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    • 1. 发明申请
    • Oral Care Compositions With Improved Flavor
    • 具有改善风味的口腔护理组合
    • US20120082628A1
    • 2012-04-05
    • US13248308
    • 2011-09-29
    • John Christian HaughtChristine Marie CahenKoti Tatachar SreekishnaWenzhu ZhaoYakang LinCathy Renee Schinaman
    • John Christian HaughtChristine Marie CahenKoti Tatachar SreekishnaWenzhu ZhaoYakang LinCathy Renee Schinaman
    • A61K8/58A61Q11/00A61K8/60A61K8/37A61K8/49
    • A61K8/37A61Q11/00
    • Oral care compositions having improved taste, said compositions comprising: a carrier material; from about 0.001 to about 10%, by weight of the composition, of an oral care component selected from metal salts, antimicrobial agents, bad breath reduction agents, bleaching agents, surfactants, or a combination thereof; and from about 0.0001 to about 1%, by weight of the composition, of a TRPA1 agonist selected from vanillin esters; benzoate esters; hydroxybenzoate derivatives; methoxy benzoate derivatives; hydroxybutanedioate derivatives; benzamidobenzoate derivatives; methylpropanoate derivatives; phenyl acetate derivatives; hex-3-enoate derivatives; 2-(furan-2-ylmethylsulfanyl)-3-methylpyrazine; phenylmethoxymethylbenzene; (2R)-2-azaniumyl-3-[(2R)-2-azaniumyl-3-oxido-3-oxopropyl]disulfanylpropanoate; (3E)-2-hydroxy-4,8-dimethylnona-3,7-dienal; (2R)-2-azaniumyl-3-[(2S)-2-azaniumyl-3-oxido-3-oxopropyl]disulfanylpropanoate; (3Z)-3-butylidene-2-benzofuran-1-one; 3-methyl-N-(3-methylbutyl)butan-1-imine; 2-(furan-2-ylmethyldisulfanylmethyl)furan; and combinations thereof. Uses thereof and methods of improving the taste of an oral care composition.
    • 具有改善味道的口腔护理组合物,所述组合物包含:载体材料; 约0.001至约10重量%的选自金属盐,抗微生物剂,口臭减少剂,漂白剂,表面活性剂或其组合的口腔护理组分; 和约0.0001至约1重量%的选自香草醛酯的TRPA1激动剂; 苯甲酸酯; 羟基苯甲酸酯衍生物; 甲氧基苯甲酸酯衍生物; 羟基丁二酸衍生物; 苯甲酰胺基苯甲酸酯衍生物; 甲基丙酸酯衍生物; 苯基乙酸酯衍生物; 己烯-3-烯酸衍生物; 2-(呋喃-2-基甲基硫烷基)-3-甲基吡嗪; 苯基甲氧基甲基苯; (2R)-2-氮基-3 - [(2R)-2-氮氧基-3-氧代-3-氧代丙基]二硫代丙酸酯; (3E)-2-羟基-4,8-​​二甲基纳-3,7-二烯醛; (2R)-2-氨基-3 - [(2S)-2-氮丙基-3-氧代丙氧基]二硫代丙酸酯; (3Z)-3-亚丁基-2-苯并呋喃-1-酮; 3-甲基-N-(3-甲基丁基)丁-1-胺; 2-(呋喃-2-基甲基二硫基甲基)呋喃; 及其组合。 其用途和改善口腔护理组合物的味道的方法。