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    • 5. 发明公开
    • 애기나리 함유 약학적 조성물 또는 식품 조성물
    • 包含色氨酸的药物或食品组合物
    • KR1020140083865A
    • 2014-07-04
    • KR1020130137507
    • 2013-11-13
    • 한국식품연구원
    • 김혜영류미라김경박민이유미
    • A61K36/896A61P3/10A61P3/00
    • The present invention relates to a pharmaceutical or food composition which reduces side effects, improves safety, and facilitates to stimulate enteroendocrine cells. The composition comprises Disporum smilacinum extract as an effective ingredient. The composition of the present invention can be effectively used as a pharmaceutical or food composition for prevention and alleviation of diabetes, alleviation of heart diseases, appetite suppression, prevention and alleviation of obesity, alleviation of arteriosclerosis, neuroprotective effects, treatment or alleviation of liver diseases or the like. In addition, the composition of the present invention can promote the secretion of GLP-1, CCK or 5-HT, or the activation of hTGR5.
    • 本发明涉及减少副作用,改善安全性并促进刺激肠内分泌细胞的药物或食物组合物。 该组合物包含茜草提取物作为有效成分。 本发明的组合物可以有效地用作预防和减轻糖尿病,缓解心脏病,抑制食欲,预防和减轻肥胖,减轻动脉硬化,神经保护作用,治疗或减轻肝脏疾病的药物或食品组合物 或类似物。 此外,本发明的组合物可以促进GLP-1,CCK或5-HT的分泌或hTGR5的活化。
    • 6. 发明公开
    • 세발나물 함유 약학적 조성물 또는 식품 조성물
    • 包含海藻的药物或食品组合物
    • KR1020140083864A
    • 2014-07-04
    • KR1020130137506
    • 2013-11-13
    • 한국식품연구원
    • 김혜영류미라김경박민이유미
    • A61K36/36A61P3/04A61P3/00
    • The present invention relates to a pharmaceutical or food composition which reduces the side effects so as to be safe and which is highly active for stimulating enteroendocrine cells, and comprises spergularia marina extract as an effective ingredient. The composition of the present invention can be effectively used as a pharmaceutical or food composition for appetite suppression, anti-obesity effects, alleviation of heart diseases, alleviation or treatment of digestive disorders and malabsorption, treatment or alleviation of arteriosclerosis, neuroprotective effects, treatment or alleviation of liver diseases or the like. In addition, the composition of the present invention can promote the secretion of GLP-1, CCK or 5-HT, or the activation of hTGR5, and can activate hGPR119, α-gustducin, and TRP and act as a TRPA1 activator.
    • 本发明涉及减少副作用以安全并且对于刺激肠内分泌细胞具有高度活性的药物或食品组合物,并且包括作为有效成分的精液提取物。 本发明的组合物可以有效地用作食欲抑制,抗肥胖作用,心脏病减轻,消化障碍的缓解或治疗,吸收不良,动脉硬化的治疗或缓解,神经保护作用,治疗或 减轻肝病等。 此外,本发明的组合物可以促进GLP-1,CCK或5-HT的分泌或hTGR5的活化,并且可以激活hGPR119,α-内含物和TRP并作为TRPA1激活剂。