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1. 发明申请

US20180304531A1 SYSTEMS AND METHODS OF MANIPULATING POLYMERS 审中-公开
公开(公告)号：US20180304531A1
公开(公告)日：2018-10-25
申请号：US15912339
申请日：2018-03-05
申请人： Nathan Daniel Gallant , Kyle Joseph Hunter
发明人： Nathan Daniel Gallant , Kyle Joseph Hunter
IPC分类号： B29C64/209 , B33Y10/00 , B33Y30/00 , B33Y40/00 , B33Y50/02 , B29C64/106 , B29C64/393 , B33Y70/00
CPC分类号： B29C64/209 , B29C64/106 , B29C64/393 , B33Y10/00 , B33Y30/00 , B33Y40/00 , B33Y50/02 , B33Y70/00
摘要： Methods and systems are provided for mixing component materials and dispensing a gradient product comprising a continuously varied composition of matter. The method includes delivering, by multiple dispensing devices actuated by a motor, component material to a connector where each of multiple connector inputs receives component material from a respective one of the multiple dispensing devices. The component material is forwarded to a mixing tube connected to a single output of the connector. The mixing tube receives the component material from each of the multiple dispensing devices via the connector and mixes the component material. A dispensing nozzle connected to the mixing tube, receives a continuously varying mixture of materials from the mixing tube and dispenses the continuously varying mixture of materials onto a collection bed to form a gradient product comprising a continuously varying composition of matter. An electronic processor controls the varied composition of matter of the gradient product.

2. 发明申请

US20060046196A1 Adhesion promoting ingredients for on-press developable lithographic printing plate precursors 失效
公开(公告)号：US20060046196A1
公开(公告)日：2006-03-02
申请号：US10931328
申请日：2004-09-01
申请人： Joseph Hunter , Eric Clark , James Mulligan , Saraiya Shashikant , Jianbing Huang
发明人： Joseph Hunter , Eric Clark , James Mulligan , Saraiya Shashikant , Jianbing Huang
IPC分类号： G03C1/76
CPC分类号： B41C1/1008 , B41C1/1016 , B41C2201/04 , B41C2210/04 , B41C2210/08 , B41C2210/22 , B41C2210/24 , B41M5/368 , B41N1/08 , B41N1/14 , G03F7/033 , G03F7/085 , Y10S430/111 , Y10S430/165
摘要： Imageable elements, useful as on press developable lithographic printing plate precursors, are disclosed. The elements comprise an imageable layer over a substrate and an one or more adhesion promoting ingredients. The imageable layer comprises a polymerizable compound and a polymeric binder. The adhesion promoting ingredients are titanium chelate and/or co-polymers of a monomer having a polethylene oxide side chain with a monomer having either an acidic group or an anhydride group that has been ring opened to form an acidic group or groups.

3. 发明申请

US20050060812A1 Azetidinium modified polymers and fabric treatment composition 有权
标题翻译：氮杂环丁烷改性聚合物和织物处理组合物
公开(公告)号：US20050060812A1
公开(公告)日：2005-03-24
申请号：US10501499
申请日：2002-12-10
申请人： Stephen Batchelor , Paul Findlay , Joseph Hunter , Andrew Parker , Stephen Rannard
发明人： Stephen Batchelor , Paul Findlay , Joseph Hunter , Andrew Parker , Stephen Rannard
IPC分类号： C08F8/00 , D06M10/00
CPC分类号： C08F8/02 , C08F2800/10 , C08F2800/20 , C08F8/08 , C08F2220/281 , C08F220/34 , C08F2220/286
摘要： The invention relates to a fabric treatment composition which comprises a self-crosslinking polymer possessing pendant azetidinium groups. A first aspect of the invention comprises an azetidinium functionalised polymer containing primary or secondary amine groups. Cross-linking reactions between the azetidinium group and primary or secondary amine groups does not form quaternary groups and consequently does not result in a charged, cross-linked polymer. This lack of charge is believed to overcome the problems of stain fixing and dye adsorption. A second aspect of the present invention subsists in a azetidinium functionalized polymer of which the monomers comprise: an amino-acrylate and/or amino-alkacrylate monomer, and, optionally, further non-amino acrylate and/or alkacrylate monomer. A third aspect of the present invention provides a textile treatment composition which comprises a azetidinium functionalised polymer in accordance with the first or second aspect of the invention and a textile compatible carrier.
摘要翻译：本发明涉及一种织物处理组合物，其包含具有氮杂吖啶基侧基的自交联聚合物。本发明的第一方面包括含有伯胺基或仲胺基团的氮杂环丁烷官能化聚合物。氮杂环丁烷基与伯胺或仲胺基之间的交联反应不形成季基，因此不会导致带电的交联聚合物。认为这种缺乏电荷可以克服染色剂固定和染料吸附的问题。本发明的第二方面存在于氮杂环丁烷官能化聚合物中，其单体包括：氨基 - 丙烯酸酯和/或氨基 - 丙烯酸烷基酯单体，以及任选的其它非氨基丙烯酸酯和/或丙烯酸烷基酯单体。本发明的第三方面提供一种纺织品处理组合物，其包含根据本发明的第一或第二方面的氮杂环丁烷官能化聚合物和纺织品相容的载体。

4. 发明授权

US1731171A Drill stem 失效
公开(公告)号：US1731171A
公开(公告)日：1929-10-08
申请号：US73787824
申请日：1924-09-15
申请人： JOSEPH HUNTER THATCHER
发明人： PERKINS MILLER JESSE
IPC分类号： E21B17/00
CPC分类号： E21B17/00 , Y10T29/49879

5. 发明授权

US08277782B2 Topical oral care compositions comprising host response modulating agents 有权
标题翻译：包含宿主反应调节剂的局部口腔护理组合物
公开(公告)号：US08277782B2
公开(公告)日：2012-10-02
申请号：US11409850
申请日：2006-04-24
申请人： Matthew Joseph Doyle , Stephen Joseph Hunter-Rinderle , Robert Ernest Singer, Jr.
发明人： Matthew Joseph Doyle , Stephen Joseph Hunter-Rinderle , Robert Ernest Singer, Jr.
IPC分类号： A61K7/16
CPC分类号： A61Q11/00 , A61K8/4946 , A61K8/4973 , A61K31/00 , A61K31/407 , A61K31/4164 , A61K31/426 , A61K31/662 , A61K45/06
摘要： The present invention relates to topical oral care compositions comprising in a pharmaceutically acceptable carrier a safe and effective amount of a host-response modulating agent including one or more of an anti-oxidant and modifier of cell redox status, anti-inflammatory agent, metalloproteinase inhibitor, vitamins and nutrients key to maintenance of a host response balance and inhibitor of activation of NF-kB in combination with one or a mixture of additional oral therapeutic actives selected from antimicrobial/antiplaque agents, biofilm inhibiting agents, antibiotics; analgesics and local anesthetic agents; dentinal desensitizing agents and odor masking agents. The present compositions are effective in treating and preventing bacteria-mediated diseases present in the oral cavity and in mediating host reaction to the presence of pathogenic bacteria in the oral cavity as well as the toxins and endotoxins, inflammatory cytokines and mediators released or prompted by these oral pathogens. By controlling bacteria-mediated diseases and conditions present in the oral cavity and modulating host reaction, spread into the bloodstream and other parts of the body of pathogenic bacteria and associated harmful substances is prevented or minimized.
摘要翻译：本发明涉及在药学上可接受的载体中包含安全有效量的宿主应答调节剂的局部口腔护理组合物，其包括一种或多种抗氧化剂和细胞氧化还原状态的改良剂，抗炎剂，金属蛋白酶抑制剂维生素和营养物质是维持宿主反应平衡和NF-kB活化抑制剂与选自抗微生物/抗牙斑剂，生物膜抑制剂，抗生素的一种或其它口服治疗活性物质混合物的关键。镇痛药和局麻药; 牙质脱敏剂和气味掩蔽剂。本发明的组合物有效地治疗和预防口腔中存在的细菌介导的疾病，并且介导宿主对口腔中病原菌的存在的反应以及由这些释放或促进的毒素和内毒素，炎性细胞因子和介质口腔病原体通过控制口腔中存在的细菌介导的疾病和病症并调节宿主反应，防止或最小化扩散到血液中和致病细菌体内的其它部分和相关的有害物质。

6. 发明申请

US20110306018A1 Methods For Improving Pregnancy Outcomes 审中-公开
标题翻译：改善妊娠结局的方法
公开(公告)号：US20110306018A1
公开(公告)日：2011-12-15
申请号：US13215719
申请日：2011-08-23
申请人： Matthew Jospeh Doyle , Stephen Joseph Hunter-Rinderle , Robert Ernest Singer, JR.
发明人： Matthew Jospeh Doyle , Stephen Joseph Hunter-Rinderle , Robert Ernest Singer, JR.
IPC分类号： A61C17/00 , A61K31/155 , A61P29/00 , A61P11/00 , A61P31/00 , A61P9/00 , A61K31/4425 , A61P43/00
CPC分类号： A61Q11/00 , A61K8/347 , A61K8/416 , A61K8/43 , A61K8/49 , A61K8/4926 , A61K9/006 , A61K31/05 , A61K31/14 , A61K31/155 , A61K31/44 , A61K31/4745 , A61K33/24 , A61K33/30 , A61K33/34 , A61K45/06
摘要： The present invention relates to promoting whole body health in humans and animals by using topical oral compositions comprising a safe and effective amount of an antimicrobial agent in admixture with a pharmaceutically acceptable carrier, said compositions being effective in controlling bacterial-mediated diseases and conditions present in the oral cavity and in inhibiting the spread into the bloodstream of pathogenic oral bacteria, associated bacterial toxins and endotoxins, and resultant inflammatory cytokines and mediators. The present invention also encompasses methods of use of these compositions by topically applying to the oral cavity, a safe and effective amount of an antimicrobial agent to promote and/or enhance whole body health in humans and other animals.
摘要翻译：本发明涉及通过使用包含安全有效量的抗微生物剂与药学上可接受的载体混合的局部口服组合物来促进人和动物的全身健康，所述组合物有效地控制细菌介导的疾病和病症口腔和抑制扩散到病原性口腔细菌，相关细菌毒素和内毒素的血液中，以及产生的炎性细胞因子和介质。本发明还包括通过局部施用于口腔使用这些组合物的方法，一种安全有效量的抗微生物剂以促进和/或增强人和其他动物的全身健康。

7. 发明申请

US20110091971A1 Differentiation of Pluripotent Stem Cells 审中-公开
标题翻译：多能干细胞的分化
公开(公告)号：US20110091971A1
公开(公告)日：2011-04-21
申请号：US12493741
申请日：2009-06-29
申请人： Janet Davis , Jiajian Liu , Gopalan Raghunathan , Michael Joseph Hunter , Jose Pardinas , Judith Ann Connor , Ronald Vernon Swanson , Ellen Chi
发明人： Janet Davis , Jiajian Liu , Gopalan Raghunathan , Michael Joseph Hunter , Jose Pardinas , Judith Ann Connor , Ronald Vernon Swanson , Ellen Chi
IPC分类号： C12N5/0735 , C12N5/071
CPC分类号： C12N5/0603 , C12N5/0606 , C12N2501/16 , C12N2506/02
摘要： The present invention is directed to methods to differentiate pluripotent stem cells. In particular, the present invention is directed to methods and compositions to differentiate pluripotent stem cells into cells expressing markers characteristic of the definitive endoderm lineage. The present invention also provides methods to generate and purify agents capable of differentiating pluripotent stem cells into cells expressing markers characteristic of the definitive endoderm lineage.
摘要翻译：本发明涉及分化多能干细胞的方法。特别地，本发明涉及将多能干细胞分化成表达定形内胚层谱系特征性标志物的细胞的方法和组合物。本发明还提供了产生和纯化能够将多能干细胞分化成表达定形内胚层谱系特征性标志物的细胞的方法。

8. 发明申请

US20100291099A1 NOVEL 27411, 23413, 22438, 23553, 25278, 26212, NARC SC1, NARC 10A, NARC 1, NARC 12, NARC 13, NARC17, NARC 25, NARC 3, NARC 4, NARC 7, NARC 8, NARC 11, NARC 14A, NARC 15, NARC 16, NARC 19, NARC 20, NARC 26, NARC 27, NARC 28, NARC 30, NARC 5, NARC 6, NARC 9, NARC 10C, NARC 8B, NARC 9, NARC2A, NARC 16B, NARC 1C, NARC 1A, NARC 25, 86604 AND 32222 MOLECULES AND USES THEREFOR 审中-公开
标题翻译：新的27411,23413,22438,23553,25278,26212，NARC SC1，NARC 10A，NARC 1，NARC 12，NARC 13，NARC 17，NARC 25，NARC 3，NARC 4，NARC 7，NARC 8，NARC 11，NARC 14A ，NARC 15，NARC 16，NARC 19，NARC 20，NARC 26，NARC 27，NARC 28，NARC 30，NARC 5，NARC 6，NARC 9，NARC 10C，NARC 8B，NARC 9，NARC2A，NARC 16B，NARC 1C ，NARC 1A，NARC 25,86604和32222分子及其用途
公开(公告)号：US20100291099A1
公开(公告)日：2010-11-18
申请号：US12817236
申请日：2010-06-17
申请人： Maria A. Glucksmann , Mark J. Williamson , Fong-Ying Tsai , Laura A. Rudolph-Owen , Rosanna Kapeller-Libermann , Rachel E. Meyers , Lillian Wei-Ming Chiang , John Joseph Hunter
发明人： Maria A. Glucksmann , Mark J. Williamson , Fong-Ying Tsai , Laura A. Rudolph-Owen , Rosanna Kapeller-Libermann , Rachel E. Meyers , Lillian Wei-Ming Chiang , John Joseph Hunter
IPC分类号： A61K39/395 , A61K38/45 , C12Q1/68 , G01N33/53 , C12P21/02 , C12N9/12 , C12N5/10 , C12N1/21 , G01N33/566 , A61K38/17 , A61K31/7088 , C07K14/47 , C07K16/18 , C07H21/04 , A61P35/00 , A61P11/00 , A61P13/08 , A61P1/16 , A61P9/04 , A61P9/10 , A61P25/28 , A61P25/16 , A61P17/00 , A61P35/02
CPC分类号： C12Q1/48 , C12N9/1288 , C12Q1/6883 , C12Q2600/112 , C12Q2600/136 , C12Q2600/158 , C12Y207/08005 , G01N2333/91 , G01N2500/00
摘要： The invention provides isolated nucleic acids molecules and proteins, designated 27411, 23413, 22438, 23553, 25278, 26212, NARC SC1, NARC 20A, NARC 1, NARC 12, NARC 13, NARC17, NARC 25, NARC 3, NARC 4, NARC 7, NARC 8, NARC 11, NARC 14A, NARC 15, NARC 16, NARC 19, NARC 20, NARC 26, NARC 27, NARC 28, NARC 30, NARC 5, NARC 6, NARC 9, NARC 10C, NARC 8B, NARC 9, NARC2A, NARC 16B, NARC 1C, NARC 1A, NARC 25, 86604 and 32222 nucleic acid molecules and proteins. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing said nucleic acid molecules, host cells into which the expression vectors have been introduced, nonhuman transgenic animals in which a said genes have been introduced or disrupted, fusion proteins, antigenic peptides and antibodies to said proteins. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供分离的核酸分子和蛋白质，命名为27411,23413,22438,23553,25278,26212，NARC SC1，NARC 20A，NARC 1，NARC 12，NARC 13，NARC 17，NARC 25，NARC 3，NARC 4，NARC 7，NARC 8，NARC 11，NARC 14A，NARC 15，NARC 16，NARC 19，NARC 20，NARC 26，NARC 27，NARC 28，NARC 30，NARC 5，NARC 6，NARC 9，NARC 10C，NARC 8B， NARC 9，NARC2A，NARC 16B，NARC 1C，NARC 1A，NARC 25，86604和32222核酸分子和蛋白质。本发明还提供了反义核酸分子，含有所述核酸分子的重组表达载体，其中引入了表达载体的宿主细胞，其中所述基因已导入或破坏的非人类转基因动物，融合蛋白，抗原肽和抗体到蛋白质。还提供了利用本发明组合物的诊断和治疗方法。

9. 发明授权

US07703726B2 Height-adjustable furnishing system 有权
标题翻译：高度可调的家具系统
公开(公告)号：US07703726B2
公开(公告)日：2010-04-27
申请号：US11580678
申请日：2006-10-13
申请人： Joseph Hunter Harrison , Mary Lee Harrison
发明人： Joseph Hunter Harrison , Mary Lee Harrison
IPC分类号： F16M11/38
CPC分类号： A47B21/00 , A47B9/16 , A47B17/03 , A47B2200/0041 , A47C4/04 , A47D1/02
摘要： A height-adjustable furnishing system includes a base component, a plurality of legs, a height adjustment mechanism, and a platform component. The base has a planar bottom surface and a top surface with a plurality of attachment points for pivotally attaching two, three or four legs. The height-adjustment mechanism is adjustably attached between the base component and at least one of the plurality of legs, or between a forward leg and a rear leg. A platform component is pivotally attached to the plurality of legs to form a parallelogram linkage when viewed from the side. The height-adjustment mechanism may include a gas spring, a cam clamp, a travel block, a release lever, a cable release, a release trigger and may also be hand- or foot-operated. The entire system folds to a generally planar configuration for storage. The legs are erect when they are approximately 10 degrees from vertical.
摘要翻译：高度可调的家具系统包括基座部件，多个腿部，高度调节机构和平台部件。底座具有平坦的底表面和顶表面，其具有用于枢转地附接两个，三个或四个腿的多个附接点。高度调节机构可调节地安装在基座部件与多个腿部中的至少一个之间，或者在前腿和后腿之间。当从侧面观察时，平台部件枢转地附接到多个腿部以形成平行四边形连杆。高度调节机构可以包括气弹簧，凸轮夹，行程块，释放杆，电缆释放，释放触发器，并且还可以是手动或脚踏操作的。整个系统折叠到一般的平面配置以进行存储。当它们距垂直约10度时，双腿直立。

10. 发明授权

US07696316B2 21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, H1983, M1983, 38555 or 593 molecules and uses therefor 失效
标题翻译： 21910,5563,4505,2504,15977,14760,25501,17903,3720,21529,26176,26343,5666,18610,33217,26967，H1983，M1983,38555或593分子及其用途
公开(公告)号：US07696316B2
公开(公告)日：2010-04-13
申请号：US11583766
申请日：2006-10-19
申请人： Rosana Kapeller-Libermann , John Joseph Hunter , Rachel E. Meyers , Laura A. Rudolph-Owen , Rory A. J. Curtis , Peter J. Olandt , Fong-Ying Tsai , Katherine M. Galvin , Miyoung Chun , Mark J. Williamson , Inmaculada Silos-Santiago , Rajasekhar Bandaru
发明人： Rosana Kapeller-Libermann , John Joseph Hunter , Rachel E. Meyers , Laura A. Rudolph-Owen , Rory A. J. Curtis , Peter J. Olandt , Fong-Ying Tsai , Katherine M. Galvin , Miyoung Chun , Mark J. Williamson , Inmaculada Silos-Santiago , Rajasekhar Bandaru
IPC分类号： C07K14/00 , C07H21/04 , C12P21/04 , C12P21/06
CPC分类号： C07K14/47 , A01K2217/05 , C12N9/1235
摘要： The invention provides isolated nucleic acids molecules, designated 21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, h1983, m1983, 38555 and 593 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, h1983, m1983, 38555 and 593 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, h1983, m1983, 38555 or 593 gene has been introduced or disrupted. The invention still further provides isolated 21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, h1983, m1983, 38555 or 593 proteins, fusion proteins, antigenic peptides and anti-21910, 56634, 55053, 2504, 15977, 14760, 25501, 17903, 3700, 21529, 26176, 26343, 56638, 18610, 33217, 21967, h1983, m1983, 38555 or 593 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供分离的核酸分子，命名为21910,5663,55053,2504,15977,14760,25501,17903,3720,21529,26176,26343,5663,18610,33217,21967，h1983，m1983,38555和593核酸分子。本发明还提供反义核酸分子，含有21910,5663,55053,2504,15977,14760,25501,17903,3700,21529,26176,26343,5663,18610,33217,21967，h1983，m1983,3855的重组表达载体和593个核酸分子，其中引入了表达载体的宿主细胞，以及非人类转基因动物，其中21910,5663,5553,2504,15977,14760,25501,17903,3720,21529,26176，已经引入或破坏了18610,33217,21967，h1983，m1983,38555或593基因。本发明还进一步提供分离的21910,5563,4560,25501,17903,3720,21529,26176,26343,5663,18610,33217,21967，h1983，m1983,38555或593蛋白，融合蛋白，抗原肽和抗-19910,563634,55053,2504,15977,14760,25501,17903,3720,21529,26176,26343,56638,18610,33217,21967，h1983，m1983,38555或593抗体。还提供了利用本发明组合物的诊断和治疗方法。

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