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    • 5. 发明公开
    • 알츠하이머병 발병률 예측 장치
    • 预测阿尔茨海默病疾病流行率的装置
    • KR1020140119486A
    • 2014-10-10
    • KR1020130035205
    • 2013-04-01
    • 한국전자통신연구원
    • 채철주정교일송기봉
    • G01N21/64G01N33/483
    • Disclosed are a device and a method for predicting the incidence rate of the Alzheimer′s disease by utilizing a beta-amyloid concentration, a p-FET measurement value, and a PMT measurement value as input data, extracting the feature values of the input data, and applying the feature values to a pattern recognizing algorithm. The device comprises: a feature extracting part for extracting the feature values through the recognition of a pattern by comparing a beta-amyloid concentration value contained in a sample to be measured, a photosensitive field-effect transistor measurement value, and a photo multiplier tube measurement value, which are inputted from the outside, with pre-stored initial values; and an incidence rate predicting part for predicting the incidence rate of the Alzheimer′s disease based on the extracted feature values. The photosensitive field-effect transistor measurement value is obtained by measuring the photoelectric current of light emitted by exciting light while the sample in which the beta-amyloid and fluorescent substances are combined is fixed in the sensing section of a photosensitive field-effect transistor, and the photo multiplier tube measurement value is obtained by measuring the number of photons in the light emitted by exciting the light to the same sample used in the measurement of the photoelectric current.
    • 公开了一种通过利用β-淀粉样蛋白浓度,p-FET测量值和PMT测量值作为输入数据来预测阿尔茨海默病发病率的装置和方法,提取输入数据的特征值 并且将特征值应用于模式识别算法。 该装置包括:特征提取部分,用于通过比较待测样品中包含的β-淀粉样蛋白浓度值,光敏场效应晶体管测量值和光倍增管测量值,通过识别图案来提取特征值 值,其从外部输入预先存储的初始值; 以及基于提取的特征值来预测阿尔茨海默病发病率的发生率预测部分。 光敏场效应晶体管测量值是通过测量激发光发射的光的光电流而得到的,而其中组合β-淀粉样蛋白和荧光物质的样品固定在感光场效应晶体管的感测部分中,以及 光电倍增管测量值是通过测量通过将光激发到与光电流测量中使用的相同样品发出的光中的光子数来获得的。