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1. 发明授权

KR101608979B1 서열번호 5를 포함하는 살조활성 단백질분해효소, 이를 코딩하는 유전자 및 이를 포함하는 살조제제 有权
标题翻译： 5具有编码其的杀伤活性基因的序列5及其包含的ALGICIDAL制剂
公开(公告)号：KR101608979B1
公开(公告)日：2016-04-05
申请号：KR1020140191149
申请日：2014-12-26
申请人： 한국해양과학기술원
发明人： 김상진 , 강성균 , 권개경 , 이정현 , 이현숙 , 강지현 , 손재학
IPC分类号： C12N9/52 , C12N15/52 , A01N63/00
CPC分类号： A01N63/00
摘要： 본발명은살조활성단백질분해효소, 이를코딩하는유전자및 이를포함하는살조제제에관한것으로, 본발명의단백질분해효소는살조활성이우수하므로, 적조발생지역에서적조의방제에유용하게사용될수 있다.

2. 发明公开

KR1020150014425A 서열번호 7를 포함하는 살조활성 단백질분해효소, 이를 코딩하는 유전자 및 이를 포함하는 살조제제 审中-实审
标题翻译：具有杀伤活性的序列7的抗原，编码该基因的基因和包含其的杀伤细胞制剂
公开(公告)号：KR1020150014425A
公开(公告)日：2015-02-06
申请号：KR1020140191153
申请日：2014-12-26
申请人： 한국해양과학기술원
发明人： 김상진 , 강성균 , 권개경 , 이정현 , 이현숙 , 강지현 , 손재학
IPC分类号： C12N9/52 , C12N15/52 , A01N63/00
CPC分类号： A01N63/00 , C12N9/52 , C12N15/52 , Y10S435/816
摘要： The present invention relates to a protease having an algicidal activity, a gene encoding the same, and an algicidal formulation including the same. The protease of the present invention has the excellent algicidal formulation, thereby being used in control of red tide in a red tide occurrence area. Specifically, provided is a method for controlling red tide which is characterized by comprising the steps of: producing at least one protease selected from a group consisting of sequence number 1, 7, and 27 by using a Kordia algicida OT1 strain (KCTC 11320BP); and putting an algicidal formulation which contains the produced protease as an active component into sea.
摘要翻译：本发明涉及具有杀藻活性的蛋白酶，编码该蛋白酶的基因，以及包含其的杀藻剂。本发明的蛋白酶具有优异的杀藻剂配方，因此用于防治红潮发生地区的红潮。具体地说，提供了一种控制红潮的方法，其特征在于包括以下步骤：通过使用Kordia algicida OT1菌株（KCTC 11320BP）制备至少一种选自序列号1，7和27的蛋白酶; 并将含有所产生的蛋白酶作为活性成分的杀藻剂制剂放入海中。

3. 发明公开

KR1020150009509A 서열번호 4를 포함하는 살조활성 단백질분해효소, 이를 코딩하는 유전자 및 이를 포함하는 살조제제 有权
标题翻译：具有杀伤活性的序列4的抗体，编码其的基因和包含其的碱性制剂
公开(公告)号：KR1020150009509A
公开(公告)日：2015-01-26
申请号：KR1020140191148
申请日：2014-12-26
申请人： 한국해양과학기술원
发明人： 김상진 , 강성균 , 권개경 , 이정현 , 이현숙 , 강지현 , 손재학
IPC分类号： C12N9/52 , C12N15/52 , A01N63/00
CPC分类号： A01N63/00 , C12N9/52 , C12N15/52 , Y10S435/816
摘要： The present invention relates to a protease of sequence number 5 having algicidal activity, a gene encoding the same, and an algicidal preparation including the same. The protease of the present invention has excellent algicidal activity, and thus can be useful in controlling red algal blooms in a red tide occurrence area. Provided in the present invention are a protease with algicidal activity having any one amino acid sequence among sequence number 1, 4 to 7, 26, and 27, and a gene encoding the protease.
摘要翻译：本发明涉及具有杀藻活性的序列号5的蛋白酶，编码该蛋白酶的基因，以及包含其的杀藻剂制剂。本发明的蛋白酶具有优异的杀藻活性，因此可用于防治红潮发生地区的红藻。本发明提供具有杀菌活性的蛋白酶，其具有序列号1,4至7,26和27之间的任何一个氨基酸序列，以及编码该蛋白酶的基因。

4. 发明授权

KR101756769B1 서열번호 1의 살조활성 단백질분해효소, 이를 코딩하는 유전자 및 이를 포함하는 살조제제 有权
公开(公告)号：KR101756769B1
公开(公告)日：2017-07-12
申请号：KR1020080054757
申请日：2008-06-11
申请人： 한국해양과학기술원
发明人： 김상진 , 강성균 , 권개경 , 이정현 , 이현숙 , 강지현 , 손재학
IPC分类号： C12N9/50 , C12N9/00
CPC分类号： C12N9/50 , A01N63/00
摘要： 본발명은살조활성단백질분해효소, 이를코딩하는유전자및 이를포함하는살조제제에관한것으로, 본발명의단백질분해효소는살조활성이우수하므로, 적조발생지역에서적조의방제에유용하게사용될수 있다.

5. 发明授权

KR101608977B1 서열번호 4를 포함하는 살조활성 단백질분해효소, 이를 코딩하는 유전자 및 이를 포함하는 살조제제 有权
标题翻译： 4具有编码与其相同的杀伤活性基因的序列4的抗体及其包含的ALGICIDAL制剂
公开(公告)号：KR101608977B1
公开(公告)日：2016-04-05
申请号：KR1020140191148
申请日：2014-12-26
申请人： 한국해양과학기술원
发明人： 김상진 , 강성균 , 권개경 , 이정현 , 이현숙 , 강지현 , 손재학
IPC分类号： C12N9/52 , C12N15/52 , A01N63/00
CPC分类号： A01N63/00
摘要： 본발명은살조활성단백질분해효소, 이를코딩하는유전자및 이를포함하는살조제제에관한것으로, 본발명의단백질분해효소는살조활성이우수하므로, 적조발생지역에서적조의방제에유용하게사용될수 있다.

6. 发明公开

KR1020080108921A 서열번호 1의 살조활성 단백질분해효소, 이를 코딩하는 유전자 및 이를 포함하는 살조제제 有权
标题翻译：具有杀鼠活性的蛋白质，编码其的基因和包含其的杀菌配方
公开(公告)号：KR1020080108921A
公开(公告)日：2008-12-16
申请号：KR1020080054757
申请日：2008-06-11
申请人： 한국해양과학기술원
发明人： 김상진 , 강성균 , 권개경 , 이정현 , 이현숙 , 강지현 , 손재학
IPC分类号： C12N9/50 , C12N9/00
CPC分类号： C12N9/50 , A01N63/00
摘要： The proteinase with the algicidal activity is provided to inhibit the growth of red-tide plankton, thereby processing the red-tide generation region effectively. The proteinase with the algicidal activity has an amino acid sequence selected from SEQ ID NOs:1, 4-7, 26 and 27, and is produced from Kordia algicida OT1(KCTC 11320BP). A gene encoding the proteinase with the algicidal activity has a nucleotide sequence selected from SEQ ID NOs:2, 8-11, 28 and 29. An algicidal formulation comprises the proteinase with the algicidal activity.
摘要翻译：提供具有杀藻活性的蛋白酶以抑制红潮浮游生物的生长，从而有效地处理红潮生成区域。具有杀藻活性的蛋白酶具有选自SEQ ID NO：1,47,26和27的氨基酸序列，并且由Kordia algicida OT1（KCTC 11320BP）生产。编码具有杀藻活性的蛋白酶的基因具有选自SEQ ID NO：2,8-11,28和29的核苷酸序列。杀藻剂制剂包含具有杀藻活性的蛋白酶。

7. 发明授权

KR101617362B1 서열번호 6를 포함하는 살조활성 단백질분해효소, 이를 코딩하는 유전자 및 이를 포함하는 살조제제 有权
标题翻译： 6具有编码其的杀伤活性基因的序列6的抗体及其包含的ALGICIDAL制剂
公开(公告)号：KR101617362B1
公开(公告)日：2016-05-03
申请号：KR1020140191152
申请日：2014-12-26
申请人： 한국해양과학기술원
发明人： 김상진 , 강성균 , 권개경 , 이정현 , 이현숙 , 강지현 , 손재학
IPC分类号： C12N9/52 , C12N15/52 , A01N63/00
CPC分类号： A01N63/00
摘要： 본발명은살조활성단백질분해효소, 이를코딩하는유전자및 이를포함하는살조제제에관한것으로, 본발명의단백질분해효소는살조활성이우수하므로, 적조발생지역에서적조의방제에유용하게사용될수 있다.

8. 发明公开

KR1020150014424A 서열번호 6를 포함하는 살조활성 단백질분해효소, 이를 코딩하는 유전자 및 이를 포함하는 살조제제 有权
标题翻译：具有杀伤活性的序列6的抗体，编码其的基因和包含其的碱性制剂
公开(公告)号：KR1020150014424A
公开(公告)日：2015-02-06
申请号：KR1020140191152
申请日：2014-12-26
申请人： 한국해양과학기술원
发明人： 김상진 , 강성균 , 권개경 , 이정현 , 이현숙 , 강지현 , 손재학
IPC分类号： C12N9/52 , C12N15/52 , A01N63/00
CPC分类号： A01N63/00 , C12N9/52 , C12N15/52 , Y10S435/816
摘要： The present invention relates to a protease having an algicidal activity, a gene encoding the same, and an algicidal formulation including the same. The protease of the present invention has the excellent algicidal formulation, thereby being used in controlling of red tide in a red tide occurrence area. Provided in the present invention is a method for controlling red tide, which includes the step of treating the area where red tide occurs with the algicidal formulation. Specifically, provided is a method for controlling red tide which is characterized by comprising the steps of: producing at least one protease selected from the group consisting of sequence number 1, 7, and 27 by using a Kordia algicida OT1 strain (KCTC 11320BP); and putting an algicidal formulation which contains the produced protease as an active component into sea.
摘要翻译：本发明涉及具有杀藻活性的蛋白酶，编码该蛋白酶的基因，以及包含其的杀藻剂。本发明的蛋白酶具有优异的杀藻剂配方，因此用于防治红潮发生地区的红潮。在本发明中提供了一种控制红潮的方法，其包括用杀藻剂制剂处理红潮区域的步骤。具体地说，提供一种控制红潮的方法，其特征在于包括以下步骤：通过使用Kordia algicida OT1菌株（KCTC 11320BP）制备至少一种选自序列号1，7和27的蛋白酶; 并将含有所产生的蛋白酶作为活性成分的杀藻剂制剂放入海中。

9. 发明公开

KR1020150009510A 서열번호 5를 포함하는 살조활성 단백질분해효소, 이를 코딩하는 유전자 및 이를 포함하는 살조제제 有权
标题翻译：具有杀伤活性的序列5的抗原，编码其的基因和包含其的碱性制剂
公开(公告)号：KR1020150009510A
公开(公告)日：2015-01-26
申请号：KR1020140191149
申请日：2014-12-26
申请人： 한국해양과학기술원
发明人： 김상진 , 강성균 , 권개경 , 이정현 , 이현숙 , 강지현 , 손재학
IPC分类号： C12N9/52 , C12N15/52 , A01N63/00
CPC分类号： A01N63/00 , C12N9/52 , C12N15/52 , Y10S435/816
摘要： The present invention relates to a protease of sequence number 5 having algicidal activity, a gene encoding the same, and an algicidal preparation including the same. The protease of the present invention has excellent algicidal activity, and thus can be useful in controlling red algal blooms in a red tide occurrence area. Provided in the present invention are a protease with algicidal activity having any one amino acid sequence among sequence number 1, 4 to 7, 26, and 27, and a gene encoding the protease.
摘要翻译：本发明涉及具有杀藻活性的序列号5的蛋白酶，编码该蛋白酶的基因，以及包含其的杀藻剂制剂。本发明的蛋白酶具有优异的杀藻活性，因此可用于防治红潮发生地区的红藻。本发明提供具有杀菌活性的蛋白酶，其具有序列号1,4至7,26和27之间的任何一个氨基酸序列，以及编码该蛋白酶的基因。

10. 发明公开

KR1020090063644A 단백질분해효소 및 이를 코딩하는 유전자 无效
标题翻译：编码它们的基因和基因
公开(公告)号：KR1020090063644A
公开(公告)日：2009-06-18
申请号：KR1020070131091
申请日：2007-12-14
申请人： 한국해양과학기술원
发明人： 김상진 , 강성균 , 권개경 , 이정현 , 강지현
IPC分类号： C12N9/50 , C12N9/00
摘要： A protease and gene coding the same are provided to ensure excellent algicidal activity and usefully prevent the red tide. A protease comprises amino acids of sequence number 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, 23, 25, 27, 29, 31, 33, 35, 37, 39, 41, 43, 45, 47, 49, 51, 53, 55, 57, 59, 61, 63, 65, 67, 69, 71, 73, 75, 77, 79, 81, 83, 85, 87, 89, 91, 93, 95, 97, 99, 101, 103, 105, 107, 109, 111, 113, 115, 117, 119, 121, 123, 125, 127, 129, 131, 133, 135, 137 or 139. A polynucleotide coding the protease comprises base of the sequence number 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36, 38, 40, 42, 44, 46, 48, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72, 74, 76, 78, 80, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100, 102, 104, 106, 108, 110, 112, 114, 116, 118, 120, 122, 124, 126, 128, 130, 132, 134, 136, 138 or 140. The protease is secreted from a kordia algicida OT-1(KCTC 8814P) strain which kills a skeletonema costatum.
摘要翻译：提供了一种蛋白酶及其编码基因，以确保优异的杀藻活性，有效防止红潮。一种蛋白酶包含序列号1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35,37,39,41,46,33,39,39,39,39,39,39,31,39,39,39,39,39,39,39,39,39,39,39,39,39,39,39,39,39,39,39,39,39 43，45，47，49，51，53，55，57，59，61，63，65，67，69，71，73，75，77，79，81，83，85，87，89， 93,95,97,99,101,103,105,107,109,111,113,115,117,119,121,123,125,127,129,131,133,135,137或139.一种多核苷酸编码蛋白酶的步骤包括序列号2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32,34,36,38,40,42的碱基，44，46，48，50，52，54，56，58，60，62，64，66，68，70，72，74，76，78，80，82，84，86，88，90，92 ，94,96,98,100,102,104,106,108,110,112,114,116,118,120,122,124,126,128,130,132,134,136,138或140中。蛋白酶是从一个kordia algicida OT-1（KCTC 8814P）菌株分泌的，该菌株杀死骨骼水肿。

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