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    • 2. 发明公开
    • 슬러리 농도의 결정
    • 浆液浓度的测定
    • KR1020100065140A
    • 2010-06-15
    • KR1020107000151
    • 2008-07-04
    • 지이 헬스케어 바이오-사이언시스 에이비
    • 룬트크비스트,조아킴로브만,에스피어어링,한노
    • G01N30/56B01D15/20G01F23/02B01J8/00
    • G01N30/56B01D15/206G01F23/292G01F23/296G01N2030/565
    • A method for determining the concentration of a chromatographic medium in a liquid slurry compiises the steps of providing a column (1) having a top end (3) and a bottom end (2) and adapted to retain a chromatographic medium therein, introducing a defined volume of the slurry (15) into the column (1), providing a liquid flow through the column (1) from the top end to the bottom end of the column to settle the chromatographic medium in the column, measuring the bed height of the consolidated chromatographic medium or a value related thereto, and determining from the measured bed height or value related thereto the concentration, or a value related to the concentration of the chromatographic medium in the slurry. A device for performing the method as well as the use of the method in packing of especially large scale columns are also disclosed.
    • 用于确定液体浆料中色谱介质浓度的方法包括提供具有顶端(3)和底端(2)的柱(1)的步骤,并适于在其中保留色谱介质,引入限定的 将浆液(15)的体积进入塔(1),提供从塔(1)的塔顶部到塔底的液体流动,以将色谱介质沉淀在塔中,测量床的高度 固定的色谱介质或与其相关的值,并从测量的床高度或与其相关的值确定浓度,或与浆料中色谱介质浓度相关的值。 还公开了一种用于执行该方法的装置以及该方法在特别大规模柱的包装中的使用。