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2. 发明公开

KR1020080016799A 궤양성 대장염 또는 간질성 폐렴의 병기 판정 방법 및 그를위한 시약 키트 有权
标题翻译：用于临床分期的临床分析方法或间质性肺炎及其试剂盒
公开(公告)号：KR1020080016799A
公开(公告)日：2008-02-22
申请号：KR1020077026365
申请日：2006-04-14
申请人： 후지와라, 무쯔노리 , 오까야스, 이사오 , 하야시, 유조 , 후지레비오 가부시키가이샤
发明人： 후지와라,무쯔노리 , 오까야스,이사오 , 하야시,유조
IPC分类号： G01N33/493 , G01N33/53 , G01N33/577
CPC分类号： G01N33/88 , G01N2800/065 , G01N2800/12 , Y10T436/201666
摘要： Disclosed is a method for clinical staging of ulcerative colitis or interstitial pneumonia which can determine the clinical condition readily and is useful for the selection of a therapeutic agent to be used, the determination of the therapeutic level of a treatment applied and the determination of whether the dispensing of a therapeutic agent is to be ceased or not or the like, unlike to conventional staging methods for in which the clinical stage is determined by the observation of a lesion on the mucosa by an endoscope which requires some experience of a practitioner or the analysis of a pathological tissue specimen collected from a living body, the method being capable of determining the clinical stage quantitatively by determining a substance contained in the urine in a numerical form. The concentration of a prostaglandin E-main urinary metabolite (PGE-MUM) in the urine is measured to determine the pre-remission phase and the remission phase of ulcerative colitis. Similarly, the concentration of a prostaglandin E-main urinary metabolite (PGE-MUM) in the urine is measured to determine the active phase and the inactive phase of interstitial pneumonia ulcerative colitis.
摘要翻译：公开了一种临床分期的溃疡性结肠炎或间质性肺炎的方法，其可以容易地确定临床状况，并且可用于选择所用治疗剂，确定所用治疗的治疗水平以及是否确定治疗剂的分配不会停止或不等于常规的分期方法，其中临床阶段通过内窥镜观察粘膜上的病变来确定，该内窥镜需要一些从业者的经验或分析从生物体收集的病理组织样本，该方法能够通过以数字形式确定尿中所含的物质来定量地确定临床阶段。测量尿中前列腺素E主要尿代谢物（PGE-MUM）的浓度，以确定溃疡性结肠炎的缓解期和缓解期。类似地，测量尿中前列腺素E主要尿代谢物（PGE-MUM）的浓度以确定间质性肺炎溃疡性结肠炎的活动期和无活性期。

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