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1. 发明授权

KR102081717B1 (에틴-l,2-디일)비스(이소벤조퓨란-l,3-디온)을 제조하는 방법 有权
公开(公告)号：KR102081717B1
公开(公告)日：2020-02-26
申请号：KR1020147032487
申请日：2013-03-08
申请人： 넥삼 케미컬 에이비
发明人： 로젠베르크,잔-에릭 , 로메,다니엘 , 라게르,에릭 , 몸실로비치,데인
IPC分类号： C07D307/89 , C07D307/87

2. 发明授权

KR101958228B1 신규한 에스트로겐 수용체 리간드 有权
公开(公告)号：KR101958228B1
公开(公告)日：2019-07-04
申请号：KR1020147005645
申请日：2012-08-02
申请人： 카로 바이오 아베
发明人： 청,아이핑 , 가르그,니라지 , 크라제,라즈 , 로프스테드트,조아킴 , 코치,에바 , 코럴,콘라드 , 하그버그,라즈 , 노테버그,대니얼
IPC分类号： C07D333/20 , C07D317/60 , C07D307/87 , C07D277/34 , C07D213/58

3. 发明公开

KR1020130067274A 융합 링을 형성하기 위해 결합하는 치환기를 가지는 트리페닐렌-벤조푸란/벤조티오펜/벤조셀레노펜 화합물 无效
标题翻译：三联苯 - 苯并呋喃/苯并噻吩/苯并噻吩化合物与取代物接合形成熔融环
公开(公告)号：KR1020130067274A
公开(公告)日：2013-06-21
申请号：KR1020127030349
申请日：2011-04-27
申请人： 유니버셜 디스플레이 코포레이션
发明人： 마빈 , 표르델리소제임스 , 유용강 , 광레이먼드
IPC分类号： C09K11/06 , C07D307/87 , H01L51/50 , H05B33/20
CPC分类号： C09K11/06 , C09K2211/1088 , C09K2211/1092 , C09K2211/1096 , H01L51/0054 , H01L51/0072 , H01L51/0074 , H01L51/5012 , H05B33/20 , H05B33/22
摘要： 트리페닐렌 모이어티 및 벤조- 또는 디벤조- 모이어티를 포함하는 화합물을 제공한다. 특히, 상기 벤조- 또는 디벤조- 모이어티는 융합된 치환기를 가진다. 이들 화합물은 특히 황색, 오랜지색 및 적색 에미터와 조합하여 유기 발광 소자 내에서 사용되어 향상된 특성을 가지는 소자를 제공할 수 있다.

4. 发明授权

KR101054224B1 에스시탈로프람의 제조 방법 有权
公开(公告)号：KR101054224B1
公开(公告)日：2011-08-08
申请号：KR1020080090058
申请日：2008-09-11
申请人： 하. 룬트벡 아크티에 셀스카브
发明人： 데파베리카를라 , 마르틴후베르플로리안안톤 , 댄서로버트제임스
IPC分类号： C07D307/87 , A61P25/24
CPC分类号： C07D307/87 , C07C253/34 , C07C255/59
摘要： 본 발명은 라세미 또는 비라세미 거울상체 혼합물인 4-[4-(디메틸아미노)-1-(4'-플루오로페닐)-1-하이드록시부틸]-3-(하이드록시메틸)-벤조니트릴을 그의 단리된 거울상체로 분리하는 방법을 기재하고, 이 방법은 1-프로판올, 에탄올 또는 아세토니트릴을 함유하는 용매계 내에서 O,O'-디-p-톨루오일-타르타르산의 (+)-(S,S)- 또는 (-)-(R,R)-거울상체를 이용하여 4-[4-(디메틸아미노)-1-(4'-플루오로페닐)-1-하이드록시부틸]-3-(하이드록시메틸)-벤조니트릴을 염으로서 분별 결정화하는 단계를 포함한다.

5. 发明公开

KR1020110038893A 석유 제품의 식별방법 및 이에 사용되는 석유 제품용 식별제 有权
标题翻译：用于此处使用的油产品标记油标记的方法
公开(公告)号：KR1020110038893A
公开(公告)日：2011-04-15
申请号：KR1020090096081
申请日：2009-10-09
申请人： 오리엔트화학 (주)
发明人： 김유석
IPC分类号： G01N33/22 , G01N21/31 , C07D307/87
摘要： PURPOSE: A method for distinguishing petroleum products is provided to accurately determine petroleum products by measuring absorbance. CONSTITUTION: A method for distinguishing petroleum products comprises a step of measuring absorbance of petroleum products containing alkyl ether phenolphthalein of chemical formula 1. The petroleum products have maximal absorbance wave length at 240-282 nm. A distinguishing agent for determining petroleum products contains the alkyl ether phenolphthalein derivatives of chemical formula 1.
摘要翻译：目的：提供区分石油产品的方法，通过测量吸光度来准确测定石油产品。构成：区分石油产品的方法包括测定化学式1的含有烷基醚酚酞的石油产品的吸光度的步骤。石油产品在240-282nm处具有最大吸收波长。用于测定石油产品的区别剂含有化学式1的烷基醚酚酞衍生物。

6. 发明公开

KR1020100115622A 헥사히드로무수프탈산의 제조방법 有权
标题翻译：制备十六烷二酸酐的方法
公开(公告)号：KR1020100115622A
公开(公告)日：2010-10-28
申请号：KR1020090034290
申请日：2009-04-20
申请人： 용산화학 주식회사
发明人： 함중각 , 류태근 , 김진영
IPC分类号： C07D307/89 , C07D307/87
摘要： PURPOSE: A method for preparing hexahydrophthalic acid anhydride is provided to prevent impurity generation and to prepare hexahydrophthalic acid anhydride without melting point reduction. CONSTITUTION: A hexahydrophthalic acid is prepared by hydrogenation of tetrahydrophthalic acid under the presence of hydrogenation catalyst. The hydrogenation catalyst is obtained by pretreatment of a catalyst containing palladium using acid and alkali solution. The hydrogenation is performed without separate reaction solution. The tetrahydrophthalic acid is unpurified crude-tetrahydrophthalic acid or purified pure-tetrahydrophthalic acid which is a reactant of anhydrous maleic acid and 1,3-butadiene.
摘要翻译：目的：提供一种制备六氢邻苯二甲酸酐的方法，以防止杂质产生并制备六氢邻苯二甲酸酐而不降低熔点。构成：在氢化催化剂存在下氢化四氢邻苯二甲酸制备六氢邻苯二甲酸。氢化催化剂通过使用酸和碱溶液预处理含钯催化剂而获得。无需单独的反应溶液进行氢化。四氢邻苯二甲酸是未纯化的粗四氢邻苯二甲酸或纯化的四氢邻苯二甲酸，其是无水马来酸和1,3-丁二烯的反应物。

7. 发明公开

KR1020100051615A 붕소를 함유하는 소분자 有权
标题翻译：含硼的小分子
公开(公告)号：KR1020100051615A
公开(公告)日：2010-05-17
申请号：KR1020107001062
申请日：2008-06-19
申请人： 아나코르 파마슈티칼스 인코포레이티드
发明人： 베이커,스티븐,제이. , 에르난데스,빈센트,에스. , 샤르마,라시미 , 니먼,제임스,에이. , 아카마,츠토마 , 장,용-강 , 플레트너,제이콥,제이. , 앨리,마이클,리차드,케빈 , 싱,라제시워 , 시아,이 , 조우,후첸 , 모하마드,라힘 , 케라만,엘메흐디 , 루,샤오송 , 하,민 , 필립스,제임스,쥐.
IPC分类号： C07D307/87 , C07D307/88 , C07F5/02
CPC分类号： C07F5/025 , A61K31/69 , Y02A50/387
摘要： This invention provides, among other things, novel compounds useful for treating bacterial infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
摘要翻译：本发明尤其提供了可用于治疗细菌感染的新化合物，含有这些化合物的药物组合物，以及这些化合物与至少一种另外的治疗有效药物的组合。

8. 发明授权

KR100887207B1 시탈로프람의 제조 방법 失效
标题翻译：方法制备CITALOPRAM
公开(公告)号：KR100887207B1
公开(公告)日：2009-03-06
申请号：KR1020037001900
申请日：2001-08-14
申请人： 하. 룬트벡 아크티에 셀스카브
发明人： 페테르센한스 , 아마디안할레 , 댄서로버트
IPC分类号： C07D307/87
CPC分类号： C07D307/87
摘要： Preparation of citalopram (I) involves conversion of a 5-halogenated compound (II) to a 5-carboxylic acid intermediate (III) followed by conversion of (III) to (I). - Preparation of citalopram (1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-5-isobenz ofurancarbonitrile) (I) involves conversion of 5-halogenated compound of formula (II) to a 5-carboxylic acid intermediate of formula (III) followed by conversion of (III) to (I). - Z = halo. - An INDEPENDENT CLAIM is included for the preparation of compounds of formula (III) and (V). - X = halo, CN, OR5, SR6 or NR7R8; - R5, R6 = 1-6C alkyl, (hetero)aryl or benzyl (all optionally substituted with T); - T = halo, 1-4C alkyl, cyano, -OH, 1-4C alkoxy, trifluoromethyl, nitro, amino, mono- or di-(1-4C)alkylamino; - Y = O, S or NR9; and - R7-R9 = R5 or H. - ACTIVITY - Antidepressant. - MECHANISM OF ACTION - Serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitor. - No biological data given.

9. 发明公开

KR1020080108629A 에스시탈로프람의 제조방법 无效
标题翻译： 에스시탈로프람의제조방법
公开(公告)号：KR1020080108629A
公开(公告)日：2008-12-15
申请号：KR1020087029127
申请日：2002-07-12
申请人： 하. 룬트벡 아크티에 셀스카브
发明人： 베크소메르미카엘 , 닐센올레 , 페테르센한스 , 아마디안할레 , 페데르센헨리크 , 브레센페테르 , 가이저피오나 , 리제임스 , 콕스제프리 , 다프레몽올리비에 , 쉬뚜크리스띠나 , 어센자세바스티안피 , 하리하란샨카 , 나이르어샤
IPC分类号： C07D307/87
CPC分类号： C07C215/32 , C07D307/87
摘要： A novel method is provided for the manufacture of escitalopram. The method comprises chromatographic separation of the enantiomers of citalopram or an intermediate in the production of citalopram using a chiral stationary phase such as ChiralpakTM AD or Chiralcel TM OD. Novel chiral intermediates for the synthesis of Escitalopram made by said method are also provided. ® KIPO & WIPO 2009
摘要翻译：提供了一种用于制造艾司西酞普兰的新方法。该方法包括使用手性固定相如ChiralpakTM AD或Chiralcel TM OD色谱分离西酞普兰的对映异构体或西酞普兰生产中的中间体。还提供了由所述方法制备的用于合成依他普仑的新的手性中间体。 ®KIPO＆WIPO 2009

10. 发明公开

KR20070078962A BENZOFURAN COMPOUNDS WITH PEPTIDE DEFORMYLASE-INHIBITORY ACTIVITY PRODUCED BY ASPERGILLUS FLAVIPES F543 AND THEIR ANTIBACTERIAL ACTIVITY 审中-公开
标题翻译：具有由ASPERGILLUS FLAVIPES F543生产的肽类抗坏血酸酶抑制活性的苯佐芬化合物及其抗菌活性
公开(公告)号：KR20070078962A
公开(公告)日：2007-08-03
申请号：KR20060048804
申请日：2006-05-30
申请人： KOREA RES INST OF BIOSCIENCE
发明人： KIM WON GON , KWON YUN JU
IPC分类号： C07D307/87 , C12N1/20
摘要： Provided are novel benzofuran compounds which shows excellent peptide-deformylase-inhibitory activity and has antibacterial activity against pathogenic microorganisms such as Methicillin-resistant Staphylococcus aureus(MRSA) and Quinolone-resistant Staphylococcus aureus(QRSA) and strong antibacterial activity against Actinobacillus pleuropneumoniae, Bordetella bronchiseptica, and Pasteurella multocida. The compounds having peptide-deformylase-inhibitory activity are represented by the following F541-1 and F543-2. The pharmaceutical composition comprises the compounds or a derivative thereof including a stereoisomer or a pharmaceutically acceptable salt thereof or a pharmaceutically acceptable carrier. The Aspergillus flavipes F543 producing the compounds of the F541-1 and F543-2 is deposited as a deposition number of KCTC10880BP.
摘要翻译：提供了显示优异的肽 - 变形酶抑制活性的新型苯并呋喃化合物，并且具有抗甲氧西林金黄色葡萄球菌（MRSA）和喹诺酮耐药金黄色葡萄球菌（QRSA）等病原微生物的抗菌活性，对胸膜肺炎放线杆菌，支气管炎博德特氏菌具有强抗菌活性和多杀巴斯德氏菌具有肽 - 变形酶抑制活性的化合物由以下F541-1和F543-2表示。药物组合物包含化合物或其衍生物，包括其立体异构体或其药学上可接受的盐或药学上可接受的载体。产生F541-1和F543-2化合物的曲霉黄曲霉F543作为KCTC10880BP的沉积编号进行保藏。

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