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1. 发明申请

US20110112599A1 MRI SIGNAL FILTERING FOR IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：用于可植入医疗器械的MRI信号滤波
公开(公告)号：US20110112599A1
公开(公告)日：2011-05-12
申请号：US12617532
申请日：2009-11-12
申请人： Zin Zhang , J. Christopher Moulder , George I. Isaac , Gabriel A. Mouchawar , Peter Boileau , Ingmar Viohl
发明人： Zin Zhang , J. Christopher Moulder , George I. Isaac , Gabriel A. Mouchawar , Peter Boileau , Ingmar Viohl
IPC分类号： A61N1/08
CPC分类号： G01R33/288 , A61N1/36521 , A61N1/3718 , A61N1/3754 , G01R33/3685
摘要： A filtering scheme for an implantable medical device mitigates potentially adverse effects that may be caused by MRI-induced signals. In some aspects filtering is provided to attenuate MRI-induced signals on an implanted cardiac lead that is coupled to an implanted device. In some aspects the filter may be configured to complement a capacitor circuit (e.g., a feedthrough capacitor) that reduces the amount of EMI that enters the implanted device via the cardiac lead. In some implementations the filter consists of a LC tank circuit and a series LC circuit, where the LC tank circuit is in series with the cardiac lead and a cardiac stimulation circuit and the series LC circuit is in a shunt configuration across the cardiac stimulation circuit.
摘要翻译：用于可植入医疗装置的过滤方案减轻了可能由MRI诱导的信号引起的潜在的不利影响。在一些方面，提供过滤以减少与植入装置耦合的植入心脏引线上的MRI诱导信号。在一些方面，滤波器可以被配置为补充通过心脏引线减少进入植入装置的EMI量的电容器电路（例如，馈通电容器）。在一些实施方式中，滤波器由LC谐振电路和串联LC电路组成，其中LC谐振电路与心脏引线和心脏刺激电路串联，并且串联LC电路处于穿过心脏刺激电路的分流配置。

2. 发明授权

US08886319B2 MRI signal filtering for implantable medical device 有权
标题翻译：可植入医疗器械的MRI信号滤波
公开(公告)号：US08886319B2
公开(公告)日：2014-11-11
申请号：US12617532
申请日：2009-11-12
申请人： Jin Zhang , J. Christopher Moulder , George I. Isaac , Gabriel A. Mouchawar , Peter Boileau , Ingmar Viohl
发明人： Jin Zhang , J. Christopher Moulder , George I. Isaac , Gabriel A. Mouchawar , Peter Boileau , Ingmar Viohl
IPC分类号： A61N1/08 , G01R33/28 , A61N1/37 , A61N1/375 , A61N1/365 , G01R33/36
CPC分类号： G01R33/288 , A61N1/36521 , A61N1/3718 , A61N1/3754 , G01R33/3685
摘要： A filtering scheme for an implantable medical device mitigates potentially adverse effects that may be caused by MRI-induced signals. In some aspects filtering is provided to attenuate MRI-induced signals on an implanted cardiac lead that is coupled to an implanted device. In some aspects the filter may be configured to complement a capacitor circuit (e.g., a feedthrough capacitor) that reduces the amount of EMI that enters the implanted device via the cardiac lead. In some implementations the filter consists of a LC tank circuit and a series LC circuit, where the LC tank circuit is in series with the cardiac lead and a cardiac stimulation circuit and the series LC circuit is in a shunt configuration across the cardiac stimulation circuit.
摘要翻译：用于可植入医疗装置的过滤方案减轻了可能由MRI诱导的信号引起的潜在的不利影响。在一些方面，提供过滤以减少与植入装置耦合的植入心脏引线上的MRI诱导信号。在一些方面，滤波器可以被配置为补充通过心脏引线减少进入植入装置的EMI量的电容器电路（例如，馈通电容器）。在一些实施方式中，滤波器由LC谐振电路和串联LC电路组成，其中LC谐振电路与心脏引线和心脏刺激电路串联，并且串联LC电路处于穿过心脏刺激电路的分流配置。

3. 发明授权

US07197360B1 Methods and systems for using an inductor to increase capacitor reformation efficiency in an implantable cardiac device (ICD) 有权
标题翻译：使用电感提高可植入式心脏装置（ICD）中的电容器重组效率的方法和系统
公开(公告)号：US07197360B1
公开(公告)日：2007-03-27
申请号：US11035348
申请日：2005-01-12
申请人： J. Christopher Moulder , Joseph Beauvais , George I. Isaac , Gabriel A. Mouchawar
发明人： J. Christopher Moulder , Joseph Beauvais , George I. Isaac , Gabriel A. Mouchawar
IPC分类号： A61N1/00
CPC分类号： A61N1/3956
摘要： Methods and systems for increasing capacitor reformation efficiency in an implantable cardiac device (ICD) are presented. In one embodiment, a method and system provide for: (1) fully charging a first capacitor, (2) transferring energy from the first capacitor to an inductor, (3) transferring energy from the inductor to the second capacitor, and (4) completing charging of the second capacitor. In another embodiment, a method and system provide for: (1) fully charging a first capacitor, (2) sharing energy from the first capacitor with a second capacitor, and (3) completing charging of the second capacitor. In yet another embodiment, a method and system provide for: (1) fully charging a first capacitor, (2) sharing energy from the first capacitor with a second capacitor, (3) transferring remaining energy from the first capacitor to an inductor, (4) transferring energy from the inductor to the second capacitor, and (5) completing charging of the second capacitor.
摘要翻译：提出了用于增加可植入心脏装置（ICD）中的电容器重组效率的方法和系统。在一个实施例中，一种方法和系统提供：（1）完全充电第一电容器，（2）将能量从第一电容器传递到电感器，（3）将能量从电感器传递到第二电容器;以及（4）完成第二电容器的充电。在另一个实施例中，一种方法和系统提供：（1）对第一电容器充分充电，（2）从第一电容器与第二电容器共享能量，以及（3）完成第二电容器的充电。在另一个实施例中，一种方法和系统提供：（1）对第一电容器进行完全充电，（2）从第一电容器与第二电容器共享能量，（3）将剩余能量从第一电容器转移到电感器（ 4）将电能从电感器传递到第二电容器，（5）完成第二电容器的充电。

4. 发明申请

US20110125240A1 BIOCOMPATIBLE INDUCTOR FOR IMPLANTABLE LEAD AND METHOD OF MAKING SAME 审中-公开
标题翻译：用于可植入铅的生物电解电容器及其制造方法
公开(公告)号：US20110125240A1
公开(公告)日：2011-05-26
申请号：US12622847
申请日：2009-11-20
申请人： Yong D. Zhao , Xiaoyi Min , Virote Indravudh , Ingmar Viohl , J. Christopher Moulder , Kevin L. Morgan , Phong D. Doan
发明人： Yong D. Zhao , Xiaoyi Min , Virote Indravudh , Ingmar Viohl , J. Christopher Moulder , Kevin L. Morgan , Phong D. Doan
IPC分类号： A61N1/05
CPC分类号： A61N1/0573 , A61N1/086
摘要： A biocompatible inductor for an implantable medical lead is disclosed herein. In one embodiment the biocompatible inductor may include a biocompatible bobbin and a wire wound about a barrel of the biocompatible bobbin to form a coil. The wire may include an electrically conductive core, an electrically conductive biocompatible jacket extending over the core, and a coating of high dielectric strength insulation material extending over the jacket. Additionally, the biocompatible inductor may include medical adhesive located in gaps within the coil and a polyester shrink tube covering the coil.
摘要翻译：本文公开了用于可植入医疗引线的生物相容性电感器。在一个实施方案中，生物相容性感应器可以包括生物相容的线轴和缠绕在生物相容线圈架的筒上的线以形成线圈。线可以包括导电芯，在芯上延伸的导电生物相容性护套，以及在护套上延伸的高介电强度绝缘材料的涂层。此外，生物相容性电感器可以包括位于线圈内的间隙中的医用粘合剂和覆盖线圈的聚酯收缩管。

5. 发明授权

US07684870B1 Direct current fibrillator 失效
标题翻译：直流纤颤器
公开(公告)号：US07684870B1
公开(公告)日：2010-03-23
申请号：US11282172
申请日：2005-11-18
申请人： Mark W. Kroll , J. Christopher Moulder , Gabriel A. Mouchawar
发明人： Mark W. Kroll , J. Christopher Moulder , Gabriel A. Mouchawar
IPC分类号： A61N1/39
CPC分类号： A61N1/385
摘要： An implantable cardiac device to induce fibrillation in the heart of a patient to allow testing of the defibrillation capability of the device. The device induces fibrillation using a direct current across the heart. The shock to the heart may be applied in a method to minimize discomfort to the patient. The heart is monitored during application of the shock. The voltage of shock at the heart is gradually increased until fibrillation is induced. Once the fibrillation is detected the shock may be stopped. This results in a minimized voltage level and duration for the shock to the heart, thereby diminishing pain and discomfort to the patient.
摘要翻译：一种植入式心脏装置，用于在患者的心脏中诱导原纤维化，以允许测试该装置的除颤能力。该装置使用穿过心脏的直流电导致纤维颤动。心脏的震荡可以用于最小化患者不适的方法。在应用冲击期间监测心脏。心脏的休克电压逐渐增加，直到引发颤动。一旦检测到颤动，可能会停止休克。这导致对心脏的休克的最小电压电平和持续时间，从而减轻患者的疼痛和不适。

6. 发明授权

US07450995B2 Implantable cardiac stimulation device including an output circuit that provides arbitrarily shaped defibrillation waveforms 有权
标题翻译：可植入心脏刺激装置，包括提供任意形状除颤波形的输出电路
公开(公告)号：US07450995B2
公开(公告)日：2008-11-11
申请号：US10687386
申请日：2003-10-15
申请人： J. Christopher Moulder , Gabriel A. Mouchawar , Steven W. Badelt , Mark W. Kroll
发明人： J. Christopher Moulder , Gabriel A. Mouchawar , Steven W. Badelt , Mark W. Kroll
IPC分类号： A61N1/40
CPC分类号： H03F3/217 , A61N1/3975 , A61N1/3981
摘要： An output circuit for use in an implantable cardiac defibrillation provides an output pulse having a waveform of virtually any desired shape. The device includes a sensing circuit that senses cardiac activity. An arrhythmia detector detects fibrillation responsive to the cardiac activity signal. The device further includes an output circuit that provides a stimulation output pulse when the arrhythmia detector detects a cardiac arrhythmia. The output circuit includes an H-bridge having a pair of switching devices which control the output pulse waveform with pulse-width modulation and a second pair of switching devices that control the output pulse polarity.
摘要翻译：用于可植入心脏除颤的输出电路提供具有几乎任何期望形状的波形的输出脉冲。该装置包括感测心脏活动的感测电路。心律失常检测器响应于心脏活动信号检测原纤维。该装置还包括输出电路，其在心律不齐检测器检测到心律不齐时提供刺激输出脉冲。输出电路包括H桥，其具有控制脉冲宽度调制的输出脉冲波形的一对开关器件和控制输出脉冲极性的第二对开关器件。

7. 发明授权

US08200330B2 Responding to partial lead failure in an implantable cardioverter defibrillator 有权
标题翻译：响应植入式心律转复除颤器部分导致失败
公开(公告)号：US08200330B2
公开(公告)日：2012-06-12
申请号：US12781716
申请日：2010-05-17
申请人： Mark Kroll , Gabriel A. Mouchawar , J. Christopher Moulder , Andre Walker
发明人： Mark Kroll , Gabriel A. Mouchawar , J. Christopher Moulder , Andre Walker
IPC分类号： A61N1/39
CPC分类号： A61N1/3931 , A61N1/3621 , A61N2001/083
摘要： An implanted cardioverter defibrillator (ICD) delivers an electrical therapy signal to the heart of a patient. When ventricular fibrillation or another condition of the heart requiring high voltage therapy is sensed, the therapy signal is delivered to the heart. When a partial short-circuit or other low impedance condition occurs, an over-current protection circuit will stop delivery of a shocking pulse. The ICD will then reduce the voltage of the shocking pulse and try again to deliver electrical therapy. This process is repeated until a voltage level is found that is able to deliver the electrical therapy without causing an over-voltage condition. Alternate lead configurations may also be tried in an attempt to find a signal path that is not affected by the low impedance or short-circuit condition.
摘要翻译：植入式心律转复除颤器（ICD）向患者的心脏递送电疗治疗信号。当心室纤维性颤动或需要高压治疗的心脏的另一种情况被感测时，治疗信号传递到心脏。当发生部分短路或其他低阻抗情况时，过电流保护电路将停止输送震动脉冲。然后，ICD将降低冲击脉冲的电压，然后再次进行电疗治疗。重复该过程，直到发现能够递送电疗而不引起过电压状况的电压电平。也可以尝试替代引线配置来尝试找到不受低阻抗或短路条件影响的信号路径。

8. 发明申请

US20100228307A1 Responding to Partial Lead Failure in an Implantable Cardioverter Defibrillator 有权
标题翻译：在植入式心律转复除颤器中应对局部引导失败
公开(公告)号：US20100228307A1
公开(公告)日：2010-09-09
申请号：US12781716
申请日：2010-05-17
申请人： Mark W. Kroll , Gabriel A. Mouchawar , J. Christopher Moulder , Andre Walker
发明人： Mark W. Kroll , Gabriel A. Mouchawar , J. Christopher Moulder , Andre Walker
IPC分类号： A61N1/39
CPC分类号： A61N1/3931 , A61N1/3621 , A61N2001/083
摘要： An implanted cardioverter defibrillator (ICD) delivers an electrical therapy signal to the heart of a patient. When ventricular fibrillation or another condition of the heart requiring high voltage therapy is sensed, the therapy signal is delivered to the heart. When a partial short-circuit or other low impedance condition occurs, an over-current protection circuit will stop delivery of a shocking pulse. The ICD will then reduce the voltage of the shocking pulse and try again to deliver electrical therapy. This process is repeated until a voltage level is found that is able to deliver the electrical therapy without causing an over-voltage condition. Alternate lead configurations may also be tried in an attempt to find a signal path that is not affected by the low impedance or short-circuit condition.
摘要翻译：植入式心律转复除颤器（ICD）向患者的心脏递送电疗治疗信号。当心室纤维性颤动或需要高压治疗的心脏的另一种情况被感测时，治疗信号传递到心脏。当发生部分短路或其他低阻抗情况时，过电流保护电路将停止输送震动脉冲。然后，ICD将降低冲击脉冲的电压，然后再次进行电疗治疗。重复该过程，直到发现能够递送电疗而不引起过电压状况的电压电平。也可以尝试替代引线配置来尝试找到不受低阻抗或短路条件影响的信号路径。

9. 发明授权

US07747320B1 Responding a partial lead failure in an implantable cardioverter defibrillator 有权
标题翻译：在植入式心律转复除颤器中应对部分导致失败
公开(公告)号：US07747320B1
公开(公告)日：2010-06-29
申请号：US11433541
申请日：2006-05-12
申请人： Mark W. Kroll , Gabriel A. Mouchawar , J. Christopher Moulder , Andre Walker
发明人： Mark W. Kroll , Gabriel A. Mouchawar , J. Christopher Moulder , Andre Walker
IPC分类号： A61N1/00
CPC分类号： A61N1/3931 , A61N1/3621 , A61N2001/083
摘要： An implanted cardioverter defibrillator (ICD) delivers an electrical therapy signal to the heart of a patient. When ventricular fibrillation or another condition of the heart requiring high voltage therapy is sensed, the therapy signal is delivered to the heart. When a partial short-circuit or other low impedance condition occurs, an over-current protection circuit will stop delivery of a shocking pulse. The ICD will then reduce the voltage of the shocking pulse and try again to deliver electrical therapy. This process is repeated until a voltage level is found that is able to deliver the electrical therapy without causing an over-voltage condition. Alternate lead configurations may also be tried in an attempt to find a signal path that is not affected by the low impedance or short-circuit condition.
摘要翻译：植入式心律转复除颤器（ICD）向患者的心脏递送电疗治疗信号。当心室纤维性颤动或需要高压治疗的心脏的另一种情况被感测时，治疗信号传递到心脏。当发生部分短路或其他低阻抗情况时，过电流保护电路将停止输送震动脉冲。然后，ICD将降低冲击脉冲的电压，然后再次进行电疗治疗。重复该过程，直到发现能够递送电疗而不引起过电压状况的电压电平。也可以尝试替代引线配置来尝试找到不受低阻抗或短路条件影响的信号路径。

10. 发明申请

US20100114276A1 MRI COMPATIBLE IMPLANTABLE MEDICAL LEAD AND METHOD OF MAKING SAME 有权
标题翻译： MRI兼容可植入医疗用铅及其制造方法
公开(公告)号：US20100114276A1
公开(公告)日：2010-05-06
申请号：US12262047
申请日：2008-10-30
申请人： Xiaoyi Min , J. Christopher Moulder , Yong D. Zhao , Virote Indravudh , Ingmar Viohl
发明人： Xiaoyi Min , J. Christopher Moulder , Yong D. Zhao , Virote Indravudh , Ingmar Viohl
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/086 , H01F17/00
摘要： An implantable medical lead is disclosed herein. In one embodiment, the lead includes a body and an electrical pathway. The body may include a distal portion with an electrode and a proximal portion with a lead connector end. The electrical pathway may extend between the electrode and lead connector end and include a coiled inductor including a first portion and a second portion at least partially magnetically decoupled from the first portion. The first portion may include a first configuration having a first SRF. The second portion may include a second configuration different from the first configuration. The second configuration may have a second SRF different from the first SRF. For example, the first SRF may be near 64 MHz and the second SRF may be near 128 MHz.
摘要翻译：本文公开了可植入医疗引线。在一个实施例中，引线包括主体和电路径。主体可以包括具有电极的远端部分和具有引线连接器端部的近端部分。电路可以在电极和引线连接器端之间延伸，并且包括线圈电感器，其包括至少部分地与第一部分磁耦合的第一部分和第二部分。第一部分可以包括具有第一SRF的第一配置。第二部分可以包括不同于第一配置的第二配置。第二配置可以具有与第一SRF不同的第二SRF。例如，第一SRF可以接近64MHz，而第二SRF可以接近128MHz。

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