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1. 发明申请

US20210104673A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME 有权
公开(公告)号：US20210104673A1
公开(公告)日：2021-04-08
申请号：US17117412
申请日：2020-12-10
申请人： SAMSUNG DISPLAY CO., LTD.
发明人： MIEUN JUN , JONGWOO KIM , YOUNGKOOK KIM , SEOKHWAN HWANG
IPC分类号： H01L51/00 , C07C211/54 , C07F7/08 , H01L51/50 , C07D209/82 , C07F5/02 , C07D313/06
摘要： Provided are a condensed cyclic compound and an organic light-emitting device including the same. The organic light-emitting device may include a first electrode, a second electrode, and an organic layer disposed between the first electrode and the second electrode. The organic layer may include the condensed cyclic compound represented by Formula 1: In Formula 1, rings A1, A2, and A3 may each be independently a C5-C60 carbocyclic group or a C2-C30 heterocyclic group, and n1 to n3 may each be independently 0 or 1, provided that the sum of n1, n2, and n3 is 1. In addition, the descriptions of X1, L1 to L9, a1 to a9, Ar1 to Ar6, b1 to b6, R1 to R3, and c1 to c3 are as defined in the present specification.

2. 发明授权

US10431751B2 Compound and organic electronic device comprising the same 有权
公开(公告)号：US10431751B2
公开(公告)日：2019-10-01
申请号：US15416507
申请日：2017-01-26
申请人： Nichem Fine Technology Co., Ltd.
发明人： Liang-Di Liao , Shwu-Ju Shieh , Chi-Chung Chen
IPC分类号： H01L51/50 , H01L51/00 , C07F15/00 , C09K11/06 , C07C255/51 , C07D213/06 , C07D213/22 , C07D213/57 , C07D235/18 , C07D239/26 , C07D239/74 , C07D251/24 , C07C211/61 , C07D223/14 , C07D307/91 , C07D313/06 , C07D213/38 , H01L51/42
摘要： A novel compound is disclosed, which is represented by the following Formula (I): wherein Ar1, Ar2, Ar3, Ar4, L, Q, G, n1, n2, m1, m2 and q represent the same as defined in the specification. In addition, an organic electronic device is also disclosed, and an organic layer therein comprises the novel compound of the present invention.

3. 发明授权

US10374170B2 Substituted oxepines 有权
公开(公告)号：US10374170B2
公开(公告)日：2019-08-06
申请号：US15101219
申请日：2014-11-18
申请人： Merck Patent GmbH
发明人： Amir Hossain Parham , Arne Buesing , Philipp Stoessel , Anja Gerhard , Christof Pflumm , Thomas Eberle , Anja Jatsch , Jonas Valentin Kroeber , Lars Dobelmann-Mara
IPC分类号： H01L51/00 , C07D313/06 , C07D405/10 , A61N5/06 , C07D405/04 , C07D405/14 , C07D407/04 , C07D407/10 , C07D407/12 , C07D407/14 , C07D487/04 , C07D491/044 , C09K11/02 , C09K11/06 , H01L51/50 , A61N5/067
摘要： The invention relates to materials, to electroluminescence devices comprising said materials and to the use thereof.

4. 发明授权

US10112919B2 Methods of preparing oxa-bicycloalkene 有权
公开(公告)号：US10112919B2
公开(公告)日：2018-10-30
申请号：US15838455
申请日：2017-12-12
申请人： INTERNATIONAL FLAVORS & FRAGRANCES INC.
发明人： Avelino Corma Canós , Antonio Leyva-Pérez , Estela Espinós Ferri , Carlos López Cruz
IPC分类号： C07D311/94 , C11B9/00 , B01J23/34 , C07B33/00 , C07B37/10 , C07D313/06
摘要： Disclosed is a method of preparing an oxa-bicycloalkene via the reaction of a cycloalkanone and an allyl alcohol compound in the presence of an organic acid, a manganese catalyst, and oxygen at a predetermined temperature.

5. 发明授权

US10081592B2 Complex and structurally diverse compounds 有权
公开(公告)号：US10081592B2
公开(公告)日：2018-09-25
申请号：US14387028
申请日：2013-03-25
申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS , Paul J. Hergenrother , Robert W. Huigens, III , Karen C. Morrison , Robert W. Hicklin, II , Timothy A. Flood, Jr.
发明人： Paul J. Hergenrother , Robert W. Huigens, III , Karen C. Morrison , Robert W. Hicklin, II , Timothy A. Flood, Jr.
IPC分类号： C07D401/14 , C07C69/757 , C07D311/94 , C07D313/06 , C07D223/14 , C07D401/04 , C07D471/04 , C07D471/08 , C07D493/08 , C07D513/04 , C07D519/00 , C07D303/10 , C07C59/205 , C07C62/32 , C07C62/38 , C07B37/06 , C07B37/08 , C07D307/93 , C07D313/08 , C07D405/06 , C07D405/12 , C07D413/06 , C07J21/00 , C07J69/00 , C07J71/00 , C07J73/00 , C07J75/00
CPC分类号： C07C69/757 , C07B37/06 , C07B37/08 , C07C59/205 , C07C62/32 , C07C62/38 , C07C2601/16 , C07C2602/44 , C07C2603/86 , C07D223/14 , C07D303/10 , C07D307/93 , C07D311/94 , C07D313/06 , C07D313/08 , C07D401/04 , C07D401/14 , C07D405/06 , C07D405/12 , C07D413/06 , C07D471/04 , C07D471/08 , C07D493/08 , C07D513/04 , C07D519/00 , C07J21/008 , C07J69/00 , C07J71/001 , C07J71/0031 , C07J73/005 , C07J73/008 , C07J75/005
摘要： The invention a novel, general, and facile strategy for the creation of small molecules with high structural and stereochemical complexity. Aspects of the methods include ring system distortion reactions that are systematically applied to rapidly convert readily available natural products to structurally complex compounds with diverse molecular architectures. Through evaluation of chemical properties including fraction of sp3 carbons, ClogP, and the number of stereogenic centers, these compounds are shown to be significantly more complex and diverse than those in standard screening collections. This approach is demonstrated with natural products (gibberellic acid, adrenosterone, and quinine) from three different structural classes, and methods are described for the application of this strategy to any suitable natural product.

7. 发明授权

US09388157B2 Bicyclic compound and use thereof for medical purposes 有权
公开(公告)号：US09388157B2
公开(公告)日：2016-07-12
申请号：US14587829
申请日：2014-12-31
申请人： ONO PHARMACEUTICAL CO., LTD.
发明人： Tohru Kambe , Toru Maruyama , Shinsaku Yamane , Satoshi Nakayama , Kousuke Tani
IPC分类号： C07D313/00 , C07D313/06 , A61K31/4427 , A61K31/558 , C07D401/06 , C07D417/04 , C07D407/12 , C07D405/06
CPC分类号： A61K31/335 , A61K9/0048 , A61K31/4427 , A61K31/558 , C07D313/06 , C07D401/06 , C07D405/06 , C07D407/12 , C07D417/04
摘要： Since a compound represented by the general formula (I) (wherein definition of each group is as described in the specification), a salt thereof, a solvate thereof, or a prodrug thereof has strong and sustaining intraocular pressure lowering activity and, further, has no side effect on eyes such as ocular stimulating property (hyperemia, corneal clouding etc.), aqueous humor protein rise etc., it has high safety, and can be an excellent agent for preventing and/or treating glaucoma etc.

8. 发明申请

US20110039922A1 18beta-GLYCYRRHETINIC ACID DERIVATIVES AND SYNTHETIC METHOD THEREOF 有权
标题翻译： 18beta-GLYCYRRHETINIC酸衍生物及其合成方法
公开(公告)号：US20110039922A1
公开(公告)日：2011-02-17
申请号：US12649437
申请日：2009-12-30
申请人： Chun-Nan Lin , Dravidum Maitraie , Jih-Pyang Wang , Chi-Feng Hung , Huang-Yao Tu , Ya-Ting Liou , Bai-Luh Wei , Shyh-Chyun Yang
发明人： Chun-Nan Lin , Dravidum Maitraie , Jih-Pyang Wang , Chi-Feng Hung , Huang-Yao Tu , Ya-Ting Liou , Bai-Luh Wei , Shyh-Chyun Yang
IPC分类号： A61K31/335 , C07D313/06 , C07C69/74 , C07C61/16 , A61K31/215 , A61K31/19 , A61P29/00
CPC分类号： C07D313/06 , A61K31/19 , A61K31/215 , A61K31/335 , C07C231/02 , C07C231/12 , C07D313/08 , C07J63/008 , C07J73/003
摘要： The present invention provides a chemical compound having the structure being one selected from a group consisting of wherein R1 is one selected from a group consisting of COOCH3, COOCH2Ph, CONHCH(CH3)2 and CONHC6H5, R2 is one selected from a group consisting of H, CH3 and CH(CH3)2, R3 is one selected from a group consisting of H, CH3, CH(CH3)2 and CH2Ph, and R4 is one of CH(CH3)2 and C6H5.
摘要翻译：本发明提供一种具有以下结构的化合物：其中R 1为选自COOCH 3，COOCH 2 Ph，CONHCH（CH 3）2和CONHC 6 H 5中的一个，R 2为选自H ，CH 3和CH（CH 3）2，R 3是选自H，CH 3，CH（CH 3）2和CH 2 Ph的一个，R 4是CH（CH 3）2和C 6 H 5之一。

9. 发明申请

US20100041745A1 Aigialomycin D and Derivatives Thereof and Their Use in Treating Cancer or Malaria or a Microbial Infection 审中-公开
标题翻译： Aigialomycin D及其衍生物及其在治疗癌症或疟疾或微生物感染中的应用
公开(公告)号：US20100041745A1
公开(公告)日：2010-02-18
申请号：US12374610
申请日：2007-07-20
申请人： Anqi Chen , Quang Vu Nguyen
发明人： Anqi Chen , Quang Vu Nguyen
IPC分类号： A61K31/335 , C07D313/06 , A61P35/00 , A61P33/06 , A61P31/00
CPC分类号： C07D313/06 , A61K31/335 , C07D493/04 , C07D493/14 , C07D493/22 , Y02A50/411
摘要： The invention describes a process for making compound (2), comprising the step of cyclising diene (3). Compound (2) may be aigialomycin D or a derivative thereof or may be elaborated to make aigialomycin D or derivative thereof. Furthermore compound (2) or derivative thereof can be used in treating cancer or malaria or a microbial infection.
摘要翻译：本发明描述了一种制备化合物（2）的方法，包括使二烯（3）环化的步骤。化合物（2）可以是aigialomycin D或其衍生物，或者可以精制来制备aigialomycin D或其衍生物。此外，化合物（2）或其衍生物可用于治疗癌症或疟疾或微生物感染。

10. 发明申请

US20090299081A1 Asymmetric Synthesis of Rocaglamides via Enantioselective Photocycloaddition Mediated by Chiral Bronsted Acids 有权
标题翻译：通过手性布朗斯台德酸介导的对映选择性光环加成反应的罗卡胶的非对称合成
公开(公告)号：US20090299081A1
公开(公告)日：2009-12-03
申请号：US12301727
申请日：2007-05-21
申请人： John A. Porco, JR. , Baudouin Gerard
发明人： John A. Porco, JR. , Baudouin Gerard
IPC分类号： C07D307/77 , C07D313/06
CPC分类号： C07D317/12 , C07D307/93 , C07D317/72 , C07D493/08 , C07D493/10
摘要： The present invention provides a new strategies for the synthesis of compounds of the rocaglamide family and related natural products. The synthetic approach generally involves photochemical generation of an oxidopyrylium species from a 3-hydroxychromone derivative followed by an enantioselective 1,3-dipolar cycloaddition of the oxidopyrylium species to a dipolarophile in the presence of a TADDOL derivative. This approach can be used for the formation of adducts containing an aglain core structure. Methods of the conversion of aglain core structures to aglain, rocaglamide and forbaglin ring systems are also provided. The present invention also relates to the use of rocaglamide/aglain/forbaglin derivatives for the manufacture of medicaments for use in the treatment of cancer or cancerous conditions, disorders associated with cellular hyperproliferation, or NF-κB-dependent conditions.
摘要翻译：本发明提供了合成罗卡酰胺家族化合物和相关天然产物的新策略。合成方法通常涉及在3-羟基色酮衍生物中光化学生成氧化吡啶鎓物质，随后在TADDOL衍生物存在下，将氧化吡啶类物质的对映选择性1,3-偶极环加成到偶极嗜酸细胞。该方法可用于形成含有阿格林核心结构的加合物。还提供了将阿格林核心结构转化为阿格林，罗卡酰胺和巴格林环系统的方法。本发明还涉及用于制造用于治疗癌症或癌症病症的药物，与细胞过度增殖相关的疾病或NF-κB依赖性病症的药物的罗卡酰胺/阿格林/用于囊霉素衍生物的用途。

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