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1. 发明申请

US20060206961A1 Use of genes for increasing the oil content in plants 审中-公开
标题翻译：使用基因增加植物油含量
公开(公告)号：US20060206961A1
公开(公告)日：2006-09-14
申请号：US10553303
申请日：2004-04-13
申请人： Petra Cirpus , Oliver Oswald , Hans Ronne , Anders Dahlqvist , Marit Lenman , Andrea Neal , Ulf Stahl , Tao Liu , Antoni Banas , Eva Wiberg
发明人： Petra Cirpus , Oliver Oswald , Hans Ronne , Anders Dahlqvist , Marit Lenman , Andrea Neal , Ulf Stahl , Tao Liu , Antoni Banas , Eva Wiberg
IPC分类号： A01H1/00 , C12N15/82
CPC分类号： C12N9/1029 , C12N15/8247 , C12P7/6409 , C12P7/6463
摘要： The invention relates to methods for increasing the oil content in plants, preferably in plant seeds, by expressing the Ypr140w polypeptide from yeast or corresponding polypeptides from plants. The invention furthermore relates to expression constructs for expressing the yeast polypeptide Ypr140w or corresponding polypeptides from plants in plants, preferably in plant seeds, the transgenic plants expressing the polypeptide and to the use of said transgenic plants for the production of food, feed, seed, pharmaceuticals or fine chemicals, in particular for the production of oils.
摘要翻译：本发明涉及通过从酵母中表达Ypr140w多肽或来自植物的相应多肽来增加植物中油含量的方法，优选在植物种子中。本发明还涉及用于从植物，优选植物种子，表达多肽的转基因植物以及所述转基因植物用于生产食物，饲料，种子，植物的植物中表达酵母多肽Ypr140w或相应多肽的表达构建体。药物或精细化学品，特别是用于生产油。

2. 发明授权

US06791008B1 Use of a class of enzymes and their encoding genes to increase the oil content in transgenic organisms 失效
标题翻译：使用一类酶及其编码基因来增加转基因生物中的油分含量
公开(公告)号：US06791008B1
公开(公告)日：2004-09-14
申请号：US09709457
申请日：2000-11-13
申请人： Antoni Banas , Line Sandager , Ulf Ståhl , Anders Dahlqvist , Marit Lenman , Hans Ronne , Sten Stymne
发明人： Antoni Banas , Line Sandager , Ulf Ståhl , Anders Dahlqvist , Marit Lenman , Hans Ronne , Sten Stymne
IPC分类号： A01H500
CPC分类号： A23D9/00 , A23D9/02 , C11B1/00 , C12N9/1029 , C12N15/8247 , C12P7/6463
摘要： The present invention relates to the use of a novel enzyme and its encoding gene for transformation. More specifically, the invention relates to the use of a gene encoding an enzyme with acyl-CoA:diacylglycerol acyltransferase activity. This gene expressed alone in transgenic organisms will increase the total amount of oil (i.e. triacylglycerols) that is produced.
摘要翻译：本发明涉及新型酶及其编码基因用于转化的用途。更具体地，本发明涉及编码具有酰基-CoA：二酰基甘油酰基转移酶活性的酶的基因的用途。转基因生物中单独表达的该基因将增加所产生的油（即三酰基甘油）的总量。

3. 发明授权

US09681669B2 Plant extracts comprising at least a phenolic compound, for inducing the natural defense of a plant against a pathogen, such as Phytophthora infestans 有权
公开(公告)号：US09681669B2
公开(公告)日：2017-06-20
申请号：US14426837
申请日：2013-09-10
申请人： Erik Andreasson , Marit Lenman
发明人： Erik Andreasson , Marit Lenman , Laith Moushib
IPC分类号： A01N65/08 , A01N37/40 , A01N43/16 , C13B20/06 , C05G3/00 , C05D9/02 , C05F11/10
CPC分类号： A01N65/08 , A01N37/40 , A01N43/16 , C05D9/02 , C05G3/00 , C13B20/06 , Y02E50/343 , Y02W30/47 , C05F11/10 , C05G3/02
摘要： A sugar beet extract (SBE) induced defense in potato plants under green-house conditions and in field trial, without apparent toxicity for the plant. Treatment with SBE resulted in significant reduction of the size of Phytophthora infestans infection lesions and lower sporangia production. SBE had no apparent toxic effect, neither on the hyphal growth of the pathogennor on the germination of sporangia. SBE triggered PR-1 protein induction which suggests that the defense mechanism conferred by SBE could be via direct induced resistance. An array of phenolic metabolites and minerals was found in the SBE and constitutes potential inducers of the defense.

4. 发明申请

US20150245620A1 PLANT EXTRACTS COMPRISING AT LEAST A PHENOLIC COMPOUND, FOR INDUCING THE NATURAL DEFENCE OF A PLANT AGAINST A PATHOGEN, SUCH AS PHYTOPHTHORA INFESTANS 有权
标题翻译：植物提取物包含至少一种酚醛化合物，用于诱导植物对病原体的天然防御，如作为植物病原体
公开(公告)号：US20150245620A1
公开(公告)日：2015-09-03
申请号：US14426837
申请日：2013-09-10
申请人： Erik Andreasson , Marit Lenman
发明人： Erik Andreasson , Marit Lenman , Laith Moushib
IPC分类号： A01N65/08 , C05G3/00
CPC分类号： A01N65/08 , A01N37/40 , A01N43/16 , C05D9/02 , C05G3/00 , C13B20/06 , Y02E50/343 , Y02W30/47 , C05F11/10 , C05G3/02
摘要： A sugar beet extract (SBE) induced defense in potato plants under green-house conditions and in field trial, without apparent toxicity for the plant. Treatment with SBE resulted in significant reduction of the size of Phytophthora infestans infection lesions and lower sporangia production. SBE had no apparent toxic effect, neither on the hyphal growth of the pathogennor on the germination of sporangia. SBE triggered PR-1 protein induction which suggests that the defense mechanism conferred by SBE could be via direct induced resistance. An array of phenolic metabolites and minerals was found in the SBE and constitutes potential inducers of the defense.
摘要翻译：甜菜提取物（SBE）在温室条件下和田间试验中诱导马铃薯植物的防御，对植物没有明显的毒性。用SBE处理导致致病疫霉感染病灶的大小显着减少，并减少孢子囊的产生。 SBE没有明显的毒性作用，也不是病原体菌丝生长对孢子囊发芽的影响。 SBE引发PR-1蛋白诱导，表明SBE赋予的防御机制可以通过直接诱导抗性。在SBE中发现了一系列酚类代谢物和矿物质，构成了防御的潜在诱导剂。

5. 发明公开

US20240110198A1 METHOD OF PROVIDING BROAD-SPECTRUM RESISTANCE TO PLANTS, AND PLANTS THUS OBTAINED 审中-公开
公开(公告)号：US20240110198A1
公开(公告)日：2024-04-04
申请号：US18263146
申请日：2021-12-30
申请人： Erik ANDREASSON , Marit LENMAN , Muhammad Awais ZAHID , Nam PHUONG KIEU , Naga Charan KONAKALLA
发明人： Erik ANDREASSON , Marit LENMAN , Muhammad Awais ZAHID , Nam PHUONG KIEU , Naga Charan KONAKALLA , Svante RESJÖ , Ramesh VETUKURI
IPC分类号： C12N15/82 , C12N9/22
CPC分类号： C12N15/8279 , C12N9/22 , C12N15/8273 , C12N2310/20
摘要： A method of obtaining a plant cell having increased pathogen resistance and/or abiotic stress tolerance is provided, the method comprising the steps of a) providing a plant cell, and b) modifying the genome of the plant cell so as to obtain a decreased or inactivated expression of a protein having an amino acid sequence in which at least one part of the amino acid sequence has at least 78%, such as at least 85%, more preferably at least 90% sequence identity to SEQ ID NO: 5, and wherein the protein comprises less than 200 amino acids. A method of obtaining a plant, as well as a plant cell and a plant, are also provided.

6. 发明授权

US07589253B2 Fatty acid epoxygenase genes from plants and uses therefor in modifying fatty acid metabolism 有权
标题翻译：来自植物的脂肪酸环氧化酶基因，用于修饰脂肪酸代谢
公开(公告)号：US07589253B2
公开(公告)日：2009-09-15
申请号：US09981124
申请日：2001-10-17
申请人： Allan Green , Surinder Singh , Marit Lenman , Sten Stymne
发明人： Allan Green , Surinder Singh , Marit Lenman , Sten Stymne
IPC分类号： C12N15/82 , A01H5/00
CPC分类号： C12N9/0071 , C12N9/0004 , C12N15/8247 , C12P7/6409 , C12P7/6427 , C12P7/6472
摘要： The present invention relates generally to novel genetic sequences that encode fatty acid epoxygenase enzymes, in particular fatty acid Δ12-epoxygenase enzymes from plants that are mixed function monooxygenase enzymes. More particularly, the present invention exemplifies cDNA sequences from Crepis spp. and Vernonia galamensis that encode fatty acid Δ12-epoxygenases. The genetic sequences of the present invention provide the means by which fatty acid metabolism may be altered or manipulated in organisms, such as, for example, yeasts, moulds, bacteria, insects, birds, mammals and plants, and more particularly in plants. The invention also extends to genetically modified oil-accumulating organisms transformed with the subject genetic sequences and to the oils derived therefrom. The oils thus produced provide the means for the cost-effective raw materials for use in the efficient production of coatings, resins, glues, plastics, surfactants and lubricants.
摘要翻译：本发明一般涉及编码脂肪酸环氧化酶的新型遗传序列，特别是来自作为混合功能单加氧酶的植物的脂肪酸Delta12-环氧化酶。更具体地，本发明举例说明了来自Crepis spp的cDNA序列。和Vernonia galamensis，编码脂肪酸Delta12-环氧化酶。本发明的遗传序列提供了在生物体例如酵母，霉菌，细菌，昆虫，鸟类，哺乳动物和植物中，更具体地在植物中可以改变或操纵脂肪酸代谢的方法。本发明还延伸到用受试者遗传序列转化的转基因油积聚生物和由其衍生的油。因此生产的油为用于有效生产涂料，树脂，胶水，塑料，表面活性剂和润滑剂的成本效益好的原材料提供了手段。

7. 发明申请

US20080160592A1 Class of enzymes in the biosynthetic pathway for the production of triacylglycerol and recombinant DNA molecules encoding these enzymes 失效
标题翻译：用于生产三酰基甘油的生物合成途径中的酶类和编码这些酶的重组DNA分子
公开(公告)号：US20080160592A1
公开(公告)日：2008-07-03
申请号：US11679791
申请日：2007-02-27
申请人： Anders Dahlqvist , Ulf Stahl , Marit Lenman , Antoni Banas , Hans Ronne , Sten Stymne
发明人： Anders Dahlqvist , Ulf Stahl , Marit Lenman , Antoni Banas , Hans Ronne , Sten Stymne
IPC分类号： C12P7/64
CPC分类号： C12N9/1029 , A01K2217/05
摘要： The present invention relates to the isolation, identification and characterization of nucleotide sequences encoding an enzyme catalysing the transfer of fatty acids from phospholipids to diacylglycerol in the biosynthetic pathway for the production of triacylglycerol, to the said enzymes and a process for the production of triacylglycerols.
摘要翻译：本发明涉及编码催化脂肪酸从磷脂向二酰基甘油转移到生产三酰基甘油的生物合成途径中的酶的所述酶的编码酶的核苷酸序列的分离，鉴定和表征以及三酰基甘油的制备方法。

8. 发明授权

US06329518B1 Plant fatty acid epoxygenase genes and uses therefor 失效
标题翻译：植物脂肪酸环氧化酶基因及其用途
公开(公告)号：US06329518B1
公开(公告)日：2001-12-11
申请号：US09059769
申请日：1998-04-14
申请人： Allan Green , Surinder Singh , Marit Lenman , Sten Stymne
发明人： Allan Green , Surinder Singh , Marit Lenman , Sten Stymne
IPC分类号： C12N1582
CPC分类号： C12N9/0071 , C12N9/0004 , C12N15/8247 , C12P7/6409 , C12P7/6463
摘要： The present invention relates generally to novel genetic sequences which encode fatty acid epoxygenase enzymes. In particular, the present invention relates to genetic sequences which encode fatty acid &Dgr;12-epoxygenase enzymes comprising mixed function monooxygenase enzymes. More preferably, the present invention provides cDNA sequences which encode plant fatty acid epoxygenases, in particular the Crepis palaestina &Dgr;12-epoxygenase and homologues, analogues and derivatives thereof. The genetic sequences of the present invention provide the means by which fatty acid metabolism may be altered or manipulated in organisms such as yeasts, moulds, bacteria, insects, birds, mammals and plants, in particular to convert unsaturated fatty acids to epoxygenated fatty acids therein. The invention extends to genetically modified oil-accumulating organisms transformed with the subject genetic sequences and to the oils derived therefrom. The oils thus produced provide the means for the cost-effective raw materials for use in the efficient production of coatings, resins, glues, plastics, surfactants and lubricants, amongst others.
摘要翻译：本发明一般涉及编码脂肪酸环氧化酶的新型遗传序列。特别地，本发明涉及编码包含混合功能单加氧酶的脂肪酸DELTA12-环氧化酶的遗传序列。更优选地，本发明提供编码植物脂肪酸环氧化酶的cDNA序列，特别是Crepis palaestina DELTA12-环氧化酶及其同系物，类似物和衍生物。本发明的遗传序列提供了在诸如酵母，霉菌，细菌，昆虫，鸟类，哺乳动物和植物的生物体中脂肪酸代谢可被改变或操作的手段，特别是将不饱和脂肪酸转化为环氧化脂肪酸。本发明延伸到用受试者遗传序列转化的转基因油积聚生物和由其衍生的油。因此生产的油为用于有效生产涂料，树脂，胶水，塑料，表面活性剂和润滑剂等的成本效益好的原料提供了手段。

9. 发明授权

US07465850B2 Use of a gene for increasing the oil content in plants 失效
标题翻译：使用基因增加植物油含量
公开(公告)号：US07465850B2
公开(公告)日：2008-12-16
申请号：US10519943
申请日：2003-07-03
申请人： Martijn Gipmans , Anders Dahlqvist , Antoni Banas , Ulf Stahl , Eva Wiberg , Marit Lenman , Hans Ronne , Sten Stymne
发明人： Martijn Gipmans , Anders Dahlqvist , Antoni Banas , Ulf Stahl , Eva Wiberg , Marit Lenman , Hans Ronne , Sten Stymne
IPC分类号： C12N15/31 , C12N15/82 , C12N15/63 , C12N5/14 , A01H5/00 , A01H5/10
CPC分类号： C12N15/8247 , C07K14/395
摘要： The invention relates to methods for increasing the oil content in plants, preferably in plant seeds, by expressing a polypeptide from yeast. The invention furthermore relates to expression constructs for expressing the yeast polypeptide in plants, preferably in plant seeds, the transgenic plants expressing the yeast polypeptide and to the use of said transgenic plants for the production of food, feeds, seed, pharmaceuticals or fine chemicals, in particular for the production of oils.
摘要翻译：本发明涉及通过从酵母中表达多肽来增加植物中油含量的方法，优选在植物种子中。本发明还涉及用于在植物，优选在植物种子中表达酵母多肽的表达构建体，表达酵母多肽的转基因植物和所述转基因植物用于生产食品，饲料，种子，药物或精细化学品的用途，特别是用于生产油。

10. 发明授权

US07427593B1 Methods of making triacylglycerol using phospholipid:Diacylglycerol acyltransferase 失效
标题翻译：使用磷脂制备三酰基甘油的方法：二酰基甘油酰基转移酶
公开(公告)号：US07427593B1
公开(公告)日：2008-09-23
申请号：US09537710
申请日：2000-03-30
申请人： Andres Dahlqvist , Ulf Stahl , Marit Lenman , Antoni Banas , Hans Ronne , Sten Stymme
发明人： Andres Dahlqvist , Ulf Stahl , Marit Lenman , Antoni Banas , Hans Ronne , Sten Stymme
IPC分类号： A61K38/00
CPC分类号： C12N9/1029 , A01K2217/05
摘要： The present invention relates to the production of triacylglycerol in a transformed organism or host cell, by means of a nucleotide sequence from S. cerevisiae, whereby said enzyme catalyzes the transfer of fatty acids from phospholipids to diacylglycerol in any acyl-CoA-independent reaction. The transformation of the organism or host cell results in increased oil content.
摘要翻译：本发明涉及通过来自酿酒酵母的核苷酸序列在转化的生物体或宿主细胞中生产三酰基甘油，由此所述酶催化脂肪酸在酰基辅酶A非依赖性反应中从磷脂转移到二酰基甘油。生物体或宿主细胞的转化导致油含量增加。

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