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1. 发明申请

US20110125145A1 DEVICES AND METHODS FOR CREATING CONTINUOUS LESIONS 审中-公开
标题翻译：用于创建连续乳房的装置和方法
公开(公告)号：US20110125145A1
公开(公告)日：2011-05-26
申请号：US12815188
申请日：2010-06-14
申请人： Dinesh I. MODY , Dany BERUBE , Ross M. CAROTHERS
发明人： Dinesh I. MODY , Dany BERUBE , Ross M. CAROTHERS
IPC分类号： A61B18/18
CPC分类号： A61B18/1815 , A61B18/14 , A61B18/1492 , A61B18/18 , A61B2018/00214 , A61B2018/00375 , A61B2018/00839 , A61B2018/1475 , A61B2018/1861 , A61B2090/065
摘要： The present invention discloses devices and methods for creating multiple lesions using ablation devices in anatomical regions such as the heart, for example to treat cardiac arrhythmias. The present invention discloses methods and devices to create continuous lesions using area ablation devices. The present invention discloses various embodiments of reference assemblies for accurately positioning ablation devices having ablating portions, especially deployable ablation portions adapted for area ablation. The ablation devices are positioned using the reference assemblies in the anatomy to create one or more lesions. The present invention also discloses several method embodiments for creating continuous lesions using deployable ablating portions to produce two or more overlapping lesions.
摘要翻译：本发明公开了使用解剖区域（例如心脏）中的消融装置来产生多个病变的装置和方法，例如用于治疗心律失常。本发明公开了使用区域消融装置产生连续病变的方法和装置。本发明公开了用于精确地定位具有烧蚀部分的消融装置的参考组件的各种实施例，特别是适用于区域消融的可展开的消融部分。使用解剖学中的参考组件来定位消融装置以产生一个或多个损伤。本发明还公开了使用可展开的消融部分产生两个或更多个重叠病变的多个创建连续病变的方法实施例。

2. 发明授权

US07301131B2 Microwave ablation instrument with flexible antenna assembly and method 失效
标题翻译：微波消融仪具有柔性天线组件及方法
公开(公告)号：US07301131B2
公开(公告)日：2007-11-27
申请号：US11356917
申请日：2006-02-16
申请人： Jules Gauthier , Dany Berube , Hiep Nguyen
发明人： Jules Gauthier , Dany Berube , Hiep Nguyen
IPC分类号： H05B6/64 , A61N1/00
CPC分类号： A61B18/1815 , A61B18/1492 , A61B18/18 , A61B2018/1807 , A61B2018/1861
摘要： A flexible microwave antenna assembly for a surgical ablation instrument capable of conforming to a tissue surface for ablation thereof. The ablation instrument includes a transmission line having a proximal portion suitable for connection to an electromagnetic energy source. The antenna assembly includes a flexible antenna coupled to the transmission line for radially generating an electric field sufficiently strong to cause tissue ablation. A flexible shield device is coupled to the antenna to substantially shield a surrounding area of the antenna from the electric field radially generated therefrom while permitting a majority of the field to be directed generally in a predetermined direction. A flexible insulator is disposed between the shield device and the antenna which defines a window portion enabling the transmission of the directed electric field in the predetermined direction. The antenna, the shield device and the insulator are formed for selective manipulative bending thereof, as a unit, to one of a plurality of contact positions to generally conform the window portion to the biological tissue surface to be ablated.
摘要翻译：一种用于外科消融器械的柔性微波天线组件，其能够符合组织表面以用于其消融。消融器具包括具有适于连接到电磁能源的近端部分的传输线。天线组件包括耦合到传输线的柔性天线，用于径向地产生足够强的电场以引起组织消融。柔性屏蔽装置耦合到天线，以基本上屏蔽天线的周围区域与从其径向产生的电场，同时允许大部分区域通常沿预定方向定向。柔性绝缘体设置在屏蔽装置和天线之间，该天线限定能够沿着预定方向传输定向电场的窗口部分。形成天线，屏蔽装置和绝缘体，用于将其作为一个单元选择性操作地弯曲成多个接触位置中的一个，以将窗口部分大体上与待烧蚀的生物组织表面相一致。

3. 发明授权

US07226446B1 Surgical microwave ablation assembly 失效
标题翻译：手术微波消融组件
公开(公告)号：US07226446B1
公开(公告)日：2007-06-05
申请号：US09660466
申请日：2000-09-12
申请人： Dinesh Mody , Dany Berube , Patrick Morin , Sing-Fatt Chin
发明人： Dinesh Mody , Dany Berube , Patrick Morin , Sing-Fatt Chin
IPC分类号： A61B18/18
CPC分类号： A61B18/18 , A61B18/1477 , A61B18/1815 , A61B2017/00243 , A61B2018/00357 , A61B2018/1425 , A61B2018/183 , A61B2018/1861
摘要： An ablation assembly capable of ablating tissues inside the cavity of an organ is disclosed. The ablation assembly generally includes an ablative energy source and an ablative energy delivery device coupled to the ablative energy source. The ablative energy delivery device is configured for delivering ablative energy sufficiently strong to cause tissue ablation. The ablative energy delivery device generally includes a penetration end adapted to penetrate through a wall of an organ and an angular component that is used to position the device inside the organ after the device has penetrated through the wall of the organ.
摘要翻译：公开了能够烧蚀器官腔内的组织的消融组件。消融组件通常包括消融能量源和耦合到烧蚀能量源的消融能量输送装置。烧蚀能量输送装置被配置为输送足够强的烧蚀能量以引起组织消融。烧蚀能量输送装置通常包括适于穿透器官的壁的穿透端和用于在器械穿过器官壁之后将器件定位在器官内部的角部件。

4. 发明授权

US07099717B2 Catheter having improved steering 失效
公开(公告)号：US07099717B2
公开(公告)日：2006-08-29
申请号：US10039887
申请日：2002-01-03
申请人： Robert E. Woodard , Hiep Nguyen , Dany Berube
发明人： Robert E. Woodard , Hiep Nguyen , Dany Berube
IPC分类号： A61B18/18
CPC分类号： A61B18/1492
摘要： A catheter system with an enhanced steering system, allowing for positioning the distal portion of the catheter proximate to a desired biological target tissue site, is provided. The system includes an elongated tubular member having a steerable distal end configured to deflect, or otherwise direct, and properly position at least a portion of the distal end comprising an ablation device during a surgical procedure allowing for the placement of the deflected portion adjacent or proximate to the target tissue surface. The steering system may alternatively be incorporated into a separate guiding catheter as part of the catheter system.

5. 发明申请

US20060138122A1 Microwave ablation instrument with flexible antenna assembly and method 失效
公开(公告)号：US20060138122A1
公开(公告)日：2006-06-29
申请号：US11356917
申请日：2006-02-16
申请人： Jules Gauthier , Dany Berube , Hiep Nguyen
发明人： Jules Gauthier , Dany Berube , Hiep Nguyen
IPC分类号： H05B3/16
CPC分类号： A61B18/1815 , A61B18/1492 , A61B18/18 , A61B2018/1807 , A61B2018/1861
摘要： A flexible microwave antenna assembly for a surgical ablation instrument capable of conforming to a tissue surface for ablation thereof. The ablation instrument includes a transmission line having a proximal portion suitable for connection to an electromagnetic energy source. The antenna assembly includes a flexible antenna coupled to the transmission line for radially generating an electric field sufficiently strong to cause tissue ablation. A flexible shield device is coupled to the antenna to substantially shield a surrounding area of the antenna from the electric field radially generated therefrom while permitting a majority of the field to be directed generally in a predetermined direction. A flexible insulator is disposed between the shield device and the antenna which defines a window portion enabling the transmission of the directed electric field in the predetermined direction. The antenna, the shield device and the insulator are formed for selective manipulative bending thereof, as a unit, to one of a plurality of contact positions to generally conform the window portion to the biological tissue surface to be ablated.

6. 发明授权

US07033352B1 Flexible ablation instrument 失效
标题翻译：柔性消融仪
公开(公告)号：US07033352B1
公开(公告)日：2006-04-25
申请号：US09484548
申请日：2000-01-18
申请人： Jules Gauthier , Dany Berube , Hiep Nguyen
发明人： Jules Gauthier , Dany Berube , Hiep Nguyen
IPC分类号： A61B18/18
CPC分类号： A61B18/1815 , A61B18/1492 , A61B18/18 , A61B2018/1807 , A61B2018/1861
摘要： A flexible microwave antenna assembly for a surgical ablation instrument capable of conforming to a tissue surface for ablation thereof. The ablation instrument includes a transmission line having a proximal portion suitable for connection to an electromagnetic energy source. The antenna assembly includes a flexible antenna coupled to the transmission line for radially generating an electric field sufficiently strong to cause tissue ablation. A flexible shield device is coupled to the antenna to substantially shield a surrounding area of the antenna from the electric field radially generated therefrom while permitting a majority of the field to be directed generally in a predetermined direction. A flexible insulator is disposed between the shield device and the antenna which defines a window portion enabling the transmission of the directed electric field in the predetermined direction. The antenna, the shield device and the insulator are formed for selective manipulative bending thereof, as a unit, to one of a plurality of contact positions to generally conform the window portion to the biological tissue surface to be ablated.
摘要翻译：一种用于外科消融器械的柔性微波天线组件，其能够符合组织表面以用于其消融。消融器具包括具有适于连接到电磁能源的近端部分的传输线。天线组件包括耦合到传输线的柔性天线，用于径向地产生足够强的电场以引起组织消融。柔性屏蔽装置耦合到天线，以基本上屏蔽天线的周围区域与从其径向产生的电场，同时允许大部分区域通常沿预定方向定向。柔性绝缘体设置在屏蔽装置和天线之间，该天线限定能够沿着预定方向传输定向电场的窗口部分。形成天线，屏蔽装置和绝缘体，用于将其作为一个单元选择性操作地弯曲成多个接触位置中的一个，以将窗口部分大体上与待烧蚀的生物组织表面相一致。

7. 发明申请

US20060015094A1 Vacuum-assisted securing apparatus for a microwave ablation instrument 失效
公开(公告)号：US20060015094A1
公开(公告)日：2006-01-19
申请号：US11227003
申请日：2005-09-14
申请人： Lyndall Erb , Dany Berube , Robert Matheny , Robert Woodard , Theodore Ormsby
发明人： Lyndall Erb , Dany Berube , Robert Matheny , Robert Woodard , Theodore Ormsby
IPC分类号： A61B18/18
CPC分类号： A61B18/14 , A61B18/1402 , A61B18/18 , A61B18/1815 , A61B2018/00291 , A61B2018/00351 , A61B2018/00363 , A61B2018/00577 , A61B2018/1437
摘要： A securing apparatus for selectively securing an ablating element of an ablation instrument proximate to a targeted region of a biological tissue. The securing apparatus includes a support base affixed to the ablation instrument relative the ablating element, and having a support face adapted to seat against the biological tissue proximate to the ablation element. The support base further defines a passage having one end communicably coupled to a vacuum source and an opposite end terminating at an orifice at the support face. The support face together with the biological tissue forms a hermetic seal thereagainst during operation of the vacuum source to secure the ablation instrument thereagainst. Essentially, the hermetic seal and the vacuum source cooperate to form a vacuum force sufficient to retain the ablation device against the biological tissue.

8. 发明授权

US06893436B2 Ablation instrument having a flexible distal portion 失效
标题翻译：消融仪器具有柔性的远端部分
公开(公告)号：US06893436B2
公开(公告)日：2005-05-17
申请号：US10039872
申请日：2002-01-03
申请人： Robert E. Woodard , Hiep Nguyen , Dany Berube
发明人： Robert E. Woodard , Hiep Nguyen , Dany Berube
IPC分类号： A61B17/00 , A61B18/14 , A61B18/18 , A61B19/00
CPC分类号： A61B18/1815 , A61B18/1492 , A61B18/18 , A61B2017/003 , A61B2018/1861 , A61B2090/0454
摘要： An ablation instrument having a flexible portion at or near the distal portion of the instrument, is provided. The instrument includes an elongated tubular member having a steerable distal end configured to deflect, or otherwise direct, and properly position at least a portion of the distal portion, comprising an ablation device, during an ablation procedure. The instrument further includes a deflectable member which cooperates with the steering system allowing for the proper placement of the ablation device adjacent or proximate to the target tissue surface. The steering system may alternatively be incorporated into a separate guiding catheter as part of the catheter system.
摘要翻译：提供了一种在仪器的远端部分或其附近具有柔性部分的消融器械。仪器包括细长的管状构件，其具有可转向的远端，构造成在消融过程期间偏转或以其它方式指导和适当地定位包括消融装置的远侧部分的至少一部分。仪器还包括与转向系统配合的可偏转构件，允许消融装置在目标组织表面附近或邻近处适当放置。转向系统可替代地作为导管系统的一部分并入到单独的引导导管中。

9. 发明授权

US06277113B1 Monopole tip for ablation catheter and methods for using same 失效
标题翻译：用于消融导管的单极尖端及其使用方法
公开(公告)号：US06277113B1
公开(公告)日：2001-08-21
申请号：US09321666
申请日：1999-05-28
申请人： Dany Berube
发明人： Dany Berube
IPC分类号： A01B1804
CPC分类号： A61B18/1492
摘要： An ablation catheter apparatus with a monopole antenna that is arranged to provide a relatively uniform electric field and a method for using such an ablation catheter apparatus are disclosed. According to one aspect of the present invention, an ablation catheter includes an elongated flexible tubular member that is adapted to be inserted into the body of a patient, and a transmission line that is disposed within the tubular member. The transmission line has a distal end and a proximal end which is arranged to be connected to an electromagnetic energy source. The catheter also includes a monopole antenna with tip section and a body section that includes a distal end and a proximal end. The tip section and the body section are arranged to produce a relatively uniform electric field around the monopole antenna which is sufficiently strong to cause tissue ablation. The proximal end of the body section of the monopole antenna is arranged to be electrically coupled to the transmission line.
摘要翻译：公开了一种具有设置成提供相对均匀电场的单极天线的消融导管装置和使用这种消融导管装置的方法。根据本发明的一个方面，消融导管包括适于插入患者体内的细长柔性管状构件和设置在管状构件内的传输线。传输线具有远端和近端，其被布置成连接到电磁能源。导管还包括具有尖端部分的单极天线和包括远端和近端的主体部分。尖端部分和主体部分布置成在单极天线周围产生相当均匀的电场，该电场足够强以引起组织消融。单极天线的主体部分的近端被布置成电耦合到传输线。

10. 发明授权

US06245062B1 Directional reflector shield assembly for a microwave ablation instrument 失效
标题翻译：用于微波消融仪器的定向反射器屏蔽组件
公开(公告)号：US06245062B1
公开(公告)日：2001-06-12
申请号：US09178066
申请日：1998-10-23
申请人： Dany Berube , Robert E. Woodard , Theodore C. Ormsby
发明人： Dany Berube , Robert E. Woodard , Theodore C. Ormsby
IPC分类号： A61B1804
CPC分类号： A61B18/14 , A61B18/1402 , A61B18/18 , A61B18/1815 , A61B2018/00291 , A61B2018/00351 , A61B2018/00363 , A61B2018/00577 , A61B2018/1437
摘要： A directional reflective shield assembly (25) is provided for a microwave ablation instrument (20) having an antenna (23) coupled to a transmission line (21). The antenna (23) is formed to generate an electric field sufficiently strong to cause tissue ablation. The shield assembly (25) includes a cradle device (26) disposed about the antenna (23) in a manner substantially shielding a surrounding area of the antenna (23) from the electric field radially generated therefrom. The cradle device (26) further provides a window portion (27) communicating with the antenna (23) which is strategically located relative the antenna to direct a majority of the field generally in a predetermined direction.
摘要翻译：为具有耦合到传输线（21）的天线（23）的微波消融仪器（20）提供定向反射屏蔽组件（25）。天线（23）被形成为产生足够强的电场以引起组织消融。屏蔽组件（25）包括以基本上屏蔽天线（23）的周围区域与从其径向产生的电场的方式围绕天线（23）设置的支架装置（26）。托架装置（26）还提供与天线（23）通信的窗口部分（27），该天线部分相对于天线在战略上定位，以将大部分的场大致沿预定方向引导。

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