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1. 发明授权

KR101705760B1 감태 추출물을 포함하는 로타바이러스 감염의 예방 또는 치료용 조성물 有权
标题翻译：用于预防或治疗轮状病毒感染的组合物的组合物，包括ecklonia cava
公开(公告)号：KR101705760B1
公开(公告)日：2017-02-13
申请号：KR1020100006228
申请日：2010-01-22
申请人： 한국생명공학연구원
发明人： 이우송 , 노문철 , 류영배 , 박수진 , 장종선 , 권형준 , 김하현 , 정형재
IPC分类号： A61K36/03 , A61P31/12
摘要： 본발명은감태추출물또는이의분획물을포함하는로타바이러스감염의예방또는치료용조성물에관한것으로, 감태추출물또는이의분획물이항로타바이러스의효과를가지고, 다양한로타바이러스에대해살바이러스및 세포변성억제효과를동시에나타내므로로타바이러스감염의예방또는치료에유용하게사용될수 있다.
摘要翻译：目的：提供含有Ecklonia cava提取物或用于预防或治疗轮状病毒感染的提取物级分的组合物以抑制细胞变性。构成：用于预防或治疗轮状病毒感染的组合物含有Ecklonia cava提取物或提取物的级分作为活性成分。萃取液用水，C1-C4的醇或其混合溶剂制备。馏分是己烷馏分，乙酸乙酯馏分或水馏分。轮状病毒是人，猪，牛或山羊轮状病毒。组合物是药物或食物组合物。药物组合物以片剂，丸剂，粉剂，颗粒剂，胶囊剂，悬浮液，乳剂，糖浆，灭菌溶液，非水溶剂，乳液或悬浮液的形式制备。

2. 发明公开

KR1020110086473A 감태 추출물을 포함하는 코로나 바이러스 감염의 예방 또는 치료용 조성물 및 3ＣＬ 프로테아제 활성의 억제용 조성물 无效
标题翻译：用于预防或治疗冠状病毒感染的组合物和用于抑制包含ECKLONIA CAVA的3C样蛋白的活性的组合物
公开(公告)号：KR1020110086473A
公开(公告)日：2011-07-28
申请号：KR1020100006227
申请日：2010-01-22
申请人： 한국생명공학연구원
发明人： 이우송 , 노문철 , 류영배 , 박수진 , 장종선 , 권형준 , 김하현 , 정형재
IPC分类号： A61K36/03 , A61P31/12
CPC分类号： A61K36/03 , A23L33/00
摘要： PURPOSE: A composition containing Ecklonia cava extract or fraction of the extract for preventing or treating coronaviral infection is provided to suppress 3CL protease activity. CONSTITUTION: A composition for preventing or treating coronaviral infection contains Ecklonia cava extract or fraction of the extract as an active ingredient. The extract is isolated using water, alcohol of C1-C4, or mixture solvent thereof. The fraction is a hexane fraction, ethyl acetate fraction, or water fraction. The composition is a pharmaceutical or food composition. The pharmaceutical composition is manufactured in the form of tablet, pill, powder, granule, capsule, suspension, emulsion, syrup, non-aqueous solvent, suspension, or suppository. A composition for suppressing 3CL protease activity contains the extract or fraction of the extract as an active ingredient.
摘要翻译：目的：提供含有Ecklonia cava提取物或提取物级分用于预防或治疗冠状病毒感染的组合物以抑制3CL蛋白酶活性。构成：用于预防或治疗冠状病毒感染的组合物含有Ecklonia cava提取物或提取物的级分作为活性成分。使用水，C1-C4的醇或其混合溶剂分离提取物。馏分是己烷馏分，乙酸乙酯馏分或水馏分。组合物是药物或食物组合物。药物组合物以片剂，丸剂，粉末，颗粒剂，胶囊剂，悬浮液，乳剂，糖浆剂，非水溶剂，悬浮液或栓剂的形式制备。用于抑制3CL蛋白酶活性的组合物含有提取物的提取物或级分作为活性成分。

3. 发明公开

KR1020110057010A 폴리페놀성 화합물을 포함하는 인플루엔자 바이러스 감염의 예방 및 치료용 조성물 및 뉴라미니데이즈 활성의 억제용 조성물 有权
标题翻译：用于预防和治疗流感病毒和组合物的组合物，用于抑制包含聚苯酚化合物的神经酰胺糖苷酶的活性
公开(公告)号：KR1020110057010A
公开(公告)日：2011-05-31
申请号：KR1020090113538
申请日：2009-11-23
申请人： 한국생명공학연구원
发明人： 이우송 , 노문철 , 박수진 , 류영배 , 장종선 , 정형재 , 권형준 , 김하현
IPC分类号： A61K31/121 , A61P31/16 , A61K31/7034 , A61K31/7042
摘要： PURPOSE: A pharmaceutical composition containing polyphenolic compounds such as chalcones or flavonoids is provided to prevent or treat influenza viral infection. CONSTITUTION: A composition for preventing and treating influenza viral infection contains a compound of chemical formula 1. The diseases caused by influenza viral infection include flu, pharyngolaryngitis, bronchitis, and pneumonia. The composition is a pharmaceutical, food, or external use product. The pharmaceutical composition is selected from the group consisting of tablet, pill, powder, capsule, suspension, emulsion, syrup, sterilized solution, and suppository.
摘要翻译：目的：提供含有多酚化合物如查尔酮或类黄酮的药物组合物，用于预防或治疗流感病毒感染。构成：用于预防和治疗流感病毒感染的组合物含有化学式1的化合物。由流感病毒感染引起的疾病包括流感，咽喉炎，支气管炎和肺炎。组合物是制药，食品或外用产品。药物组合物选自片剂，丸剂，粉剂，胶囊，悬浮液，乳剂，糖浆，灭菌溶液和栓剂。

4. 发明授权

KR101138461B1 감초 추출물을 포함하는 로타바이러스 감염의 예방 또는 치료용 조성물 有权
标题翻译：用于预防或治疗包含甘草的轮状病毒感染的组合物的组合物
公开(公告)号：KR101138461B1
公开(公告)日：2012-04-26
申请号：KR1020100013543
申请日：2010-02-12
申请人： 한국생명공학연구원
发明人： 이우송 , 노문철 , 류영배 , 박수진 , 장종선 , 권형준 , 김하현 , 정형재
IPC分类号： A61K36/236 , A61P31/12
CPC分类号： A61K36/484 , A23L7/198 , A23L33/105 , A23V2002/00 , A61K31/05 , A61K31/085 , A61K31/343 , A61K31/352 , A61K31/353 , A61K2300/00 , A23V2200/324 , A23V2250/21 , A23V2250/2132
摘要： 본 발명은 감초 추출물 또는 이의 분획물을 포함하는 로타바이러스 감염의 예방 또는 치료용 조성물에 관한 것으로, 감초 추출물 또는 이의 분획물이 항로타바이러스의 효과를 가지고, 다양한 로타바이러스에 대해 살바이러스 및 세포변성 억제효과를 동시에 나타내므로 로타바이러스 감염의 예방 또는 치료에 유용하게 사용될 수 있다.

5. 发明授权

KR101128088B1 코로나 바이러스 감염의 예방 또는 치료용 조성물 및 ３ＣＬ 프로테아제 활성의 억제용 조성물 有权
标题翻译：用于预防或治疗冠状病毒的组合物和用于抑制3C样蛋白酶活性的组合物
公开(公告)号：KR101128088B1
公开(公告)日：2012-04-12
申请号：KR1020090125042
申请日：2009-12-15
申请人： 한국생명공학연구원
发明人： 이우송 , 노문철 , 박수진 , 류영배 , 장종선 , 정형재 , 권형준 , 김하현
IPC分类号： A61K36/37 , A61P31/12 , A23L1/30 , A61K31/65
摘要： PURPOSE: A composition containing Celastrus orbiculatus extract or Tripterygium regelii sprague et takeda extract is provided to prevent or treat corona virus infection and to suppress 3CL protease. CONSTITUTION: A composition for preventing or treating corona virus infection contains Celastrus orbiculatus extract or fraction thereof, or Tripterygium regelii sprague et takeda extract or extract thereof. The extract is isolated using water, C1-C4 alcohol, or mixture solvent. The fraction is isolated using hexane fraction, ethyl acetate fraction, or water fraction. The corona virus is SARS, porcine, or bovine corona virus. A pharmaceutical composition is used in the form of tablet, pill, powder, granule, capsule, suspension, emulsion, syrup, freeze-dried formulation, or suppository. A composition for preventing or treating corona virus infection contains a compound of chemical formula 1 as an active ingredient.

6. 发明公开

KR1020110086474A 감태 추출물을 포함하는 로타바이러스 감염의 예방 또는 치료용 조성물 有权
标题翻译：用于预防或治疗包含ECKLONIA CAVA的罗非鱼感染的组合物组合物
公开(公告)号：KR1020110086474A
公开(公告)日：2011-07-28
申请号：KR1020100006228
申请日：2010-01-22
申请人： 한국생명공학연구원
发明人： 이우송 , 노문철 , 류영배 , 박수진 , 장종선 , 권형준 , 김하현 , 정형재
IPC分类号： A61K36/03 , A61P31/12
CPC分类号： A61K36/03 , A23L33/00
摘要： PURPOSE: A composition containing Ecklonia cava extract or fraction of the extract for preventing or treating rotaviral infection is provided to suppress cell denaturation. CONSTITUTION: A composition for preventing or treating rotaviral infection contains Ecklonia cava extract or fraction of the extract as an active ingredient. The extract is prepared using water, alcohol of C1-C4, or mixture solvent thereof. The fraction is a hexane fraction, ethyl acetate fraction, or water fraction. The rotavirus is human, porcine, bovine, or goat rotavirus. The composition is a pharmaceutical or food composition. The pharmaceutical composition is manufactured in the form of tablet, pill, powder, granule, capsule, suspension, emulsion, syrup, sterilized solution, non-aqueous solvent, emulsion, or suspension.
摘要翻译：目的：提供含有Ecklonia cava提取物或用于预防或治疗轮状病毒感染的提取物级分的组合物以抑制细胞变性。构成：用于预防或治疗轮状病毒感染的组合物含有Ecklonia cava提取物或提取物的级分作为活性成分。萃取液用水，C1-C4的醇或其混合溶剂制备。馏分是己烷馏分，乙酸乙酯馏分或水馏分。轮状病毒是人，猪，牛或山羊轮状病毒。组合物是药物或食物组合物。药物组合物以片剂，丸剂，粉剂，颗粒剂，胶囊剂，悬浮液，乳剂，糖浆，灭菌溶液，非水溶剂，乳液或悬浮液的形式制备。

7. 发明公开

KR1020110121493A 쿠마린계 화합물을 포함하는 뉴라미니데이즈 활성의 억제용 조성물 및 인플루엔자 바이러스 감염 질환의 예방 및 치료용 조성물 有权
标题翻译：用于抑制神经酰胺糖激酶活性的组合物和用于预防和治疗包含COUMARIN化合物的流感病毒性疾病的组合物
公开(公告)号：KR1020110121493A
公开(公告)日：2011-11-07
申请号：KR1020100041103
申请日：2010-04-30
申请人： 한국생명공학연구원
发明人： 이우송 , 노문철 , 박수진 , 류영배 , 장종선 , 권형준 , 정형재 , 김하현
IPC分类号： A61K31/37 , A61P31/16
摘要： PURPOSE: A composition containing courmarin compounds is provided to prevent and treat influenza viral infection diseases is provided to suppress neuraminidase activity. CONSTITUTION: A composition for preventing and treating influenza viral infection contains a compound of chemical formula 1 as an active ingredient. The compound of chemical formula 1 is isolated from Glycyrrhizae radix. The influenza virus is type A influenza virus, type B influenza virus, or type C influenza virus. The composition is a pharmaceutical, food, or non-medical product composition. A composition for suppressing neuraminidase activity contains the compound of chemical formula 1 as an active ingredient.
摘要翻译：目的：提供含有勇气化合物的组合物，以预防和治疗流感病毒感染疾病，以抑制神经氨酸酶活性。构成：用于预防和治疗流感病毒感染的组合物含有化学式1化合物作为活性成分。化学式1的化合物从甘草中分离出来。流感病毒是A型流感病毒，B型流感病毒或C型流感病毒。该组合物是药物，食品或非医疗产品组合物。用于抑制神经氨酸酶活性的组合物含有化学式1的化合物作为活性成分。

8. 发明公开

KR1020110093474A 감초 추출물을 포함하는 로타바이러스 감염의 예방 또는 치료용 조성물 有权
标题翻译：组合物用于预防或治疗包含糖尿病尿路感染的罗非鱼感染的组合物
公开(公告)号：KR1020110093474A
公开(公告)日：2011-08-18
申请号：KR1020100013543
申请日：2010-02-12
申请人： 한국생명공학연구원
发明人： 이우송 , 노문철 , 류영배 , 박수진 , 장종선 , 권형준 , 김하현 , 정형재
IPC分类号： A61K36/236 , A61P31/12
CPC分类号： A61K36/484 , A23L7/198 , A23L33/105 , A23V2002/00 , A61K31/05 , A61K31/085 , A61K31/343 , A61K31/352 , A61K31/353 , A61K2300/00 , A23V2200/324 , A23V2250/21 , A23V2250/2132
摘要： PURPOSE: A composition containing Glycyrrhiza uralensis Fischer extract or fraction is provided to ensure anti-rotavirus effect and to prevent or treat rotavirus infection. CONSTITUTION: A composition for preventing or treating rotavirus infection contains Glycyrrhiza uralensis Fischer extract or fraction as an active ingredient. The extract is isolated using water, alcohol of C1-C4, or mixture solvent thereof. The fraction is a hexane, ethyl acetate, or water fraction. The rotavirus is human porcine, bovine, or goat rotavirus. The composition is a pharmaceutical or food composition. The pharmaceutical composition is used in the form of tablet, powder, pill, granule, capsule, suspension, emulsion, syrup, suspension, or suppository.
摘要翻译：目的：提供含有甘草的费舍尔提取物或级分的组合物，以确保抗轮状病毒的作用并预防或治疗轮状病毒感染。构成：用于预防或治疗轮状病毒感染的组合物含有甘草甙提取物或级分作为活性成分。使用水，C1-C4的醇或其混合溶剂分离提取物。该馏分是己烷，乙酸乙酯或水馏分。轮状病毒是人类猪，牛或山羊轮状病毒。组合物是药物或食物组合物。药物组合物以片剂，粉剂，丸剂，颗粒剂，胶囊剂，悬浮剂，乳剂，糖浆剂，悬浮剂或栓剂的形式使用。

9. 发明公开

KR1020110068191A 코로나 바이러스 감염의 예방 또는 치료용 조성물 및 ３ＣＬ 프로테아제 활성의 억제용 조성물 有权
标题翻译：用于预防或治疗冠状病毒的组合物和用于抑制3C-样蛋白的活性的组合物
公开(公告)号：KR1020110068191A
公开(公告)日：2011-06-22
申请号：KR1020090125042
申请日：2009-12-15
申请人： 한국생명공학연구원
发明人： 이우송 , 노문철 , 박수진 , 류영배 , 장종선 , 정형재 , 권형준 , 김하현
IPC分类号： A61K36/37 , A61P31/12 , A23L1/30 , A61K31/65
CPC分类号： A61K36/37 , A23L29/035 , A61K9/00 , A61K31/122 , A61K31/192 , A61K31/216 , A61K2236/33 , Y10S514/849
摘要： PURPOSE: A composition containing Celastrus orbiculatus extract or Tripterygium regelii sprague et takeda extract is provided to prevent or treat corona virus infection and to suppress 3CL protease. CONSTITUTION: A composition for preventing or treating corona virus infection contains Celastrus orbiculatus extract or fraction thereof, or Tripterygium regelii sprague et takeda extract or extract thereof. The extract is isolated using water, C1-C4 alcohol, or mixture solvent. The fraction is isolated using hexane fraction, ethyl acetate fraction, or water fraction. The corona virus is SARS, porcine, or bovine corona virus. A pharmaceutical composition is used in the form of tablet, pill, powder, granule, capsule, suspension, emulsion, syrup, freeze-dried formulation, or suppository. A composition for preventing or treating corona virus infection contains a compound of chemical formula 1 as an active ingredient.
摘要翻译：目的：提供含有西葫芦提取物或雷公藤雷公藤提取物的组合物，用于预防或治疗电晕病毒感染并抑制3CL蛋白酶。构成：用于预防或治疗电晕病毒感染的组合物含有西葫芦提取物或其部分，或雷公藤雷公藤提取物或其提取物。使用水，C1-C4醇或混合溶剂分离提取物。使用己烷级分，乙酸乙酯级分或水级分分离级分。电晕病毒是SARS，猪或牛冠状病毒。药物组合物以片剂，丸剂，粉剂，颗粒剂，胶囊剂，悬浮液，乳剂，糖浆剂，冷冻干燥制剂或栓剂的形式使用。用于预防或治疗电晕病毒感染的组合物含有化学式1的化合物作为活性成分。

10. 发明授权

KR101115063B1 인플루엔자 바이러스 감염의 예방 및 치료용 조성물 및 뉴라미니데이즈 활성의 억제용 조성물 失效
标题翻译：用于预防和治疗流感病毒的组合物和用于抑制神经氨酸酶活性的组合物
公开(公告)号：KR101115063B1
公开(公告)日：2012-03-07
申请号：KR1020090113540
申请日：2009-11-23
申请人： 한국생명공학연구원
发明人： 이우송 , 노문철 , 박수진 , 장종선 , 류영배 , 권형준 , 김하현
IPC分类号： A61K36/9064 , A61P31/16 , A23L1/30 , A61K31/715
摘要： 본발명은초두구추출물을포함하는인플루엔자바이러스감염의예방및 치료용조성물및 뉴라미니데이즈활성의억제용조성물에관한것으로, 초두구추출물, 용매분획물및 이로부터분리된다당류분획물이 H1N1 또는 H9N2 인플루엔자바이러스의 MDCK 세포감염을억제하여바이러스의증식을억제하고뉴라미니데이즈의활성을저해하는효과를나타내므로인플루엔자바이러스감염의예방및 치료에유용하게사용될수 있다.

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