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1. 发明授权

US07880560B2 Directional coupler and a receiving or transmitting device 有权
标题翻译：定向耦合器和接收或发送装置
公开(公告)号：US07880560B2
公开(公告)日：2011-02-01
申请号：US12505739
申请日：2009-07-20
申请人： Pinghua He , Xinlu Li , Jianjun Chen , Zhaolu Wei , Gang Ju
发明人： Pinghua He , Xinlu Li , Jianjun Chen , Zhaolu Wei , Gang Ju
IPC分类号： H01P5/18 , H01P5/08
CPC分类号： H01P5/18 , H01P5/107
摘要： A directional coupler and a receiving or transmitting device. The directional coupler includes: a primary signal line composed of a metal rod; and a coupled signal line composed of a microstrip line in a curved shape on a printed circuit board; wherein the medium between the metal rod and the microstrip line is air. Compared with existing directional coupler, the directional coupler of the embodiments of the disclosure has a lower transmitting loss, a large power capacity, and a high directional qualification. The directional coupler is capable of ensuring a higher passive intermodulation qualification. The advantages of the embodiments of the present disclosure are easier assembly, good uniformity of the qualifications, and adaptability for various application environments. The directional coupler of the disclosure ensures different parameter qualifications, and is simple to assemble, so that the low cost is achieved.
摘要翻译：定向耦合器和接收或发送装置。定向耦合器包括：由金属杆构成的主信号线; 以及由印刷电路板上的弯曲形状的微带线组成的耦合信号线; 其中金属棒和微带线之间的介质是空气。与现有的定向耦合器相比，本发明的实施例的定向耦合器具有较低的发射损耗，较大的功率容量和较高的方向性鉴定。定向耦合器能够确保更高的无源互调质量。本公开的实施例的优点是更容易组装，资格的良好均匀性以及针对各种应用环境的适应性。本公开的定向耦合器确保不同的参数资格，并且组装简单，从而实现了低成本。

2. 发明授权

US08740854B2 Stopper and plunger rod for a pre-filled syringe 有权
标题翻译：用于预填充注射器的止动器和柱塞杆
公开(公告)号：US08740854B2
公开(公告)日：2014-06-03
申请号：US12133076
申请日：2008-06-04
申请人： Eric Schiller , Michael V. Quinn , Johanna Torres , E Guan , Anthony Economou , Gang Ju
发明人： Eric Schiller , Michael V. Quinn , Johanna Torres , E Guan , Anthony Economou , Gang Ju
IPC分类号： A61M5/315
CPC分类号： A61M5/31513 , A61M5/31511 , A61M5/31515 , A61M2005/31521 , A61M2005/31523
摘要： A plunger rod adapted for attachment with a stopper for use with a syringe barrel is disclosed. The plunger rod includes an elongated member having a front end and a back end, the plunger rod extending along a longitudinal axis. The plunger rod includes at least one deflecting arm associated with the front end of the elongated member. The deflecting arm is capable of deflecting radially inward during insertion of the plunger rod into a stopper, and deflecting outward into contact with an inner surface of the stopper after insertion to lock the plunger rod within the stopper.
摘要翻译：公开了一种适用于与注射器筒一起使用的止动件的柱塞杆。柱塞杆包括具有前端和后端的细长构件，柱塞杆沿着纵向轴线延伸。柱塞杆包括与细长构件的前端相关联的至少一个偏转臂。在将柱塞杆插入塞子期间，偏转臂能够径向向内偏转，并且在插入之后向外偏转到与塞子的内表面接触以将柱塞杆锁定在塞子内。

3. 发明授权

US08475415B2 Positive displacement stopper for a pre-filled syringe 有权
标题翻译：预填充注射器的正位移止动器
公开(公告)号：US08475415B2
公开(公告)日：2013-07-02
申请号：US12133041
申请日：2008-06-04
申请人： Eric Schiller , Michael V. Quinn , Johanna Torres , E Guan , Anthony Economou , Gang Ju
发明人： Eric Schiller , Michael V. Quinn , Johanna Torres , E Guan , Anthony Economou , Gang Ju
IPC分类号： A61M5/315
CPC分类号： A61M5/31513 , A61M5/31511 , A61M5/31515 , A61M2005/31521 , A61M2005/31523
摘要： A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with said main body adjacent the closed front end. The core member includes a nose portion having a profile adapted to create a positive seal with an outlet opening of such syringe barrel.
摘要翻译：公开了一种用于与注射器筒内使用的柱塞杆连接的塞子。止动器包括限定开口后端和封闭前端的主体。敞开的后端适于容纳柱塞杆的前部前端附接部分。挡块还包括与所述主体一体地形成在与封闭前端相邻的芯部件上。芯构件包括鼻部，其具有适于产生具有这种注射器筒的出口的正密封的轮廓。

4. 发明授权

US08740856B2 Stoppers used in pre-filled syringes 有权
标题翻译：塞子用于预装注射器
公开(公告)号：US08740856B2
公开(公告)日：2014-06-03
申请号：US12754101
申请日：2010-04-05
申请人： Michael Vincent Quinn , Eric Schiller , Gang Ju , E Guan
发明人： Michael Vincent Quinn , Eric Schiller , Gang Ju , E Guan
IPC分类号： A61M5/315
CPC分类号： A61M5/31513 , A61M5/31511 , A61M5/31515 , A61M2005/31521 , A61M2005/31523
摘要： A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with the main body adjacent the closed front end. The core member includes a nose portion having a conical tip configured for entering an outlet opening of the syringe barrel. The closed front end of the stopper has a profile configured to cooperate with an internal surface of the syringe barrel wall to prevent reflux and reduce dead space within the barrel.
摘要翻译：公开了一种用于与注射器筒内使用的柱塞杆连接的塞子。止动器包括限定开口后端和封闭前端的主体。敞开的后端适于容纳柱塞杆的前部前端附接部分。挡块还包括与主体相邻的封闭前端一体地形成的芯构件。核心构件包括具有锥形末端的鼻部部分，其被配置用于进入注射器筒的出口开口。止动器的封闭前端具有构造成与注射器筒壁的内表面配合以防止回流并减小镜筒内的死空间的轮廓。

5. 发明申请

US20110034882A1 Stoppers Used in Pre-filled Syringes 有权
标题翻译：塞子用于预装注射器
公开(公告)号：US20110034882A1
公开(公告)日：2011-02-10
申请号：US12754101
申请日：2010-04-05
申请人： Michael Vincent Quinn , Eric Schiller , Gang Ju , E Guan
发明人： Michael Vincent Quinn , Eric Schiller , Gang Ju , E Guan
IPC分类号： A61M5/315
CPC分类号： A61M5/31513 , A61M5/31511 , A61M5/31515 , A61M2005/31521 , A61M2005/31523
摘要： A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with the main body adjacent the closed front end. The core member includes a nose portion having a conical tip configured for entering an outlet opening of the syringe barrel. The closed front end of the stopper has a profile configured to cooperate with an internal surface of the syringe barrel wall to prevent reflux and reduce dead space within the barrel.
摘要翻译：公开了一种用于与注射器筒内使用的柱塞杆连接的塞子。止动器包括限定开口后端和封闭前端的主体。敞开的后端适于容纳柱塞杆的前部前端附接部分。挡块还包括与主体相邻的封闭前端一体地形成的芯构件。核心构件包括具有锥形末端的鼻部部分，其被配置用于进入注射器筒的出口开口。止动器的封闭前端具有构造成与注射器筒壁的内表面配合以防止回流并减小镜筒内的死空间的轮廓。

6. 发明申请

US20090208923A1 System and method for diagnosing diseases 有权
标题翻译：诊断疾病的系统和方法
公开(公告)号：US20090208923A1
公开(公告)日：2009-08-20
申请号：US12287059
申请日：2008-10-03
申请人： Craig A. Gelfand , Jizu Yi , Gang Ju
发明人： Craig A. Gelfand , Jizu Yi , Gang Ju
IPC分类号： C12Q1/00
CPC分类号： G01N33/68 , G01N33/86 , G01N2333/75
摘要： One aspect of the invention provides a method of diagnosing a disease condition, comprising measuring presence or amount of a targeted protein or a degradation product of said protein in a collected biological sample as a marker for the disease condition. The targeted protein or degradation product is selected for measurement based on a prior identification of a measurable half-life at a predetermined time period, including the time at which said method is conducted, and correlating said measuring with the presence or absence of the disease condition. The targeted protein or degradation product may be identified by selecting a protein known or suspected to be a diagnostic marker for the disease condition, analyzing degradation of the protein in the collected biological sample, and selecting a protein or degradation product that exhibits a measurable half-life at a predetermined period of time. The analyzing may include identifying degradation product(s) of the protein as a function of time, and half-life of the protein and the degradation product(s).
摘要翻译：本发明的一个方面提供了一种诊断疾病状况的方法，包括测定收集的生物样品中所述蛋白质的靶向蛋白质或降解产物的存在或量作为疾病状况的标志物。基于在预定时间段（包括进行所述方法的时间）的可测量的半衰期的先前识别，并将所述测量与存在或不存在疾病状态相关联，选择靶向蛋白质或降解产物进行测量。可以通过选择已知或怀疑是疾病状况的诊断标记物的蛋白质或分解产物来分析靶向蛋白质或降解产物，分析所收集的生物样品中蛋白质的降解，以及选择显示可测量的半衰期的蛋白质或降解产物，寿命在预定的时间。分析可以包括鉴定蛋白质的降解产物作为时间的函数，以及蛋白质和降解产物的半衰期。

7. 发明申请

US20080300551A1 STOPPER AND PLUNGER ROD FOR A PRE-FILLED SYRINGE 有权
标题翻译：用于预先灌装的塞子和塞子
公开(公告)号：US20080300551A1
公开(公告)日：2008-12-04
申请号：US12133076
申请日：2008-06-04
申请人： Eric Schiller , Michael V. Quinn , Johanna Torres , E Guan , Anthony Economou , Gang Ju
发明人： Eric Schiller , Michael V. Quinn , Johanna Torres , E Guan , Anthony Economou , Gang Ju
IPC分类号： A61M5/315
CPC分类号： A61M5/31513 , A61M5/31511 , A61M5/31515 , A61M2005/31521 , A61M2005/31523
摘要： A plunger rod adapted for attachment with a stopper for use with a syringe barrel is disclosed. The plunger rod includes an elongated member having a front end and a back end, the plunger rod extending along a longitudinal axis. The plunger rod includes at least one deflecting arm associated with the front end of the elongated member. The deflecting arm is capable of deflecting radially inward during insertion of the plunger rod into a stopper, and deflecting outward into contact with an inner surface of the stopper after insertion to lock the plunger rod within the stopper.
摘要翻译：公开了一种适用于与注射器筒一起使用的止动件的柱塞杆。柱塞杆包括具有前端和后端的细长构件，柱塞杆沿着纵向轴线延伸。柱塞杆包括与细长构件的前端相关联的至少一个偏转臂。在将柱塞杆插入塞子期间，偏转臂能够径向向内偏转，并且在插入之后向外偏转到与塞子的内表面接触以将柱塞杆锁定在塞子内。

8. 发明授权

US08735085B2 Method for diagnosing diseases using a protein or degradation product based on half-life 有权
标题翻译：基于半衰期使用蛋白质或降解产物诊断疾病的方法
公开(公告)号：US08735085B2
公开(公告)日：2014-05-27
申请号：US12287059
申请日：2008-10-03
申请人： Craig A. Gelfand , Jizu Yi , Gang Ju
发明人： Craig A. Gelfand , Jizu Yi , Gang Ju
IPC分类号： C12Q1/56
CPC分类号： G01N33/68 , G01N33/86 , G01N2333/75
摘要： One aspect of the invention provides a method of diagnosing a disease condition, comprising measuring presence or amount of a targeted protein or a degradation product of said protein in a collected biological sample as a marker for the disease condition. The targeted protein or degradation product is selected for measurement based on a prior identification of a measurable half-life at a predetermined time period, including the time at which said method is conducted, and correlating said measuring with the presence or absence of the disease condition. The targeted protein or degradation product may be identified by selecting a protein known or suspected to be a diagnostic marker for the disease condition, analyzing degradation of the protein in the collected biological sample, and selecting a protein or degradation product that exhibits a measurable half-life at a predetermined period of time. The analyzing may include identifying degradation product(s) of the protein as a function of time, and half-life of the protein and the degradation product(s).
摘要翻译：本发明的一个方面提供了一种诊断疾病状况的方法，包括测定收集的生物样品中所述蛋白质的靶向蛋白质或降解产物的存在或量作为疾病状况的标志物。基于在预定时间段（包括进行所述方法的时间）的可测量的半衰期的先前识别，并将所述测量与存在或不存在疾病状态相关联，选择靶向蛋白质或降解产物进行测量。可以通过选择已知或怀疑是疾病状况的诊断标记物的蛋白质或分解产物来分析靶向蛋白质或降解产物，分析所收集的生物样品中蛋白质的降解，以及选择显示可测量的半衰期的蛋白质或降解产物，寿命在预定的时间。分析可以包括鉴定蛋白质的降解产物作为时间的函数，以及蛋白质和降解产物的半衰期。

9. 发明申请

US20080300550A1 POSITIVE DISPLACEMENT STOPPER FOR A PRE-FILLED SYRINGE 有权
标题翻译：一个预先填充的SYRINGE的积极位移停止
公开(公告)号：US20080300550A1
公开(公告)日：2008-12-04
申请号：US12133041
申请日：2008-06-04
申请人： Eric Schiller , Michael V. Quinn , Johanna Torres , E. Guan , Anthony Economou , Gang Ju
发明人： Eric Schiller , Michael V. Quinn , Johanna Torres , E. Guan , Anthony Economou , Gang Ju
IPC分类号： A61M5/315
CPC分类号： A61M5/31513 , A61M5/31511 , A61M5/31515 , A61M2005/31521 , A61M2005/31523
摘要： A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with said main body adjacent the closed front end. The core member includes a nose portion having a profile adapted to create a positive seal with an outlet opening of such syringe barrel.
摘要翻译：公开了一种用于与注射器筒内使用的柱塞杆连接的塞子。止动器包括限定开口后端和封闭前端的主体。敞开的后端适于容纳柱塞杆的前部前端附接部分。挡块还包括与所述主体一体地形成在与封闭前端相邻的芯部件上。芯构件包括鼻部，其具有适于产生具有这种注射器筒的出口的正密封的轮廓。

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