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1. 发明授权

US5981183A Method for amplifying and detecting of target nucleic acid sequence using thermostable enzyme 失效
标题翻译：使用热稳定酶扩增和检测靶核酸序列的方法
公开(公告)号：US5981183A
公开(公告)日：1999-11-09
申请号：US821782
申请日：1997-03-20
申请人： Yutaka Takarada , Hiroaki Inoue , Shuji Shibata , Yoshihisa Kawamura
发明人： Yutaka Takarada , Hiroaki Inoue , Shuji Shibata , Yoshihisa Kawamura
IPC分类号： C12Q1/68 , C07H21/04 , C12P19/34
CPC分类号： C12Q1/6865
摘要： In a method for amplifying the specific nucleic acid sequence, a highly specific amplification which has low possibility of non-specific hybridization can be carried out. Highly stable reagents, the activities of which do not decrease in case of supply and storage, are also provided. Thermostable enzymes are used as RNA dependent DNA polymerase, DNA dependent DNA polymerase, DNA dependent RNA polymerase and ribonuclease H, which are required for the amplification system based on replicated RNA. Especially, it is preferable that a thermostable enzyme derived from Thermus thermophilus which has RNA dependent DNA polymerase activity, DNA dependent DNA polymerase activity and ribonuclease H activity, and thermostable DNA dependent RNA polymerase are used together. By this method, inactivation of enzymes are prevented by using thermostable enzymes, and the amplification can be carried out without sequential addition of enzymes.
摘要翻译：在扩增特异性核酸序列的方法中，可以进行非特异性杂交的可能性低的高度特异性扩增。还提供了稳定的试剂，其供应和储存的活性不降低。热稳定酶用作基于复制RNA的扩增系统所需的RNA依赖性DNA聚合酶，DNA依赖性DNA聚合酶，DNA依赖性RNA聚合酶和核糖核酸酶H。特别优选共同使用具有RNA依赖性DNA聚合酶活性，DNA依赖性DNA聚合酶活性和核糖核酸酶H活性的嗜热栖热菌的热稳定性酶和耐热性DNA依赖型RNA聚合酶。通过这种方法，通过使用热稳定酶来防止酶的失活，并且可以不依次加入酶进行扩增。

2. 发明授权

US06303306B1 Method for amplifying and detecting of target nucleic acid sequence using thermostable enzyme 有权
标题翻译：使用热稳定酶扩增和检测靶核酸序列的方法
公开(公告)号：US06303306B1
公开(公告)日：2001-10-16
申请号：US09292435
申请日：1999-04-15
申请人： Yutaka Takarada , Hiroaki Inoue , Shuji Shibata , Yoshihisa Kawamura
发明人： Yutaka Takarada , Hiroaki Inoue , Shuji Shibata , Yoshihisa Kawamura
IPC分类号： C12Q168
CPC分类号： C12Q1/6865 , C12Q2527/101
摘要： In a method for amplifying the specific nucleic acid sequence, a highly specific amplification which has low possibility of non-specific hybridization can be carried out. Highly stable reagents, the activities of which do not decrease in case of supply and storage, are also provided. Thermostable enzymes are used as RNA dependent DNA polymerase, DNA dependent DNA polymerase, DNA dependent RNA polymerase and ribonuclease H, which are required for the amplification system based on replicated RNA. Especially, it is preferable that a thermostable enzyme derived from Thermus thermophilus which has RNA dependent DNA polymerase activity, DNA dependent DNA polymerase activity and ribonuclease H activity, and thermostable DNA dependent RNA polymerase are used together. By this method, inactivation of enzymes are prevented by using thermostable enzymes, and the amplification can be carried out without sequential addition of enzymes.
摘要翻译：在扩增特异性核酸序列的方法中，可以进行非特异性杂交的可能性低的高度特异性扩增。还提供了稳定的试剂，其供应和储存的活性不降低。热稳定酶用作基于复制RNA的扩增系统所需的RNA依赖性DNA聚合酶，DNA依赖性DNA聚合酶，DNA依赖性RNA聚合酶和核糖核酸酶H。特别优选共同使用具有RNA依赖性DNA聚合酶活性，DNA依赖性DNA聚合酶活性和核糖核酸酶H活性的嗜热栖热菌的热稳定性酶和耐热性DNA依赖型RNA聚合酶。通过这种方法，通过使用热稳定酶来防止酶的失活，并且可以不依次加入酶进行扩增。

3. 发明授权

US06225065B1 Kit for amplifying nucleic acid 失效
标题翻译：用于扩增核酸的试剂盒
公开(公告)号：US06225065B1
公开(公告)日：2001-05-01
申请号：US09418027
申请日：1999-10-14
申请人： Masao Kitabayashi , Taku Arakawa , Hiroaki Inoue , Bunsei Kawakami , Yoshihisa Kawamura , Tadayuki Imanaka , Masahiro Takagi , Masaaki Morikawa
发明人： Masao Kitabayashi , Taku Arakawa , Hiroaki Inoue , Bunsei Kawakami , Yoshihisa Kawamura , Tadayuki Imanaka , Masahiro Takagi , Masaaki Morikawa
IPC分类号： C12Q168
CPC分类号： C12N9/1252 , C12Q1/686
摘要： A nucleic acid amplifying enzyme having a short reaction time and high fidelity is provided. The enzyme of this invention is a thermostable DNA polymerase having a nucleic acid extension rate of at least 30 bases per second and a 3′-5′ exonuclease activity. Also provided are a method and kit for amplifying nucleic acid.
摘要翻译：提供了具有短反应时间和高保真度的核酸扩增酶。本发明的酶是具有至少30个碱基/秒的核酸延伸速率和3'-5'核酸外切酶活性的热稳定的DNA聚合酶。还提供了用于扩增核酸的方法和试剂盒。

4. 发明授权

US6054301A Methods of amplification using a thermostable DNA polymerase from the hyperthermophilic archaeon strain KOD1 and reagent kit therefor 失效
标题翻译：使用来自超嗜热古细菌菌株KOD1的热稳定DNA聚合酶的扩增方法及其试剂盒
公开(公告)号：US6054301A
公开(公告)日：2000-04-25
申请号：US656005
申请日：1996-05-24
申请人： Masao Kitabayashi , Taku Arakawa , Hiroaki Inoue , Bunsei Kawakami , Yoshihisa Kawamura , Tadayuki Imanaka , Masahiro Takagi , Masaaki Morikawa
发明人： Masao Kitabayashi , Taku Arakawa , Hiroaki Inoue , Bunsei Kawakami , Yoshihisa Kawamura , Tadayuki Imanaka , Masahiro Takagi , Masaaki Morikawa
IPC分类号： C12N15/09 , C12N1/21 , C12N9/12 , C12N15/54 , C12P21/02 , C12P21/04 , C12Q1/68 , C12R1/01 , C12R1/19 , G01N33/53 , G01N33/566 , C12P19/34 , C07K15/00
CPC分类号： C12Q1/686 , C12N9/1252
摘要： A nucleic acid amplifying enzyme having a short reaction time and high fidelity is provided. The enzyme of this invention is a thermostable DNA polymerase having a nucleic acid extension rate of at least 30 bases per second and a 3'-5' exonuclease activity. Also provided are a method and kit for amplifying nucleic acid.
摘要翻译：提供了具有短反应时间和高保真度的核酸扩增酶。本发明的酶是具有至少30个碱基/秒的核酸延伸速率和3'-5'核酸外切酶活性的热稳定的DNA聚合酶。还提供了用于扩增核酸的方法和试剂盒。

5. 发明授权

US6033859A Thermostable DNA polymerase from a hyperthermophilic archaeon strain KOD1 失效
标题翻译：来自超嗜热古细菌菌株KOD1的热稳定DNA聚合酶
公开(公告)号：US6033859A
公开(公告)日：2000-03-07
申请号：US73354
申请日：1998-05-06
申请人： Masao Kitabayashi , Taku Arakawa , Hiroaki Inoue , Bunsei Kawakami , Yoshihisa Kawamura , Tadayuki Imanaka , Masahiro Takagi , Masaaki Morikawa
发明人： Masao Kitabayashi , Taku Arakawa , Hiroaki Inoue , Bunsei Kawakami , Yoshihisa Kawamura , Tadayuki Imanaka , Masahiro Takagi , Masaaki Morikawa
IPC分类号： C12N9/12 , C12Q1/68 , C12P19/34 , C07K14/00 , C12N9/00
CPC分类号： C12N9/1252 , C12Q1/686
摘要： A nucleic acid amplifying enzyme having a short reaction time and high fidelity is provided. The enzyme of this invention is a thermostable DNA polymerase having a nucleic acid extension rate of at least 30 bases per second and a 3'-5' exonuclease activity. Also provided are a method and kit for amplifying nucleic acid.
摘要翻译：提供了具有短反应时间和高保真度的核酸扩增酶。本发明的酶是具有至少30个碱基/秒的核酸延伸速率和3'-5'核酸外切酶活性的热稳定的DNA聚合酶。还提供了用于扩增核酸的方法和试剂盒。

6. 发明授权

US09553604B2 Information processing system, information compression device, information decompression device, information processing method, and program 有权
标题翻译：信息处理系统，信息压缩装置，信息解压装置，信息处理方法和程序
公开(公告)号：US09553604B2
公开(公告)日：2017-01-24
申请号：US13262181
申请日：2010-03-19
申请人： Hiroaki Inoue
发明人： Hiroaki Inoue
IPC分类号： H03M7/30 , G11C7/10 , H04L29/12 , G11C29/00
CPC分类号： H03M7/30 , G11C7/103 , G11C29/003 , H04L29/12311
摘要： In order to improve the compression rate for configuration information including address information and data information when transmitting or storing configuration information which includes addresses and data having differing characteristics, an information compression device is provided with a compressor which receives as input and compresses the configuration information provided with the addresses and data, and a compressed information storage module for storing the configuration information which is compressed, that is, compressed configuration information, as the information to be decompressed for the user, said compressor including an information separating module for separating the configuration information into address information and data information, an address compressor and data compressor which separately compress the separated address information and data information, and a compressed information outputting module for combining the compressed address information and data information and outputting the result as compressed configuration information.
摘要翻译：为了在发送或存储具有不同特征的地址和数据的配置信息的情况下提高包括地址信息和数据信息的配置信息的压缩率，信息压缩装置设置有作为输入接收并压缩提供的配置信息的压缩器具有地址和数据的压缩信息存储模块，以及用于将被压缩的配置信息（即，压缩配置信息）存储为要为用户解压缩的信息的压缩信息存储模块，所述压缩器包括用于分离配置信息的信息分离模块地址信息和数据信息，分离地压缩分离的地址信息和数据信息的地址压缩器和数据压缩器，以及压缩信息输出模块，用于将压缩的地址信息和数据信息并将结果作为压缩配置信息输出。

7. 发明授权

US09164905B2 Semiconductor integrated circuit device, method of controlling semiconductor integrated circuit device, and cache device 有权
标题翻译：半导体集成电路器件，半导体集成电路器件的控制方法及缓存器件
公开(公告)号：US09164905B2
公开(公告)日：2015-10-20
申请号：US13393814
申请日：2010-08-18
申请人： Hiroaki Inoue
发明人： Hiroaki Inoue
IPC分类号： G06F12/00 , G06F12/08
CPC分类号： G06F12/0802 , G06F2212/1028 , Y02D10/13
摘要： There are provided a semiconductor integrated circuit device, a method of controlling a semiconductor integrated circuit device, and a cache device capable of efficiently implementing power saving, wherein the cache device includes a low-voltage operation enabling cache (200), and a small-area cache (300) having a type different from that of the cache (200), the cache (200) and the cache (300) being independently supplied with source voltage; the cache (200) being operable at a voltage lower than the lower limit voltage at which the cache (300) is operable; a cache control unit (400) operating switchable controls between a first mode allowing only the cache (200) to operate, and a second mode allowing the cache (200) or the cache (300) to operate; and the cache (200) in the first mode operating to supply a voltage below the lower limit voltage at which the cache (300) is operable, while interrupting power supply to the cache (300).
摘要翻译：提供了一种半导体集成电路器件，一种半导体集成电路器件的控制方法和能够有效地实现功率节省的高速缓存器件，其中该高速缓存器件包括一个使能高速缓存（200）的低压工作，区域缓存（300）具有与高速缓存（200）不同的类型，高速缓存（200）和高速缓存（300）被独立地提供源电压; 高速缓存（200）可操作在低于高速缓存（300）可操作的下限电压的电压; 高速缓存控制单元（400）在允许仅高速缓存（200）操作的第一模式和允许高速缓存（200）或高速缓存（300）操作的第二模式之间操作可切换控制; 以及在所述第一模式下的所述高速缓存（200）工作以提供低于所述高速缓存（300）可操作的所述下限电压的电压，同时中断向所述高速缓存（300）的电力供应。

8. 发明授权

US09160361B2 Compressed data transceiver apparatus, data compressor device, compressed data receiver device and data compression method 有权
标题翻译：压缩数据收发设备，数据压缩设备，压缩数据接收设备和数据压缩方式
公开(公告)号：US09160361B2
公开(公告)日：2015-10-13
申请号：US13379271
申请日：2010-06-01
申请人： Hiroaki Inoue
发明人： Hiroaki Inoue
IPC分类号： H03M7/30
CPC分类号： H03M7/30 , H03M7/3086 , H03M7/6023
摘要： To provide a data compression method that can achieve a high data compression ratio and does not require a buffer circuit or only requires a buffer circuit having a small storage capacity at a receiving side. A data compressor device has an adjustment and compression tool operable to switch a plurality of code words having different code lengths and compress input data at a rate that does not exceed a predetermined receiving speed.
摘要翻译：为了提供可以实现高数据压缩比并且不需要缓冲电路或仅需要在接收侧具有小存储容量的缓冲电路的数据压缩方法。数据压缩装置具有可操作以切换具有不同代码长度的多个代码字的调整和压缩工具，并以不超过预定接收速度的速率压缩输入数据。

9. 发明授权

US09109344B2 Working machine 有权
标题翻译：工作机
公开(公告)号：US09109344B2
公开(公告)日：2015-08-18
申请号：US13321599
申请日：2010-05-19
申请人： Kouya Iizuka , Satoru Nishimura , Hiroshi Yoshida , Hiroaki Inoue
发明人： Kouya Iizuka , Satoru Nishimura , Hiroshi Yoshida , Hiroaki Inoue
IPC分类号： E02F9/22 , E02F9/20 , F15B11/17
CPC分类号： E02F9/2004 , E02F9/2228 , E02F9/2282 , E02F9/2285 , E02F9/2292 , F15B11/17 , F15B2211/324 , F15B2211/526
摘要： In the working machine, first and second pilot flow paths are directly or indirectly connected to a tank flow path (52). A first restrictor is disposed between the first pilot flow path and the tank flow path. A second restrictor is disposed between the second pilot flow path and the tank flow path. An actuator control unit is configured to control an actuator based on a hydraulic pressure detected by a first hydraulic pressure detector unit and that detected by a second hydraulic pressure detector unit sensor.
摘要翻译：在工作机器中，第一和第二先导流动路径直接或间接地连接到罐流动路径（52）。第一限流器设置在第一先导流路和箱流路之间。第二限流器设置在第二先导流路和罐流路之间。执行器控制单元被配置为基于由第一液压检测器单元检测到的液压并且由第二液压检测器单元传感器检测到的液压来控制致动器。

10. 发明授权

US08473702B2 Information processing apparatus, execution environment transferring method and program thereof 有权
标题翻译：信息处理装置，执行环境转移方法及程序
公开(公告)号：US08473702B2
公开(公告)日：2013-06-25
申请号：US12602871
申请日：2008-06-05
申请人： Hiroaki Inoue , Tsuyoshi Abe , Junji Sakai , Masato Edahiro
发明人： Hiroaki Inoue , Tsuyoshi Abe , Junji Sakai , Masato Edahiro
IPC分类号： G06F12/00
CPC分类号： G06F9/44505 , G06F9/4856
摘要： Provided is an information processing device which enables transfer of an execution environment in a short time period without degrading basic performance of an execution environment and without requiring a large amount of memory.The information processing device comprises a basic side CPU 100 for executing basic processing and an addition side CPU 200 for executing additional processing, in which a transfer management unit 300 provided on the basic side CPU 100 transfers execution environment data 1000 including constitution information of an execution environment 30 of the additional processing to be executed on the addition side CPU and data in a memory corresponding to the execution environment to other information processing device and restores the execution environment to re-start the addition side CPU based on the received execution environment data 1000.
摘要翻译：提供一种能够在短时间内传送执行环境而不降低执行环境的基本性能而不需要大量存储器的信息处理装置。信息处理装置包括用于执行基本处理的基本侧CPU 100和用于执行附加处理的附加侧CPU200，其中设置在基本侧CPU 100上的传送管理单元300传送包括执行的结构信息的执行环境数据1000 在附加侧CPU执行的附加处理的环境30和与执行环境相对应的存储器中的数据到其他信息处理装置，并且基于接收到的执行环境数据1000恢复执行环境以重新启动加法侧CPU 。

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