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    • 1. 发明公开
    • 정수압력 시도에 의한 동결보존된 생물학적 물질의 융해 후생존력 향상
    • 通过静水压力挑战改善生物生物材料的后期生存
    • KR1020060123090A
    • 2006-12-01
    • KR1020067004902
    • 2004-09-08
    • 크리오-이노베이션 케이에프티.
    • 프리벤스쯔키,차바몰나르,미클로스
    • A01N1/02
    • A01N1/0289A01N1/02
    • The present invention relates to a method for improving post-thaw survival of cryopreserved biological material comprising applying hydrostatic pressure to said biological material; keeping the said biological material at the hydrostatic pressure for a predetermined time period; releasing the hydrostatic pressure; and freezing the said biological material using any protocol applicable thereto. The invention also relates to the use of a pressurizing device for the pretreatment of a biological material that is to be cryopreserved, as well as to a pressurizing device for the pretreatment of a biological material that is to be cryopreserved, said device comprising a pressure chamber for receiving biological material, means to produce said pressure, and means to maintain said pressure in said chamber.
    • 本发明涉及一种用于改善冷冻保存的生物材料的解冻后存活的方法,包括对所述生物材料施加静水压力; 将所述生物材料保持在静水压力达预定时间段; 释放静水压力; 并使用适用于其的任何方案冷冻所述生物材料。 本发明还涉及一种加压装置用于对待冷冻保存的生物材料进行预处理的加压装置以及用于预冷冻待生物材料的加压装置,所述装置包括压力室 用于接收生物材料,产生所述压力的装置,以及在所述室中保持所述压力的装置。
    • 5. 发明公开
    • 고압 저온 챔버
    • 高压致死气泡
    • KR1020080011307A
    • 2008-02-01
    • KR1020077027873
    • 2006-05-02
    • 베리 리마 가스톤 제로니모
    • 베리리마가스톤제로니모
    • C12M1/38C12M1/00
    • A01N1/0289A01N1/0257A01N1/0284C12M41/12
    • The Hyperbaric Criogenesis Chambers are equipment for medical usage, extracorporeal, and capable of promoting the proliferation and preservation of cells in a way mainly microbiologic, "not biologic". They are compartments with containers that host tissues or cells in solution with nutrients, that bear pressures higher and lower to sea level They have a cold system inside that lowers the environmental temperature and maintains it permanently. They are for maintaining viability of cells or tissues and to induce their organized proliferation with oxygen or other gases at pressures higher or lower that the exterior of the chamber.
    • 高压致死发生室是医疗用途,体外和促进细胞增殖和保存的设备,主要以微生物学,“不生物学”为主。 它们是具有容器的隔室,其容纳有营养物质的溶液中的组织或细胞,其承受高于和低于海平面的压力。它们具有降低环境温度并保持其永久性的冷系统。 它们用于维持细胞或组织的存活力,并且在高于或低于室的外部的压力下用氧气或其它气体诱导其有组织的增殖。
    • 6. 发明公开
    • 제어된 환경을 유지하는 장치
    • 维持受控环境的设备
    • KR20180035890A
    • 2018-04-06
    • KR20187006171
    • 2016-08-02
    • F26B5/06A01N1/02B01L7/00B01L9/06F26B25/06
    • F26B5/06A01N1/0252A01N1/0289B01L7/00B01L9/06B01L2200/0689B01L2300/042B01L2300/0829B01L2300/1894B01L2400/049F26B25/063
    • 동결건조네스트및 이를사용하는방법이본원에기재된다. 다양한실시예에서, 동결건조네스트는동결건조네스트의내부공간내에하나이상의물질을각각지지하는하나이상의용기를지지하도록구성된다. 내부공간은동결건조네스트의표면을통해연장되는하나이상의벤트구멍을통해동결건조네스트의외부와유체연통될수 있다. 하나이상의벤트구멍각각은벤트구멍내에기밀밀봉을선택적으로형성하도록구성된대응밀봉요소를가지므로, 동결건조네스트를둘러싼주위조건이동결건조조건이아닐때 내부공간내에제어된환경이유지될수 있다. 하나이상의밀봉요소는기밀밀봉을형성하도록밀봉요소를대응하는벤트구멍내로함몰함으로써동결건조네스트가밀봉된동결건조기내에배치되는동안작동될수 있다.
    • 本文描述了冻干巢和使用它们的方法。 在各种实施方案中,冻干窝被构造成支撑至少一个容器,用于分别在冷冻干燥的巢的内部空间支撑所述一种或多种材料。 内部空间可与流体的冷冻干燥的巢的外部穿过所述冷冻干燥的巢的表面延伸的至少一个通气孔连通。 一个或多个排气孔分别因为配置为选择性地形成通气孔内的气密密封的相应的密封元件的,有在内部空间内的受控环境时围绕所述冻干巢不是环境条件冷冻干燥条件下进行维护。 可设置在冷冻操作的至少一个密封元件被用于冷冻干燥的巢密封抑郁干燥器成对应于所述密封元件通气孔进行,以形成气密密封。