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1. 发明授权

US08038710B2 Artificial valve prosthesis 有权
标题翻译：人工瓣膜假体
公开(公告)号：US08038710B2
公开(公告)日：2011-10-18
申请号：US11807879
申请日：2007-05-30
申请人： Neal E. Fearnot , Alan R. Leewood , Ram H. Paul, Jr. , Blayne A. Roeder , William D. Voorhees
发明人： Neal E. Fearnot , Alan R. Leewood , Ram H. Paul, Jr. , Blayne A. Roeder , William D. Voorhees
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2220/005 , A61F2220/0058
摘要： A self-expanding or otherwise expandable artificial valve prostheses for deployment within a body passageway, such as a vessel or duct of a patient. The valve prostheses include a support structure having an outer frame, a supporting member and a valve leaflet. The portion of the valve leaflet is supported by the supporting member and is positioned away from the wall of the body passageway when the device is deployed within the body passageway.
摘要翻译：用于展开在身体通道（例如患者的血管或导管）内的自膨胀或其他可膨胀的人造瓣膜假体。瓣膜假体包括具有外框架，支撑构件和瓣膜小叶的支撑结构。瓣膜小叶的部分由支撑构件支撑，并且当装置展开在身体通道内时，其被定位成远离身体通道的壁。

2. 发明授权

US07655033B2 S-shaped stent design 有权
标题翻译： S形支架设计
公开(公告)号：US07655033B2
公开(公告)日：2010-02-02
申请号：US11297913
申请日：2005-12-08
申请人： Neal E. Fearnot , Blayne A. Roeder , Alan R. Leewood , Jichao Sun
发明人： Neal E. Fearnot , Blayne A. Roeder , Alan R. Leewood , Jichao Sun
IPC分类号： A61F2/06
CPC分类号： A61F2/82 , A61F2/91 , A61F2250/0037 , A61F2250/0039
摘要： A variable curvature stent limb is disclosed herein. A stent derived from a plurality of these variable curvature stent limbs may be highly compressible, such that it is compatible with a low-profile delivery device. This stent may be useful over a wider range of body vessel diameters and may possess a greater fatigue life, since this stent may provide a more controlled constant radial force.
摘要翻译：本文公开了一种可变曲率支架肢体。衍生自多个这些可变曲率支架肢体的支架可以是高度可压缩的，使得其与低调输送装置兼容。该支架可以在更宽范围的体血管直径上有用，并且可以具有更大的疲劳寿命，因为该支架可以提供更受控制的恒定径向力。

3. 发明申请

US20110160844A1 INTRAVASCULAR DEVICE ATTACHMENT SYSTEM HAVING BIOLOGICAL MATERIAL 审中-公开
标题翻译：具有生物材料的血管内装置附件系统
公开(公告)号：US20110160844A1
公开(公告)日：2011-06-30
申请号：US12863038
申请日：2009-01-16
申请人： Kenneth Haselby , Brian D. Choules , Blayne A. Roeder , Richard B. Sisken , David Eric Orr , James D. Purdy , Steven J. Charlebois , David D. Grewe , Neal E. Fearnot , Alan R. Leewood
发明人： Kenneth Haselby , Brian D. Choules , Blayne A. Roeder , Richard B. Sisken , David Eric Orr , James D. Purdy , Steven J. Charlebois , David D. Grewe , Neal E. Fearnot , Alan R. Leewood
IPC分类号： A61F2/84
CPC分类号： A61M1/125 , A61B5/076 , A61B5/14535 , A61B5/14539 , A61B5/6862 , A61B5/6876 , A61B5/6882 , A61F2/0077 , A61F2/2418 , A61F2/2475 , A61F2/86 , A61F2002/068 , A61F2002/8486 , A61F2220/0016 , A61F2220/0058 , A61F2220/0075 , A61F2230/005 , A61F2230/0071 , A61F2230/008 , A61M1/1006 , A61M1/1008 , A61M1/101 , A61M1/1098 , A61M1/122 , A61M1/3653 , A61M1/3659
摘要： An attachment system for attaching an intravascular device to a vessel wall of a body vessel is disclosed. The attachment system includes an intravascular device and biological attachment material connected to the intravascular device. The biological attachment material is configured to attach the intravascular device to the vessel wall.
摘要翻译：公开了一种用于将血管内装置附接到身体血管的血管壁的附接系统。附着系统包括连接到血管内装置的血管内装置和生物附着材料。生物附着材料构造成将血管内装置附接到血管壁。

4. 发明申请

US20110106115A1 INTRAVASCULAR DEVICE ATTACHMENT SYSTEM HAVING STRUTS 审中-公开
标题翻译：具有结构的血管内装置附件系统
公开(公告)号：US20110106115A1
公开(公告)日：2011-05-05
申请号：US12863034
申请日：2009-01-16
申请人： Kenneth Haselby , Brian D. Choules , Blayne A. Roeder , Richard B. Sisken , David Eric Orr , James D. Purdy , Steven J. Charlesbois , David D. Grewe , Neal E. Fearnot , Alan R. Leewood
发明人： Kenneth Haselby , Brian D. Choules , Blayne A. Roeder , Richard B. Sisken , David Eric Orr , James D. Purdy , Steven J. Charlesbois , David D. Grewe , Neal E. Fearnot , Alan R. Leewood
IPC分类号： A61B17/11
CPC分类号： A61M1/125 , A61B5/076 , A61B5/14535 , A61B5/14539 , A61B5/6862 , A61B5/6876 , A61B5/6882 , A61F2/0077 , A61F2/2418 , A61F2/2475 , A61F2/86 , A61F2002/068 , A61F2002/8486 , A61F2220/0016 , A61F2220/0058 , A61F2220/0075 , A61F2230/005 , A61F2230/0071 , A61F2230/008 , A61M1/1006 , A61M1/1008 , A61M1/101 , A61M1/1098 , A61M1/122 , A61M1/3653 , A61M1/3659
摘要： An attachment system for attaching an intravascular device to a vessel wall of a body vessel is disclosed. The attachment system has an intravascular device having a first end and a second end. The intravascular device defines a longitudinal axis along a length thereof. Several struts are connected to one or more ends of the intravascular device. Each strut is configured to move along a strut path relative to the longitudinal axis between an expanded state for engaging the vessel wall and a collapsed state for delivery or retrieval. Each strut has a free end configured to engage the vessel wall in the expanded state.
摘要翻译：公开了一种用于将血管内装置附接到身体血管的血管壁的附接系统。附接系统具有具有第一端和第二端的血管内装置。血管内装置沿其长度限定纵向轴线。几个支柱连接到血管内装置的一个或多个端部。每个支柱被构造成在用于接合血管壁的膨胀状态和用于输送或取回的折叠状态之间相对于纵向轴线沿着支柱路径移动。每个支柱具有构造成在膨胀状态下接合血管壁的自由端。

5. 发明授权

US09517123B2 Endovascular prosthesis and a method of connecting a structural component and a woven graft material 有权
标题翻译：血管内假体和连接结构部件和编织移植材料的方法
公开(公告)号：US09517123B2
公开(公告)日：2016-12-13
申请号：US12143230
申请日：2008-06-20
申请人： Alan R. Leewood , Blayne A. Roeder , Neal E. Fearnot , Jicaho Sun
发明人： Alan R. Leewood , Blayne A. Roeder , Neal E. Fearnot , Jicaho Sun
IPC分类号： A61F2/07 , A61F2/06 , A61F2/848 , A61F2/89
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/065 , A61F2002/075 , A61F2002/8483 , A61F2002/8486 , A61F2210/0004 , A61F2210/0014 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2250/0014 , A61F2250/0017 , A61F2250/0023
摘要： An endovascular prosthesis that includes a stent and a woven graft material. The stent is connected to the graft material by direct attachment of the stent to the graft material at thermoplastically fused regions of the graft material.
摘要翻译：一种血管内假体，其包括支架和编织移植材料。通过在移植材料的热塑性融合区域处将支架直接附接到移植材料上，支架与移植材料连接。

6. 发明申请

US20110106120A1 INTRAVASCULAR DEVICE ATTACHMENT SYSTEM HAVING TUBULAR EXPANDABLE BODY 审中-公开
标题翻译：具有管状膨胀体的血管内装置附件系统
公开(公告)号：US20110106120A1
公开(公告)日：2011-05-05
申请号：US12863030
申请日：2009-01-16
申请人： Kenneth Haselby , Brian D. Choules , Blayne A. Roeder , Richard B. Sisken , David Eric Orr , James D. Purdy , Steven J. Charlebois , David D. Grewe , Neal E. Fearnot , Alan R. Leewood
发明人： Kenneth Haselby , Brian D. Choules , Blayne A. Roeder , Richard B. Sisken , David Eric Orr , James D. Purdy , Steven J. Charlebois , David D. Grewe , Neal E. Fearnot , Alan R. Leewood
IPC分类号： A61B17/11
CPC分类号： A61M1/125 , A61B5/076 , A61B5/14535 , A61B5/14539 , A61B5/6862 , A61B5/6876 , A61B5/6882 , A61F2/0077 , A61F2/2418 , A61F2/2475 , A61F2/86 , A61F2002/068 , A61F2002/8486 , A61F2220/0016 , A61F2220/0058 , A61F2220/0075 , A61F2230/005 , A61F2230/0071 , A61F2230/008 , A61M1/1006 , A61M1/1008 , A61M1/101 , A61M1/1098 , A61M1/122 , A61M1/3653 , A61M1/3659
摘要： An attachment system for attaching an intravascular device to a vessel wall of a body vessel is disclosed. The attachment system includes a tubular expandable body defining a lumen therethrough. The tubular expandable body is configured to move between an expanded state to contact the body vessel and a collapsed state for delivery or retrieval. The tubular expandable body is configured to contact the vessel wall along the length of the tubular expandable body in the expanded state when deployed in the body vessel. An intravascular device is held to the exterior side of the tubular expandable body and is configured to contact the vessel wall when the tubular expandable body is in the expanded state and the system is deployed within a body vessel.
摘要翻译：公开了一种用于将血管内装置附接到身体血管的血管壁的附接系统。附接系统包括限定通过其中的腔的管状可扩张体。管状可膨胀体构造成在膨胀状态下与身体容器接触并且用于输送或取出的折叠状态。管状可膨胀体构造成当展开在身体容器中时，处于膨胀状态的管状可膨胀体的长度的容器壁接触。血管内装置被保持在管状可膨胀体的外侧，并且构造成当管状可膨胀体处于膨胀状态并且系统部署在体内容器内时与血管壁接触。

7. 发明申请

US20080319530A1 ENDOVASCULAR PROSTHESIS AND A METHOD OF CONNECTING A STRUCTURAL COMPONENT AND A WOVEN GRAFT MATERIAL 有权
标题翻译：结缔组织和花纹材料连接的方法
公开(公告)号：US20080319530A1
公开(公告)日：2008-12-25
申请号：US12143230
申请日：2008-06-20
申请人： Alan R. Leewood , Blayne A. Roeder , Neal E. Fearnot , Jicaho Sun
发明人： Alan R. Leewood , Blayne A. Roeder , Neal E. Fearnot , Jicaho Sun
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/065 , A61F2002/075 , A61F2002/8483 , A61F2002/8486 , A61F2210/0004 , A61F2210/0014 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2250/0014 , A61F2250/0017 , A61F2250/0023
摘要： An endovascular prosthesis that includes a stent and a woven graft material. The stent is connected to the graft material by direct attachment of the stent to the graft material at thermoplastically fused regions of the graft material.
摘要翻译：一种血管内假体，其包括支架和编织移植材料。通过在移植材料的热塑性融合区域处将支架直接附接到移植材料上，支架与移植材料连接。

8. 发明申请

US20080154351A1 Stents With Biodegradable Connectors And Stabilizing Elements 审中-公开
标题翻译：具有可生物降解连接器和稳定元件的支架
公开(公告)号：US20080154351A1
公开(公告)日：2008-06-26
申请号：US11850885
申请日：2007-09-06
申请人： Alan R. Leewood , David D. Grewe , Mark J. Hiatt , Anthony O. Ragheb , William D. Voorhees , Blayne A. Roeder , James D. Purdy
发明人： Alan R. Leewood , David D. Grewe , Mark J. Hiatt , Anthony O. Ragheb , William D. Voorhees , Blayne A. Roeder , James D. Purdy
IPC分类号： A61F2/06 , A61B17/10
CPC分类号： A61F2/86 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2002/825 , A61F2002/826 , A61F2002/91566 , A61F2002/91575 , A61F2002/9511 , A61F2210/0004 , A61F2220/0075 , A61F2250/0031 , A61F2250/0071
摘要： Various stent structures are provided with improved axial and torsional flexibility. One type of stent structure includes multiple segmented stent structures connected to each other by biodegradable interconnectors. A delivery system adapted to delivery the multiple segmented stents is also described. Another type of stent structure includes biodegradable connectors that are incorporated into a framework of non-biodegradable interconnecting members that form the support structure of the stent. The biodegradable connectors in both stent structures degrade or are absorbed after the stent is deployed. Stabilizing elements may be provided to the stent structures to supplement the stiffness of the stent with stability during loading and deployment.
摘要翻译：各种支架结构具有改进的轴向和扭转弹性。一种类型的支架结构包括通过可生物降解的互连器彼此连接的多个分段的支架结构。还描述了适于递送多个分段支架的递送系统。另一种类型的支架结构包括可生物降解的连接器，其被结合到形成支架的支撑结构的不可生物降解的互连构件的框架中。支架结构中的可生物降解的连接器在支架部署后降解或被吸收。可以将稳定元件提供给支架结构，以在加载和展开期间具有稳定性补充支架的刚度。

9. 发明授权

US09180030B2 Low profile non-symmetrical stent 有权
标题翻译：薄型非对称支架
公开(公告)号：US09180030B2
公开(公告)日：2015-11-10
申请号：US12332904
申请日：2008-12-11
申请人： David Brocker , William K. Dierking , Alan R. Leewood , Timothy A. M. Chuter , Blayne A. Roeder , Steven J. Charlebois , Richard A. Swift , Sharath Gopalakrishnamurthy , Matthew S. Huser , Jarin Kratzberg , Erik E. Rasmussen , Bent Oehlenschlaeger , Kim Mogelvang Jensen
发明人： David Brocker , William K. Dierking , Alan R. Leewood , Timothy A. M. Chuter , Blayne A. Roeder , Steven J. Charlebois , Richard A. Swift , Sharath Gopalakrishnamurthy , Matthew S. Huser , Jarin Kratzberg , Erik E. Rasmussen , Bent Oehlenschlaeger , Kim Mogelvang Jensen
IPC分类号： A61F2/06 , A61F2/86 , A61F2/856 , A61F2/915 , A61F2/07 , A61F2/848
CPC分类号： A61F2/07 , A61F2/852 , A61F2/856 , A61F2/86 , A61F2/89 , A61F2/915 , A61F2002/065 , A61F2002/075 , A61F2002/825 , A61F2002/8486 , A61F2002/91516 , A61F2002/91566 , A61F2220/0016 , A61F2220/0075 , A61F2230/0013
摘要： A stent for use in a medical procedure having opposing sets of curved apices, where the curved section of one set of apices has a radius of curvature that is greater than the curved section of the other set of apices. One or more such stents may be attached to a graft material for use in endovascular treatment of, for example, aneurysm, thoracic dissection, or other body vessel condition.
摘要翻译：一种用于医疗过程的支架，其具有相对的一组曲面顶点，其中一组顶点的弯曲部分的曲率半径大于另一组顶点的弯曲部分。一个或多个这样的支架可以附着到移植物材料上，以用于血管内治疗例如动脉瘤，胸部解剖或其它身体血管状态。

10. 发明授权

US08679173B2 Hybrid stent and method of making such a stent 有权
标题翻译：混合支架和制造这种支架的方法
公开(公告)号：US08679173B2
公开(公告)日：2014-03-25
申请号：US13257073
申请日：2010-03-15
申请人： W. Kurt Dierking , Alan R. Leewood , Blayne A. Roeder
发明人： W. Kurt Dierking , Alan R. Leewood , Blayne A. Roeder
IPC分类号： A61F2/82
CPC分类号： A61F2/88 , A61F2/07 , A61F2/89
摘要： A hybrid stent (100) includes at least one resilient ring (105) comprising a superelastic wire (102) formed in a sinusoidal pattern of alternating crests (110) and troughs (115) about a circumference of the ring (105). A plurality of malleable cannula segments (120) overlie the superelastic wire at the crests and troughs. Each of the cannula segments (120) includes a bend (125) and has an inner diameter sized to allow relative motion between the wire (102) and the cannula segment (120). The hybrid stent (100) may also include a plurality of gaps (130), where each gap (130) is defined by a spacing between opposing cannula segments (120). Deformation of the malleable cannula segments (120) dominates a response of the stent to substantially uniform radial forces, and deformation of the resilient ring (105) dominates a response of the stent to radially nonuniform crushing forces.
摘要翻译：混合支架（100）包括至少一个弹性环（105），弹性环包括围绕环（105）的圆周以交替的波峰（110）和槽（115）形成的正弦图案的超弹性线（102）。多个可延展的套管段（120）覆盖在顶部和凹槽处的超弹性线。插管段（120）中的每一个包括弯曲部（125），并具有尺寸设定成允许线（102）和套管段（120）之间的相对运动的内径。混合支架（100）还可以包括多个间隙（130），其中每个间隙（130）由相对的套管段（120）之间的间隔限定。可塑性插管段（120）的变形支配支架基本上均匀的径向力的响应，并且弹性环（105）的变形支配支架对径向不均匀的破碎力的响应。

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