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1. 发明授权

US08202294B2 Clip applier and methods of use 有权
标题翻译：夹子施放器和使用方法
公开(公告)号：US08202294B2
公开(公告)日：2012-06-19
申请号：US12973204
申请日：2010-12-20
申请人： Ronald Jabba , W. Martin Belef
发明人： Ronald Jabba , W. Martin Belef
IPC分类号： A61B17/08 , A61B17/10
CPC分类号： A61B17/068 , A61B17/0057 , A61B17/064 , A61B17/0644 , A61B17/1227 , A61B2017/00336 , A61B2017/00637 , A61B2017/00672 , A61B2017/00862 , A61B2017/22038 , A61B2090/037 , A61B2090/08021
摘要： An apparatus for delivering a closure element into an opening formed in a blood vessel or other body lumen and methods for manufacturing and using same. The apparatus is configured to retain the closure element such that the closure element is disposed substantially within the apparatus. The apparatus also can engage, and position the closure element substantially adjacent to, the blood vessel wall adjacent to the opening. During deployment of the closure element, the apparatus expands the closure element beyond a natural cross-section of the closure element such that the closure element, when deployed, is configured to engage a significant amount of the blood vessel wall and/or tissue. Engaging the blood vessel wall and/or tissue, the closure element is further configured to return to the natural cross-section, thereby drawing the engaged blood vessel wall and/or tissue substantially closed and/or sealed, such that hemostasis within the opening is enhanced.
摘要翻译：一种用于将闭合元件输送到形成在血管或其他体腔中的开口中的装置及其制造和使用方法。该装置构造成保持封闭元件，使得封闭元件基本上设置在该装置内。该装置还可以将封闭件基本上邻近开口附近的血管壁接合并定位。在封闭元件的展开过程中，该装置将闭合元件膨胀超过封闭元件的自然横截面，使得封闭元件在展开时构造成与大量的血管壁和/或组织接合。接合血管壁和/或组织，闭合元件进一步构造成返回到自然横截面，从而将所接合的血管壁和/或组织基本上闭合和/或密封，使得开口内止血增强。

2. 发明申请

US20110144664A1 CLIP APPLIER AND METHODS OF USE 有权
标题翻译：夹具应用和使用方法
公开(公告)号：US20110144664A1
公开(公告)日：2011-06-16
申请号：US12973204
申请日：2010-12-20
申请人： Ronald Jabba , W. Martin Belef
发明人： Ronald Jabba , W. Martin Belef
IPC分类号： A61B17/10
CPC分类号： A61B17/068 , A61B17/0057 , A61B17/064 , A61B17/0644 , A61B17/1227 , A61B2017/00336 , A61B2017/00637 , A61B2017/00672 , A61B2017/00862 , A61B2017/22038 , A61B2090/037 , A61B2090/08021
摘要： An apparatus for delivering a closure element into an opening formed in a blood vessel or other body lumen and methods for manufacturing and using same. The apparatus is configured to retain the closure element such that the closure element is disposed substantially within the apparatus. The apparatus also can engage, and position the closure element substantially adjacent to, the blood vessel wall adjacent to the opening. During deployment of the closure element, the apparatus expands the closure element beyond a natural cross-section of the closure element such that the closure element, when deployed, is configured to engage a significant amount of the blood vessel wall and/or tissue. Engaging the blood vessel wall and/or tissue, the closure element is further configured to return to the natural cross-section, thereby drawing the engaged blood vessel wall and/or tissue substantially closed and/or sealed, such that hemostasis within the opening is enhanced.
摘要翻译：一种用于将闭合元件输送到形成在血管或其他体腔中的开口中的装置及其制造和使用方法。该装置构造成保持封闭元件，使得封闭元件基本上设置在该装置内。该装置还可以将封闭件基本上邻近开口附近的血管壁接合并定位。在封闭元件的展开过程中，该装置将闭合元件膨胀超过封闭元件的自然横截面，使得封闭元件在展开时构造成与大量的血管壁和/或组织接合。接合血管壁和/或组织，闭合元件进一步构造成返回到自然横截面，从而将所接合的血管壁和/或组织基本上闭合和/或密封，使得开口内止血增强。

3. 发明授权

US07857828B2 Clip applier and methods of use 有权
标题翻译：夹子施放器和使用方法
公开(公告)号：US07857828B2
公开(公告)日：2010-12-28
申请号：US11048503
申请日：2005-02-01
申请人： Ronald Jabba , W. Martin Belef
发明人： Ronald Jabba , W. Martin Belef
IPC分类号： A61B17/08 , A61B17/10
CPC分类号： A61B17/068 , A61B17/0057 , A61B17/064 , A61B17/0644 , A61B17/1227 , A61B2017/00336 , A61B2017/00637 , A61B2017/00672 , A61B2017/00862 , A61B2017/22038 , A61B2090/037 , A61B2090/08021
摘要： An apparatus for delivering a closure element into an opening formed in a blood vessel or other body lumen and methods for manufacturing and using same. The apparatus is configured to retain the closure element such that the closure element is disposed substantially within the apparatus. The apparatus also can engage, and position the closure element substantially adjacent to, the blood vessel wall adjacent to the opening. During deployment of the closure element, the apparatus expands the closure element beyond a natural cross-section of the closure element such that the closure element, when deployed, is configured to engage a significant amount of the blood vessel wall and/or tissue. Engaging the blood vessel wall and/or tissue, the closure element is further configured to return to the natural cross-section, thereby drawing the engaged blood vessel wall and/or tissue substantially closed and/or sealed, such that hemostasis within the opening is enhanced.
摘要翻译：一种用于将闭合元件输送到形成在血管或其他体腔中的开口中的装置及其制造和使用方法。该装置构造成保持封闭元件，使得封闭元件基本上设置在该装置内。该装置还可以将封闭件基本上邻近开口附近的血管壁接合并定位。在封闭元件的展开过程中，该装置将闭合元件膨胀超过封闭元件的自然横截面，使得封闭元件在展开时构造成与大量的血管壁和/或组织接合。接合血管壁和/或组织，闭合元件进一步构造成返回到自然横截面，从而将所接合的血管壁和/或组织基本上闭合和/或密封，使得开口内止血增强。

4. 发明授权

US09050087B2 Integrated vascular device with puncture site closure component and sealant and methods of use 有权
公开(公告)号：US09050087B2
公开(公告)日：2015-06-09
申请号：US12106937
申请日：2008-05-14
申请人： Richard S. Ginn , W. Martin Belef
发明人： Richard S. Ginn , W. Martin Belef
IPC分类号： A61B17/08 , A61B17/10 , A61B17/128 , A61B17/00 , A61B17/064 , A61M25/06
CPC分类号： A61B17/10 , A61B17/00491 , A61B17/0057 , A61B17/064 , A61B17/0643 , A61B17/083 , A61B17/128 , A61B17/1285 , A61B2017/00637 , A61B2017/00663 , A61B2017/00668 , A61B2017/00672 , A61B2017/00862 , A61B2017/0641 , A61M25/0662
摘要： Apparatus and methods are provided for use in sealing a vascular puncture site. The invention comprises an integrated vascular device having a sheath with a closure component and puncture sealant. The closure component is disposed on and advanceable over the exterior of the sheath and may comprise any of a variety of apparatus suited for closing a vascular puncture. Once the closure component has been actuated to close the puncture, sealant is introduced to seal the puncture. The sheath and closure component are then removed from the patient.

5. 发明申请

US20120041480A1 Systems and Methods for Treating Septal Defects 审中-公开
标题翻译：系统和方法治疗间隔缺损
公开(公告)号：US20120041480A1
公开(公告)日：2012-02-16
申请号：US13282392
申请日：2011-10-26
申请人： Ryan Abbott , W. Martin Belef , Dean Carson , Rajiv Doshi , Richard S. Ginn , Ronald J. Jabba , William A. Gray
发明人： Ryan Abbott , W. Martin Belef , Dean Carson , Rajiv Doshi , Richard S. Ginn , Ronald J. Jabba , William A. Gray
IPC分类号： A61B17/10
CPC分类号： A61B17/0057 , A61B17/064 , A61B17/221 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61B2017/0649 , A61B2017/22047 , A61B2017/2926 , A61B2017/306
摘要： A system for treating a septal defect having an implantable treatment apparatus and devices for delivering the implantable treatment apparatus and methods for treating a septal defect are provided. The implantable treatment apparatus is preferably implantable through a septal wall or portion thereof. The treatment system can include a flexible elongate body member, a delivery device configured to deliver the implantable apparatus, a stabilization device configured to stabilize the body member and a positioning device configured to position the delivery device in a desired location.
摘要翻译：提供了一种用于治疗具有可植入治疗装置的间隔缺损的系统和用于递送可植入治疗装置的装置和用于治疗间隔缺损的方法。可植入治疗装置优选通过中隔壁或其部分植入。治疗系统可以包括柔性细长主体构件，配置成输送可植入装置的输送装置，被配置为使身体构件稳定的稳定装置和构造成将输送装置定位在期望位置的定位装置。

6. 发明申请

US20100305584A1 Suture-Based Systems and Methods for Treating Septal Defects 审中-公开
标题翻译：基于缝合的系统和治疗间隔缺损的方法
公开(公告)号：US20100305584A1
公开(公告)日：2010-12-02
申请号：US12850910
申请日：2010-08-05
申请人： W. Martin Belef , Dean Carson , Richard S. Ginn , Ronald J. Jabba
发明人： W. Martin Belef , Dean Carson , Richard S. Ginn , Ronald J. Jabba
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B2017/00575 , A61B2017/0404 , A61B2017/0406 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0448 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0462 , A61B2017/0464 , A61B2017/047 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052
摘要： A system for treating a septal defect having a suture-like implantable treatment apparatus and devices for delivering the implantable treatment apparatus and methods for treating a septal defect are provided. The suture-like apparatus is preferably implantable through a septal wall or portion thereof. The treatment system can include a flexible elongate body member, a delivery device configured to deliver the suture-like apparatus, a stabilization device configured to stabilize the delivery device and a positioning device configured to position the delivery device in a desired location. The suture-like device can include a suture body coupled with one or more lock devices or anchor devices.
摘要翻译：提供了一种用于治疗具有缝合线可植入治疗装置的间隔缺损的系统和用于递送可植入治疗装置的装置和用于治疗间隔缺损的方法。缝线状装置优选通过隔壁或其部分植入。处理系统可以包括柔性细长主体构件，配置成输送缝合线状装置的输送装置，被配置为稳定输送装置的稳定装置和被配置成将输送装置定位在期望位置的定位装置。缝合线状装置可以包括与一个或多个锁定装置或锚定装置连接的缝线体。

7. 发明授权

US07842065B2 Rapid exchange sheath for deployment of medical devices and methods of use 有权
标题翻译：用于部署医疗器械的快速交换护套和使用方法
公开(公告)号：US07842065B2
公开(公告)日：2010-11-30
申请号：US11611272
申请日：2006-12-15
申请人： W. Martin Belef , Ross S. Tsugita
发明人： W. Martin Belef , Ross S. Tsugita
IPC分类号： A61M29/00
CPC分类号： A61B17/221 , A61F2/013 , A61F2/958 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0093 , A61M25/0169 , A61M25/0172 , A61M25/0662 , A61M25/104 , A61M2025/018 , A61M2025/0183
摘要： A rapid exchange sheath comprising an elongate tubular member, a guidewire, and support wire having an expandable filter at a distal end. The guidewire passes through a first opening at a distal end of the tubular member and a second opening a short distance proximal from the distal end. The support wire is received in a lumen of the tubular member, or, in certain embodiments, extends proximally through a third opening a short distance proximal from the distal end. Methods of using the sheaths for deploying and/or exchanging medical device(s) in a patient's vessel are also disclosed.
摘要翻译：一种快速交换护套，其包括细长管状构件，导丝和在远端具有可扩张过滤器的支撑线。导丝穿过管状构件的远端处的第一开口和远离近端的短距离的第二开口。支撑线被容纳在管状构件的内腔中，或者在某些实施例中，近端延伸通过距离远端近的短距离的第三开口。还公开了在病人血管中使用用于部署和/或更换医疗装置的护套的方法。

8. 发明申请

US20100262183A1 SYSTEMS DEVICES AND METHODS FOR ACHIEVING TRANSVERSE ORIENTATION IN THE TREATMENT OF SEPTAL DEFECTS 审中-公开
标题翻译：系统设备和方法，用于在解决缺陷中实现横向定向
公开(公告)号：US20100262183A1
公开(公告)日：2010-10-14
申请号：US12740667
申请日：2008-11-05
申请人： Ryan Abbott , W. Martin Belef , Dean Carson , Ronald J. Jabba , Anthony J. Pantages
发明人： Ryan Abbott , W. Martin Belef , Dean Carson , Ronald J. Jabba , Anthony J. Pantages
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B17/3403 , A61B2017/00575 , A61B2017/3405 , A61M25/00 , A61M25/09
摘要： Systems, devices and methods for treating internal tissue defects, such as septal defects, with implantable devices are provided. Elongate delivery systems for these implantable devices are configured to achieve a transverse orientation with respect to the defect site, allowing the implantable apparatus to be delivered from an elongate device in an efficient manner.
摘要翻译：提供了用可植入装置来治疗内部组织缺陷如间隔缺损的系统，装置和方法。用于这些可植入装置的伸长递送系统被配置成实现相对于缺陷部位的横向取向，从而允许可植入装置以有效的方式从细长装置输送。

9. 发明申请

US20090088796A1 Systems and Methods for Treating Septal Defects 审中-公开
标题翻译：系统和方法治疗间隔缺损
公开(公告)号：US20090088796A1
公开(公告)日：2009-04-02
申请号：US12260932
申请日：2008-10-29
申请人： Ryan Abbott , W. Martin Belef , Dean Carson , Rajiv Doshi , Richard S. Ginn , Ronald J. Jabba , William A. Gray
发明人： Ryan Abbott , W. Martin Belef , Dean Carson , Rajiv Doshi , Richard S. Ginn , Ronald J. Jabba , William A. Gray
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/064 , A61B17/221 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61B2017/0649 , A61B2017/22047 , A61B2017/2926 , A61B2017/306
摘要： A system for treating a septal defect having an implantable treatment apparatus and devices for delivering the implantable treatment apparatus and methods for treating a septal defect are provided. The implantable treatment apparatus is preferably implantable through a septal wall or portion thereof. The treatment system can include a flexible elongate body member, a delivery device configured to deliver the implantable apparatus, a stabilization device configured to stabilize the body member and a positioning device configured to position the delivery device in a desired location.
摘要翻译：提供了一种用于治疗具有可植入治疗装置的间隔缺损的系统和用于递送可植入治疗装置的装置和用于治疗间隔缺损的方法。可植入治疗装置优选通过中隔壁或其部分植入。治疗系统可以包括柔性细长主体构件，配置成输送可植入装置的输送装置，被配置为使身体构件稳定的稳定装置和构造成将输送装置定位在期望位置的定位装置。

10. 发明授权

US07488289B2 Imaging catheter and methods of use for ultrasound-guided ablation 有权
公开(公告)号：US07488289B2
公开(公告)日：2009-02-10
申请号：US09967872
申请日：2001-09-28
申请人： Veijo T. Suorsa , W. Martin Belef , Niyazi Beyhan , Donald S. Mamayek
发明人： Veijo T. Suorsa , W. Martin Belef , Niyazi Beyhan , Donald S. Mamayek
IPC分类号： A61B8/14 , A61B8/00
CPC分类号： A61B8/12 , A61B8/0841 , A61B8/445 , A61B8/4461
摘要： The present invention provides ultrasound imaging catheters, systems and methods for their use which will be particularly useful to monitor the positioning of ablation catheters. In one embodiment, an imaging catheter (10) includes a catheter body (11) having a distal end (12), a proximal end (14) and a longitudinal axis (16). A transducer (20) is rotatably coupled to the distal end. The transducer has an axis of rotation (24) that is at a non-zero angle relative to the catheter body longitudinal axis. Such a configuration provides an exemplary side-looking imaging catheter.

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