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1. 发明申请

US20110288639A1 Inflatable prostheses and methods of making same 审中-公开
标题翻译：充气假肢及其制作方法
公开(公告)号：US20110288639A1
公开(公告)日：2011-11-24
申请号：US13021523
申请日：2011-02-04
申请人： Nikhil S. Trilokekar , Dimitrios Stroumpoulis , Dustin Leslie , Kaustubh S. Chitre , Nicholas J. Manesis , David J. Schuessler , Thomas E. Powell , James A. Harders
发明人： Nikhil S. Trilokekar , Dimitrios Stroumpoulis , Dustin Leslie , Kaustubh S. Chitre , Nicholas J. Manesis , David J. Schuessler , Thomas E. Powell , James A. Harders
IPC分类号： A61F2/12 , B29C39/10
CPC分类号： A61F2/12 , A61B90/02 , A61F2210/0076 , A61F2250/0003 , A61F2250/0004
摘要： An inflatable tissue expander, suitable for implantation in a breast, is provided. The tissue expander includes a puncturable, self-sealing anterior portion forming a fillable cavity, and posterior portion that is puncture resistant. The anterior portion includes a silicone-based elastomer material having a mesh embedded therein. The posterior portion includes a first composite guard and a second composite guard, each composite guard including an arrangement of puncture resistant members and a flexible substrate having a first side on which the puncture resistant members are disposed in a spaced apart fashion.
摘要翻译：提供了一种适合植入乳房的充气组织扩张器。组织扩张器包括形成可填充空腔的可穿刺的，自密封的前部，以及防刺穿的后部。前部包括具有嵌入其中的网的硅酮基弹性体材料。后部包括第一复合防护件和第二复合防护件，每个复合护罩包括防穿刺构件的布置和具有第一侧面的柔性基底，抗穿刺构件以间隔开的方式设置在该第一侧上。

2. 发明授权

US08636797B2 Inflatable prostheses and methods of making same 有权
标题翻译：充气假肢及其制作方法
公开(公告)号：US08636797B2
公开(公告)日：2014-01-28
申请号：US13105715
申请日：2011-05-11
申请人： Kaustubh S. Chitre , Nicholas J. Manesis , Nikhil S. Trilokekar , Dustin Leslie , David J. Schuessler
发明人： Kaustubh S. Chitre , Nicholas J. Manesis , Nikhil S. Trilokekar , Dustin Leslie , David J. Schuessler
IPC分类号： A61F2/12
CPC分类号： A61F2/12 , A61B90/02 , A61F2210/0076 , A61F2250/0003 , A61F2250/0004
摘要： An inflatable tissue expander or more permanent prosthesis, suitable for implantation in a breast, is provided. The tissue expander includes a puncturable, self-sealing anterior portion forming a fillable cavity, and posterior portion that is puncture resistant. The anterior portion includes a silicone-based elastomer material having a mesh embedded therein. The posterior portion includes a first composite guard and a second composite guard, each composite guard including an arrangement of puncture resistant members and a flexible substrate having a first side on which the puncture resistant members are disposed in a spaced apart fashion.
摘要翻译：提供了一种适合植入乳房的可充气组织扩张器或更多的永久假体。组织扩张器包括形成可填充空腔的可穿刺的，自密封的前部，以及防刺穿的后部。前部包括具有嵌入其中的网的硅酮基弹性体材料。后部包括第一复合防护件和第二复合防护件，每个复合防护罩包括防穿刺构件的布置和具有第一侧面的柔性基底，防穿孔构件以隔开的方式设置在该第一侧上。

3. 发明申请

US20110270391A1 INFLATABLE PROSTHESES AND METHODS OF MAKING SAME 有权
标题翻译：充实的前景和制作方法
公开(公告)号：US20110270391A1
公开(公告)日：2011-11-03
申请号：US13105715
申请日：2011-05-11
申请人： Kaustubh S. Chitre , Nicholas J. Manesis , Nikhil S. Trilokekar , Dustin Leslie , David J. Schuessler
发明人： Kaustubh S. Chitre , Nicholas J. Manesis , Nikhil S. Trilokekar , Dustin Leslie , David J. Schuessler
IPC分类号： A61F2/12
CPC分类号： A61F2/12 , A61B90/02 , A61F2210/0076 , A61F2250/0003 , A61F2250/0004
摘要： An inflatable tissue expander or more permanent prosthesis, suitable for implantation in a breast, is provided. The tissue expander includes a puncturable, self-sealing anterior portion forming a fillable cavity, and posterior portion that is puncture resistant. The anterior portion includes a silicone-based elastomer material having a mesh embedded therein. The posterior portion includes a first composite guard and a second composite guard, each composite guard including an arrangement of puncture resistant members and a flexible substrate having a first side on which the puncture resistant members are disposed in a spaced apart fashion.
摘要翻译：提供了一种适合植入乳房的可充气组织扩张器或更多的永久假体。组织扩张器包括形成可填充空腔的可穿刺的，自密封的前部，以及防刺穿的后部。前部包括具有嵌入其中的网的硅酮基弹性体材料。后部包括第一复合防护件和第二复合防护件，每个复合护罩包括防穿刺构件的布置和具有第一侧面的柔性基底，抗穿刺构件以间隔开的方式设置在该第一侧上。

4. 发明申请

US20120109080A1 PUNCTURE RESISTANT COMPOSITE MATERIALS 审中-公开
标题翻译：耐冲击复合材料
公开(公告)号：US20120109080A1
公开(公告)日：2012-05-03
申请号：US13286767
申请日：2011-11-01
申请人： Nicholas J. Manesis , Kaustubh S. Chitre , Dustin Leslie , Nikhil S. Trilokekar
发明人： Nicholas J. Manesis , Kaustubh S. Chitre , Dustin Leslie , Nikhil S. Trilokekar
IPC分类号： A61M5/00 , B23P17/04
CPC分类号： A61M39/0208 , A61M5/31 , A61M2005/3109 , A61M2039/0226 , Y10T29/49826
摘要： A needle guard assembly includes a first composite guard and a second composite guard, each including an arrangement of puncture resistant members on a flexible substrate. The first composite guard and the second composite guard are positioned such that the arrangement of puncture resistant members of the second composite guard are misaligned with the arrangement of puncture resistant members of the first composite guard. The assembly further includes an intermediate layer disposed between and connecting the first composite guard with the second composite guard.
摘要翻译：针护罩组件包括第一复合防护件和第二复合防护件，每个防护件包括柔性基底上的抗穿刺构件的布置。第一复合防护罩和第二复合护罩被定位成使得第二复合护罩的防穿刺构件的布置与第一复合防护罩的防穿刺构件的布置不一致。组件还包括设置在第一组合防护件与第二复合防护罩之间并将其连接的中间层。

5. 发明申请

US20120123537A1 TISSUE EXPANDER WITH SELF-HEALING ANTERIOR SIDE 审中-公开
标题翻译：组织膨胀机与自我治疗前沿
公开(公告)号：US20120123537A1
公开(公告)日：2012-05-17
申请号：US13291695
申请日：2011-11-08
申请人： Nicholas J. Manesis , Nikhil S. Trilokekar , Dustin Leslie , Kaustubh S. Chitre
发明人： Nicholas J. Manesis , Nikhil S. Trilokekar , Dustin Leslie , Kaustubh S. Chitre
IPC分类号： A61F2/12
CPC分类号： A61M29/02 , A61F2/12
摘要： A tissue expander includes an elastomeric shell having an anterior inside surface and a posterior inside surface with a self-healing layer abutting only a portion of the anterior inside surface. The layer is spaced apart from the posterior inside surface while facilitating folding of the shell prior to insertion into a tissue pocket and also enabling inflation of the shell subsequent to insertion by a fluid injected between the self healing layer and posterior surface.
摘要翻译：组织扩张器包括具有前内表面和后内表面的弹性体外壳，其中自修复层仅邻接前内表面的一部分。该层与后内表面间隔开，同时便于在插入组织袋之前折叠壳体，并且还允许壳体在由自愈合层和后表面之间注入的流体插入之后进行充气。

6. 发明申请

US20130245758A1 INFLATABLE PROSTHESES AND METHODS OF MAKING SAME 审中-公开
标题翻译：充实的前景和制作方法
公开(公告)号：US20130245758A1
公开(公告)日：2013-09-19
申请号：US13612417
申请日：2012-09-12
申请人： Kaustubh S. Chitre , Nicholas J. Manesis , Nikhil Trilokekar , Dustin Leslie , David J. Schuessler
发明人： Kaustubh S. Chitre , Nicholas J. Manesis , Nikhil Trilokekar , Dustin Leslie , David J. Schuessler
IPC分类号： A61F2/12
CPC分类号： A61F2/12 , A61B90/02 , A61F5/0043 , A61F5/0056 , A61F2250/0003 , A61F2250/0004 , A61M5/14212 , A61M39/0208 , A61M2039/0226 , B32B3/08 , B32B25/042 , B32B25/10 , B32B25/20 , B32B2307/581 , B32B2535/00
摘要： An inflatable tissue expander or more permanent prosthesis, suitable for implantation in a breast, is provided.
摘要翻译：提供了一种适合植入乳房的可充气组织扩张器或更多的永久假体。

7. 发明申请

US20110196195A1 IMPLANTABLE SUBCUTANEOUS ACCESS PORT 审中-公开
标题翻译：可伸缩的小型通道
公开(公告)号：US20110196195A1
公开(公告)日：2011-08-11
申请号：US12948703
申请日：2010-11-17
申请人： Joseph S. Raven , Nikhil S. Trilokekar , Kaustubh S. Chitre
发明人： Joseph S. Raven , Nikhil S. Trilokekar , Kaustubh S. Chitre
IPC分类号： A61F2/04
CPC分类号： A61F5/0056 , A61M39/0208 , A61M39/04 , A61M2039/022 , A61M2039/0223 , A61M2039/0226 , A61M2039/0238
摘要： The present invention generally provides a gastric banding system, including an implantable access port having a substantially ellipsoid shape. The access port is pliable and smooth, to increase the comfort of the access port to the patient, and to increase the aesthetic effect of the access port. The ellipsoid shape provides a large needle penetrable surface area for the access port, and enhances the ability of a physician to detect the access port through tactile means. A mesh layer may be incorporated in the housing of the access port, to increase durability of the housing, and to promote the self-sealing properties of the housing.
摘要翻译：本发明通常提供一种胃束带系统，其包括具有基本椭圆形状的可植入进入口。进出口是柔软而平稳的，以增加对病人的进入口的舒适度，并增加入口的美观效果。椭圆形状为入口提供了大的针穿透表面积，并且增强了医师通过触觉手段检测进入口的能力。网状层可以结合在进出口的壳体中，以增加壳体的耐久性，并提高壳体的自密封特性。

8. 发明申请

US20110270022A1 BIOCOMPATIBLE AND BIOSTABLE IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：生物易燃和可生物携带的医疗器械
公开(公告)号：US20110270022A1
公开(公告)日：2011-11-03
申请号：US12887730
申请日：2010-09-22
申请人： Babak Honaryar , Mike Augarten , Marcos Borrell , Kaustubh S. Chitre , Christian Y. Perron , Sean Snow , Erik Torjesen , Nikhil S. Trilokekar , Christopher R. Deuel
发明人： Babak Honaryar , Mike Augarten , Marcos Borrell , Kaustubh S. Chitre , Christian Y. Perron , Sean Snow , Erik Torjesen , Nikhil S. Trilokekar , Christopher R. Deuel
IPC分类号： A61F2/04 , B05D5/00
CPC分类号： A61F5/0059 , A61F2/04 , A61F5/0013 , A61F5/003 , A61F5/0056 , A61M39/0208 , A61M2039/0226 , A61M2039/0238 , A61M2205/215 , A61M2205/583 , A61M2205/82 , A61M2210/1053
摘要： The present invention is related to a biocompatible and biostable implantable medical device. The present invention can include an implantable medical device including an electro-mechanical component. The electro-mechanical component can be coated with various novel and nonobvious coating combinations designed to promote biocompatibility and biostability. One layer of the coating combinations can be a tie layer. Another layer of the coating combinations can be a layer formed on top of the tie layer, and having biocompatible and biostable properties.
摘要翻译：本发明涉及生物相容性和生物稳定的可植入医疗装置。本发明可以包括包括机电组件的可植入医疗装置。机电组件可以涂覆有各种新颖且不透明的涂层组合，旨在促进生物相容性和生物稳定性。一层涂层组合可以是粘结层。涂层组合的另一层可以是在粘结层的顶部上形成的层，并且具有生物相容性和生物稳定性质。

9. 发明申请

US20110306827A1 NEEDLE GUARD TO PROTECT ACCESS PORT TUBING 审中-公开
标题翻译：针头保护接入口管
公开(公告)号：US20110306827A1
公开(公告)日：2011-12-15
申请号：US13178392
申请日：2011-07-07
申请人： Kaustubh S. Chitre , Babak Honaryar , Ahmet Tezel , Nicholas J. Manesis
发明人： Kaustubh S. Chitre , Babak Honaryar , Ahmet Tezel , Nicholas J. Manesis
IPC分类号： A61F2/02
CPC分类号： A61F2/12 , A61B90/02 , A61F5/0043 , A61F5/0056 , A61F2250/0003 , A61F2250/0004
摘要： An inflatable tissue expander, suitable for implantation in a breast, is provided. In addition, a needle guard assembly, suitable to protect tubing leading from an implantable access port, is provided. The needle guard assembly may include a first composite guard and a second composite guard, each composite guard including an arrangement of puncture resistant members and a flexible substrate having a first side on which the puncture resistant members are positioned. The needle guard assembly may comprise a sleeve extending over an end of the tube.
摘要翻译：提供了一种适合植入乳房的充气组织扩张器。此外，还提供了一种适于保护从可植入进入口导出的管的护针组件。针护罩组件可以包括第一复合防护件和第二复合防护件，每个复合防护罩包括防穿刺构件的布置和具有第一侧的柔性基底，防刺构件被定位在其上。针护罩组件可以包括在管的一端延伸的套筒。

10. 发明申请

US20100256651A1 Intraocular Lens Injector with Hydrophilic Coating 审中-公开
标题翻译：具有亲水性涂层的眼内透镜注射器
公开(公告)号：US20100256651A1
公开(公告)日：2010-10-07
申请号：US12754122
申请日：2010-04-05
申请人： Dharmendra Jani , Kaustubh S. Chitre
发明人： Dharmendra Jani , Kaustubh S. Chitre
IPC分类号： A61F9/007 , G02B1/12
CPC分类号： B29C59/16 , A61F2/1664 , B05D3/063 , B05D5/04 , B05D5/08 , B29C59/165 , B29C2035/0827 , B29K2995/0092
摘要： An IOL injector that includes one or more polymeric portions that include a hydrophilic coating component that is effective to facilitate the passage of the IOL through the injector, particularly an injector tip. The IOL injector is prepared by a process that includes irradiating at least a portion of a polymeric, IOL injector with UV light in an environment comprising oxygen to provide a positive percent change in the atomic oxygen content of the polymer material at the surface as determined by X-ray Photoelectron Spectroscopy (XPS). A portion or the entire irradiated portion is then contacted with a solution comprising a hydrophilic coating component. The hydrophilic coating component is selected from a hydrophilic polymer, a hydrophilic copolymer or any one mixture thereof to provide a solution coated portion. The solution coated portion is then heated at a temperature to provide portions of the IOL injector with a shelf-stable, lubricious hydrophilic coating to facilitate delivery of an IOL from the injector.
摘要翻译： IOL注射器，其包括一个或多个聚合物部分，其包括亲水涂层组分，其有效地促进IOL通过注射器，特别是注射器尖端。 IOL注射器通过一种方法制备，该方法包括在包含氧的环境中用UV光照射聚合物IOL注射器的至少一部分，以提供在表面处的聚合物材料的原子氧含量的正百分比变化，如由 X射线光电子能谱（XPS）。然后将一部分或全部照射部分与包含亲水涂层组分的溶液接触。亲水性涂料组分选自亲水性聚合物，亲水性共聚物或其任何混合物，以提供溶液涂布部分。然后将溶液涂覆的部分在一定温度下加热，以使部分IOL注射器具有稳定的，润滑的亲水性涂层，以便于从注射器输送IOL。

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