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1. 发明授权

US4536391A Process for preparing urokinase complex 失效
标题翻译：制备尿激酶复合物的方法
公开(公告)号：US4536391A
公开(公告)日：1985-08-20
申请号：US551841
申请日：1983-11-15
申请人： Wasei Miyazaki , Tsuneo Sato , Yasuo Nakayama , Tadao Sato
发明人： Wasei Miyazaki , Tsuneo Sato , Yasuo Nakayama , Tadao Sato
IPC分类号： A61K38/00 , C07D207/44 , C07D207/452 , C07D207/46 , C12N9/72 , C12N11/06 , A61K37/48 , A61K37/00 , C07G7/00
CPC分类号： C07D207/452 , C07D207/46 , C12N11/06 , C12N9/6462 , C12Y304/21073 , A61K38/00
摘要： This invention provides a process for preparing a fibrin-adsorable protein-urokinase complex characterized by reacting a protein adsorbable by fibrin with urokinase in the presence of a protein coupling reagent represented by the formula ##STR1## wherein R is phenylene or cycloalkylene, A is lower alkylene, B is lower alkylene which may optionally be substituted by lower alkylthio or phenyl-lower alkylthio, and l, m and n are each 0 or 1 provided that l, m and n are not 0 at the same time.The complex is useful as a thrombolytic agent.
摘要翻译：本发明提供了一种制备纤维蛋白可吸附的蛋白质 - 尿激酶复合物的方法，其特征在于在由下式表示的蛋白质偶联试剂存在下使由纤维蛋白可吸附的蛋白质与尿激酶反应，其中R是亚苯基或亚环烷基，A较低亚烷基，B是可以被低级烷硫基或苯基 - 低级烷硫基取代的低级亚烷基，l，m和n各自为0或1，条件是l，m和n不同时为0。该复合物可用作溶栓剂。

2. 发明授权

US4545988A Urokinase-plasmin complex adsorbable by fibrin and process for preparing same 失效
标题翻译：由纤维蛋白吸附的尿激酶 - 纤溶酶复合物及其制备方法
公开(公告)号：US4545988A
公开(公告)日：1985-10-08
申请号：US683024
申请日：1984-12-18
申请人： Yasuo Nakayama , Wasei Miyazaki , Masanao Shinohara
发明人： Yasuo Nakayama , Wasei Miyazaki , Masanao Shinohara
IPC分类号： C12N9/68 , A61K38/00 , A61K38/46 , A61K38/48 , A61K47/48 , A61P7/02 , C12N9/72 , A61K37/54 , C12N9/96
CPC分类号： C12N9/6462 , A61K47/48238 , C12Y304/21073 , A61K38/00
摘要： This invention provides a urokinase complex adsorbable by fibrin characterized in that it comprises heavy chain of high molecular weight urokinase as coupled with heavy chain of plasmin by one or more S-S bonds and a process for preparing the same.
摘要翻译：本发明提供一种由纤维蛋白吸附的尿激酶复合物，其特征在于，其包含与一种或多种S-S键连接的纤溶酶重链的高分子量尿激酶重链及其制备方法。

3. 发明授权

US5348858A Monoclonal antibody specific for human interleukin-1.beta. and method for detection of biologically active human interleukin-1.beta. 失效
标题翻译：用于人白细胞介素-1β的单克隆抗体和用于检测生物活性的人白细胞介素-1β的方法
公开(公告)号：US5348858A
公开(公告)日：1994-09-20
申请号：US815875
申请日：1992-01-06
申请人： Setsuyoshi Uetsuki , Osamu Sato , Yasuo Nakayama , Yoshikatsu Hirai
发明人： Setsuyoshi Uetsuki , Osamu Sato , Yasuo Nakayama , Yoshikatsu Hirai
IPC分类号： C07K14/545 , C07K16/24 , C12N5/20 , C12N15/06 , C12P21/08 , G01N33/68 , G01N33/53 , C07K15/28
CPC分类号： G01N33/6869 , C07K14/545 , C07K16/245
摘要： The present invention provides a monoclonal antibody characterized in that the antibody has specific reactivity on human IL-1.beta., and a process for producing the antibody. The invention also provides a method for detection of biologically active human IL-1.beta..
摘要翻译：本发明提供了一种单克隆抗体，其特征在于该抗体对人IL-1β具有特异性反应性，以及该抗体的制备方法。本发明还提供了用于检测生物活性的人IL-1β的方法。

4. 发明授权

US07047555B1 In-building CATV system, down-converter, up-converter and amplifier 失效
标题翻译：建筑内CATV系统，下变频器，上变频器和放大器
公开(公告)号：US07047555B1
公开(公告)日：2006-05-16
申请号：US09621527
申请日：2000-07-21
申请人： Mitsuhiko Inaguma , Shigemitsu Toriyama , Yasuo Nakayama
发明人： Mitsuhiko Inaguma , Shigemitsu Toriyama , Yasuo Nakayama
IPC分类号： H04N7/16 , H04N7/18 , H04N7/173
CPC分类号： H04N7/17309 , H04N7/102 , H04N7/106 , H04N21/42676
摘要： In order to correctly perform frequency conversion without using a pilot signal from an external system in a CATV system in which an upward signal is converted to a high frequency in-building upward signal using an up-converter and the in-building upward signal is converted to the original upward signal using a down-converter, there is proposed a down-converter provided with a reference oscillation circuit for generating a reference signal with a frequency lower than that of a downward signal or the in-building upward signal. The in-building upward signal is frequency-converted using the reference signal and the reference signal is transmitted to a transmission line of the terminal side. A bi-directional amplifier on the transmission line can not only amplify the downward signal and the in-building upward signal bi-directionally but also transmit the reference signal to an up-converter of the terminal side. The transmitted reference signal is extracted in the up-converter and the upward signal is frequency-converted to the in-building upward signal.
摘要翻译：为了在不使用来自CATV系统中的外部系统的导频信号的情况下正确地执行变频，其中使用上变频器将向上信号转换为高频建筑内向上信号，并且建筑内向上信号被转换使用下变频器的原始上行信号，提出了一种具有参考振荡电路的下变频器，用于产生频率低于下行信号或建筑内向上信号的参考信号。建筑内向上信号使用参考信号进行频率转换，参考信号被发送到终端侧的传输线。传输线上的双向放大器不仅可以双向放大向下信号和建筑内向上信号，而且可以将参考信号发送到终端侧的上变频器。在上变频器中提取发送的参考信号，并将向上信号频率转换为建筑内向上信号。

5. 发明授权

US5534251A Stabilized il-1.alpha. medicinal composition 失效
标题翻译：稳定的il-1α药物组合物
公开(公告)号：US5534251A
公开(公告)日：1996-07-09
申请号：US193182
申请日：1994-02-14
申请人： Yuji Sugahara , Yasuo Nakayama
发明人： Yuji Sugahara , Yasuo Nakayama
IPC分类号： A61K9/08 , A61K9/19 , A61K38/00 , A61K38/20 , A61K47/26 , A61K47/42 , C07K14/52 , C07K14/54 , C07K14/545 , C07K14/76 , A61K45/05
CPC分类号： A61K9/19 , A61K38/2006 , A61K47/26 , A61K47/42
摘要： The invention provides a stabilized IL-1.alpha. medicinal composition comprising an IL-1.alpha. active substance, serum albumin and a saccharide. The medicinal composition of the invention has very desirable characteristics in terms of the stability of its active ingredient IL-1.alpha. active substance, rendering it stable throughout its processing into various dosage forms, such as freezing and freeze-drying, and for a long time after production under the usual storage conditions, thus being of great utility value in the relevant field.
摘要翻译： PCT No.PCT / JP92 / 00983 Sec。 371日期1994年2月14日 102（e）1994年2月14日PCT PCT 1992年7月31日PCT公布。公开号WO93 / 03747 日本1993年3月4日。本发明提供包含IL-1α活性物质，血清白蛋白和糖的稳定的IL-1α药物组合物。本发明的药物组合物在其活性成分IL-1α活性物质的稳定性方面具有非常理想的特性，使其在整个加工过程中稳定，成为各种剂型，如冷冻和冷冻干燥，以及长时间在通常的储存条件下生产后，在相关领域具有很大的实用价值。

6. 发明授权

US5070604A Method for soldering two kinds of parts on one-side printed board 失效
标题翻译：在单面印刷电路板上焊接两种零件的方法
公开(公告)号：US5070604A
公开(公告)日：1991-12-10
申请号：US629140
申请日：1990-12-18
申请人： Mitsuyuki Banba , Hideki Matsuo , Yasuo Nakayama , Hideo Suzuki
发明人： Mitsuyuki Banba , Hideki Matsuo , Yasuo Nakayama , Hideo Suzuki
IPC分类号： H05K3/30 , H05K3/34
CPC分类号： H05K3/306 , H05K3/3415 , H05K2203/1484 , H05K2203/1572 , H05K3/305 , H05K3/3447 , H05K3/3484 , Y02P70/613 , Y10T29/49139 , Y10T29/49144
摘要： The present invention relates to a method for soldering two kinds of parts, parts with leads and chip parts, on one-side printed board, comprising coating a cream solder on a plurality of points of a wiring pattern surface of one-side printed board and coating an adhesive for adhering parts with leads on a non-wiring pattern, adhering parts with leads to said non-wiring pattern surface by said adhesive, passing leads of the parts with leads through lead insert holes of said one-side printed board to insert the same into one cream solder on the wiring pattern surface from the side of the non-wiring pattern surface, mounting chip parts on the other cream solder on said wiring pattern surface, thereafter heating at once the whole cream solder on the wiring pattern to simultaneously reflow-solder the parts with leads and chip parts whereby the parts with leads and the chip parts can be simultaneously soldered by a single reflow soldering step.
摘要翻译：本发明涉及在一侧印刷电路板上焊接两种部件，引线和芯片部件的部件的方法，包括在一侧印刷电路板的布线图形表面的多个点上涂覆膏状焊膏，以及涂布粘合剂用于以非布线图案的引线粘合部件，用引线将部件与引线粘合到所述非布线图案表面上，所述粘合剂将引线通过引线穿过所述单面印刷板的引线插入孔插入在非布线图案表面侧的布线图案表面上形成一个膏状焊膏，将芯片部分安装在所述布线图案表面上的另一个膏状焊料上，然后同时加热布线图案上的整个奶油焊料用引线和芯片部件回流焊接部件，由此可以通过单个回流焊步骤同时焊接引线部分和芯片部件。

7. 发明授权

US4400087A Light measuring circuit 失效
标题翻译：光测电路
公开(公告)号：US4400087A
公开(公告)日：1983-08-23
申请号：US262895
申请日：1981-05-12
申请人： Yasuo Nakayama
发明人： Yasuo Nakayama
IPC分类号： G03B7/081 , G01J1/46 , G03B7/083 , G03B15/05 , H05B41/32 , H05B41/14
CPC分类号： H05B41/325 , G01J1/46
摘要： A light measuring element which is provided with a pulse signal generator for generating pulse signals the duty ratio of which varies in accordance with a coefficient related to the exposure for photographing, a switching element which is driven by the output pulse signals from the pulse signal generator, and a light integrating circuit which includes a photo detector and an integrating capacitor and provides the voltage across the integrating capacitor as a light measure output. The light integrating circuit performs an intermittent light integrating operation by the action of the switching element. The integration period of the light integrating circuit is varied by varying the duty ratio of drive signals to the switching element which are supplied from a pulse signal generator, which duty ratio varies with a coefficient related to the proper exposure for photographing.
摘要翻译：一种光测量元件，其设置有用于产生脉冲信号的脉冲信号，所述脉冲信号的占空比根据与用于拍摄的曝光有关的系数而变化;开关元件，其由来自脉冲信号发生器的输出脉冲信号驱动以及包含光检测器和积分电容器的光积分电路，并且将积分电容器两端的电压提供为光测量输出。光积分电路通过开关元件的动作进行间歇光积分动作。通过改变从脉冲信号发生器提供的对开关元件的驱动信号的占空比来改变光积分电路的积分周期，该占空比随与用于拍摄的适当曝光相关的系数而变化。

8. 发明授权

US4298826A Automatic flash unit 失效
标题翻译：自动闪光灯组件
公开(公告)号：US4298826A
公开(公告)日：1981-11-03
申请号：US87469
申请日：1979-10-22
申请人： Yasuo Nakayama
发明人： Yasuo Nakayama
IPC分类号： H05B41/32
CPC分类号： H05B41/325
摘要： A series control type automatic flash unit which is capable of achieving completely controlled flashing by controlling electrical energy supplied from a main capacitor to a discharge lamp by means of a first switching element connected in series with the discharge lamp. A series circuit of a second switching element conducted by a light control signal derived from light control means and a commutation capacitor is connected in parallel with the series circuit of the discharge lamp and the first switching element, and the commutation capacitor is charged by charging means in a predetermined polarity. This charging is performed at least prior to the state of commutation, and upon conduction of the second switching element by the light control signal, stored charges of the commutation capacitor are applied via the second switching element to the first switching element to place it in a reverse biased condition. As a consequence, the first switching element is turned OFF to stop lighting of the discharge lamp. Since the second switching element which still remains conductive at that time is connected in parallel with the discharge lamp, no unnecessary discharge current flows in the discharge lamp immediately after turning OFF of the first switching element; thus, the quantity of light emitted by the discharge lamp can be controlled with high precision.
摘要翻译：一种串联控制型自动闪光单元，其能够通过与通过与放电灯串联连接的第一开关元件控制从主电容器提供给放电灯的电能来实现完全控制的闪光。通过由光控制装置和换向电容器导出的光控制信号传导的第二开关元件的串联电路与放电灯和第一开关元件的串联电路并联连接，并且换向电容器由充电装置以预定的极性。该充电至少在换向状态之前进行，并且在通过光控制信号导通第二开关元件时，通过第二开关元件将换向电容器的存储电荷施加到第一开关元件以将其置于反向偏置状态。结果，第一开关元件被断开以停止放电灯的点亮。由于此时仍然保持导通的第二开关元件与放电灯并联连接，因此在第一开关元件断开之后立即不会在放电灯中流过不必要的放电电流; 因此，可以高精度地控制由放电灯发出的光量。

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