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1. 发明授权

US10948222B2 Hybrid thermal apparatus 有权
公开(公告)号：US10948222B2
公开(公告)日：2021-03-16
申请号：US16346235
申请日：2017-11-02
申请人： UNIVERZA V LJUBLJANI
发明人： Andrej Zerovnik , Jaka Tusek
IPC分类号： F25B23/00 , F25B25/00 , F25B21/00
摘要： The present invention refers to a hybrid thermal apparatus comprising at least one heat exchanger and at least one heat source and/or heat sink. The thermal apparatus according to the invention is formed as a combination of a first thermal apparatus (1, 15) based on a vapour-compression principle and comprising a first medium for heat transfer, and of a second thermal apparatus (2, 16) based on an elastocaloric principle and comprising a second medium for heat transfer. Said thermal apparatuses (1, 15; 2, 16) have at least one deformable heat exchanger (3, 21) of elastocaloric material in common.

2. 发明授权

US08875385B2 Apparatus for retaining a package of laminations of an electromagnetic core in a device for the production thereof 有权
标题翻译：用于将电磁铁芯的叠片保持在用于制造电磁铁芯的装置中的装置
公开(公告)号：US08875385B2
公开(公告)日：2014-11-04
申请号：US13504218
申请日：2009-10-28
申请人： Marko Hladnik , Niko Herakovic
发明人： Marko Hladnik , Niko Herakovic
IPC分类号： H02K15/00 , H01F41/02 , B21D28/22 , B21D45/00 , H02K15/02
CPC分类号： H01F41/0233 , B21D28/22 , B21D45/003 , H02K15/02 , Y10T29/53143 , Y10T29/5317 , Y10T29/53174
摘要： An apparatus for retaining a package of laminations of an electromagnetic core in a device (3) for the production thereof that is mounted into a panel (1) arranged at a distance from a yoke (2) of said device (3) for the production of individual laminations (4) and mutual joining of same into a package (5), wherein it comprises peripheral units like an aggregate for pressurized hydraulic oil, sensors, control unit and ejector. The apparatus of the invention is formed in a way that within said panel (1) a cylinder (7) is arranged co-axially with a sleeve (6) within said yoke (2), said cylinder (7) housing a hydraulic piston (8) with a piston rod (9) with a coaxial drilled hole (12), wherein on the top of said piston (8) adjacent to said sleeve (6) there is a pivotally mounted panel (10) that is simultaneously supported on said piston (8) by a spring (11) and said piston rod (9) is further led within said cylinder (7) at a distance by means of three mutually distant gaskets (14) in order to create two spaces (15) and (16) between said piston rod (9) and said cylinder (7) in that a central section (9a) of said piston rod (9) is thinner and that both spaces (15) and (16) are provided with hydraulic connections (17) and (18) for an alternate supply of pressurized oil into one or another space (15) and (16).
摘要翻译：一种用于将电磁芯的叠片保持在用于制造其的装置（3）中的装置，其被安装在布置成距所述装置（3）的轭（2）一定距离的面板（1）中用于生产的单独叠片（4）并将其相互连接到包装（5）中，其中它包括外围单元，例如用于加压液压油的集料，传感器，控制单元和喷射器。本发明的装置形成为在所述面板（1）内形成一个圆柱体（7）与所述磁轭（2）内的套管（6）同轴设置，所述气缸（7）容纳液压活塞 8）具有同轴钻孔（12）的活塞杆（9），其中在所述活塞（8）的与所述套筒（6）相邻的顶部上具有枢转安装的面板（10），其同时支撑在所述活塞（8）通过弹簧（11）和所述活塞杆（9）进一步通过三个彼此间隔的垫圈（14）在所述气缸（7）内一定距离地引导，以便产生两个空间（15）和（在所述活塞杆（9）和所述气缸（7）之间，所述活塞杆（9）的中心部分（9a）更薄，并且两个空间（15）和（16）都设有液压连接件）和（18）用于将压力油替代供应到一个或另一个空间（15）和（16）中。

3. 发明授权

US5824652A Heterocyclic acyldipeptides, processes for the preparation thereof and pharmaceutical compositions containing the same 失效
标题翻译：杂环酰基二肽，其制备方法和含有它们的药物组合物
公开(公告)号：US5824652A
公开(公告)日：1998-10-20
申请号：US537782
申请日：1996-01-04
申请人： Danijel Kikelj , Elizabeta Suhadolc , Alenka Rutar , Slavko Pecar , Alesa Puncuh , Uros Urleb , Vesna Leskovsek , Gasper Marc , Marija Sollner , Ales Krbavcic , Gregor Sersa , Srdjan Novakovic , Lucka Povsic , Anton Stalc
发明人： Danijel Kikelj , Elizabeta Suhadolc , Alenka Rutar , Slavko Pecar , Alesa Puncuh , Uros Urleb , Vesna Leskovsek , Gasper Marc , Marija Sollner , Ales Krbavcic , Gregor Sersa , Srdjan Novakovic , Lucka Povsic , Anton Stalc
IPC分类号： A61K38/00 , A61P35/00 , A61P37/04 , C07D265/36 , C07D279/16 , C07K5/06 , C07K5/062 , C07D471/02
CPC分类号： C07K5/06026 , C07D265/36 , C07D279/16 , A61K38/00
摘要： Heterocyclic acyldipeptides of the formula I ##STR1## wherein Z represents an oxygen or sulphur atom or a --CH.sub.2 -group; R.sub.1, R.sub.2 and R.sub.3 individually represent hydrogen or certain organic groups; R.sub.4 and R.sub.5, which are identical or different, represent an OR.sub.6 or NHR.sub.6 group, wherein R.sub.6 is hydrogen or certain organic groups; Y represents a --CH.sub.2 --, .dbd.CH-- or .dbd.N-- group; A represents a --(CH.sub.2).sub.3 -- group when Y is --CH.sub.2 --, the two rings being transcondensed, or a ##STR2## wherein R.sub.7 represents H, F, Br, Cl, nitro, or certain organic groups when Y is .dbd.CH-- or .dbd.N--; and their pharmaceutically acceptable salts are provided. These heterocyclic acyldipeptides and their salts are useful as active compounds in medicaments having immunostimulatory and antitumor activity.
摘要翻译： PCT No.PCT / SI94 / 00003 Sec。 371日期1996年1月4日 102（e）日期1996年1月4日PCT 1994年4月21日PCT PCT。公开号WO94 / 24152 日期：1994年10月27日式I硫原子或-CH 2 - 基团的杂环酰基二肽; R1，R2和R3各自表示氢或某些有机基团; R4和R5相同或不同，表示OR6或NHR6基团，其中R6是氢或某些有机基团; Y表示-CH 2 - ，= CH-或= N-基; 当Y是-CH 2 - 时，A表示 - （CH 2）3 - 基团，该两个环是被缩聚的，或者当Y是= CH时，其中R 7表示H，F，Br，Cl，硝基或某些有机基团 - 或= N- 并提供其药学上可接受的盐。这些杂环酰基二肽及其盐可用作具有免疫刺激和抗肿瘤活性的药物中的活性化合物。

4. 发明授权

US11835583B1 Computer-implemented method for diagnosing states of a battery 有权
公开(公告)号：US11835583B1
公开(公告)日：2023-12-05
申请号：US17829968
申请日：2022-06-01
申请人： Univerza V Ljubljani
发明人： Toma{hacek over (z)} Katra{hacek over (s)}nik , Klemen Zelic , Amer Amor Chowdhury Haque , Ivo Pacnik , Igor Mele , Andra{hacek over (z)} Kravos
IPC分类号： G01R31/367 , G06F30/27 , G01R31/392 , H02J7/00 , G01R31/382
CPC分类号： G01R31/367 , G01R31/382 , G01R31/392 , G06F30/27 , H02J7/005 , H02J7/0048
摘要： A computer-implemented method of diagnosing one or more SoXs, such as State-of-Charge (SoC), State-of-Health (SoH), State-of-Energy (SoE), State-of-Power (SoP), State-of-Function (SoF) and State-of-Safety (SoS), of at least one battery, comprises a SoX diagnostics loop, which includes a given battery model, and a model update loop, which is configured to update the battery model, the method comprising:

receiving, by the SoX diagnostics loop from at least one sensor, at least one measured battery parameter of the battery,
determining, by the SoX diagnostics loop, at least one SoX descriptor of the battery using at least one of the following: at least one SoX parameter, at least one comparison of the at least one SoX parameter: to its previous value, to the at least one another SoX parameter, to the at least one threshold value, wherein the at least one SoX parameter is one of the following: the at least one measured battery parameter, at least one simulated battery parameter provided by the battery model, the at least one state variable and at least one model parameter of the battery model,
determining, by the SoX diagnostics loop, at least one SoX value associated with the SoX in dependence on the at least one of the following: SoX descriptor and SoX parameter,
determining, by the SoX diagnostics loop, based on at least one of the following: the at least one SoX parameter, the at least one SoX descriptor and the at least one SoX value, whether an update is to be carried out on the model,
in response to determining that the update is to be carried out, updating, by the model update loop, the battery model, and
providing, by the model update loop, the updated battery model to the SoX diagnostics loop.

5. 发明公开

US20230331674A1 N-((1-BENZYLPIPERIDIN-3-YL)METHYL)-N-(2-METHOXYETHYL)NAPHTHALENE-2-SULFONAMIDE FOR THE TREATMENT OF CANINE COGNITIVE DYSFUNCTION AND OTHER FORMS OF DEMENTIA IN DOGS 审中-公开
公开(公告)号：US20230331674A1
公开(公告)日：2023-10-19
申请号：US18027144
申请日：2021-09-21
申请人： UNIVERZA V LJUBLJANI
发明人： Maja ZakoSek , Sonja Prpar Mihevc , Gregor Majdic , Urban Ko{hacek over (s)}ak , Stanislav Gobec
IPC分类号： C07D211/28 , A61P25/28
CPC分类号： C07D211/28 , A61P25/28
摘要： The present invention relates to the fields of medicinal chemistry and veterinary medicine, and in particular to N-((1-benzylpiperidin-3-yl)methyl)-N-(2-methoxyethyl)naphthalene-2-sulfonamide as a pharmaceutically active compound. The compound of the present invention has been proven for the first time to be particularly useful for the treatment of canine cognitive dysfunction and other forms of dementia in dogs which may be therapeutically modified by altering the activity of butyrylcholinesterase.

6. 发明授权

US11349309B2 Method and device for improved under-frequency load shedding in electrical power systems 有权
公开(公告)号：US11349309B2
公开(公告)日：2022-05-31
申请号：US17046068
申请日：2018-04-09
申请人： UNIVERZA V LJUBLJANI
发明人： Urban Rudez
IPC分类号： H02J3/14 , H02H3/46 , H02H7/26 , H02H3/44 , H02J13/00
摘要： A method and device for load shedding in an electrical power system is provided. The electrical power system includes a device that electrically couples one or more load feeder lines to the electrical power system, where each load feeder lines provides power to consumers. The method includes: monitoring the electrical frequency of the electrical power system and monitoring a frequency stability parameter, which is dependent on a rate of change of the electrical frequency. A control signal is generated to disconnect at least one load feeder line by the device when the monitored frequency is at or below at least a predetermined disconnection frequency threshold and the monitored frequency stability parameter is at or has passed at least one predetermined frequency stability parameter threshold.

7. 发明授权

US09630911B2 Genes for biosynthesis of tetracycline compounds and uses thereof 有权
公开(公告)号：US09630911B2
公开(公告)日：2017-04-25
申请号：US13751251
申请日：2013-01-28
申请人： Univerza v Ljubljani
发明人： Hrvoje Petkovic , Peter Raspor , Urska Lesnik
IPC分类号： C07C237/26 , C07C49/747 , C07C225/20 , C07K14/36
CPC分类号： C07C237/26 , C07C49/747 , C07C225/20 , C07C2603/46 , C07K14/36
摘要： The invention relates to tetracycline products produced by genetically engineered cells, and to therapeutic methods using such tetracyclines. The present invention is based on the cloning and heterologous expression of genes encoding the chelocardin biosynthetic pathway.

8. 发明公开

US20240287540A1 NEW BIO-PESTICIDES FOR CONTROLLING PLANT PESTS 审中-公开
公开(公告)号：US20240287540A1
公开(公告)日：2024-08-29
申请号：US18644512
申请日：2024-04-24
申请人： KMETIJSKI INŠTITUT SLOVENIJE , Univerza v Ljubljani
发明人： Anastasija PANEVSKA , Jaka RAZINGER , Kristina SEPCIC , Peter MACEK , Matej SKOCAJ , Špela MODIC , Maruša NOVAK , Matej BUTALA , Vesna HODNIK , Maja GRUNDNER , Tom TURK
IPC分类号： C12N15/82 , C07K14/37
CPC分类号： C12N15/8286 , C07K14/37
摘要： The present invention relates to cytolytic bi-component protein complexes consisting of a plurality of molecules of a member of the aegerolysin family and a plurality of molecules of a member of the MACPF superfamily, and particularly to their use for controlling a plant pest, such as for controlling Colorado potato beetle (Leptinotarsa decemlineata) or Western corn rootworm (Diabrotica virgifera virgifera). More specifically, the invention relates to transgenic plants forming cytolytic bi-component protein complexes by a plurality of molecules of one of the aegerolysins ostreolysin and pleurotolysin A with a plurality of molecules of pleurotolysin B (PlyB) or similar proteins, which have been transformed into said plants to be toxic for the aforementioned agricultural pest insects.

9. 发明授权

US11480616B2 Computer-implemented method and data processing system for modelling and/or simulating and/or emulating a battery 有权
公开(公告)号：US11480616B2
公开(公告)日：2022-10-25
申请号：US17721625
申请日：2022-04-15
申请人： Univerza V Ljubljani
发明人： Toma{hacek over (z)} Katra{hacek over (s)}nik , Klemen Zelic , Amer Amor Chowdhury Haque , Ivo Pacnik , Igor Mele , Andra{hacek over (z)} Kravos
IPC分类号： G01R31/367 , G06F30/33
摘要： A method for modeling, simulating, or emulating a battery may include generating an equivalent electric circuit model of a battery. The equivalent electric circuit model may include models of the battery's cathode and anode. At least one of the models of the cathode and anode may comprise one or more sub-circuit models. A sub-circuit model may comprise a first current inlet, a second current inlet, at least one voltage source, one or more resistors, and a capacitance. A first current path may be arranged between the first current inlet and the second current inlet. The at least one voltage source and the one or more resistors may be arranged in series in the first current path. A second current path may be arranged in parallel to the first current path between the first current inlet and the second current inlet. The capacitance may be arranged in the second current path.

10. 发明申请

US20210323957A1 NEW CLASS OF DNA GYRASE AND/OR TOPOISOMERASE IV INHIBITORS WITH ACTIVITY AGAINST GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA 有权
公开(公告)号：US20210323957A1
公开(公告)日：2021-10-21
申请号：US17272871
申请日：2019-09-03
申请人： Univerza v Ljubljani , Szegedi Biológiai Kutatóközpont
发明人： Tihomir Tomasic , Nace Zidar , Martina Durcik , Janez Ilas , Anamarija Zega , Cristina Durante Cruz , Päivi Tammela , Csaba Pál , Ákos József Nyerges , Danijel Kikelj , Lucija Peterlin Masic
IPC分类号： C07D417/12 , A61P31/04 , C07D417/14
摘要： The present invention relates to compounds having a structure of general formula (I), processes for their preparation, pharmaceutical compositions containing them as the active ingredient, to their use as medicaments and to their use in the manufacture of medicaments for use in the treatment of bacterial infections in humans and warm-blooded animals.

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