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    • 3. 发明授权
    • 고순도 메티오졸린의 공업적 제조방법
    • 高纯度甲硫唑啉的制备方法
    • KR101201203B1
    • 2012-11-15
    • KR1020120033835
    • 2012-04-02
    • 한국화학연구원주목우연구소
    • 고영관구동완우재춘류재욱구석진황기환이동국정근회전만석김성헌임종수조남규
    • C07D413/04
    • C07D413/04B01J31/0271
    • PURPOSE: An industrial method for preparing [5-{(2,6-difluorobenzyloxy)methyl}-4,5-dihydro-5-methyl-3-(3-methylthiophene-2-yl)-isoxazole](methiozolin) is provided to obtain a large amount of the methiozolin of high purity and to cultivate agricultural crops. CONSTITUTION: A method for preparing thiozolin(chemical formula 1) comprises: a step of reacting 4,5-dihydro-5-methyl-3-{(3-methylthiophene-2-yl)-isoxazole-5-yl}methanol of chemical formula 2 with 2,6-difluorobenzyl(chloride or bromide) of chemical formula 3 using an alkali metal base and a phase converting catalyst in a mixture of water and organic solvent at 50-100 Deg. C. to prepare the concentrate of an organic layer; and a step of crystallizing the concentrate in a mixture solvent of water/ethanol, water/isopropanol, or C1-C3 alcohol/n-heptane. The organic solvent is benzene, toluene, xylene, chlorobenzene, or 1,2-dichloroethane. The alkali metal base is sodium hydroxide, potassium hydroxide, or lithium hydroxide.
    • 目的:提供制备[5 - {(2,6-二氟苄氧基)甲基} -4,5-二氢-5-甲基-3-(3-甲基噻吩-2-基) - 异恶唑](甲氧基)唑的工业方法) 获得大量高纯度的甲氧唑啉并培育农作物。 构成:制备噻唑啉(化学式1)的方法包括:将化合物的4,5-二氢-5-甲基-3 - {(3-甲基噻吩-2-基) - 异恶唑-5-基}甲醇 式2与化学式3的2,6-二氟苄基(氯化物或溴化物)使用碱金属碱和相转化催化剂在水和有机溶剂的混合物中在50-100℃下反应。 C.制备有机层的浓缩物; 以及将浓缩物在水/乙醇,水/异丙醇或C 1 -C 3醇/正庚烷的混合溶剂中结晶的步骤。 有机溶剂为苯,甲苯,二甲苯,氯苯或1,2-二氯乙烷。 碱金属碱是氢氧化钠,氢氧化钾或氢氧化锂。
    • 4. 发明授权
    • 술포닐우레아 화합물의 잔디용 제초제로서의 용도
    • 磺酰氟化合物作为除草剂的用途
    • KR100883275B1
    • 2009-02-18
    • KR1020080077249
    • 2008-08-07
    • 주목우연구소
    • 구석진황기환전만석김성헌
    • A01N43/64A01N31/08
    • A01N47/36
    • A herbicide for lawn grass of sulfonylurea compound is provided to weed selectively graminaceae, cyperaceae and broadleaf weed by including benzene sulfonyl urea derivative compound or thiophene sulfonyl urea derivative compound. A herbicide for lawn grass includes benzene sulfonyl urea derivative compound indicated by a general formula(I) as active ingredient and weeds selectively finger grass, annual meadow-grass, green kyllinga in warm-season grasses like Korea Zoysia japonica and cool-season grass like bentgrass and Kentucky bluegrass. In the equation (I): R is haloalkyl; X and Y are CH3, OCH3 or Cl; Cl are shown. Z is CH or N.
    • 通过包括苯磺酰脲衍生物化合物或噻吩磺酰脲衍生物化合物,将草酰草胺草酰草除草剂提供给杂草选择性禾谷镰刀菌,莎草科和阔叶杂草。 草坪草除草剂包括由通式(I)表示的苯磺酰脲衍生物作为活性成分,并且选择性手指草,一年生草地草,绿色麒麟草在诸如韩国札幌的凉季草和凉季草 弯草和肯塔基蓝草。 在式(I)中:R是卤代烷基; X和Y是CH 3,OCH 3或Cl; Cl被显示。 Z是CH或N.
    • 5. 发明授权
    • 제초성 5-벤질옥시메틸-1,2-이속사졸린 유도체 화합물의용도
    • 除草剂5-苯甲酰基甲基-1,2 - 异恶唑衍生物的用途
    • KR100814420B1
    • 2008-03-18
    • KR1020070061711
    • 2007-06-22
    • 주목우연구소
    • 구석진황기환
    • A01N43/72A01P13/00
    • A01N43/80
    • A 5-benzyloxymethyl-1,2-isoxazoline derivative compound is provided to show high herbicidal activity as an upland herbicide as well as high herbicidal activity on lawn grass and seeded rice, thereby being used as a herbicide for lawn grass or seeded rice. A herbicide for lawn grass comprises a 5-benzyloxymethyl-1,2-isoxazoline derivative represented by a formula(I) as an effective ingredient and is treated by Zoysiagrass, cool season turfgrasses, bentgrass, kentucky bluegrass, perennial ryegrass and warm season turfgrasses before or after germination to weed selectively finger grass and annual bluegrass. In the formula(I), each X1, X2, and X3 is independently H, methyl, halogen, methoxy or nitro(provided that all of the X1, X2 and X3 being H is excepted); and each Y1, Y2 and Y3 is independently H or F. A herbicide for lawn grass comprises 5-(2,6-difluorobenzyl)oxymethyl-5-methyl-3-(4-methylthiophene-5-yl)-1,2-isoxazoline represented by the formula(II) as an effective ingredient, a solid media, a liquid media or a surfactant.
    • 提供5-苄氧基甲基-1,2-异恶唑啉衍生物化合物,以显示作为高地除草剂的高除草活性以及对草坪草和播种稻的高除草活性,从而用作草坪草或播种稻的除草剂。 用于草坪草的除草剂包括由式(I)表示的5-苄氧基甲基-1,2-异恶唑啉衍生物作为有效成分,并且经由Zoysiagrass,冷季草坪草,弯草,肯塔基蓝草,多年生黑麦草和温季草坪草处理 或在发芽后用杂草选择性手指草和一年生草坪。 在式(I)中,X 1,X 2和X 3各自独立地为H,甲基,卤素,甲氧基或硝基(条件是X1,X2和X3全部除外)。 并且每个Y1,Y2和Y3独立地为H或F.草坪草除草剂包含5-(2,6-二氟苄基)氧甲基-5-甲基-3-(4-甲基噻吩-5-基) 由式(II)表示的异恶唑啉作为有效成分,固体介质,液体介质或表面活性剂。