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    • 7. 发明授权
    • 텍토리딘 또는 그 비배당체를 포함하는 항암용 조성물
    • 텍토리딘또는그비배당체를포함하는항암용조성물물
    • KR100740184B1
    • 2007-07-18
    • KR1020060019940
    • 2006-03-02
    • 한국과학기술연구원
    • 정상훈노주원이샛별차광현
    • A61K31/352A61P35/00
    • An anti-cancer composition containing tectoridin or aglycone thereof is provided to increase metabolism of carcinogens in cancer cells, inhibit growth of cancer cells, induce no colony formation of cancer cells and reduce expressions of genes associated with cancer cell generation and metastasis, so that the composition is useful for treatment of female cancers. The composition for treating female cancer or disease associated with female hormone contains tectoridin or aglycone thereof which is obtained by (a) extracting Belamcanda chinensis DC. rhizome with an organic solvent, and (b) fractionating the organic solvent extract of Belamcanda chinensis DC. rhizome by subjecting it to silica gel chromatography, wherein the female cancer includes breast cancer, endometrical carcinoma and ovarian cancer, and the disease associated with female hormone includes telangiectasia, osteoporosis and vein thrombosis.
    • 提供含有鸢尾黄素或其苷配基的抗癌组合物,用于增加癌细胞中致癌物质的代谢,抑制癌细胞的生长,诱导癌细胞的集落形成,减少与癌细胞生成和转移有关的基因的表达, 组合物对于治疗女性癌症是有用的。 用于治疗女性癌症或与雌激素有关的疾病的组合物含有通过(a)提取Belamcanda chinensis DC获得的鸢尾苷或其苷元。 (b)分馏Belamcanda chinensis DC的有机溶剂提取物。 通过对其进行硅胶层析,其中女性癌症包括乳腺癌,内分泌癌和卵巢癌,并且与女性激素有关的疾病包括毛细血管扩张症,骨质疏松症和静脉血栓形成。