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1. 发明申请

US20100267834A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR DIFFERENTIALLY ALTERING GENE EXPRESSION TO PROVIDE NEUROPROTECTION FOR THE ANIMAL CENTRAL NERVOUS SYSTEM AGAINST THE EFFECTS OF ISCHEMIA, NEURODEGENERATION, TRAUMA AND METAL POISONING 审中-公开
标题翻译：方法和药物组合物，用于不同程度地改变基因表达，为动物中枢神经系统提供神经保护，防止ISCHEMIA，神经细胞凋亡，TRAUMA和金属毒素的作用
公开(公告)号：US20100267834A1
公开(公告)日：2010-10-21
申请号：US12829844
申请日：2010-07-02
申请人： William H. Frey, II , Samuel Scott Panter , Leah Ranae Bresin Hanson , Annina Roeytenberg
发明人： William H. Frey, II , Samuel Scott Panter , Leah Ranae Bresin Hanson , Annina Roeytenberg
IPC分类号： A61K31/164 , C07C237/06 , A61P25/28
CPC分类号： A61K9/0043 , A61K31/165 , A61K31/195 , A61K38/1841 , A61K38/2006 , A61K38/28 , A61K38/30 , A61K45/06 , A61K2800/522
摘要： Pharmaceutical compositions for treating and/or pre-treating or preconditioning the animal central nervous system against the effects of Alzheimer's Disease including the associated neurodegeneration and cognitive, behavioral and physical impairments. In one embodiment, an effective dose of deferoxamine (DFO) is administered to the upper one-third of the subject patient's nasal cavity to effectively bypass the blood-brain barrier, thereby allowing application of the DFO dose directly to the central nervous system.
摘要翻译：用于治疗和/或预处理或预处理动物中枢神经系统的药物组合物抵抗阿尔茨海默病的影响，包括相关的神经变性和认知，行为和身体损伤。在一个实施方案中，将有效剂量的去铁胺（DFO）施用于受试患者鼻腔的上三分之一，以有效地绕过血脑屏障，从而允许将DFO剂量直接施用于中枢神经系统。

2. 发明申请

US20060227761A1 Phone-based remote media system interaction 有权
公开(公告)号：US20060227761A1
公开(公告)日：2006-10-12
申请号：US11100758
申请日：2005-04-07
申请人： Samuel Scott , John Mick
发明人： Samuel Scott , John Mick
IPC分类号： H04L12/66
CPC分类号： H04L12/2803 , H04L12/2818 , H04M11/007 , H04N7/17318 , H04N21/2393 , H04N21/25875 , H04N21/4753 , H04N21/4788 , H04N21/6187
摘要： Phone-based remote media system interaction is described. A content distribution system provides a telephone-based voice menu system that enables a caller to select a media system control command. The content distribution system then causes the media system control command to be executed in association with a remote media system associated with, or specified by, the caller.

3. 发明申请

US20060117260A1 Grouping of representations in a user interface 审中-公开
标题翻译：在用户界面中对表示进行分组
公开(公告)号：US20060117260A1
公开(公告)日：2006-06-01
申请号：US11000102
申请日：2004-11-30
申请人： David Sloo , Kevin Carle , Michael Cleron , Samuel Scott , Vivek Thukral
发明人： David Sloo , Kevin Carle , Michael Cleron , Samuel Scott , Vivek Thukral
IPC分类号： G06F17/00 , H04N5/44
CPC分类号： H04N21/47211 , H04N7/163 , H04N21/4532 , H04N21/47202 , H04N21/4821
摘要： Grouping of representations in a user interface is described. In an implementation, a method includes distinguishing a plurality of on-demand content items from a plurality of time-dependent content items that are described in data. A plurality of linearly-arranged groupings is formed, based on the distinguishing, for output in a user interface. At least one of the groupings includes representations of time-dependent content items that are available via a particular channel. Another one of the groupings includes representations of on-demand content items that are available via plurality of channels.
摘要翻译：描述用户界面中的表示的分组。在实现中，一种方法包括从数据中描述的多个时间相关内容项区分多个点播内容项目。基于用户界面中的输出，形成多个线性排列的分组。分组中的至少一个包括通过特定频道可用的时间相关内容项的表示。分组中的另一个包括通过多个频道可用的点播内容项目的表示。

4. 发明申请

US20050210501A1 Method and apparatus for handling metadata 审中-公开
标题翻译：处理元数据的方法和装置
公开(公告)号：US20050210501A1
公开(公告)日：2005-09-22
申请号：US10805031
申请日：2004-03-19
申请人： Daniel Zigmond , Samuel Scott , Kevin Carle
发明人： Daniel Zigmond , Samuel Scott , Kevin Carle
IPC分类号： G06F17/30 , G11B27/10 , G11B27/32 , H04N5/76 , H04N5/765 , H04N5/775 , H04N5/781 , H04N5/782 , H04N5/85 , H04N5/92 , H04N7/025 , H04N7/10 , H04N9/804 , H04N9/82 , H04N7/173
CPC分类号： H04N5/782 , G11B27/105 , G11B27/329 , H04N5/765 , H04N5/775 , H04N5/781 , H04N5/85 , H04N5/907 , H04N9/8042 , H04N9/8205 , H04N21/4334 , H04N21/4586 , H04N21/6581 , H04N21/84
摘要： A system records a video program as well as metadata associated with the video program. The system then receives updated metadata associated with the video program. The previously recorded metadata is replaced with the updated metadata.
摘要翻译：系统记录视频节目以及与视频节目相关联的元数据。然后系统接收与视频节目相关联的更新的元数据。先前记录的元数据将被更新的元数据替换。

5. 发明申请

US20050210138A1 Method and apparatus for managing channel information 有权
标题翻译：用于管理频道信息的方法和装置
公开(公告)号：US20050210138A1
公开(公告)日：2005-09-22
申请号：US10806976
申请日：2004-03-22
申请人： Daniel Zigmond , Vivek Thukral , Samuel Scott
发明人： Daniel Zigmond , Vivek Thukral , Samuel Scott
IPC分类号： G06F15/16 , H04L29/06 , H04N7/24
CPC分类号： H04N21/435 , H04L29/06027 , H04L65/4092 , H04N21/235 , H04N21/2362 , H04N21/4383 , H04N21/6547
摘要： A request for content associated with a particular channel is received from a client device. A system identifies service information data associated with the channel. The system then determines how content associated with the channel will be provided to the client device. Instructions are sent to the client device that notify the client device how to access content associated with the channel.
摘要翻译：从客户端设备接收到与特定频道相关联的内容的请求。系统识别与该信道相关联的服务信息数据。系统然后确定如何将与频道相关联的内容提供给客户端设备。将指令发送到客户端设备，通知客户端设备如何访问与通道相关的内容。

6. 发明申请

US20220119047A1 Single Point Hitch Bed System 有权
公开(公告)号：US20220119047A1
公开(公告)日：2022-04-21
申请号：US17502655
申请日：2021-10-15
申请人： Samuel Scott Wheeler, II
发明人： Samuel Scott Wheeler, II
IPC分类号： B62D53/08
摘要： A single point hitch bed system includes a base frame mounted on a truck bed, the base frame having a front end positioned towards the front of the truck, a rear end opposite the front end, and lateral side ends; a stationary upper deck permanently attached above the base frame; and an extendable lower deck positioned between the stationary upper deck and base frame, wherein the extendable lower deck is mounted via a rail system that allows the extendable lower deck to be extended to an adjustable length. An access hole is positioned towards the front of the stationary upper deck to allow access to a single point hitch that may be permanently secured to the truck. The single point hitch may receive removable components for securing cargo or towed apparatus to the truck. Auxiliary anchor points are positioned atop the base frame, laterally to the stationary upper deck.

7. 发明申请

US20180049508A1 COLLAPSIBLE HELMET 审中-公开
公开(公告)号：US20180049508A1
公开(公告)日：2018-02-22
申请号：US15556748
申请日：2016-03-11
申请人： Samuel Scott Terry
发明人： Samuel Scott Terry
IPC分类号： A42B3/32 , A42B3/06 , A42B3/08 , A42B3/28
CPC分类号： A42B3/322 , A42B3/066 , A42B3/08 , A42B3/283
摘要： A collapsible helmet for cyclists, the collapsible helmet comprising: at least one elongate, curved central portion adapted to extend over a crown of a user's head from front to back; and, a plurality of side portions supported either side of the at least one central portion, the plurality of side portions configured to nest substantially under the at least one central portion when in a collapsed position, and the plurality of side portions configured to form a helmet when in an operative position; and, at least one flexible strap interconnecting the plurality of side portions and the at least one central portion, wherein the at least one flexible strap limits the relative separation of the plurality of side portions in the operative position.

8. 发明授权

US07776312B2 Method of treating Alzheimer's disease comprising administering deferoxamine (DFO) to the upper one-third of the nasal cavity 有权
标题翻译：治疗阿尔茨海默氏病的方法包括将去铁胺（DFO）施用于鼻腔上三分之一
公开(公告)号：US07776312B2
公开(公告)日：2010-08-17
申请号：US11580366
申请日：2006-10-13
申请人： William H. Frey, II , Samuel Scott Panter , Leah Ranae Bresin Hanson , Annina Roeytenberg
发明人： William H. Frey, II , Samuel Scott Panter , Leah Ranae Bresin Hanson , Annina Roeytenberg
IPC分类号： A61K49/00 , A01K31/00 , A01K9/00
CPC分类号： A61K9/0043 , A61K31/165 , A61K31/195 , A61K38/1841 , A61K38/2006 , A61K38/28 , A61K38/30 , A61K45/06 , A61K2800/522
摘要： Methods and pharmaceutical compositions for preconditioning and/or providing neuroprotection to the animal central nervous system against the effects of neurological disorders involving ischemia, trauma, metal poisoning and neurodegeneration, including the associated cognitive, behavioral and physical impairments. In one embodiment, the method is accomplished by stimulating and/or stabilizing hypoxia-inducible factor-1α (HIF-1α). HIF-1α is known to provide a neuroprotective benefit under ischemic conditions. In another embodiment, the method is accomplished by differentially reducing, inhibiting or preventing the increased expression of selected genes caused by neurological disorders. Patients at risk for certain diseases or disorders that are associated with risk for cerebral ischemia may benefit, e.g., those at risk for Alzheimer's disease, Parkinson's disease, Wilson's disease, Huntington's disease, thalassemia or stroke, or those patients having head or spinal cord injury. Patients undergoing certain medical procedures that may result in ischemia may also benefit. Initially, the possibility of ischemia or neurodegeneration is recognized. Intranasal therapeutic agents are administered to the upper third of the nasal cavity to bypass the blood-brain barrier and access the central nervous system directly to avoid unwanted and potentially lethal side effects. Therapeutic agents include those substances that interact with iron and/or copper such as iron chelators, copper chelators, and antioxidants. Particular examples of such therapeutic agents are the iron chelators deferoxamine (DFO) and deferasirox. Intranasal administration of DFO is known to stimulate and/or stabilize HIF-1α and provides an efficient and safe method for pre-conditioning the brain to protect against cerebral ischemia.
摘要翻译：用于预处理和/或向动物中枢神经系统提供神经保护作用的方法和/或药物组合物抵抗涉及缺血，创伤，金属中毒和神经变性的神经障碍的影响，包括相关的认知，行为和身体损伤。在一个实施方案中，该方法通过刺激和/或稳定缺氧诱导因子-1α（HIF-1α）来实现。已知HIF-1α在缺血条件下提供神经保护作用。在另一个实施方案中，该方法通过差异性降低，抑制或预防由神经障碍引起的所选基因的表达增加来实现。与某些与脑缺血风险有关的疾病或病症有风险的患者可能会受益，例如阿尔茨海默病，帕金森病，威尔逊氏症，亨廷顿舞蹈病，地中海贫血或中风危险的患者，或患有头部或脊髓损伤的患者。患有可能导致缺血的某些医疗程序的患者也可能受益。最初认识到缺血或神经变性的可能性。将鼻内治疗剂施用于鼻腔的上三分之一以绕过血脑屏障，并直接进入中枢神经系统，以避免不必要的和可能致命的副作用。治疗剂包括与铁和/或铜相互作用的那些物质，例如铁螯合剂，铜螯合剂和抗氧化剂。这些治疗剂的具体实例是铁螯合剂去铁胺（DFO）和去铁素。已知DFO的鼻内给药可以刺激和/或稳定HIF-1α，并提供了一种预防大脑预防脑缺血的有效和安全的方法。

9. 发明申请

US20060167903A1 MediaDescription data structures for carrying descriptive content metadata and content acquisition data in multimedia systems 有权
标题翻译：媒体描述数据结构，用于在多媒体系统中传送描述性内容元数据和内容获取数据
公开(公告)号：US20060167903A1
公开(公告)日：2006-07-27
申请号：US11042480
申请日：2005-01-25
申请人： Geoffrey Smith , Kevin Carle , Michael Cleron , Samuel Scott , Victor Lee
发明人： Geoffrey Smith , Kevin Carle , Michael Cleron , Samuel Scott , Victor Lee
IPC分类号： G06F17/30
CPC分类号： G06F17/30817 , H04L65/602 , H04L67/28 , H04L67/2842
摘要： A MediaDescription data structure that includes both descriptive metadata, such as EPG information, about a multimedia content item and instructions for acquiring the content item is assigned to each multimedia content item in a multimedia system. A MediaDescription data structure is transferable as a token for representing the content item. The acquisition information may also include information about presenting the content item in different view contexts, as well as information about relationships to other pieces of content, and information about how each different version of the content item is to be acquired and displayed. MediaDescription data structure tokens can be used to facilitate digital video recording (DVR) processes, Internet content rendering processes, multimedia search processes, search results aggregating processes, video-on-demand (VOD) processes, pay-per-view processes, and program guide rendering processes.
摘要翻译：包括关于多媒体内容项目的诸如EPG信息的描述性元数据和用于获取内容项目的指令的MediaDescription数据结构被分配给多媒体系统中的每个多媒体内容项目。 MediaDescription数据结构可作为用于表示内容项的令牌转移。获取信息还可以包括关于在不同视图环境中呈现内容项目的信息，以及关于与其他内容片段的关系的信息，以及关于如何获取和显示内容项目的每个不同版本的信息。媒体描述数据结构令牌可用于促进数字视频录制（DVR）过程，互联网内容呈现过程，多媒体搜索过程，搜索结果聚合过程，视频点播（VOD）流程，按次付费流程和程序指导渲染过程。

10. 发明申请

US20060098943A1 Content re-lock control 审中-公开
标题翻译：内容重新锁定控制
公开(公告)号：US20060098943A1
公开(公告)日：2006-05-11
申请号：US10982551
申请日：2004-11-05
申请人： Samuel Scott , Kevin Carle , Elizabeth McEnroe , Qing Guo , Ann Chapman
发明人： Samuel Scott , Kevin Carle , Elizabeth McEnroe , Qing Guo , Ann Chapman
IPC分类号： H04N5/783 , H04N5/781
CPC分类号： H04N21/443 , H04N21/4147 , H04N21/4532 , H04N21/4753
摘要： Content re-lock control is described. In an embodiment, restricted content is unlocked such that the restricted content can be rendered for a rendering duration. A user-selectable input is received that time-shifts the rendering duration of the restricted content, and an effective rendering duration of the restricted content can be determined from the rendering duration and a time-shift duration that corresponds to the time-shift.
摘要翻译：描述内容重新锁定控制。在一个实施例中，限制内容被解锁，使得受限内容可以渲染呈现持续时间。接收用户可选择的输入，其对所述受限内容的呈现持续时间进行时间偏移，并且可以根据对应于时移的呈现持续时间和时移持续时间来确定受限内容的有效渲染持续时间。

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