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    • 5. 发明公开
    • 유용성 활성물질 함유 미세캡슐 입자, 이의 제조방법 및 이를 포함하는 화장료 조성물
    • 含有活性化合物的精细胶囊,生产方法和含有它的化妆品组合物
    • KR1020100120731A
    • 2010-11-17
    • KR1020090039517
    • 2009-05-07
    • 한불화장품주식회사
    • 김형주김태훈강기춘표형배
    • A61K8/11A61K9/50A61Q19/00A61K8/84
    • PURPOSE: A microcapsule particle containing lipophilic active substance with low solubility and stability is provided to improve solubility and stability in a formulation. CONSTITUTION: A method for preparing microcapsule particle in which a lipophilic active substance with low solubility an stability is stabilized comprises: a step of dissolving lipophilic active substance and polycaprolactone, poly(D,L-lactide) or poly(L-lactide) biodegradable polymer with water in a volatile organic solvent; a step of dispersing and stirring the solution in water to form particles; and a step of evaporating the volatile organic solvent. The lipophilic acid substance is rosmarinic acid. A cosmetic composition contains the microcapsule particle.
    • 目的:提供一种含有低溶解度和稳定性的亲脂性活性物质的微胶囊颗粒,以改善制剂中的溶解性和稳定性。 构成:一种制备微胶囊颗粒的方法,其中稳定性稳定的溶解度低的亲脂性活性物质包括:将亲脂性活性物质和聚己内酯,聚(D,L-丙交酯)或聚(L-丙交酯)生物降解聚合物 用水在挥发性有机溶剂中; 将溶液分散并搅拌在水中以形成颗粒的步骤; 和蒸发挥发性有机溶剂的步骤。 亲脂性酸物质是迷迭香酸。 化妆品组合物含有微胶囊颗粒。
    • 6. 发明授权
    • 선바위고사리 추출물을 함유하는 피부 외용제 조성물
    • 含有燕麦提取物的护肤剂
    • KR100986129B1
    • 2010-10-07
    • KR1020080030150
    • 2008-04-01
    • 한불화장품주식회사
    • 김진화오정영이근수이동환장영학표형배강기춘
    • A61K8/97A61Q19/08A61Q19/02A61Q19/00
    • 본 발명은 선바위고사리 추출물을 함유하는 피부 외용제 조성물에 관한 것으로서, 좀더 구체적으로는 고사리목 고사리과의 선바위고사리의 전초(全草) 추출물을 활성성분으로 0.001 - 30.0중량%, 바람직하게는 0.01 - 5중량%를 함유하는 것을 특징으로 하는 활성산소 소거효과, 주름개선효과, 미백효과, 보습효과, 피부자극 완화효과, 여드름방지효과, 아토피 개선효과 및 항염효과, 모발손상 방지효과, 탈모방지 및 육모 효과가 우수한 피부 외용제 조성물에 관한 것이다. 본 발명에 의하면 선바위고사리 추출물은 활성산소 소거효과뿐만 아니라, 사람 섬유아세포에서 MMP-1 생합성 저해효과와 타입 1 프로콜라겐의 생합성 촉진에 의한 피부 탄력 및 잔주름 개선효과, 미백효과, 보습효과, 피부자극 완화효과, 여드름 방지효과, 아토피 개선효과, 항염효과, 모발손상 방지효과, 탈모방지 및 육모 효과를 나타낸다.
      선바위고사리 추출물, 항노화용 화장료, 주름 개선효과, 미백효과, 보습효과, 모발손상방지효과, 탈모방지 및 육모 효과, 피부자극 완화효과, 여드름 방지효과, 아토피 피부개선효과, 항염효과, 피부 외용제
    • 7. 发明公开
    • 저분자량 달팽이 점액 분해물 제조방법 및 이를 함유하는 화장료 조성물
    • 低分子量SNAIL MUCIN HYDROLYZATE制备方法和含有该化合物的化妆品组合物
    • KR1020140052128A
    • 2014-05-07
    • KR1020120116401
    • 2012-10-19
    • 한불화장품주식회사
    • 이근수이동환강기춘이청희표형배
    • A61K8/98A61K8/66A61Q19/00
    • A61K8/987A61K8/64A61K35/618A61Q19/08
    • The present invention relates to a method for producing low molecular snail mucus decomposed material and a cosmetic composition containing same as an active ingredient. More specifically, the present invention relates to a method for producing active low molecular snail mucus decomposed material having a major molecular weight distribution in a molecular amount range of 500-5,000 dalton and a cosmetic composition that contains the snail mucus decomposed material of 0.001-30.0 wt%, prevents damage to the skin caused by ultraviolet rays, moistens the skin, reduces skin wrinkles, and improves skin elasticity, wherein the method comprises the steps of: decomposing high molecular snail mucus by adding a proteolytic enzyme and one or more enzymes selected from chondroitin lyase ABC and hyaluronate lyase in the mucus that is extracted from a snail; selectively separating active low molecular decomposed material; removing insoluble precipitation including inactive polymers through centrifuging and filtering; and performing concentration, freezing, and drying.
    • 本发明涉及一种生产低分子蜗牛粘液分解材料的方法和含有它们作为活性成分的化妆品组合物。 更具体地说,本发明涉及一种生产分子量范围为500-5,000道尔顿的主要分子量低的蜗牛粘液分解材料的方法和含有0.001-30.0的蜗牛粘液分解物的化妆品组合物 重量%,防止紫外线引起的皮肤损伤,润湿皮肤,减少皮肤皱纹,改善皮肤弹性,其中该方法包括以下步骤:通过加入蛋白水解酶和选择一种或多种酶来分解高分子蜗牛粘液 从软骨提取的粘液中的软骨素裂解酶ABC和透明质酸裂解酶; 选择性分离活性低分子分解物; 通过离心和过滤除去包括无活性聚合物的不溶性沉淀; 并进行浓缩,冷冻和干燥。
    • 8. 发明公开
    • 혈령지 발효물을 함유하는 피부 외용제 조성물
    • 含有发芽的ARENARIA KANSUENSIS MAXIM的皮肤组合物。 提取
    • KR1020120103225A
    • 2012-09-19
    • KR1020110021374
    • 2011-03-10
    • 한불화장품주식회사
    • 배준태이근수김진화강기춘표형배
    • A61K36/36A61P17/00
    • PURPOSE: An external use skin composition containing Arenaria kansuensis Maxim. fermentation is provided to improve antioxdiation, anti-wrinkling, whitening, and moisturizing effects and to promoter collagen synthesis. CONSTITUTION: An external use skin composition contains Arenaria kansuensis Maxim. fermentation as an active ingredient. A method for preparing the fermentation comprises: a step of preparing Arenaria kansuensis Maxim.extract; a step of mixing the extract and Grifolafrondosa (KCTC 10337BP) mycelium or culture liquid of the mycelium and culturing the mixture; and a step of removing the mycelium from the culture liquid and collecting filtered liquid. The composition contains 0.001-30.0 wt% of the filtered liquid. An extraction solvent is 85-99%(v/v) ethanol. The composition is used for skin whitening, anti-aging, skin irritation relieving, atopic dermatitis treatment, or acne prevention.
    • 目的:一种外用皮肤组合物,含有甘草。 提供发酵以改善抗氧化,抗皱,增白和保湿作用,促进胶原合成。 构成:外用皮肤组合物含有甘草。 发酵为活性成分。 一种制备发酵的方法,包括:制备甘蓝大豆提取物的步骤; 将提取物和Grifolafondondosa(KCTC 10337BP)菌丝体或菌丝体培养液混合并培养混合物的步骤; 以及从培养液中除去菌丝体并收集过滤液体的步骤。 该组合物含有0.001-30.0重量%的过滤液体。 提取溶剂为85-99%(v / v)乙醇。 该组合物用于皮肤美白,抗衰老,皮肤刺激缓解,特应性皮炎治疗或预防痤疮。