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91. 发明授权

US07678061B2 System and method for characterizing patient respiration 有权
标题翻译：用于表征患者呼吸的系统和方法
公开(公告)号：US07678061B2
公开(公告)日：2010-03-16
申请号：US10824941
申请日：2004-04-15
申请人： Kent Lee , Quan Ni , Jesse W. Hartley , John D. Hatlestad , Jeffrey E. Stahmann
发明人： Kent Lee , Quan Ni , Jesse W. Hartley , John D. Hatlestad , Jeffrey E. Stahmann
IPC分类号： A61B5/08 , A61N1/00
CPC分类号： A61B5/4806 , A61B5/0205 , A61B5/08 , A61B5/082 , A61N1/08
摘要： Patient respiration may be characterized using a marked respiration waveform involving a respiration waveform annotated with symbols, markers or other indicators representing one or more respiration characteristics. A respiration waveform may be acquired by sensing a physiological parameter modulated by respiration. A marked respiration waveform may be generated based on the acquired respiration waveform and one or more detected respiration waveform characteristics and/or respiration-related conditions. One or more components used to generate the marked respiratory waveform may be fully or partially implantable.
摘要翻译：患者呼吸可以使用标示的呼吸波形来表征，该呼吸波形涉及用符号，标记或代表一个或多个呼吸特征的其它指示符注释的呼吸波形。可以通过感测由呼吸调制的生理参数来获取呼吸波形。可以基于所获取的呼吸波形和一个或多个检测到的呼吸波形特征和/或呼吸相关条件来生成标记的呼吸波形。用于产生标记的呼吸波形的一个或多个组件可以是完全或部分可植入的。

92. 发明申请

US20090292332A1 METHOD AND APPARATUS FOR MORPHOLOGY-BASED ARRHYTHMIA CLASSIFICATION USING CARDIAC AND OTHER PHYSIOLOGICAL SIGNALS 有权
标题翻译：使用心脏和其他生理信号进行形态学基于ARRHYTHMIA分类的方法和装置
公开(公告)号：US20090292332A1
公开(公告)日：2009-11-26
申请号：US12536828
申请日：2009-08-06
申请人： Dan Li , Shelley Cazares , Jaeho Kim , Kent Lee
发明人： Dan Li , Shelley Cazares , Jaeho Kim , Kent Lee
IPC分类号： A61N1/39 , A61B5/02 , A61B5/0205
CPC分类号： A61B5/0464 , A61B5/7264 , A61N1/3621 , A61N1/36521 , A61N1/36542 , A61N1/36564 , A61N1/36571 , A61N1/36578 , A61N1/36585 , A61N1/3925 , A61N1/3962
摘要： A tachyarrhythmia detection and classification system classifies tachyarrhythmias based on an analysis of morphological features of a cardiac signal enhanced by using one or more physiological parameters indicative of hemodynamic stability and/or activity level. The tachyarrhythmia detection and classification system computes a measure of similarity between an arrhythmic waveform of the cardiac signal a template waveform for that cardiac signal, such as a correlation coefficient representative of the correlation between morphological features of the arrhythmic waveform and morphological features of the template waveform. A detected tachyarrhythmia episode is classified by comparing the measure of similarity to a threshold that is dynamically adjusted using the one or more physiological parameters.
摘要翻译：快速心律失常检测和分类系统基于通过使用指示血液动力学稳定性和/或活动水平的一个或多个生理参数来增强的心脏信号的形态学特征的分析来分类快速性心律失常。快速心律失常检测和分类系统计算心脏信号的心律失常波形与该心脏信号的模板波形之间的相似性的度量，例如表示心律失常波形的形态特征与模板波形的形态特征之间的相关性的相关系数。通过将相似性测量值与使用一个或多个生理参数动态调整的阈值进行比较来分类检测到的快速性心律失常发作。

93. 发明授权

US07610094B2 Synergistic use of medical devices for detecting medical disorders 失效
标题翻译：协同使用医疗器械检测医疗障碍
公开(公告)号：US07610094B2
公开(公告)日：2009-10-27
申请号：US10939586
申请日：2004-09-13
申请人： Jeffrey E. Stahmann , Jesse W. Hartley , Kent Lee , Quan Ni
发明人： Jeffrey E. Stahmann , Jesse W. Hartley , Kent Lee , Quan Ni
IPC分类号： A61N1/08 , A61B5/08
CPC分类号： A61B5/1116 , A61B5/0031 , A61B5/02055 , A61B5/0215 , A61B5/02405 , A61B5/0421 , A61B5/0422 , A61B5/0464 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/053 , A61B5/0809 , A61B5/0836 , A61B5/087 , A61B5/103 , A61B5/113 , A61B5/4818 , A61B5/686 , A61B5/7275 , A61B2560/0468 , A61B2562/0219 , A61M16/0051 , A61M16/026 , A61M16/10 , A61M2016/0021 , A61M2016/0039 , A61M2016/0042 , A61M2205/3561 , A61M2205/3592 , A61M2230/04 , A61M2230/10 , A61M2230/432 , A61M2230/435 , A61M2230/60 , A61M2230/63 , A61M2230/65 , A61N1/362 , A61N1/3627 , A61N1/36514 , A61N1/36535 , A61N1/36578 , A61N1/36592 , A61N1/37 , G06F19/00
摘要： Methods and systems for detecting medical disorders through synergistic use of one or more medical devices are described. One or more medical devices are selected to sense one or more physiological parameters associated with a medical disorder. A presence of the medical disorder is assessed based on the sensed parameters. The medical devices used for sensing may be selected from a plurality of patient internal and/or patient-external medical devices.
摘要翻译：描述了通过协同使用一种或多种医疗装置来检测医学病症的方法和系统。选择一个或多个医疗装置来感测与医学病症相关联的一个或多个生理参数。基于所感测的参数来评估医学疾病的存在。用于感测的医疗设备可以从多个患者内部和/或患者外部医疗设备中选择。

94. 发明申请

US20090105778A1 Cardiac Waveform Template Creation, Maintenance and Use 有权
标题翻译：心脏波形模板创建，维护和使用
公开(公告)号：US20090105778A1
公开(公告)日：2009-04-23
申请号：US12341558
申请日：2008-12-22
申请人： Kent Lee , Rob Sweeney
发明人： Kent Lee , Rob Sweeney
IPC分类号： A61N1/00
CPC分类号： A61B5/04525 , A61B5/7264
摘要： The present disclosure describes methods and systems for creating, adjusting, and using cardiac waveform morphology templates. The morphology templates include target regions associated with features of cardiac waveforms. The target regions may be adjusted based on relationships between the target regions and features of detected cardiac waveforms associated with the target regions. The templates may be used to analyze cardiac waveforms to classify or monitor various waveform morphologies. Templates may be created or eliminated based on a frequency of use. According to one approach, template creation involves providing target regions defined by one or more characteristics. The target regions are adjusted based on detected cardiac waveform features having similar characteristics. A template may be created using the target regions adjusted by this process.
摘要翻译：本公开描述了用于创建，调整和使用心脏波形形态学模板的方法和系统。形态学模板包括与心脏波形特征相关的目标区域。可以基于目标区域与与目标区域相关联的检测到的心脏波形的特征之间的关系来调整目标区域。模板可用于分析心脏波形以分类或监测各种波形形态。可以根据使用频率创建或删除模板。根据一种方法，模板创建涉及提供由一个或多个特征定义的目标区域。基于检测到的具有相似特征的心脏波形特征来调整目标区域。可以使用由此过程调整的目标区域来创建模板。

95. 发明申请

US20080256311A1 SNAPSHOT PRESERVED DATA CLONING 有权
标题翻译： SNAPSHOT保存数据克隆
公开(公告)号：US20080256311A1
公开(公告)日：2008-10-16
申请号：US11734081
申请日：2007-04-11
申请人： Kent Lee
发明人： Kent Lee
IPC分类号： G06F13/28
CPC分类号： G06F11/1446 , G06F3/0605 , G06F3/0617 , G06F3/065 , G06F3/067 , G06F11/2007 , G06F11/2089 , G06F2201/84
摘要： A method and device for cloning snapshots is provided. A new snapshot can be created by cloning an existing snapshot. The clone snapshot may use the preserved data of the existing snapshot, thereby obviating the need to copy the preserved data. Additionally, the clone snapshot may be created with a data structure for storing write data. Since the clone snapshot initially has no write data to store, the creation of the entire clone snapshot can be accomplished without copying any preserved data or write data from the existing snapshot, thereby increasing the efficiency with which a clone snapshot can be created.
摘要翻译：提供了克隆快照的方法和设备。可以通过克隆现有快照来创建新的快照。克隆快照可以使用现有快照的保留数据，从而避免复制保留数据的需要。另外，克隆快照可以用用于存储写入数据的数据结构来创建。由于克隆快照最初没有存储的写入数据，因此可以在不复制任何保留的数据或从现有快照写入数据的情况下完成整个克隆快照的创建，从而提高可以创建克隆快照的效率。

96. 发明申请

US20080221468A1 Prediction of disordered breathing 有权
公开(公告)号：US20080221468A1
公开(公告)日：2008-09-11
申请号：US12152029
申请日：2008-05-12
申请人： Jeffrey E. Stahmann , John D. Hatlestad , Quan Ni , Jesse Hartley , Douglas R. Daum , Kent Lee
发明人： Jeffrey E. Stahmann , John D. Hatlestad , Quan Ni , Jesse Hartley , Douglas R. Daum , Kent Lee
IPC分类号： A61B5/08 , A61B5/053
CPC分类号： A61B5/02405 , A61B5/0031 , A61B5/08 , A61B5/0816 , A61B5/1116 , A61B5/1118 , A61B5/4812 , A61B5/4815 , A61B5/4818 , A61B2560/0242 , A61B2562/0219 , A61N1/362 , A61N1/36514
摘要： An approach for predicting disordered breathing involves detecting one or more conditions associated with disordered breathing. The detected conditions are compared to disordered breathing prediction criteria. A prediction of disordered breathing is performed based on the comparison of the detected conditions to the prediction criteria. At least one of comparing the detected conditions to the prediction criteria and predicting disordered breathing is performed at least in part implantably.

97. 发明申请

US20080177954A1 METHOD AND APPARATUS FOR QUICKLY ACCESSING BACKING STORE METADATA 有权
标题翻译：快速访问后备存储元数据的方法和装置
公开(公告)号：US20080177954A1
公开(公告)日：2008-07-24
申请号：US11624524
申请日：2007-01-18
申请人： Kent Lee
发明人： Kent Lee
IPC分类号： G06F12/00
CPC分类号： G06F12/126 , G06F11/1666 , G06F11/2056 , G06F11/2089 , G06F12/0804 , G06F12/0866 , G06F2212/466
摘要： A method, device, and system are provided for accessing metadata in a data storage system. More specifically, a requesting application requests a cache application to allocate a cache page to retrieve metadata from a storage device. After metadata is written to the cache page, the cache page is locked by the requesting application. The cache page is maintained in a locked state by the requesting application. This allows the data stored within the cache page to be quickly accessed and updated by the requesting application without waiting for the cache page to be written back to the storage device after every update to the cache page occurs.
摘要翻译：提供了一种用于访问数据存储系统中的元数据的方法，设备和系统。更具体地，请求应用请求高速缓存应用分配高速缓存页面以从存储设备检索元数据。元数据写入缓存页后，缓存页被请求应用程序锁定。缓存页面由请求应用程序保持在锁定状态。这允许存储在高速缓存页面内的数据被请求应用程序快速访问和更新，而不必在每次更新到高速缓存页面之后等待缓存页面被写回到存储设备。

98. 发明授权

US07336996B2 Rate regularization of cardiac pacing for disordered breathing therapy 有权
标题翻译：评估无序呼吸治疗心脏起搏的正常化
公开(公告)号：US07336996B2
公开(公告)日：2008-02-26
申请号：US10798794
申请日：2004-03-11
申请人： Jesse W. Hartley , Kent Lee , Jeffrey E. Stahmann , Quan Ni
发明人： Jesse W. Hartley , Kent Lee , Jeffrey E. Stahmann , Quan Ni
IPC分类号： A61N1/00
CPC分类号： A61N1/365 , A61B5/0205 , A61B5/02405 , A61N1/3601 , A61N1/36521
摘要： An approach to providing disordered breathing therapy includes providing cardiac overdrive pacing using rate regularization. Overdrive pacing therapy may be initiated following detection or prediction of disordered breathing. Characteristics of the disordered breathing or other patient conditions may be used to modify the pacing therapy.
摘要翻译：提供无序呼吸治疗的方法包括使用速率正规化提供心脏超速起搏。检测或预测无序呼吸后可开始过度起搏治疗。无序呼吸或其他病人状况的特征可用于修改起搏治疗。

99. 发明授权

US07329226B1 System and method for assessing pulmonary performance through transthoracic impedance monitoring 有权
标题翻译：通过经胸阻抗监测评估肺功能的系统和方法
公开(公告)号：US07329226B1
公开(公告)日：2008-02-12
申请号：US10885145
申请日：2004-07-06
申请人： Quan Ni , Jesse W. Hartley , Kent Lee , Jeffrey E. Stahmann
发明人： Quan Ni , Jesse W. Hartley , Kent Lee , Jeffrey E. Stahmann
IPC分类号： A61N1/39 , A61N1/00 , A61B5/08 , A61B5/05
CPC分类号： A61B5/0809 , A61B5/0002 , A61B5/0535 , A61N1/36521 , G06F19/3418
摘要： A system and method for assessing pulmonary performance through transthoracic impedance monitoring is described. Transthoracic impedance measures are directly collected through an implantable medical device. The transthoracic impedance measures are correlated to pulmonary functional measures relative to performance of at least one respiration cycle. The transthoracic impedance measures are grouped into at least one measures set corresponding to one of an inspiratory phase and an expiratory phase. The at least one transthoracic impedance measures set are evaluated to identify a respiratory pattern relative to the inspiratory phase or the expiratory phase to represent pulmonary performance.
摘要翻译：描述了通过经胸阻抗监测来评估肺功能的系统和方法。通过可植入的医疗设备直接收集胸廓阻抗测量。经胸廓阻抗测量与相对于至少一个呼吸周期的性能的肺功能测量相关。经胸阻抗测量被分组成对应于吸气相和呼气阶段之一的至少一个测量组。评估至少一个经胸廓阻抗测量集合以鉴定相对于吸气相或呼气阶段的呼吸模式以表示肺功能。

100. 发明申请

US20070282215A1 Detection of disordered breathing 有权
标题翻译：检测无序呼吸
公开(公告)号：US20070282215A1
公开(公告)日：2007-12-06
申请号：US11890404
申请日：2007-08-06
申请人： Quan Ni , John Hatlestad , Jesse Hartley , Jeff Stahmann , Jaeho Kim , Kent Lee
发明人： Quan Ni , John Hatlestad , Jesse Hartley , Jeff Stahmann , Jaeho Kim , Kent Lee
IPC分类号： A61B5/02
CPC分类号： A61B5/4818 , A61B5/0205 , A61B5/4806 , A61B5/4809 , A61B5/7264
摘要： Devices and methods for detecting disordered breathing involve determining that the patient is asleep and sensing one or more signals associated with disordered breathing indicative of sleep-disordered breathing while the patient is asleep. Sleep-disordered breathing is detected using the sensed signals associated with disordered breathing. The sensed signals associated with disordered breathing may also be used to acquire a respiration pattern of one or more respiration cycles. Characteristics of the respiration pattern are determined. The respiration pattern is classified as a disordered breathing episode based on the characteristics of the respiration pattern. One or more processes involved in the detection of disordered breathing are performed using an implantable device.
摘要翻译：用于检测无序呼吸的装置和方法涉及确定患者睡着并且感测与患者睡着时指示睡眠呼吸紊乱的无序呼吸相关联的一个或多个信号。使用与无序呼吸相关的感测信号来检测睡眠呼吸障碍。与无序呼吸相关联的感测信号也可用于获取一个或多个呼吸循环的呼吸模式。确定呼吸模式的特征。根据呼吸模式的特点，呼吸模式被分类为无序呼吸发作。使用可植入装置进行涉及无序呼吸检测的一个或多个过程。

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