes a therapy field model that represents a region of the tissue of the patient to which therapy is delivered via a selected set of electrodes.

100. 发明授权

US09723987B2 Remote calibration of an implantable patient sensor 有权
公开(公告)号：US09723987B2
公开(公告)日：2017-08-08
申请号：US12738047
申请日：2008-09-29
申请人： Steven M. Goetz
发明人： Steven M. Goetz
IPC分类号： A61B5/00 , A61B5/11 , G06F19/00
CPC分类号： A61B5/0031 , A61B5/0022 , A61B5/11 , A61B2560/0223 , A61B2560/0271 , A61B2562/0219 , G06F19/3418
摘要： Techniques for remotely calibrating an implanted patient sensor with a remote networking device are described. In some embodiments, the sensor is a component of an implantable medical device (IMD). The remote networking device communicates with the IMD via a network to which the IMD and/or external programmer is connected. The IMD may transmit sensor information to the remote networking device when the IMD detects a problem with the sensor or when the patient indicates that therapy is not correctly selected for different activities. New calibration settings may be remotely generated by directly interrogating the sensor and/or communicating with the patient in order to associate sensor output with patient activities, motions, or postures.

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