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1. 发明授权

US6132680A Method for sterilizing an interior of an article 有权
标题翻译：消毒制品内部的方法
公开(公告)号：US6132680A
公开(公告)日：2000-10-17
申请号：US394538
申请日：1999-09-10
申请人： Tralance O. Addy , Paul Taylor Jacobs , Szu-Min Lin , Jon Morrell Jacobs
发明人： Tralance O. Addy , Paul Taylor Jacobs , Szu-Min Lin , Jon Morrell Jacobs
IPC分类号： A61L2/00 , A61L2/02 , A61L2/14 , A61L2/16 , A61L2/18 , A61L2/20 , A61L101/22
CPC分类号： A61L2/186 , A61L2/14 , A61L2/16 , A61L2/208 , A61L2202/122 , A61L2202/24 , Y10S220/913 , Y10S422/906
摘要： A method for sterilizing an article in a diffusion restricted container includes placing the article in a diffusion restricted container with at least one communication port, placing the container in a vacuum chamber, introducing a vaporizable germicide into the container, and reducing the pressure in the vacuum chamber, generating germicide vapor and sterilizing the article. The article to be sterilized can be a diffusion restricted device, such as a hinge, a mated surface, or a lumen. The germicide may be peroxide or peracetic acid.
摘要翻译：用于对扩散限制容器中的物品进行灭菌的方法包括将物品放置在具有至少一个连通口的扩散限制容器中，将容器放置在真空室中，将可蒸发的杀菌剂引入容器中，并降低真空中的压力室，产生杀菌蒸气并对物品进行灭菌。待消毒的物品可以是扩散受限装置，例如铰链，配合表面或内腔。杀菌剂可以是过氧化物或过乙酸。

2. 发明授权

US6060019A Plasma-enhanced vacuum drying 失效
标题翻译：等离子增强真空干燥
公开(公告)号：US6060019A
公开(公告)日：2000-05-09
申请号：US838759
申请日：1997-04-09
申请人： Robert M. Spencer , Tralance O. Addy
发明人： Robert M. Spencer , Tralance O. Addy
IPC分类号： A61L2/02 , A61L2/14 , A61L2/20 , F26B5/00 , F26B5/04
CPC分类号： A61L2/208 , A61L2/14 , F26B5/00 , F26B5/048 , A61L2202/24
摘要： A plasma-enhanced vacuum drying method is disclosed. It is advantageously applied in plasma sterilization processes in particular, and represents a significant improvement for general evacuation drying methods. Articles to be sterilized are placed in a sealed chamber and the chamber is evacuated. A plasma of residual gas species is generated in the chamber during an initial evacuation step. This promotes drying of the articles and advantageously allows a desired pressure to be attained more quickly than without the plasma. Sterilizing gas is injected into the chamber, and a second plasma is generated to activate the sterilizing gas plasma, thereby sterilizing the articles in the chamber.
摘要翻译：公开了一种等离子体增强真空干燥方法。尤其适用于等离子体灭菌方法，代表了一般抽真空干燥方法的显着改进。将待灭菌的物品放置在密封的室中，并将室抽真空。在初始抽空步骤期间，在室中产生残余气体种类的等离子体。这促进制品的干燥并且有利地允许比没有等离子体更快地获得所需的压力。将灭菌气体注入到室中，产生第二等离子体以激活灭菌气体等离子体，从而对室中的物品进行灭菌。

3. 发明授权

US4908163A Nonwoven medical fabric 失效
标题翻译：无纺布面料
公开(公告)号：US4908163A
公开(公告)日：1990-03-13
申请号：US884563
申请日：1986-07-11
申请人： Larry H. McAmish , Tralance O. Addy , George F. Lee
发明人： Larry H. McAmish , Tralance O. Addy , George F. Lee
IPC分类号： D04H1/72 , A41D13/12 , A41D31/00 , A61B19/08 , D04H1/56
CPC分类号： D04H1/56 , A61B46/40 , Y10S428/903 , Y10S428/913 , Y10T428/24603 , Y10T428/24802 , Y10T442/625 , Y10T442/68
摘要： A nonreinforced microfiber fabric is disclosed. The fabric has minimum grab tensile strength to weight ratio greater than 0.8 N per gram per square meter and a minimum Elmendorf tear strength to weight ratio greater than 0.04 N per gram per square meter. The fibers in the fabric have an average length greater than 10 centimeters and at least 80% of the fibers have a diameter of 7 microns or less. The fabric is made by thermally embossing a microfiber web which is made with a minimum of degradation to the polymer and employing high velocity secondary air to maintain air flow uniformity and fiber length.
摘要翻译：公开了一种非增强的超细纤维织物。织物具有最小的拉伸强度与重量比大于0.8N /克/平方米，最小埃尔曼多夫撕裂强度与重量比大于0.04N /克/平方米。织物中的纤维具有大于10厘米的平均长度，并且至少80％的纤维具有7微米或更小的直径。该织物是通过热压花制的超细纤维网制成的，该纤维网以最低的聚合物降解制成，并采用高速二次空气来保持气流均匀性和纤维长度。

4. 发明授权

US4118832A Method for minimizing the accumulation of static charges on fibers resulting from fiberization of pulp lap sheets 失效
标题翻译：用于最小化由纸浆搭接片纤维化引起的纤维上的静电荷积聚的方法
公开(公告)号：US4118832A
公开(公告)日：1978-10-10
申请号：US722478
申请日：1976-09-13
申请人： Tralance O. Addy , David P. Gutman
发明人： Tralance O. Addy , David P. Gutman
IPC分类号： D04H1/00 , D04H1/732
CPC分类号： D04H1/732 , D21B1/066
摘要： A method for minimizing the accumulation of static charges on fibers resulting from the dry-fiberization of pulp lap sheets includes the steps of: (1) directing a plurality of the pulp lap sheets into a stacked condition; (2) directing the stack of sheets in a downstream direction to a fiberizing device for separating the fibers from the stack; and (3) applying an antistatic chemical to less than all of the sheets in the stack upstream of the fiberizing device.
摘要翻译：用于最小化由纸浆搭接片的干纤维化引起的纤维上的静电荷的累积的方法包括以下步骤：（1）将多个纸浆搭接片引导到堆叠状态; （2）沿下游方向将片材堆叠引导到纤维化装置，用于将纤维从堆叠中分离; 和（3）将抗静电化学品施加到小于在纤维化装置上游的堆叠中的所有片材。

5. 发明授权

US07250619B2 Powered sterile solution device 失效
标题翻译：电源无菌溶液装置
公开(公告)号：US07250619B2
公开(公告)日：2007-07-31
申请号：US10478908
申请日：2002-05-14
申请人： Michael A. Taylor , Mark L. Sizelove , Tralance O. Addy
发明人： Michael A. Taylor , Mark L. Sizelove , Tralance O. Addy
IPC分类号： B01D61/08
CPC分类号： B01D61/145 , A61M1/1656 , A61M1/1666 , A61M1/1672 , A61M1/1674 , A61M1/287 , B01D61/147 , B01D61/18 , C02F1/444
摘要： The disclosure below relates to apparatus and methods for producing medicament using sub-optimal water sources. One embodiment of the disclosure is directed to an apparatus comprising a preliminary purification component, a disinfection component, a pharmaceutical grade water preparation (PGW) component, and a drug pack. Another disclosed embodiment relates to a method for producing a peritoneal dialysis solution, comprising, passing diluent through a preliminary purification component, passing diluent through a disinfection component, passing diluent through a PGW preparation component, passing diluent through a drug pack, and collecting solute produced by the drug pack.
摘要翻译：下面的公开涉及使用次优水源生产药物的装置和方法。本公开的一个实施方案涉及包含初步净化组分，消毒组分，药物级水制剂（PGW）组分和药物组合的装置。另一个公开的实施方案涉及一种生产腹膜透析溶液的方法，其包括使稀释剂通过预净化组分，使稀释剂通过消毒组分，使稀释剂通过PGW制备组分，使稀释剂通过药物包装，并收集产生的溶质由药包。

6. 发明授权

US06495100B1 Method for sterilizing devices in a container 失效
标题翻译：对容器中的装置进行消毒的方法
公开(公告)号：US06495100B1
公开(公告)日：2002-12-17
申请号：US09470244
申请日：1999-12-22
申请人： Szu-Min Lin , Anthony Lemus , Harold R. Williams , Paul Taylor Jacobs , Tralance O. Addy , Jon Morrell Jacobs
发明人： Szu-Min Lin , Anthony Lemus , Harold R. Williams , Paul Taylor Jacobs , Tralance O. Addy , Jon Morrell Jacobs
IPC分类号： A61L220
CPC分类号： A61L2/208 , A61L2/14 , A61L2/16 , A61L2202/122 , A61L2202/14 , A61L2202/24
摘要： A method for sterilizing medical devices and similar instruments in diffusion-restricted containers is provided. The sterilization method includes placing a liquid solution containing vaporizable germicide such as hydrogen peroxide into the diffusion-restricted container and vaporizing the germicide. The containers can be attachable and detachable to a sterilization system, and used as a vacuum chamber. An attachable/detachable container containing an article to be sterilized can be nested with a second container, and the article and inside and outside of the inner container are sterilized. The sterile article inside the nested containers can be transported and the sterile inner container with the sterilized article can removed from the outer container and placed in a sterile environment without contaminating the sterile environment. The sterile article can then be removed from the sterile container and utilized. Alternatively, the sterilization method may include introducing germicide vapor into an attachable/detachable container.
摘要翻译：提供了一种在扩散限制容器中对医疗器械和类似仪器进行消毒的方法。灭菌方法包括将含有可蒸发的杀菌剂如过氧化氢的液体溶液放置在扩散限制容器中并使杀菌剂蒸发。容器可以安装和拆卸到灭菌系统，并用作真空室。容纳待灭菌物品的可装卸的容器可以嵌入第二容器，并且将内部容器的内部和外部消毒。嵌套容器内的无菌制品可以运输，具有灭菌制品的无菌内容器可以从外容器中取出并放置在无菌环境中，而不会污染无菌环境。然后将无菌制品从无菌容器中取出并使用。或者，灭菌方法可以包括将杀菌剂蒸气引入可附接/可拆卸的容器中。

7. 发明授权

US6068817A Method for sterilizing an interior of an article 失效
标题翻译：消毒制品内部的方法
公开(公告)号：US6068817A
公开(公告)日：2000-05-30
申请号：US105280
申请日：1998-06-26
申请人： Tralance O. Addy , Paul Taylor Jacobs , Szu-Min Lin , Jon Morrell Jacobs
发明人： Tralance O. Addy , Paul Taylor Jacobs , Szu-Min Lin , Jon Morrell Jacobs
IPC分类号： A61L2/00 , A61L2/02 , A61L2/14 , A61L2/16 , A61L2/18 , A61L2/20 , A61L101/22
CPC分类号： A61L2/186 , A61L2/14 , A61L2/16 , A61L2/208 , A61L2202/122 , A61L2202/24 , Y10S220/913 , Y10S422/906
摘要： A method for sterilizing an interior of an article with a diffusion-restricted area therein includes the steps of contacting the interior of the diffusion-restricted area with a source of peroxide, and exposing the device to negative pressure for a time period sufficient to effect complete sterilization of the diffusion-restricted area.
摘要翻译：用于对其中具有扩散限制区域的物品的内部进行灭菌的方法包括使扩散受限区域的内部与过氧化物源接触的步骤，并将该装置暴露于负压以达到足以完成的时间扩散限制区域的灭菌。

8. 发明授权

US5656238A Plasma-enhanced vacuum drying 失效
标题翻译：等离子增强真空干燥
公开(公告)号：US5656238A
公开(公告)日：1997-08-12
申请号：US320932
申请日：1994-10-11
申请人： Robert M. Spencer , Tralance O. Addy
发明人： Robert M. Spencer , Tralance O. Addy
IPC分类号： A61L2/02 , A61L2/14 , A61L2/20 , F26B5/00 , F26B5/04 , A61L2/00 , B01J19/08
CPC分类号： A61L2/208 , A61L2/14 , F26B5/00 , F26B5/048 , A61L2202/24
摘要： A plasma-enhanced vacuum drying method is disclosed. It is advantageously applied in plasma sterilization processes in particular, and represents a significant improvement for general evacuation drying methods. Articles to be sterilized are placed in a sealed chamber and the chamber is evacuated. A plasma of residual gas species is generated in the chamber during an initial evacuation step. This promotes drying of the articles and advantageously allows a desired pressure to be attained more quickly than without the plasma. Sterilizing gas is injected into the chamber, and a second plasma is generated to activate the sterilizing gas plasma, thereby sterilizing the articles in the chamber.
摘要翻译：公开了一种等离子体增强真空干燥方法。尤其适用于等离子体灭菌方法，代表了一般抽真空干燥方法的显着改进。将待灭菌的物品放置在密封的室中，并将室抽真空。在初始抽空步骤期间，在室中产生残余气体种类的等离子体。这促进制品的干燥并且有利地允许比没有等离子体更快地获得所需的压力。将灭菌气体注入到室中，产生第二等离子体以激活灭菌气体等离子体，从而对室中的物品进行灭菌。

9. 发明授权

US06319480B1 Sterilized device in diffusion-restricted container 有权
标题翻译：扩散限制容器中的灭菌装置
公开(公告)号：US06319480B1
公开(公告)日：2001-11-20
申请号：US09643336
申请日：2000-08-22
申请人： Tralance O. Addy , Paul Taylor Jacobs , Szu-Min Lin , Jon Morrell Jacobs
发明人： Tralance O. Addy , Paul Taylor Jacobs , Szu-Min Lin , Jon Morrell Jacobs
IPC分类号： A61L220
CPC分类号： A61L2/186 , A61L2/14 , A61L2/16 , A61L2/208 , A61L2202/122 , A61L2202/24 , Y10S220/913 , Y10S422/906
摘要： A sterilized article is within the interior of a diffusion-restricted container. The container substantially prevents entry of microorganisms into the interior thereof. The container has at least one entry/exit port which permits entry/exit of gas and/or vapor into/out of the interior, but prevents entry of microorganisms into the interior.
摘要翻译：无菌制品在扩散限制容器的内部。容器基本上防止微生物进入其内部。容器具有至少一个入口/出口，其允许气体和/或蒸气进入/离开内部，但是防止微生物进入内部。

10. 发明授权

US6030579A Method of sterilization using pretreatment with hydrogen peroxide 失效
标题翻译：用过氧化氢预处理灭菌方法
公开(公告)号：US6030579A
公开(公告)日：2000-02-29
申请号：US628965
申请日：1996-04-04
申请人： Tralance O. Addy , Paul Taylor Jacobs , Szu-Min Lin , Jon Morrell Jacobs
发明人： Tralance O. Addy , Paul Taylor Jacobs , Szu-Min Lin , Jon Morrell Jacobs
IPC分类号： A61L2/00 , A61L2/02 , A61L2/14 , A61L2/16 , A61L2/18 , A61L2/20 , A61L101/22
CPC分类号： A61L2/186 , A61L2/14 , A61L2/16 , A61L2/208 , A61L2202/122 , A61L2202/24 , Y10S220/913 , Y10S422/906
摘要： A method for hydrogen peroxide vapor sterilization of medical devices and similar instruments having long narrow lumens or diffusion restricted areas includes the step of pretreating the article to be sterilized with a dilute solution of hydrogen peroxide prior to exposure to a vacuum or a vacuum followed by plasma. The method is such that, upon vaporization of the solution caused by the vacuum, the hydrogen peroxide remains in contact with the article for a time sufficient to achieve sterilization.
摘要翻译：用于具有长狭窄管腔或扩散限制区域的医疗装置和类似仪器的过氧化氢蒸气灭菌方法包括在暴露于真空或真空之后用等离子体处理在过氧化氢稀释溶液中待灭菌的制品的步骤。该方法使得当由真空蒸发溶液时，过氧化氢保持与制品接触足以实现灭菌的时间。

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